Negative Epistasis | Topics

Articles tagged with Negative Epistasis

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plant

Researchers at Cold Spring Harbor Laboratory discover that adding beneficial traits can have negative consequences due to epistasis. They find a case of negative epistasis in a tomato plant and show how to exploit this knowledge to unlock untapped yield potential by adjusting the dosage of genes responsible for different traits.

Sex: Why bother? Evolutionary mysteries probed at UH

Ricardo Azevedo's study using a computational model suggests that sexual reproduction can lead to the evolution of negative epistasis, which confers an evolutionary advantage on sexually reproducing organisms. This finding implies that sex may be self-reinforcing, leading to increased robustness in populations.