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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Food for our guts: Human microbes feed on plant sugars

New research reveals that human gut bacteria use plant N-glycans as nutrients, enabling better management of good gut health. The discovery has biotechnological applications, such as reducing allergenic responses to food and medicine.

Researchers propose new framework for regulating engineered crops

Researchers suggest a new approach for regulating genetically engineered (GE) crops by examining the specific characteristics of the crop itself. The '-omics' methods can be used to scan new crop varieties for unexpected DNA changes, eliminating the need for safety testing if the product is substantially equivalent to existing varieties.

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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

When mothers shut down the fathers’ genes in the embryo

Researchers found that Marchantia liverworts completely inactivate paternal genes in embryos, ensuring proper development. The mechanism involves Polycomb Repressive Complex 2 and maintains haploid dosage despite the short diploid phase.

Self-pollinating plant shows rapid loss of genetic variation

A self-pollinating monkeyflower plant lost 13-24% of its genetic variation within nine generations when isolated from bumble bees. This rapid loss of genetic variation could have devastating impacts on the plant's ability to adapt to changing environments, highlighting the importance of pollinators for plant survival.

Growing cereal crops with less fertilizer

Researchers at the University of California, Davis have discovered a new pathway for cereals to capture nitrogen from the air, reducing the need for expensive fertilizers. The breakthrough could save farmers billions of dollars annually and benefit the environment by decreasing nitrogen pollution.

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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Understanding cooperation and conflict in plant symbionts

Researchers examine the genomic variations of 191 microbial strains paired with their host plants to understand cooperation and conflict. They found that 80% of symbiont genes align with the host's interest, often paying for them to be beneficial despite competing interests.

Tree fern genome provides insights into its evolution

The study of flying spider-monkey tree fern genome provides insights into fern evolution and arborescence. Ferns developed vascular tissues, including xylem and phloem, to transport water, nutrients, and food, which is a key innovation in land plant evolution.

What sea cucumbers can teach us about self-defense

Researchers have discovered how sea cucumbers produce defensive chemicals using genome mining techniques. The animals' unique ability to biosynthesize toxins has been found to be linked to the diversion of a sterol-producing enzyme, resulting in the production of valuable medicinal compounds.

Wild tomato genome will benefit domesticated cousins

A reference genome for the wild relative of cultivated tomatoes has been developed to improve crop yields and disease resistance. Researchers have also created online tools to facilitate gene discovery and analysis.

Building block for a longer life

Heidelberg University researchers have identified a key protein HYPK that regulates N-terminal acetylation, prolonging plant protein life and enhancing drought resistance. This mechanism appears to be ancient, retained across various organisms.

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New alga species named for poet Amanda Gorman

Researchers at Cornell University named a new green alga species after poet Amanda Gorman, who inspired them during a challenging year. The discovery was made by accident while studying hornwort plants and contains unique DNA from fungi and bacteria.

New species of alga named for poet Amanda Gorman

A group of researchers discovered a new species of green algae, Gormaniella terricola, in Central New York State. The alga's unique chloroplast genome was found to contain DNA from fungi and bacteria, highlighting the importance of horizontal transfer.

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Understanding the genomic modifications in transgenic papaya

A new study has identified genomic modifications in the transgenic papaya 'SunUp', which was developed to resist the papaya ringspot virus. The researchers used advanced sequencing technologies to read long stretches of DNA and found that the insertion did not cause any change in gene expression.

For plant geneticists, some genes are double the trouble

Researchers found that gene duplications can complicate crop improvements, with some plants showing little effect despite similar mutations. This study highlights the need to understand evolutionary changes in plant genomes to develop more predictable crop improvements.

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The hardy wild grass that could save our bread

A team of researchers identified a stem rust resistance gene from wild goat grass species Aegilops sharonensis, which can be cross-bred into wheat for immunity against deadly crop pathogens. The genetic potential of this hardy relative has been largely unexplored and holds promise for reducing the threat of the stem rust disease.

Understanding rust resistance in bread wheat

Researchers have identified a key gene that confers stripe rust resistance in bread wheat, providing hope for improving crop yields and ensuring global food security. The discovery was made possible by the assembly of the highest-quality genome to date for bread wheat using advanced DNA sequencing techniques.

A new molecular family tree of grasses

A new molecular study of grasses reveals a clear picture of their evolutionary relationships, shedding light on the evolution of C4 photosynthesis involved in heat and drought tolerance. The research provides evidence that this type of photosynthesis evolved independently multiple times within different grass lineages.

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Nanocarrier spray: Better crops without genetic modification

Researchers at RIKEN CSRS have developed a non-transgenic method to modify plant genes using a bioactive molecule spray, which can be used to improve crop yield and resistance to pests. The technique has shown promising results in improving economically desirable quality traits in crops.

Researchers discover when pollen comes of age

A new study from the University of Georgia reveals that pollen begins expressing its own genome at a specific point in its life cycle. This discovery has significant implications for plant breeding, as it allows researchers to predict how plant species adapt to environmental changes and potentially speed up crop development.

CROPSR: A new tool to accelerate genetic discoveries

CROPSR, an open-source software tool, accelerates CRISPR experiment design and evaluation by addressing challenges in complex crop genomes. The genome-wide approach significantly shortens the time required to design a CRISPR experiment, reducing failed experiments.

Gene important in soybean protein content found after 30-year search

University of Illinois researchers found a key gene responsible for increasing soybean protein content by approximately 2%. The discovery could lead to significant increases in protein production, addressing global food security issues. However, the gene's function is unclear and may involve the plant's circadian machinery.

Clearer distinction needed between GMOs and genome-edited organisms

Researchers from Hokkaido University have proposed a framework to clarify the distinction between genetically modified organisms (GMOs) and genome-edited organisms (GEOs). The framework considers scientific, ethical, and social factors to determine whether an organism is a GMO or GEO. The proposal aims to enhance regulatory reliability...

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Beating the odds in mutation’s game of chance

Researchers found that plants have evolved a way to protect their most important genes from mutation, which has significant implications for understanding crop domestication and cancer. The study discovered non-random patterns in DNA mutations, with essential genes overrepresented in regions where mutations are rare.

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Daring to leave gaps in the genome

Researchers developed a new method to complete genetic data gaps using haplotype blocks, improving breeding efficiency in plants. The approach has shown comparable quality to collecting more information from DNA strands, reducing costs in animal and plant breeding.

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Latin American rice breeding gets a boost from genomic tools

New research enables regionally relevant eating-quality traits to be selected early in breeding programs, saving time and effort. Genetic markers associated with 10 grain-quality traits have been identified, which can now be used by rice breeders in Latin America and potentially worldwide.

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Big differences found in male and female jojoba plant sex genes

Researchers identified a wide divergence of sex chromosomes in jojoba plants, which could lead to the development of a DNA test to identify male and female plants. The study reveals that male and female jojoba plants have diverged genetically due to environmental stress, with differing reproductive resource allocation requirements.

Peeling back the layers of the onion genome

Researchers at Yamaguchi University have successfully assembled the genetic map of the onion genome, revealing over 540,000 possible genes. The findings also suggest that functional gene regions are evenly distributed across the genome, highlighting the need for careful examination to determine gene functionality.

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Unlocking the secrets to sorghum’s adaptability

A reservoir of genes allowing sorghum to adapt to environmental stresses has been identified from 13 contrasting genomes. This genetic diversity is valuable for breeders, enabling them to improve crop yield and resilience. The analysis, led by the University of Queensland, provides unprecedented insights into the genome's dynamic nature.

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White clover’s toxic tricks traced to its hybridization

Research at Washington University in St. Louis reveals that white clover's chemical defense against insect pests comes from both of its parental species, not just one as previously thought. The plant's ecological success can be attributed to this cyanogenesis process.

Herbicide resistance no longer a black box for scientists

Researchers identify gene regions responsible for non-target-site herbicide resistance in waterhemp, a key step towards early detection and management tools. By analyzing the genome of waterhemp, scientists have narrowed down the genetic regions controlling resistance to two areas, paving the way for further studies.

New carnivorous plant must balance trapping prey and being pollinated

Researchers have discovered a new carnivorous plant, Triantha occidentalis, that traps insects near its insect-pollinated flowers, avoiding the death of potential pollinators. The plant's sticky hairs only entrap small midges and insects, allowing larger bees and butterflies to act as pollinators.

The secret history of corn is revealed in its genome

A new collection of corn genomes provides a detailed understanding of the genetic diversity and adaptability of corn plants. Researchers have mapped the first corn genome in 2009 and filled in gaps since, revealing how the corn genome was shuffled over time.

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How plants leave behind their parents' genomic baggage

Researchers at Cold Spring Harbor Laboratory found a gene responsible for reinstalling beneficial epigenetic modifications in plants. This process helps prevent the transmission of harmful genetic traits to offspring, allowing plants to evolve and diversify.

Terpen-tales: The mystery behind the unique fragrance of the lovely lavender

A team of scientists from China has sequenced the genome of Lavandula angustifolia to understand the genetics behind its distinctive fragrance. The study revealed that gene duplications and terpenoid diversification led to the evolution of unique compounds, with potential applications in stress relief, skin conditioning, and pollination.

Winning gene combination takes all

Scientists have successfully identified the complete avenacin biosynthetic pathway in oats, which provides resistance to soil-borne diseases like take-all. This discovery has implications for creating disease-resistant lines of wheat using modern technologies.

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Plant gene found in insect, shields it from leaf toxins

A Chinese research team discovered that whiteflies use a plant gene to degrade common plant toxins, allowing them to feed on plants safely. The team developed a strategy to undo this superpower by creating a small RNA molecule that interferes with the whitefly's gene.