Bacterial Pathogens
Articles tagged with Bacterial Pathogens
DNA analyses uncover what is hiding under the cap plaguing the white button mushroom industry
A University of Florida study reveals that bacterial blotch in white button mushrooms is caused by a complex of multiple bacteria, not a single pathogen. The discovery could support better diagnostics and more effective, sustainable treatments, helping strengthen mushroom production nationwide.
Singapore researchers advance phage therapy in fight against antimicrobial resistance
Researchers identified how Mycobacterium abscessus evades treatment and proposed a strategy to overcome resistance, offering a pathway towards more effective treatments. A combination therapy targeting both smooth and rough variants proved more effective than single-phage treatment.
Ancient viruses serving as gene delivery couriers to help bacteria resist antibiotics
Researchers at the John Innes Centre discovered a three-gene control hub that enables bacteria to share genes linked to antibiotic resistance. The study found that this mechanism is controlled by a bacterial immune system, which has been repurposed to release gene transfer agents.
Foxes and birds could be ‘early warning system’ to survey spread of antibiotic resistance into ecosystems
Researchers discovered highly antibiotic-resistant bacteria in wildlife samples, including foxes and birds, indicating potential early warning system for AMR spread. The study highlights the need for environmental interventions to prevent resistance from reaching clinical settings.
Study: Wildlife trade raises risk of disease spread to humans
A new study by University of Maryland researcher Meredith Gore and colleagues found that traded wild mammals are 1.5 times more likely to share infectious agents with humans than species not involved in trade. The risk is higher for animals traded illegally or sold live, which fuels the demand for exotic pets.
Researchers move closer to preventing pandemics
Researchers developed an AI tool called PathogenFinder2 that can detect harmful bacteria before they infect humans. The tool uses protein language models and has been shown to significantly improve the detection of bacterial threats.
Use of controversial weedkiller inadvertently selects for drug-resistant bacteria that can spread to hospitals
Scientists have found evidence that glyphosate, a widely used weedkiller, can select for drug-resistant bacteria that can thrive in agricultural areas and then spread to hospitals. The study revealed that bacterial strains from hospital infections with extreme drug resistance showed high resistance to glyphosate and its byproducts.
Millions of protein complexes added to AlphaFold Database shed light on how proteins interact
Scientists have added millions of protein complex structures to the AlphaFold Database, shedding light on how proteins interact. The dataset prioritizes human health and disease research, enabling researchers to test, refine, and build upon it.
Ticks carrying more than one pathogen are on the rise in US Northeast
A recent study by the Cary Institute of Ecosystem Studies reveals a concerning trend of ticks carrying multiple pathogens in the US Northeast. More than 1 in 10 nymphal ticks tested positive for at least two disease-causing pathogens, with co-infection rates approaching 11% for Lyme disease and babesiosis. This increase in co-infection...
Bacterial pathogens build antibiotic-resistant “bunkers” using filament scaffolds
Researchers discovered a mechanism that enables bacterial pathogens to assemble antibiotic-resistant 3D biofilms, which protect them from antibiotics and the immune system. The team found that adhesive pili form flat sheets linking bacteria together and shield them from hostile environments.
UNIGE and NTU Singapore scientists find that silencing bacteria can worsen heart infections
Researchers found that silencing bacteria can worsen heart infections by promoting aggressive biofilm growth and reducing antibiotic effectiveness. The study highlights the need for targeted therapeutic strategies against infectious endocarditis.
1.25 million euros for research into bacterial infection mechanisms in rice
Researchers will use state-of-the-art imaging techniques and genome editing to study the mechanisms of Xanthomonas oryzae bacterial blight in rice. The goal is to gain a fundamental understanding of the infection process, which may lead to developing resistant rice varieties.
New AI model improves accuracy of food contamination detection
Researchers at Oregon State University have developed a deep learning-based model for rapid bacterial contamination detection, eliminating misclassifications of food debris. The enhanced model can reliably detect bacteria in three hours and has the potential to prevent outbreaks and protect consumer health.
Sugar molecules point to a new weapon against drug-resistant bacteria
Researchers have designed antibodies that recognize a unique sugar found on bacterial cells, providing a potential new treatment for multidrug-resistant hospital-acquired infections. The target of the antibody is pseudaminic acid, a sugar molecule produced exclusively by bacteria and used to evade immune responses.
Ancien DNA pushes back record of treponemal disease-causing bacteria by 3,000 years
Scientists have recovered a genome of Treponema pallidum from 5,500-year-old human remains in Colombia, pushing back the genetic record of this pathogenic species by over 3,000 years. The discovery sheds new light on the evolutionary history of treponemal pathogens and their occurrence in human populations.
New study shows how light suppresses virulence in antibiotic-resistant pathogen
Researchers at the University of Chicago have discovered a light-sensitive signaling cascade in Pseudomonas aeruginosa that suppresses biofilm formation and virulence. The study, published in Nature Communications, identifies a small protein called DimA as the key trigger for this process.
USF-led paper sheds light on human impact of first known ancient pandemic
The study provides direct evidence of large-scale human mortality during the Plague of Justinian and offers insight into how people moved, lived, and became vulnerable within ancient cities. The mass grave at Jerash, Jordan, helps resolve a long-standing puzzle about ancient community dynamics.
Fatal infection risk in newborns may increase when this bacteria and fungus mix
Researchers discovered that GBS interacts with C. albicans, increasing the risk of severe and fatal infections in newborns and making standard treatments less effective. The co-infection can also reduce the effectiveness of existing GBS treatments.
4 million for study with personalized phage therapy
The study will select the exact phage that is appropriate for each patient's bacteria, and aims to reduce antibiotic use and healthcare costs. Bacteriophages have been shown to be effective against resistant bacteria causing urinary tract infections.
SickKids-led study reveals promising gut-targeted therapy for C. difficile infections
A SickKids-led study reveals how bile acids can bind to block C. diff's most dangerous toxin, leading to the development of a new compound that neutralizes the toxin directly in the gut. This approach preserves gut health and targets the toxin with precision, offering hope for safer treatments.
How can nursing homes protect more patients from infections?
The new guideline recommends full-time infection prevention staff, comprehensive training, and support for all staff, as well as partnerships with hospitals and public health agencies. This guidance aims to reduce the risk of infections in nursing homes, saving lives and money.
Biomaterial vaccines to make implanted orthopedic devices safer
Researchers have developed a novel vaccine strategy using biomaterial scaffold vaccines to protect against Staphylococcus aureus infections in orthopedic device implants. The vaccines, made with immune cell-attaching molecules and S. aureus-specific antigens, create a beneficial immune response that significantly lowers bacterial burden.
New antibiotic for drug-resistant bacteria found hiding in plain sight
Researchers have discovered a promising new antibiotic, pre-methylenomycin C lactone, which is over 100 times more active than the current antibiotic methylenomycin A. This finding provides hope in the fight against antimicrobial resistance (AMR), which affects millions of people worldwide.
DNA from Napoleon’s 1812 army identifies the pathogens likely responsible for the army’s demise during their retreat from Russia
Researchers extracted DNA from Napoleon soldiers' teeth and identified Salmonella enterica and Borrelia recurrentis as causes of enteric fever and relapsing fever. The discovery sheds new light on the factors contributing to the army's downfall.
Global platform for pandemic preparedness to be established at DTU National Food Institute
The Global Pathogen Analysis Platform (GPAP) will enable low- and middle-income countries to conduct research and surveillance of infectious diseases independently. The platform aims to prevent disease outbreaks from developing into pandemics by detecting genetic sequences of potential pathogens.
Winners of Applied Microbiology International Horizon Awards 2025 announced
The winners of the Applied Microbiology International Horizon Awards 2025 have been recognized for their groundbreaking contributions to global challenges through applied microbiology. The awards celebrate excellence across various domains, including drug discovery and sustainable agriculture.
Ateneo scientists research potential anti-ulcer vaccine
Researchers from Ateneo de Manila University have identified key proteins produced by Helicobacter pylori that can trigger a strong immune response. By analyzing these proteins using immunoinformatics, the team has pinpointed potential vaccine targets to prevent stomach ulcers and cancer.
Conversion of IgG antibodies to IgM broadens antibacterial activity
Researchers at UMC Utrecht discovered that converting monoclonal antibodies from IgG to IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant bacterial pathogens. This finding could guide the future design of antibody therapies against bacterial infections.
University of Houston scientists learn that rare bacterium ‘plays dead’ to survive
Researchers at the University of Houston discovered that T. phoenicis can enter dormancy to evade detection, highlighting the resilience of spacecraft-associated microbes and raising concerns about planetary protection. The findings may lead to better detection methods and more effective sterilization strategies in various industries.
Little-known strep bacteria behind growing number of severe infections
A new study reveals rising rates of invasive SDSE infections across Australia, particularly among older Australians and those from remote regions. The research highlights disparities in health outcomes between regions and populations, emphasizing the need for improved surveillance and prevention strategies.
Special lactic acids reduce antibiotic resistance in infants
Researchers at DTU have discovered a way to combat antibiotic-resistant bacteria by nourishing special bifidobacteria that is naturally occurring in the gut. Special lactic acids produced by bifidobacteria play a key role in keeping antibiotic-resistant bacteria at bay.
Responding to the challenge of antibiotic-resistant bacteria
The IMPACT-CETR aims to develop preventive strategies against antibiotic-resistant pathogens Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. The project seeks to harness immunity in these bacteria to prevent infections and reduce the emergence of resistance.
From Miami to Berlin: a stowaway rat reveals hidden global health risks
A rat discovered on a flight from Miami to Berlin revealed hidden global health risks, including the presence of a methicillin-susceptible Staphylococcus aureus strain nearly identical to human variants. The study highlights the importance of standardized pathogen screening for animal stowaways and rats as indicators of ecosystem health.
Rice bioscientist wins NSF CAREER Award to investigate bacterial toxins, expand inclusion in STEM
Marcos de Moraes will study the molecular mechanisms and evolutionary roles of bacterial deaminase toxins, which can alter genetic material. He aims to develop tools for genome engineering and biotechnology while creating a lab environment accessible to students with disabilities.
Protecting the most vulnerable: ECDC recommendations to address the ongoing local transmission of diphtheria
Diphtheria is still being reported in Europe, with cases higher than before 2020, affecting vulnerable populations like homeless individuals, migrants, and those who use or inject drugs. ECDC recommends tailored public health response measures to protect these groups.
Pandora’s microbes – The battle for iron in the lungs
Researchers identified two natural products, pandorabactin A and B, produced by Pandoraea bacteria to complex iron. These molecules may play a role in the survival of these pathogens in iron-poor environments.
New research reveals a deadly fungal pathogen’s vulnerabilities
Scientists at the Stowers Institute and University of Georgia discover how Cryptococcus neoformans thrives, identifying over 300 potential targets for novel antifungal drugs. The study provides an atlas for developing new therapies to combat this lethal fungus.
Smithsonian research reveals that probiotics slow spread of deadly disease decimating Caribbean reefs
Researchers have discovered that a bacterial probiotic helps slow the spread of stony coral tissue loss disease (SCTLD) in already infected wild corals in Florida. Applying the probiotic treatment across entire coral colonies helped prevent tissue loss, providing a more lasting protection than traditional antibiotics.
Vigilance and targeted public health measures are essential in the face of the diphtheria epidemic that has affected vulnerable populations in Western Europe since 2022
A recent study reveals the diphtheria epidemic in Western Europe is primarily caused by contamination during migratory travel or in destination countries, not in the countries of origin. The researchers emphasize the importance of maintaining high levels of vigilance and public health support among vulnerable populations.
Revelations on the history of leprosy in the Americas
Scientists have discovered that leprosy, caused by bacteria Mycobacterium lepromatosis, has been infecting humans in the Americas for at least 1,000 years. The study analyzed DNA from ancient human remains and recent clinical cases, confirming that the disease was already widespread in North and South America before European colonization.
Using bacteria to improve microbiota resistance to pathogens
Researchers identified seven bacteria with a potential barrier effect against vancomycin-resistant enterococci. The addition of the bacterial mixture reduced the proliferation of pathogenic bacteria in mice, suggesting a promising therapeutic approach.
Study: DNA test detects three times more lung pathogens than traditional methods
A recent study found that Metagenomic next-generation sequencing (mNGS) can detect pathogens in 86% of cases, outperforming conventional microbiological tests which identified pathogens in only 67% of cases. mNGS guides treatment decisions and improves patient outcomes by detecting rare/atypical pathogens.
How cholera bacteria outsmart viruses
Researchers found that cholera bacteria acquired multiple distinct immune systems protecting them from diverse types of phages. These defense systems, including WonAB, GrwAB, and Vc SduA, contribute to the bacterial population's resistance spectrum.
The scent of death? Worms experience altered fertility and lifespan when exposed to dead counterparts
Roundworm C. elegans avoids deceased conspecifics due to olfactory cues from metabolites AMP and histidine, leading to reduced fitness and increased egg laying. The detection of these signals may be an evolutionarily maintained mechanism for detecting cellular death.
AI predicts bacterial resistance to cleaning agents
A new method using artificial intelligence and DNA decoding can predict how well disease-causing bacteria like Listeria tolerate disinfectants. The research may lead to smarter hygiene strategies and faster responses when pathogenic bacteria are present in food production.
Home washing machines fail to remove important pathogens from textiles
A new study found that many home washing machines are insufficient for decontaminating healthcare worker uniforms, allowing antibiotic-resistant bacteria to survive. The researchers propose revising laundering guidelines or using on-site industrial machines to improve patient safety.
Antibiotic resistance: Towards drugs to disarm bacteria
Researchers have discovered a protein, Mfd, that promotes bacterial resistance and spontaneous mutations. A new compound, NM102, has been developed to block this protein, reducing the bacteria's ability to develop resistance and effectively combat antibiotic-resistant strains.
UMass Amherst tick researchers identify new strain of rickettsia bacteria that causes spotted fever infections in humans
Researchers at UMass Amherst's New England Center of Excellence in Vector-borne Diseases have identified a new strain of Rickettsia bacteria that causes spotted fever infections in humans. The discovery in Maine suggests rabbit ticks could be a zoonotic vector for serious infections, contradicting the usual dog tick vector.
How bacteria use sneaky chemistry to disable plant defenses
Researchers found that pathogenic bacteria like Pseudomonas syringae produce glycosyrin, a molecule that blocks plant immune surveillance. Plants have evolved countermeasures to strip away sugars from flagellin, but this bacterial strategy disrupts these defenses and creates conditions favorable for bacterial growth.
Antibiotic-resistant E. albertii on the rise in Bangladeshi chicken shops
Researchers detected widespread contamination of retail chicken meat in Bangladesh with antibiotic-resistant E. albertii, a lesser-known but deadly pathogen. The study highlights the need for improved hygiene measures and stricter regulations to prevent foodborne infections.
New study confirms copper-based fungicides as a reliable solution for aerial stem rot in potatoes
A new study confirms copper-based fungicides as a reliable solution for aerial stem rot in potatoes. The research found that copper fungicide treatments consistently slowed disease spread and improved yields over a 10-year period.
Studies shows new class of antibiotic is effective in tackling MRSA
A new class of antibiotic has been shown to be effective in treating MRSA infections, with a daily dose of epidermicin NI01 demonstrating equal efficacy to the current standard of care. The findings justify further pre-clinical development and could lead to new gel-type therapies for skin infections.
Antibiotic resistance among key bacterial species plateaus over time
A study analyzing over 3 million bacterial samples found that antibiotic resistance initially rises but stabilizes over time, reaching an equilibrium in most species. The study suggests that continued increase in antibiotic resistance is not inevitable and provides new insights to monitor drug resistance.
New vaccine concept tackles harmful bacteria in the intestine
Researchers have developed an effective approach to tackle intestinal pathogens by administering oral vaccinations combined with harmless bacteria that starve out pathogenic microbes. This method has shown promising results in preventing colonization with salmonella and effectively tackling established E. coli bacteria.
Good and bad bacteria: What microorganisms can do in our food
The BfR conference discusses the role of microorganisms in food production, focusing on both beneficial and pathogenic properties. The event explores topics such as E. coli, Listeria monocytogenes, and the importance of food microbiology in ensuring public health.
Tuberculosis in children and adolescents: EU/EEA observes a rise in 2023
The European Centre for Disease Prevention and Control (ECDC) reports a rise in tuberculosis cases among children and adolescents in the EU/EEA, with a slight increase in the notification rate from 2.0 to 2.5 per 100,000 population. The highest proportion of paediatric TB was observed in children aged 1 to 4 years old.
Study: Tuberculosis relies on protective genes during airborne transmission
Researchers have discovered a family of genes essential for tuberculosis survival during airborne transmission, providing new drug targets. The study sheds light on the bacterium's protective mechanisms, which could prevent infection spread and treat existing cases.
White blood cells use brute force to dislodge bacteria
A recent study in Nature Communications reveals that white blood cells employ a novel mechanism to dislodge bacteria from human tissues using brute force and integrin-based adhesion rings. The research, led by Xuefeng Wang, has significant implications for understanding the role of macrophages in cleaning up environmental pollutants.
Study uncovers the core principles of low-resistance antibiotics
A groundbreaking study has identified a dual-target approach that significantly prevents the development of resistance in bacteria. This approach combines membrane disruption with an additional critical cellular pathway, offering a potential solution to mitigate the escalating threat of antimicrobial resistance.