Study reports multidrug resistant bacteria found in hospital sinks
Research reveals bacterial spread from drainpipes to patients occurs via a staged mode of transmission, with colonies growing towards sink strainers before splattering onto surfaces.
Bacterial Pathogens
Articles tagged with Bacterial Pathogens
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New paper published in Phytobiomes may lead to novel methods of Rhizoctonia solani control
Researchers identified a novel biological aspect of Rhizoctonia solani, where bacteria persistently associate with the fungus during growth on solid media. This association affects the biology of the fungal host and its interactions with plants, raising prospects for developing alternative disease management strategies.
Transplanting good bacteria to kill Staph
Researchers isolated and grew good bacteria with antimicrobial properties to treat atopic dermatitis. The treatment successfully reduced Staphylococcus aureus on the skin, offering a new approach to managing the condition.
'Smart' bacteria remodel their genes to infect our intestines
Researchers at Hebrew University of Jerusalem discovered how enteropathogenic bacteria sense host attachment and reorganize gene expression to exploit cells. This understanding may lead to new strategies to combat bacterial infections.
Personalized skin lotions keep disease-causing bacteria at bay
Researchers discovered two new antibiotics in harmless skin bacteria that effectively fought off Staphylococcus aureus, a common cause of skin infections. Personalized lotions with these friendly bacteria prevented colonization in patients with Atopic Dermatitis, offering a potential solution to frequent skin infections.
Listeria may be serious miscarriage threat early in pregnancy
Researchers found that listeria causes inflammation and collateral damage to the placenta, allowing bacteria to invade the fetus. The study suggests that listeria may be a culprit in some miscarriages without diagnosed cause. Effective antibiotics are available to treat the infection.
Seagrasses greatly reduce bacteria, benefiting humans and marine life
A new study reveals that seagrass meadows can reduce bacteria pathogenic to humans and marine life by up to 50%. The presence of seagrasses also reduces the prevalence of disease in corals located nearby, with field surveys showing a 2-fold decrease in disease compared to coral without seagrass neighbors.
New protein discovery may lead to new, natural antibiotics
Scientists have discovered a new protein that regulates gene expression and is frequently found next to antibiotic-producing gene clusters. The discovery, known as LoaP, expands the basic knowledge of processive antitermination and demonstrates its widespread presence among bacteria.
Bacterial survival strategy: Splitting into virulent and non-virulent subtypes
Researchers found that enteropathogenic E. coli (EPEC) differentiates into two sub-populations, one virulent and one non-virulent, with the virulent state maintaining long-term memory. This discovery sheds light on bacterial virulence strategies and may lead to new approaches for fighting infections.
Method to identify bacteria in blood samples works in hours instead of days
Engineers at University of California San Diego developed a desktop diagnosis tool that detects harmful bacteria in blood samples in hours. The breakthrough uses proprietary chemistry, machine learning, and high-end imaging to identify DNA sequences from bacteria causing food-borne illnesses and pneumonia.
Blue-bellied insects may play a role in the fight against citrus greening
Researchers found that hemocyanin, an oxygen-transporting protein, is highly expressed in Asian citrus psyllids infected with the bacterium causing citrus greening. The protein may signal an immune response to infection and could be harnessed to help control disease spread.
Decision-making process of viruses could lead to new antibiotic treatments
Researchers at Texas A&M AgriLife Research have found that viruses make decisions about their actions in host bacteria, similar to human decision-making. The study's findings could lead to the development of more effective phage therapy for treating bacterial diseases.
Cholera bacteria stab and poison enemies at predictable rates
Researchers used physics equations to track bacterial battles over sustenance and turf, gaining insights for new targeted therapies against infections. Cholera bacteria wield harpoon-like appendages covered in poison, with a correlation found between weaponry and cooperative social behavior.
Atomic-scale view of bacterial proteins offers path to new tuberculosis drugs
Scientists at Rockefeller University have developed a detailed analysis of RNA polymerase, crucial to all cells, which is targeted by the antibiotic rifampicin. The study identifies potential strategies for new drugs that can effectively combat resistant TB strains.
Salicylic acid promotes nasal mucosa colonization
Regular consumption of salicylic acid can promote and prolong bacterial colonization by depriving the body of iron, which is essential for bacterial growth. This study found that increased biofilm formation allows bacteria to survive longer under unfavorable conditions.
Defense mechanism employed by algae can effectively inhibit marine fouling
Researchers have developed a method to inhibit hazardous seawater fouling using cerium dioxide nanoparticles, mimicking the natural defense mechanism of algae. The particles block bacterial communication and prevent biofilm formation, making them an eco-friendly alternative to copper-based biocides.
Cytotoxins contribute to virulence of deadly epidemic bacterial infections
A new report in The American Journal of Pathology reveals that potent cytotoxins produced by group A streptococcus (GAS) contribute to the severity of 'flesh-eating disease'. Production of both NADase and streptolysin O is necessary for full virulence, and infections can be controlled better with toxin-deficient bacteria.
Feed a cold, starve a fever? Not so fast, according to Salk research
Research from the Salk Institute shows that certain bacteria, such as Salmonella Typhimurium, can block the host's appetite loss response to make themselves healthier while also promoting transmission. This discovery could have implications in treating infectious diseases and may lead to new therapies for metabolic disease.
Why Salmonella wants its host to have a healthy appetite
A study found that when a bacteria reduces its virulence by blocking loss of appetite, it increases mouse survival and helps the pathogen spread. Salmonella Typhimurium, a natural intestinal pathogen in mice, uses this strategy to replicate and transmit to other hosts.
Abnormal antibody levels in intestine may promote inflammation in people with HIV-1
A new study found that abnormal antibody production in the intestine of people with HIV-1 may lead to chronic inflammation and AIDS despite treatment. The research revealed that immune system cells in the intestines have decreased capacity to produce mature antibodies.
NIH advances understanding of defenses against antibiotic-resistant klebsiella bacteria
Researchers discover that a component of the innate immune system, the complement system, plays a crucial role in killing antibiotic-resistant ST258 bacteria. The study's findings suggest that a modified antibody could be used to develop new tools to treat and prevent infections caused by these bacteria.
Scientists decipher a mechanism in serious skin infections
Researchers have identified a key mechanism behind the aggressive progression of skin infections caused by Community-Associated MRSA strains. The discovery suggests that modifying the bacterial cell envelope could help prevent such infections.
Immune defense without collateral damage
A team of researchers from the University of Basel has clarified the role of the enzyme MPO in fighting infections. They found that MPO produces a highly aggressive acid that kills pathogens without damaging surrounding tissue, providing new approaches for immunity strengthening therapies.
Team discovers how bacteria exploit a chink in the body's armor
Researchers have found that Staphylococcus aureus uses a unique enzyme called superoxide dismutase to resist nutritional immunity and cause disease. This discovery could lead to the development of new antibacterial therapies to combat antibiotic-resistant infections.
Moth gut bacterium defends its host by making antibiotic
Researchers discovered that a specific bacterial species in moth gut microbes produces an antimicrobial peptide called mundticin KS, which defends its host against pathogens and promotes symbiosis. This finding has implications for agriculture and health, potentially leading to new biocontrol strategies and novel antibiotics.
Bodyguards in the gut have a chemical weapon
Beneficial bacteria in the gut of moth larvae produce an antimicrobial agent that kills competing bacteria. The symbionts ensure a healthy gut flora and reduce infection risk, making them a potential tool for controlling agricultural pests.
Time to put TB on a diet!
Researchers discovered that Mycobacterium tuberculosis reprograms infected cells to feed on lipids and membranes, leading to new treatment opportunities. The study provides a promising lead in tackling the disease by starving the bacterium of its preferred high-fat food source.
Molecule shows ability to thwart pathogens' genetic resistance to antibiotic
Researchers at Oregon State University have developed a molecule that neutralizes bacteria's genetic resistance to antibiotics. The PPMO molecule restores the effectiveness of an ultra-broad-spectrum drug, meropenem, against three different genera of bacteria with NDM-1 enzyme.
Why hospital antibiotic management strategies do little to curb resistance
A new study reveals that hospital antibiotic management strategies, including cycling and mixing, are ineffective in combating antibiotic resistance. The researchers recommend alternative strategies like reactive cycling and individualized treatments to optimize antibiotic use.
Biophysics plays key role in immune system signaling and response
Researchers discovered that biophysical cues of pathogen-associated molecular patterns (PAMPs) influence the immune system's response to pathogens. The findings suggest that understanding these cues can help fine-tune vaccine responses and generate potent immune reactions.
Manipulating signals in bacteria could reduce illnesses
Researchers at University of Illinois Chicago are studying bacterial chemical signals to manipulate sickness-causing microorganisms into a nonhostile state. By understanding the molecular mechanisms of these signals, scientists aim to develop new alternatives to antibiotics that fight bacterial infections.
UTSW scientists identify protein central to immune response against tuberculosis bacteria
Researchers have identified a protein called Smurf1 that plays a crucial role in the immune system's ability to recognize and destroy tuberculosis bacteria. This discovery could lead to the development of new treatments by strengthening this immune pathway.
WPI researcher wins NSF CAREER Award to study how bacteria survive in stressful conditions
Dr. Scarlett Shell is awarded a $1.1 million NSF CAREER Award to investigate the molecular mechanisms of bacteria's stress response, which could lead to new treatments for infectious diseases like tuberculosis. Her work aims to enrich educational experiences for students and inspire careers in science.
Bacterial Pac Man molecule snaps at sugar
Researchers discovered a bacterial protein that uses a Pac Man-like chewing motion to grab and hold onto sugar molecules, allowing pathogens to evade the immune system. This understanding could lead to the development of new therapeutics targeting this protein.
Researchers discover new mechanism for Type IV pili retraction in Vibrio cholerae
A new study reveals that a minor pilin protein triggers pilus retraction in Vibrio cholerae, differing from other disease-causing bacteria. This discovery advances understanding of Type IV pili function and may aid in developing prevention and treatment strategies for cholera.
Scientists develop new antibiotic for gonorrhea
Scientists at the University of York have developed a new antibiotic for gonorrhoea by harnessing the therapeutic effects of carbon monoxide-releasing molecules. The treatment targets the bacteria's energy production, preventing it from respiring oxygen and ultimately leading to its death.
NIH-supported scientists accelerate immune response to tuberculosis in mice
Researchers at Washington University in St. Louis accelerate immune response to tuberculosis in mice by activating dendritic cells, leading to near-sterilizing immunity levels. The study could lead to improved TB vaccines for humans, addressing the variable protection provided by current BCG vaccine.
Researchers reveal the secret code language of bacteria
Bacteria have been found to use a code language consisting of cryptic palindromes to determine whether to enter a dormant state or be interrupted by antibiotics. This discovery may help develop new antibiotics by understanding the code language used by pathogenic bacteria.
The evolutionary secret of H. pylori to survive in the stomach
The study identifies a new nickel transporter crucial for the pathogen's ability to colonize the stomach and survive its acidic environment. The discovery sheds light on the genetic modifications that enabled H. pylori to adapt to this hostile environment, highlighting the importance of metals in bacterial pathogenesis.
UTSW study identifies a way to prevent burn injury infection -- without antibiotics
A new approach to prevent burn injury infections was developed by UTSW researchers, which targets the bacteria's ability to bind to host cells rather than killing them. The method, using an engineered adhesion inhibitor molecule, substantially decreased bacterial levels and prevented infection for three days.
DNA markers distinguish between harmless, deadly bacteria
A large genome study has identified potential virulence factors to discriminate new Francisella species from the deadly F. tularensis bacterium. The study provides a framework for identifying new isolates and environmental detections, improving disease diagnosis and bioweapon detection.
New diagnostic test kit offers easy identification of virulent pathogens in remote locations
A new battery-powered detection system can identify 16 virulent pathogens with high sensitivity and provides positive identification from as few as 10 DNA sequences. The device is designed for use in remote locations where laboratory resources are lacking, addressing the lack of timely diagnosis and effective treatment.
Researchers add to evidence that common bacterial cause of gum disease may drive rheumatoid arthritis
Researchers found a common bacterial cause of gum disease may trigger rheumatoid arthritis by inducing hypercitrullination, leading to inflammation and tissue damage. A study published in Science Translational Medicine identified Aggregatibacter actinomycetemcomitans as the primary pathogen responsible for this process.
Drugs from nature: Big effects of multiple compounds in small amounts
Researchers at Goethe University Frankfurt have discovered a class of peptides that can kill insect larvae, producing up to four times more compounds than previously thought possible. The peptides, known as rhabdopeptide/xenortide peptides (RXPs), are produced by bacteria and play a crucial role in infection.
Leibniz Prize awarded to RNA researcher Jörg Vogel
Jörg Vogel, a leading RNA researcher, has been awarded the €2.5m Leibniz Prize for his seminal contribution to understanding regulatory RNA molecules in infection biology. His research could lead to new ways to fight pathogens.
How miniature predators get their favorite soil bacteria
Tiny soil predators called protists 'eavesdrop' on bacteria's communication using scent, helping them choose the best prey. The discovery could lead to practical applications in biological pest control and agricultural research.
Protein disrupts infectious biofilms
A team of researchers at Caltech and the University of Oxford identified a protein that degrades and inhibits biofilms of Pseudomonas aeruginosa, the primary pathogen in cystic fibrosis infections. This discovery offers a new approach to inhibit biofilm development and has promise for treating antibiotic-resistant biofilm infections.
Miraculous proliferation
Recent experiments by Loessner and his group have shown that L-forms are an independent form of life that can multiply indefinitely. They form a crazy network of vesicles with elastic connector tubes, enabling them to exchange cytoplasm and multiply without cell walls or genetic material.
'Pulling' bacteria out of blood
Scientists at Swiss Federal Laboratories for Materials Science and Technology (EMPA) are working on a novel treatment approach for blood poisoning. They aim to remove bacteria from the blood using magnetic purification, which could potentially replace antibiotics in some cases.
Unique strain of lactic acid bacteria in Buryat milk is found
Researchers from Lomonosov Moscow State University have isolated a unique strain of lactic acid bacteria, Lactococcus lactis subsp. lactis 194, from Buryat milk that possesses a wide range of antimicrobial action against Gram-positive and Gram-negative bacteria. The strain also shows antifungal properties, making it a promising candida...
Bacteria produce aphrodisiac that sets off protozoan mating swarm
Researchers at UC Berkeley discovered a bacterium, Vibrio fischeri, releases an enzyme that induces choanoflagellates into full mating frenzy. This finding suggests bacteria may influence animal mating.
New compound targets TB bacterium's defense against the immune system
Researchers at Brown University have developed a new compound that can render Mycobacterium tuberculosis susceptible to the immune system. The compound inhibits the bacterial proteasome, making proteins damaged by nitric oxide accumulate and cause bacteria death.
Melbourne scientists publish evidence for world-first therapeutic dental vaccine
A Melbourne-based team has developed a vaccine for chronic periodontitis, aiming to reduce the need for surgery and antibiotics. The vaccine targets enzymes produced by a specific bacterium, triggering an immune response that neutralizes its toxins.
Mechanism of probiotic health promotion revealed
New research reveals the mechanism by which probiotic Lactobacillus paracasei DG promotes health. The probiotic releases a novel polysaccharide that stimulates the immune system to release anti-inflammatory chemicals.
Research team discovers a pathogen's motility triggers immune response
A research team at the University of Georgia has discovered that a pathogen's ability to move through the body triggers an immune response. The study found that bacterial motility induces the formation of neutrophil extracellular traps, which are web-like structures of DNA associated with antimicrobial molecules.
Genomics technique could accelerate detection of foodborne bacterial outbreaks
A new metagenomics methodology can quickly diagnose foodborne bacterial outbreaks by analyzing DNA sequencing data. This approach identified Salmonella pathogen variants and detected co-infections with Staphylococcus aureus, revolutionizing disease surveillance.
Pitt civil engineering research going viral with bacteriophages
Researchers at the University of Pittsburgh are using cross-assembly phage (crAssphage) as an indicator of fecal contamination in water, which can help prevent disease outbreaks and improve public safety. The study aims to establish a correlation between crAssphage presence and pathogens in irrigation water.
Staph uses nitric oxide enzyme to colonize noses
Researchers discovered that Staph bacteria use the nitric oxide synthase enzyme to colonize nasal passages, allowing them to thrive in low-oxygen environments. This mechanism may contribute to the virulence and resistance of staphylococcus bacteria, making it a potential target for prevention strategies.
Nano factories to prevent bacterial colonization
Researchers at the University of Konstanz are developing nano factories that can prevent bacterial colonization on surfaces. The team, led by Sebastian Polarz and David Schleheck, plans to create a cocktail of chemical compounds that specifically target bacteria, reducing the need for antibiotics.
Just add water: New discovery in plant-disease mechanism
A new study by Michigan State University scientists reveals that certain virulent bacteria can directly inject a protein into plant cells, increasing water content and disease prevalence. This discovery highlights the critical role of humidity in plant-disease outbreaks, particularly under conditions of prolonged high humidity.