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What cures you may also ail you: Antibiotics, your gut and you

A new study finds that antibiotics like ciprofloxacin significantly affect the diversity and abundance of health-associated bacteria in the human gut. The study reveals that even after treatment is stopped, some strains of beneficial bacteria may take up to four weeks or longer to return to pre-treatment levels.

SourcePLOS·JournalPLOS Biology·DateNov 17, 2008

New antibiotic beats superbugs at their own game

Researchers at Rockefeller University tested Ceftobiprole against multidrug-resistant Staphylococcus aureus (MRSA) bacteria, achieving a 100% kill rate. The new antibiotic successfully targeted the gene that confers resistance, offering hope in combating staphylococcal infections worldwide.

SourceRockefeller University·JournalAntimicrobial Agents and Chemotherapy·DateJul 2, 2008

Researchers track Lyme disease spirochetes

Microbiologists track B. burgdorferi movement and interaction with vascular walls in mice to understand dissemination mechanisms, shedding light on disease processes. Real-time imaging provides critical insight into the complex process of spirochete spread.

SourcePLOS·JournalPLOS Pathogens·DateJun 19, 2008

Novel compound may treat acute diarrhea

Scientists have discovered a novel compound that targets acute secretory diarrhea caused by E. coli and other enterotoxigenic strains of bacteria, reducing fluid secretion without apparent toxicity. The compound could be an inexpensive, easy-to-take treatment for debilitating illnesses leading to child deaths in developing countries.

SourceUniversity of Texas Health Science Center at Houston·JournalProceedings of the National Academy of Sciences·DateJun 16, 2008

Green tea helps beat superbugs

Egyptian scientists have discovered that green tea boosts the effectiveness of antibiotics against superbugs by up to 99.99%, increasing the killing power of chloramphenicol and making 20% of drug-resistant bacteria susceptible to cephalosporin antibiotics.

Math model identifies key to controlling epidemic

A new mathematical model has identified minimizing antibiotic treatment duration as the optimal strategy for controlling hospital-borne antibiotic-resistant bacteria epidemics. By starting treatments early and administering drugs for shorter periods, the risk of cross-infection by resistant bacteria can be significantly reduced.

Probiotics affect metabolism, says new study

A new study published in Molecular Systems Biology reveals that probiotics can significantly alter the biochemistry of gut microbes and affect metabolism. Researchers found that different probiotic strains triggered distinct biochemical changes, including modifications to bile acid metabolism, which could influence fat absorption.

SourceImperial College London·JournalMolecular Systems Biology·DateJan 15, 2008

Sexually-active gay men vulnerable to new, highly infectious bacteria

A new strain of MRSA bacteria has been discovered in sexually active gay men, showing a high rate of transmission through intimate contact and skin-to-skin contact. The study found that these men are 13 times more likely to be infected than the general population, highlighting the need for increased awareness and prevention measures.

SourceUniversity of California - San Francisco·JournalAnnals of Internal Medicine·DateJan 14, 2008

Winemaking waste proves effective against disease-causing bacteria in early studies

Researchers discover polyphenols in winemaking waste inhibit the ability of bacteria to cause cavities and form biofilms, potentially leading to new treatments for oral diseases. The findings also suggest the compounds may hold clues for lessening the ability of bacteria to cause life-threatening infections.

SourceUniversity of Rochester Medical Center·JournalJournal of Agricultural and Food Chemistry·DateJan 2, 2008

Arming the fight against resistant bacteria

Researchers at University of Wisconsin-Madison have devised a method to tackle antibiotic resistance, identifying four promising new compounds with preliminary antibacterial activity. The compounds show promise against MRSA and other Gram-positive bacteria, but further research is needed to understand their mechanism of action.

SourceUniversity of Wisconsin-Madison·JournalChemistry & Biology·DateApr 27, 2007

MRSA vaccine shows promise in mouse study

Researchers at the University of Chicago have developed a vaccine that protects mice against multiple, drug-resistant strains of Staphylococcus aureus. The combined vaccine, based on four bacterial surface proteins, provided significant protection against five virulent strains and reduced bacterial load to undetectable levels.

SourceUniversity of Chicago Medical Center·JournalProceedings of the National Academy of Sciences·DateOct 30, 2006

Researchers reveal mystery of bacterial magnetism

Researchers discovered that magnetotaxis, a phenomenon where bacteria align like tiny swimming compass needles, helps them detect lower oxygen concentrations more efficiently. This subtle advantage allows the bacteria to thrive in environments with limited oxygen, making their magnetic properties beneficial in nature.

SourceNaval Research Laboratory·JournalBiophysical Journal·DateOct 20, 2006

Killing resistant germs

Researchers have successfully synthesized platensimycin, a new antibiotic that inhibits bacterial fatty acid biosynthesis and paralyzes Gram-positive bacterial strains. This breakthrough offers hope against multiresistant bacteria, including Staphylococcus aureus and Enterococcus faecium.

SourceWiley·DateOct 12, 2006

'Good' bacteria could save patients from infection infection by deadlier ones

A new approach to fighting MRSA infections suggests allowing harmless bacteria to live in hospitals, creating a natural protection against more virulent strains. By doing so, antibiotic-free hospitals with 'good' bacteria can test the effectiveness of this method, potentially reducing the spread of deadly MRSA.

SourceThe Hebrew University of Jerusalem·JournalAnnals of The Royal College of Surgeons of England·DateNov 2, 2005

Bacteria feed on smelly breath (and feet)

A recent study published in Environmental Microbiology found methylotrophic bacteria present in the mouths of healthy volunteers and those with gum disease, but no association between bacterial levels and bad breath. The discovery may lead to a natural way of reducing smelly breath and feet.

SourceBlackwell Publishing Ltd.·JournalEnvironmental Microbiology·DateJul 26, 2005

Time to rewrite the species rulebook, MSU scientists say

Researchers at Michigan State University have found significant differences in genetic libraries among bacteria strains previously thought to be similar. The study suggests that current definitions may need revision as many bacteria share as few as 65% of their genes, highlighting the importance of ecological distinctiveness.

SourceMichigan State University·JournalProceedings of the National Academy of Sciences·DateFeb 8, 2005

Gene sequencing explains bioremediation 'bug'

Dehalococcoides bacteria can adapt to various environmental conditions through the use of mobile genetic elements, allowing them to degrade chlorinated pollutants. The genome sequence of Strain 195 reveals its ability to turn genes on and off in response to environmental cues.

SourceCornell University·JournalScience·DateJan 6, 2005

Listeria can persist in stores and processing plants

A study by Cornell University researchers found Listeria bacteria on foods in 47 out of 50 retail food stores, with 34% showing persistent strains after re-inspection. The bacteria were also found in seven food-processing plants, highlighting the need for improved control measures to prevent food contamination.

SourceCornell University·JournalJournal of Food Protection·DateJul 15, 2004