Articles tagged with Bacterial Strains
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Researchers at Rockefeller University tested Ceftobiprole against multidrug-resistant Staphylococcus aureus (MRSA) bacteria, achieving a 100% kill rate. The new antibiotic successfully targeted the gene that confers resistance, offering hope in combating staphylococcal infections worldwide.
Microbiologists track B. burgdorferi movement and interaction with vascular walls in mice to understand dissemination mechanisms, shedding light on disease processes. Real-time imaging provides critical insight into the complex process of spirochete spread.
Scientists have discovered a novel compound that targets acute secretory diarrhea caused by E. coli and other enterotoxigenic strains of bacteria, reducing fluid secretion without apparent toxicity. The compound could be an inexpensive, easy-to-take treatment for debilitating illnesses leading to child deaths in developing countries.
Researchers found that lactic acid bacteria in Feta cheese can kill off dangerous food-poisoning bacteria like Listeria. The unique taste of local cheeses is mainly due to the enterococcal bacteria they contain, which have natural anti-bacterial properties.
Egyptian scientists have discovered that green tea boosts the effectiveness of antibiotics against superbugs by up to 99.99%, increasing the killing power of chloramphenicol and making 20% of drug-resistant bacteria susceptible to cephalosporin antibiotics.
Researchers found that Staph aureus produces lactic acid in the presence of nitric oxide, allowing it to thrive. This mechanism makes it difficult for our bodies to defend against the bacteria, making traditional antibiotics less effective.
Scientists at MIT have discovered a new type of antibiotic produced by Rhodococcus bacteria in response to a competing strain. The antibiotic, rhodostreptomycin, shows promise in treating Helicobacter pylori-caused stomach ulcers.
A new mathematical model has identified minimizing antibiotic treatment duration as the optimal strategy for controlling hospital-borne antibiotic-resistant bacteria epidemics. By starting treatments early and administering drugs for shorter periods, the risk of cross-infection by resistant bacteria can be significantly reduced.
Recent studies from NIH scientists resolve debate about CA-MRSA molecular evolution, revealing a single strain USA300 as the primary cause of community-associated methicillin-resistant Staphylococcus aureus infections. The research also sheds light on how MRSA evades the human immune system and spreads rapidly.
A new study published in Molecular Systems Biology reveals that probiotics can significantly alter the biochemistry of gut microbes and affect metabolism. Researchers found that different probiotic strains triggered distinct biochemical changes, including modifications to bile acid metabolism, which could influence fat absorption.
A new strain of MRSA bacteria has been discovered in sexually active gay men, showing a high rate of transmission through intimate contact and skin-to-skin contact. The study found that these men are 13 times more likely to be infected than the general population, highlighting the need for increased awareness and prevention measures.
Researchers discover polyphenols in winemaking waste inhibit the ability of bacteria to cause cavities and form biofilms, potentially leading to new treatments for oral diseases. The findings also suggest the compounds may hold clues for lessening the ability of bacteria to cause life-threatening infections.
A new study found that benzethonium chloride is more effective in killing methicillin-resistant Staphylococcus aureus (MRSA) bacteria than other antibacterial products. The compound kills common types of non-hospital MRSA bacteria better than others, with a genuine bactericidal effect against all four tested strains.
Researchers found that bacteria carrying Shiga toxin have an evolutionary advantage against bacterial predators when co-cultured with Tetrahymena. The Shiga toxin kills Tetrahymena by binding to its surface receptor, and removing this receptor can prevent killing.
A new molecular method can identify multidrug-resistant strains of Acinetobacter baumannii in four hours, allowing for prompt isolation and infection control measures. This rapid test has the potential to reduce transmission and improve patient management.
Researchers at Tufts University discovered that the CodY protein regulates the genes controlling C. difficile toxin production, which kills human intestinal cells by causing them to burst open. This understanding opens the door for developing a drug that can prevent hospital patients from falling ill.
MIT and BU researchers develop modular system to design phages targeting specific bacterial biofilms, achieving high success rates. The technology has potential applications in treating infections and cleaning products.
Cornell researchers partner with Gene Network Sciences to create computer models of Dehalococcoides ethenogenes, a key player in cleaning toxic waste. The team aims to improve conditions for the bacteria, which sometimes struggle at cleanup sites.
Oxygen restriction increases Listeria's infective potential by allowing it to smooth its path through the gut and liver, increasing the risk of infection.
Researchers at University of Wisconsin-Madison have devised a method to tackle antibiotic resistance, identifying four promising new compounds with preliminary antibacterial activity. The compounds show promise against MRSA and other Gram-positive bacteria, but further research is needed to understand their mechanism of action.
Researchers at Duke University Medical Center found that forskolin flushes out hiding colonies of bacteria in the bladder, making them susceptible to antibiotic treatment. The study shows great promise for a new approach to treating recurring urinary tract infections.
A new lab-on-a-chip technology can identify bacterial strains causing drug-resistant pneumonia in hours, cutting down the wait from days to hours. The technology also helps in developing new drugs and can test the efficacy of existing drugs on unknown strains.
A new Staphylococcus aureus vaccine has been developed by combining four proteins that generated the strongest immune response in mice, providing significant protection against various strains of the bacterium. The vaccine showed complete protection when tested against a human strain of S. aureus.
Researchers at the University of Chicago have developed a vaccine that protects mice against multiple, drug-resistant strains of Staphylococcus aureus. The combined vaccine, based on four bacterial surface proteins, provided significant protection against five virulent strains and reduced bacterial load to undetectable levels.
Researchers discovered that magnetotaxis, a phenomenon where bacteria align like tiny swimming compass needles, helps them detect lower oxygen concentrations more efficiently. This subtle advantage allows the bacteria to thrive in environments with limited oxygen, making their magnetic properties beneficial in nature.
Researchers have successfully synthesized platensimycin, a new antibiotic that inhibits bacterial fatty acid biosynthesis and paralyzes Gram-positive bacterial strains. This breakthrough offers hope against multiresistant bacteria, including Staphylococcus aureus and Enterococcus faecium.
Researchers at UGA have discovered a species-specific cell-wall carbohydrate in B. anthracis, making it an important target for diagnostic tests and potential vaccine additives. The molecule's unique structure could help develop new vaccines and diagnostics to combat anthrax.
A team of researchers led by Emanuel Hanski discovered a protein called SilCR that blocks the immune system's distress calls, making Group A Streptococcus bacteria more virulent. The findings could lead to new strategies for treating necrotizing fasciitis and halting its rapid destruction of tissue.
Researchers found that Yersinia bacteria harbor a protein called YpkA, which mimics an enzyme and blocks the host cell's ability to change shape and move. This discovery sheds new light on the factors that make Yersinia a deadly disease-causing agent.
Oregon researchers used germ-free zebrafish to study how gut bacteria influence development. They found that specific bacterial components can restore normal enzyme levels and regulate sugar expression on intestinal cells. These findings could lead to better treatments for diseases like inflammatory bowel disease.
A new method for identifying bacteria uses genetically engineered phages that infect target bacteria, releasing biotin-capped phage progeny attached to quantum dots. The resulting phage-quantum dot complexes can be detected and counted using microscopy or spectroscopy, allowing for rapid identification of bacteria.
A special strain of soil bacterium Pseudomonas putida converts polystyrene foam into a biodegradable plastic called PHA, which can be used in medicine and disposable items. The process might also be used to convert other types of discarded plastics into PHA, reducing plastic waste.
Researchers successfully synthesized a novel vancomycin analogue with enhanced binding ability, showing promise in treating vancomycin-resistant infections. The new compound could potentially lead to the development of more effective antibiotics against these resistant strains.
A recent study found nearly one-third of the US population is colonized with staph bacteria, with a significant increase in drug-resistant superbugs. The prevalence was highest among males and children between 6-11 years old, with MRSA affecting 0.8% of participants.
Researchers have discovered a factor that enables V. cholerae bacteria to attach to intestinal cells, leading to colonization and disease. A new therapy approach is being developed based on this finding, which could improve vaccine efficacy.
Researchers at Queen's University have identified a protein that enables E. coli 0157:H7 to obtain iron, a catalyst for bacterial growth. This breakthrough discovery opens the door for studying heme iron and potentially developing therapeutics to isolate and inhibit the protein.
Researchers have discovered several new bacterial species associated with bacterial vaginosis (BV), a common infection in women. The study, published in the New England Journal of Medicine, could lead to improved detection and treatment methods.
A new approach to fighting MRSA infections suggests allowing harmless bacteria to live in hospitals, creating a natural protection against more virulent strains. By doing so, antibiotic-free hospitals with 'good' bacteria can test the effectiveness of this method, potentially reducing the spread of deadly MRSA.
Community-acquired methicillin-resistant S. aureus (MRSA) strains have been found to evade the human immune system, leading to more severe infections in otherwise healthy individuals. The study identified specific genes that may control the bacteria's ability to escape neutrophil destruction.
A new combination of analytical chemistry and mathematical data analysis techniques allows rapid identification of Coxiella burnetii, a potential bioterrorism agent causing Q fever. The method is 95.2% accurate and delivers results in 5 minutes compared to 2 hours for current detection methods.
New research reveals that rifamycin antibiotics work by removing a crucial magnesium ion from bacterial RNA polymerase, rendering the bacteria non-functional. The study's findings may lead to improved versions of these antibiotics to combat existing resistant strains.
A recent study published in Environmental Microbiology found methylotrophic bacteria present in the mouths of healthy volunteers and those with gum disease, but no association between bacterial levels and bad breath. The discovery may lead to a natural way of reducing smelly breath and feet.
Researchers found M. catarrhalis responsible for 10% of COPD exacerbations, with potential to develop vaccines to prevent infections in patients. The study involved 104 adults with COPD and identified 120 episodes of M. catarrhalis infections associated with flare-ups.
Researchers discovered a virus-like bacteriophage inserted into genetic material of hyperinvasive N. meningitidis strains, making them more likely to cause disease. The stowaway may help bacteria enter bloodstream, disrupting immune response.
Kao's research uses DNA microarrays to measure gene expression and identify a mutation that increases the production of erythromycin by five days. By recreating this mutation, she aims to develop new antibiotic-producing bacteria, revolutionizing the field of antibiotic synthesis.
Researchers investigated how reduced gravity affects bacteria, finding that certain species may thrive in space station environments. The study suggests that microgravity, combined with radiation resistance and low nutrient conditions, contributes to the success of water system bacteria.
Researchers at Michigan State University have found significant differences in genetic libraries among bacteria strains previously thought to be similar. The study suggests that current definitions may need revision as many bacteria share as few as 65% of their genes, highlighting the importance of ecological distinctiveness.
Dehalococcoides bacteria can adapt to various environmental conditions through the use of mobile genetic elements, allowing them to degrade chlorinated pollutants. The genome sequence of Strain 195 reveals its ability to turn genes on and off in response to environmental cues.
Researchers investigated anaerobic and facultative anaerobic bacteria in a study on photodynamic therapy. The photosensitizers were able to completely suppress the anaerobic key pathogens, but facultative anaerobic bacteria tested responded less effectively to PDT.
A study found that 10% of college football players had MRSA skin infections, with cosmetic body shaving increasing the risk by 43%. The researchers recommend discontinuing body shaving to decrease infection risk. Proper disinfection of whirlpools and antibacterial soap dispensers in showers can also help control MRSA spread.
The Infectious Diseases Society of America states that endocarditis and meningitis are better treated with bactericidal drugs, while urinary tract infections can be effectively managed with bacteriostatic drugs. Corticosteroids are recommended for bacterial meningitis to prevent inflammation.
A new study by the European Union shows that group A streptococci (GAS) infections are more common than previously thought, with an estimated 18-20,000 cases per year across the EU. The study also reveals a higher number of different bacterial types, with nearly 200 types currently identified, and potential antibiotic resistance issues.
A study by Cornell University researchers found Listeria bacteria on foods in 47 out of 50 retail food stores, with 34% showing persistent strains after re-inspection. The bacteria were also found in seven food-processing plants, highlighting the need for improved control measures to prevent food contamination.
A study led by Russell G. Postier found that tigecycline produced a 74 percent cure rate for hospitalized patients with complicated skin and skin structure infections (cSSSI), demonstrating promising efficacy against a wide spectrum of bacteria. The antibiotic's safety profile was also acceptable.
A new strain of Salmonella enterica serotype choleraesuis has been isolated that is resistant to all commonly used antimicrobials, including ceftriaxone and ciprofloxacin. Constant surveillance is needed to prevent further spread of this multidrug-resistant bacterium.
Researchers have successfully engineered plant-dwelling bacteria to break down toxic pollutants, enabling plants to thrive in contaminated environments. The technique uses naturally occurring bacteria and natural gene-transfer methods, offering a promising solution for environmental cleanup.
The study reveals that people from different regions carry distinct strains of the tuberculosis bacteria, indicating sociological interactions play a key role in transmission. This finding has significant implications for vaccine development, potentially leading to region-specific vaccines.
A study found that 70% of intensive care patients were colonized with bacteria from other patients in the unit. The researchers identified multiple strains of Staphylococcus bacteria that were resistant to various antibiotics, highlighting the need for improved infection control and antibiotic use guidelines.
Researchers from the Smithsonian Tropical Research Institute are using a $5 million grant to study Wolbachia, a bacterium that affects insect reproduction and evolution. The team will collect insects in Panama and use molecular tools to identify Wolbachia strains and understand their effects on host organisms.
Researchers discovered that soybean plants penalize rhizobia that don't fix nitrogen by decreasing oxygen supply, favoring cooperation and evolution of beneficial strains. This mechanism helps maintain ancient symbiotic relationships between legumes and soil bacteria.