Articles tagged with Microbial Genetics
A new gene catalog of ocean microbes has revealed nutrient limitation as a central driver in the evolution of their genomes. The study found that microbial genomes change drastically with depth, adapting to varying levels of nitrogen availability.
A new study reveals that amplicon sequencing is more robust than shotgun sequencing in discovering microbial biodiversity, with 27% more families identified. The research has significant repercussions for future analyses of microbial diversity.
Researchers have sequenced genomes of microorganisms in Aarhus Bay's subsurface seabed, showing they grow in slow motion with generation times up to 100 years. The extreme environment leads to low adaptability and minimal energy availability.
A research team has discovered that soil microbial diversity is lower than previously estimated due to the presence of relic DNA. However, thousands of species of microbes still exist in one gram of soil, making it comparable to a 'poor man's rainforest'.
Scientists have untangled the genetic material of Kansas soil, reconstructing portions of 129 microbial genomes. The study provides a leap forward in understanding the diversity and interactions of microbes in complex soil samples.
A Harvard study monitors subway microbes to identify early warning systems for public health threats. The research found that surface type and human interaction significantly influence microbial community structure, with skin- and oral-associated microbes prevalent on poles and seats.
Researchers used microbial metagenome analysis and environmental chemistry to find the most likely transit route Hannibal's forces took across the Alps, pinpointing the Col de Traversette pass as a key crossing point. The study, published in Archaeometry, provides solid evidence for Hannibal's route, dating back to 218 BC.
The US Department of Energy is awarding $13.5 million to improve sorghum's productivity under resource-limited conditions. This project will lead to strategies to increase plant biomass and more water-efficient sorghum crop systems, benefiting the rural economy and advancing a carbon-neutral energy market.
A national effort is proposed to understand and harness the capabilities of Earth's microbial ecosystems. The Unified Microbiome Initiative aims to decipher how microbes interact with each other, their hosts and environment, leading to new antibiotics, obesity-fighting methods, drought-resistant crops and next-gen biofuels.
Researchers have collected over 1,500 genetic samples from various ethnic groups to study the genome of the Volga Tatar people. The findings could lead to more effective treatments by identifying genetic markers for diseases.
Researchers have engineered a microbe called Clostridium thermocellum to produce up to 6 grams of isobutanol per liter, a significant improvement over previous results. This breakthrough could lead to more efficient biofuels production and overcome the challenges of recalcitrance in plant biomass.
Researchers found that gut microbes in mice exhibit a daily cycle, influencing circadian clock genes and metabolism. High-fat diets disrupt this cycle, leading to weight gain in mice.
Researchers at Rice University are developing gas-releasing microbial sensors to study microbe-driven processes that regulate Earth's environment. The sensors will allow researchers to test hypotheses about how microbes control environmental processes and build model ecosystems in the lab.
Researchers found that individual microbial communities are surprisingly unique and can be used to identify people over time. The study suggests that these microbiome 'fingerprints' could potentially expose sensitive information, but also offer new insights into human health and ecology.
The study analyzed microbial activities in Alaskan soils, revealing diverse species and genes involved in degrading organic carbon and producing greenhouse gases. Researchers also found evidence of previously undescribed microbes and insights into microbial survival strategies in permafrost.
The Vilcek Foundation has awarded Peter Walter the $100,000 Vilcek Prize in Biomedical Science for his pioneering work on protein transport and stress response. Sun Hur and Rob Knight also received $50,000 Creative Promise Prizes for their innovative research on enzyme reactions and microbial communities.
Joint Bioenergy Institute researchers improve isopentenol tolerance and production in E.coli, a key step towards cost-effective microbial biofuel production. The study identifies two genes, MetR and MdlB, that improve isopentenol production by 55% and 12%, respectively.
Researchers use electrostatic force microscopy to visualize charge propagation in Geobacter's protein filaments, demonstrating metallic-like conductivity. The discovery has important environmental and practical implications for energy conversion and production.
Researchers at Duke University discovered that the host determines which genes are open in the gut, while microbes regulate their usage, indicating a cooperative environment where both parties interact to thrive. This study has significant implications for understanding the intricate relationships between hosts and microbiomes.
A new study in the Journal of Clinical Investigation identifies a specific gene expression profile and microbial community associated with Crohn's disease. Pediatric Crohn's disease patients exhibit altered expression of genes DUOX2 and APOA1, as well as a distinct microbial community.
A new approach enables researchers to distinguish between different microbial species in complex communities, allowing for the discovery of previously unknown species and a better understanding of their genomic content. This breakthrough has significant implications for studying the human microbiome and its impact on individual health.
Researchers have developed a simple yet elegant solution to analyze large amounts of soil DNA data, reducing computational requirements by up to 200-fold. This breakthrough enables scientists to extract more science from the noise, paving the way for new discoveries in fields like agriculture and carbon cycling.
African sleeping sickness is caused by single-celled parasites that mate and swap genes through a process known as sexual reproduction. This study reveals sex to be a regular part of the trypanosome life cycle, enabling new combinations of genes that could lead to disease-causing strains.
Deep Carbon Observatory scientists have discovered a method to produce hydrogen more quickly and efficiently than natural processes. The new formula uses aluminum oxide, water, and olivine under high pressure, accelerating the production of hydrogen by 7-50 times.
A team of researchers from Berkeley Lab and the Scripps Research Institute used a new technique to study the role of MutS in DNA's mismatch repair system, providing new insight into genome integrity. The study validated the 'beads-on-a-string' model of DNA repair and revealed details about MutS that could be valuable for drug design an...
Researchers at the University of New South Wales discovered the genetic secrets of Antarctic extremophiles that can thrive in extremely cold and salty water. The study found that these microorganisms engage in extensive DNA swapping, enabling them to coexist despite their vastly different niches.
Researchers collected water samples up to six kilometres below the surface of the Southern Ocean, finding that physical transport in the ocean on currents shapes microbial communities. The study shows that communities connected by ocean currents are more similar to each other, regardless of distance.
A study by researchers at Arizona State University found that global warming may affect the survival of key microbe species in topsoil crusts. The team discovered that two cyanobacteria, Microcoleus vaginatus and Microcoleus steenstrupii, have split their territory between themselves due to temperature differences.
Scientists used a robotic device to gather samples of 1 billion microbes every four hours, creating a time-lapse montage of their daily labors over two days. The study reveals synchronized metabolic gene expression among nonphotosynthetic microbes in response to environmental changes.
Three WHOI projects will investigate the complex interactions between marine microbes, nutrients, and their environments using advanced technologies and methods. The grants aim to improve understanding of microbial communities and their impact on ocean health and productivity.
The American Gut project aims to characterize the microbes living in and on human bodies, with a focus on diet and lifestyle's impact on health. The public is encouraged to participate, and the study will analyze data from tens of thousands of individuals.
Researchers mapped genetic differences between domesticated fungus Aspergillus oryzae and its wild relative, finding extensive genome remodeling. The study suggests microbes undergo metabolic changes for desired functions rather than growth and form alterations.
A new NIST report summarizes efforts to advance indoor microbial sampling, highlighting challenges and future priorities for surface and aerosol analysis. The report explores cross-cutting issues such as education and public awareness, and provides a comprehensive overview of existing resources.
The Dip Chip technology uses genetically modified microbes to detect toxicity in real time, providing a quick and accurate diagnosis. The device can identify overall toxicity levels, picking up on any toxic materials, including those that have not been discovered yet.
A Michigan State University study found that antibiotics in pig feed increase the number of antibiotic-resistant genes in gastrointestinal microbes in pigs. This could contribute to the development of strains of microbes resistant to conventional antibiotics, which are potentially harmful to humans and animals.
Two wine yeasts, S. cerevisiae and Dekkera bruxellensis, have been studied to reconstruct the evolutionary history of ethanol production. They developed similar abilities around 100-150 million years ago, likely driven by environmental pressures such as competition from other microbes.
Canada Research Chair Barbara Sherwood Lollar's research examines the effectiveness of bioremediation technologies in cleaning up groundwater contamination. Her techniques use isotopic signatures to track clean-up progress, providing a critical framework for regulators and practitioners.
Biologists at UC Berkeley have developed a new 'reverse-ecology' tool that analyzes genomes to identify an organism's adaptive traits. The study, using Neurospora crassa bread mold, found variations in two genome regions linked to natural selection and cold tolerance.
A study published in Science reveals nearly 30,000 novel enzymes that can efficiently degrade plant cell wall materials, a major breakthrough for large-scale biofuel production. The discovery sheds light on the molecular machinery used by microbes in the cow's rumen to break down biomass into simple sugars.
A study published in Nature Reviews: Microbiology examines the cellular mechanisms of microbial dormancy and its implications for ecosystems. Dormant microbes can have a significant impact on biodiversity, carbon emissions, and nutrient cycling, making them a key component of ecosystem resilience.
Researchers at UMass Amherst have identified a new cooperative behavior in anaerobic bacteria, allowing microorganisms to form direct electrical connections and pass electrons. This discovery has significant implications for the global carbon cycle and bioenergy production.
Researchers from the USDA have identified a group of enzymes known as feruloyl esterases that can break down key links between plant cell wall polymers. These enzymes, produced by certain microbes, have been isolated and cloned for use in Escherichia coli to improve biofuel production efficiency.
A University of Illinois scientist has identified four genes that increase alcohol tolerance in yeast, leading to higher ethanol yields and productivity. The discovery aims to make biofuel production more efficient and economical by reducing the toxic effects of biofuels on yeast.
A new survey method reveals a broader and more diverse array of metal-driven chemical processes in microbes than previously recognized. The research could lead to innovative biofuels and bioremediation technologies.
A Purdue University researcher has identified a yeast gene that increases the production of a compound slowing aging and delaying microbial decay in tomatoes. This discovery may lead to extended shelf life for most fruits by an additional week, benefiting areas with limited access to fresh produce.
The Human Microbiome Project has launched a centralized database for sequencing microbial genomes, providing a unique resource for future investigations. The HMP has cataloged over 1,400 individual human microbiome projects, enabling researchers to study the interactions between human and microbial cells.
Researchers at NC State will use microbes that thrive in high-temperature environments to produce biofuels directly from carbon dioxide and hydrogen. The project aims to create a more efficient and flexible process for producing biofuels, which could be used in various applications.
Researchers used high-performance computing to locate small genes missed by scientists, uncovering 380 families of undetected gene families. The study used an ephemeral supercomputer to perform an all-to-all sequence search, reducing the search time from nearly 90 years to just 12 hours.
A team of scientists has discovered that rare microbial organisms, once thought to be undetectable, dominate the ecosystem in a unique hydrothermal vent field. The study, led by William Brazelton at the University of Washington, found that microorganisms can remain rare for long periods before becoming dominant when ecosystems change.
Researchers are studying phototrophic extremophiles to understand the evolution of oxygen-evolving high-energy photosynthesis. The study aims to illuminate gaps in genetic data and explore astrobiology connections, potentially revealing clues about extraterrestrial life.
Scientists have discovered a bowl-shaped molecule that can pull carbon dioxide out of the air, offering new possibilities for reducing greenhouse gas emissions. The molecule's unique properties make it suitable for industrial use in removing CO2 from ambient air and potentially even from living organisms.
The development of genome annotation standards is crucial for advancing microbial genomics, but a lack of standards hinders comparisons and discoveries. Kyrpides suggests several innovative approaches to ease the data processing bottleneck, including proxy approaches and pan-genome representations.
A study found that rats in Baltimore form distinct neighborhoods, with each community spanning little more than an average alley. Rats rarely migrate, but neighborhood eradication efforts may backfire by encouraging rodents to repopulate other areas and spread disease.
Researchers have found a way to induce sex in the disease-causing parasite Leishmania by cramming enough parasites into the gut of an insect, potentially leading to new treatments for deadly infections.
Michigan State University has licensed technology that enables plants to use atmospheric nitrogen, resulting in significant growth and yield improvements of up to 90 percent. The microbial fertilizers are cost-effective, environmentally friendly, and have been shown to increase plant resistance to disease.
Researchers have identified a stable, modifiable virus capable of withstanding harsh conditions and can be used as a nanobuilding block. The virus particles are ideal for producing materials on the nanometre scale and can be modified spatially controlled.
The metagenomics field is gaining traction, allowing researchers to reconstruct metabolic profiles of microbes from environmental samples. DOE JGI's advancements in this area are crucial for understanding microbial diversity, as they have characterized many metagenomes across various ecosystems, including acid mine drainage and gut env...
A novel approach extracts single genomes and discerns specific microbial capabilities from mixed community sequence data. The research team characterized biochemical pathways associated with nitrogen cycling and methane utilization in Lake Washington sediments, revealing novel versions of metabolism.
The Genome Sequencing Center at Washington University School of Medicine increased its sequencing capacity with the acquisition of five new Genome Sequencer FLX Systems from Roche Diagnostics. The center will be able to support a wide variety of projects, including transcriptome analysis of individual tumors and human microbiome studies.
Researchers at Michigan State University found that clones with similar genetic traits outperformed those with varied genetics, producing more flowers and potentially increasing reproduction. The study suggests that a gene called Erecta plays a role in this variation, but further research is needed to confirm the findings.