Articles tagged with Virus Testing
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A newly-developed dipstick test sensitively identified Zika virus and all four dengue virus subtypes with no cross-reactivity. The test detected viral proteins at lower concentrations, making it a potential tool for diagnosing emerging pathogens.
Researchers have developed a new test that can provide results in just hours for diagnosing bacterial infections like Strep throat. The test uses lipid vesicles to detect beta-hemolytic bacteria with 100% accuracy on plates and 99% accuracy in liquid broth.
Researchers found that nearly half of ecstasy users tested positive for drugs they denied using, particularly new stimulants like 'bath salts'. The study highlights the risks of unintentional drug use in EDM environments and emphasizes the need for harm reduction efforts and evidence-based information on adulteration.
Researchers developed self-powered, paper-based devices that detect biomarkers and identify diseases with high accuracy. The devices use electrochemical analyses powered by the user's touch and can be used in remote villages or military bases without requiring electricity or additional equipment.
Researchers have identified a potential method to screen for Zika virus exposure using proteomics in saliva. The study found that specific protein signatures can be detected in the saliva of infected individuals, allowing for earlier detection and treatment of the virus.
Researchers developed a test that detects Zika virus presence in blood in minutes, using gold nanorods on paper. The test relies on an immune response caused by the virus and doesn't require refrigeration, making it suitable for resource-limited settings.
A new portable platform enables sensitive and rapid diagnostic testing in resource-limited settings, detecting telltale markers of disease as accurately as the most sensitive tests on the market. The D4 assay can identify a disease biomarker in as few as 15 minutes.
A randomized trial found that same-day ART initiation improved retention (80% vs. 72%) and evidence of ART working (53% vs. 44%), with further improvements needed to hit UNAIDS 90-90-90 targets. The study supports accelerating HIV testing and treatment processes.
Researchers found standard maternal screening methods can overlook cases of congenital CMV infection in up to 70% of women. A more comprehensive approach, including PCR tests on all newborns, is needed for early detection and treatment.
A new saliva test developed by Johns Hopkins researchers matches the performance of a widely used blood test for diagnosing hepatitis E virus infection. The test has the potential to ease and speed up research into the disease, which affects an estimated 20 million people worldwide each year.
A new antibody-based assay developed by researchers at UC Berkeley and Humabs BioMed has shown very high sensitivity and specificity in distinguishing Zika virus infections from those caused by similar viruses. The test is simple, cost-effective, and can be used to detect both recent and past Zika virus infections.
By adding polydopamine, a material isolated from shellfish, scientists can increase the sensitivity of common bioassays by 100-1,000 times, enabling more accurate diagnoses and reducing uncertainty in laboratory research.
A study of over 450,000 women found that HPV testing led to a 15.8% increase in cervical precancer detection and shorter time to diagnosis, but also resulted in more biopsies and surgical procedures. The benefits of HPV testing outweigh the harms, but caution is needed due to potential overtreatment.
Australian researchers have developed a world-first test to identify patients at risk of developing serious secondary infections. The High-risk Influenza Screen Test measures an early warning signal released by the patient's body, predicting potential complications with high accuracy.
A new OpenArray system offers simultaneous detection of multiple viruses, bacteria, and protozoan pathogens in human blood samples, demonstrating a promising tool for flexible and accurate blood screening. The device was tested with 92 donor samples and showed 95% accuracy in identifying virus-positive samples.
Researchers created a rapid biosensor to detect early-stage flu virus infections, outperforming existing kits in sensitivity and speed. The new device can identify minuscule amounts of H1N1 virus, allowing for timely administration of antiviral medication.
Scientists at the University of Pittsburgh have developed a test sensitive enough to detect 'hidden' HIV, which reveals that people who appear cured may still carry a larger virus reservoir than previously estimated. The test, called TZA, is faster, less labor-intensive and less expensive than existing tests.
A new test based on a patient's epigenetics may accurately identify those at highest risk of anal cancer, minimizing painful procedures and over-treatment. This test has the potential to reduce costs, pain, and anxiety associated with diagnosis, particularly in high-risk groups such as men who have sex with men and people with HIV.
Scientists have developed a rapid and low-cost diagnostic device that can detect influenza A with 70% accuracy. The point-of-care test is fast, easy to use, and costs less than $6 per device, making it a promising solution for doctors and hospitals in preventing the spread of flu pandemics.
A new study by Colorado State University researchers demonstrates a method to quickly detect Zika virus in mosquito populations, informing decision-making on disease-prevention methods. The use of loop-mediated isothermal amplification (LAMP) allows for easy detection in human and mosquito samples from the US, Brazil, and Nicaragua.
A new detection test for Zika virus distinguishes between African and Asian strains, improving tracking efforts. The low-cost LAMP test is faster than current gold-standard methods, with minimal processing requirements.
A new AI-based image detection method has shown promise in screening for cervical cancer, detecting abnormalities with higher sensitivity and specificity than traditional methods. The technique, developed by Lehigh University researchers, could be used to improve early detection and treatment of the disease in resource-poor regions.
Scientists at Columbia University's Mailman School of Public Health report elevated levels of Babesia microti, a pathogen responsible for babesiosis, in Suffolk County, New York. The new test can strengthen surveillance for tick-borne illnesses, which are underreported and growing rapidly.
A new report emphasizes the importance of prioritizing rapid diagnostic tests for life-saving diseases, similar to pregnancy tests. The tests can help tackle antibiotic resistance and improve global health. However, lack of funding and profile are major barriers to their widespread adoption in low- and middle-income countries.
Research detects fragments of Zika virus RNA in Asian tiger mosquito eggs collected in Brazil, highlighting potential role in Zika transmission. The findings emphasize the need for further research into additional vector species.
A new point-of-care testing strategy has been developed to quickly diagnose respiratory infections, including flu, allowing for faster treatment and reduced risk of antibiotic overuse. The test, which can deliver results within an hour, has shown promising results in trialling patients with acute respiratory illnesses.
A new rapid blood test to diagnose and quantify the severity of active TB cases has been developed by a team of researchers from Arizona State University. The NanoDisk-MS assay can detect minute blood levels of two proteins that are released only during active infections, providing faster results than current tests.
Researchers have developed effective Zika virus nucleic acid amplification technology assays to screen donated blood supplies. The methods demonstrated excellent sensitivities and were substantially more sensitive than most other laboratory-developed and diagnostic Zika virus assays.
Researchers have developed a rapid-testing prototype that weighs under a pound, costs as little as $100 and can detect mosquito-borne illnesses within 30 minutes. The device uses loop-mediated isothermal amplification (LAMP) diagnostic method to test for Zika, dengue and chikungunya viruses.
Researchers found HTLV-1/HIV co-infected patients had higher CD4+ T-cell counts after treatment, which didn't predict response to therapy. Viral load testing was shown to be more effective in monitoring ART response, contrary to current CD4+ T-cell count use.
Researchers from Florida Atlantic University developed a portable device that can detect the Zika virus using just a saliva sample, providing an affordable and rapid solution to diagnose the outbreak. The device, based on technology developed for HIV detection, aims to distinguish between Zika and other flaviviruses.
A new biosensor developed by CSIC can detect HIV-1 p24 antigen up to 100,000 times lower than previous methods, reducing the undetectable phase after infection to just one week. The technology also shows potential for early detection of certain types of cancer.
Researchers have created a new detection test for Zika that is faster and more accurate than existing tests. The new test can identify the virus in a tiny blood sample in under four hours, marking a significant improvement over current options.
A UCF researcher has developed a method that uses nanoparticles and Faraday rotation to measure protein quantities in test solutions, allowing for faster biochemical immunology test results. This technique could lead to faster diagnoses for HIV, Lyme disease, syphilis, and other infectious conditions.
The 'test and treat' scheme aims to reduce GP consultations and antibiotic prescriptions, but lacks robust evaluation and may not be cost-effective. The NHS England plan is based on limited data from a small pilot, which raises concerns about its scalability and potential impact.
Scientists have identified seven key proteins in the Zika virus genome that may be responsible for its damaging health effects. The study provides valuable clues for future research on how the virus interacts with human cells and how to develop treatments or prevention strategies.
A study found a 64% spike in genetic tests for breast cancer following Angelina Jolie's op-ed piece, but no uptick in mastectomy rates. The tests did not lead to additional breast cancer diagnoses, suggesting overtesting among low-risk groups.
A new blood test can detect Merkel cell carcinoma (MCC) earlier and more effectively than traditional imaging studies. The test uses an immune system marker to identify patients at high risk of recurrence, allowing for earlier treatment with immune therapy.
Researchers developed a blood test to assess human exposure to Aedes mosquitoes by measuring antibodies against one individual peptide from Aedes saliva. The test showed decreased human exposure to mosquito bites after a vector control program, with 88% of people having a positive antibody reaction before the intervention.
Researchers at Kobe University developed a new method to predict congenital CMV infection in fetuses using non-invasive tests. The most effective methods are ultrasound and PCR tests for uterine cervical secretion, which can accurately identify affected infants and enable early antiviral treatment.
Researchers developed a novel urine test to predict high-risk cervical cancer with 90.9% accuracy using genetic markers from HPV and human cells. The test shows promise as a cost-effective alternative to existing methods, which may be unnecessary in up to 50% of cases.
Scientists at Imperial College London have created a compact HIV test on a USB stick that can detect the virus in under 30 minutes. The device monitors viral levels to track treatment efficacy and prevent medication resistance.
A randomized trial found that providing pregnant and postpartum women with multiple HIV self-tests increased the likelihood of their male partners being tested for HIV. The study showed a significant increase in partner testing, with 90.8% of partners tested within three months of enrollment, compared to 51.7% in the control group.
The Walter Reed Army Institute of Research has begun a Phase 1 human clinical trial to test the safety and immunogenicity of the ZPIV vaccine, developed using an inactivated flavivirus vaccine platform. The trial involves 75 healthy adults and is part of the US Department of Defense response to the ongoing Zika virus outbreak.
Researchers at Thomas Jefferson University have developed a new test to determine immune cell strength, which could help predict patient reactions to various threats. The CaFlux test uses calcium channel detection to assess T-cell responses, offering insights into potential allergies or autoimmunity.
A rapid blood test using C-reactive protein (CRP) can rule out serious infections in nearly 40% of 'at-risk' children. The test reduces unnecessary hospital referrals and anxiety for less seriously ill children.
Researchers at UC Riverside and Riverside University Health System found that late-HIV diagnosed individuals are more likely to transmit the virus to others due to untreated viral loads. This increased risk also leads to negative health outcomes, including premature death and opportunistic infections.
A rapid blood test using a finger prick can detect serious infections in children within minutes, allowing general practitioners to diagnose more quickly. The test, which measures C-reactive protein levels, is not meant for all ill children but can help identify those with serious symptoms.
Extending cervical screening intervals for HPV negative women aged 40+ is safe due to low risk of CIN3+, but not recommended for those testing positive for HPV. Tailoring screening to individual risks using HPV test results and age may improve efficiency and optimal prevention.
A study reveals inadequate laboratory testing capacity and underutilization of existing technologies, limiting the ability to meet global HIV targets. This shortcoming affects countries' capacity to monitor HIV infection and provide antiretroviral therapy.
Researchers developed a rapid 5-minute test to detect C-reactive protein, reducing unnecessary antibiotic prescriptions for respiratory infections. The study showed significant reductions in antibiotic use among adults and children with viral infections.
A universal one-time HCV screening based on age can bypass discomfort and democratize preventive care, increasing screenings among all demographics. The screening test detects the virus antibody, with fewer than 1% of targeted baby boomers testing positive, yet helping identify those who benefit from curative treatment.
Researchers found that Grindr's ad campaign effectively reached untested high-risk populations, increasing the distribution of HIV self-testing kits. The study showed that 74% of test recipients had last been tested for HIV over a year ago, highlighting the need for targeted testing initiatives.
Researchers at Stanford University School of Medicine developed a diagnostic test that can distinguish between bacterial and viral infections using just seven human genes. The seven-gene test is more accurate, cheaper, and faster than earlier tests, with the potential to reduce antibiotic misuse and save healthcare systems money.
Researchers created a low-cost, portable genetic test for the Zika virus that can detect genetic material and requires no electricity or technical expertise. The test takes about 40 minutes to run and has shown sensitivity equivalent to RT-PCR tests.
A team of experts has proposed a standard list of essential diagnostic tests to support the use of medicines listed on the Model List of Essential Medicines. The list includes 147 critical laboratory tests across 57 categories, which can guide the use of many different EML drugs and improve healthcare quality in developing nations.
A new portable test has been developed to detect the Zika virus in saliva for just $2, making it a promising tool for managing outbreaks. The test can accurately detect low levels of the virus and distinguish it from similar viruses like dengue.
A new PCR multiplex method makes lab testing more effective for diagnosing persistent diarrhea caused by bacteria or parasites. Accurate diagnosis is crucial to determine treatment, as antimicrobial therapy can be useful but only for those who test negative for a pathogen.
Rabies tests fail to yield accurate results in over half of positive samples, raising concerns for human safety. The study highlights the need for improved quality control measures among producers to ensure the reliability of these tests.
Researchers found that several commercially available tests for hepatitis C virus core antigen are highly sensitive and specific, potentially replacing the current two-test screening process with a single test. This could streamline care in low- and middle-income countries where HCV is prevalent, but patients are often lost to follow-up.