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OSKTF rejuvenation enhances corticospinal repair after stroke

Researchers found that OSKTF-mediated neuronal rejuvenation boosts rehabilitation-driven corticospinal tract (CST) repair after ischemic stroke. The study demonstrated that combining OSKTF expression with rehabilitative training significantly enhances CST axon sprouting and skilled locomotor function recovery.

SourceCompuscript Ltd·JournalGenes & Diseases·DateAug 10, 2026

Study hints at how early life experiences may affect brain wiring

Researchers observed that chandelier cells, which regulate cortical circuit activity, communicate with other neurons shortly after birth, influencing brain development. This interaction is crucial for normal brain function and may be disrupted in neurological disorders.

SourceOhio State University·JournalScience Advances·DateMar 9, 2022