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Study suggests association between cognitive activity and brain protein related to Alzheimer's disease

Researchers found a direct association between cognitive engagement and lower levels of β-amyloid protein, which is associated with Alzheimer's disease. Participants who engaged in cognitively stimulating activities had reduced β-amyloid uptake, while those with the lowest activity had higher uptake comparable to patients with AD.

SourceJAMA Network·JournalArchives of Internal Medicine·DateJan 23, 2012

Lifelong brain-stimulating habits linked to lower Alzheimer's protein levels

A new study reveals that people with no symptoms of Alzheimer's who engaged in cognitively stimulating activities throughout their lives had fewer deposits of beta-amyloid, a destructive protein that is the hallmark of the disease. Lifelong cognitive engagement may affect a primary pathological process in the disease, suggesting potent...

SourceUniversity of California - Berkeley·JournalArchives of Neurology·DateJan 23, 2012

The influence of estrogen on female mood changes

Research suggests that estrogen can improve mood in women, particularly during the premenstrual phase. Studies have shown a significant increase in activity in brain areas related to emotional processing premenstrually, and estrogen has been linked to reduced symptoms of depression and anxiety in postmenopausal women.

NIH study finds stroke risk factors may lead to cognitive problems

A recent study by the National Institutes of Health has discovered a correlation between high blood pressure and stroke risk factors with cognitive impairment. The research, which followed over 30,000 participants, found that age, left ventricular hypertrophy, and high blood pressure were independent predictors of cognitive decline.

The cerebellum as navigation assistant

The cerebellum contributes to creating a cognitive map of the environment through altering chemical communication between its neurons. Inactivation of this ability impairs navigation, as seen in transgenic mice lacking long-term depression in cerebellar neurons.

SourceRuhr-University Bochum·JournalScience·DateNov 3, 2011

3 in 1: team finds the gene responsible for three forms of childhood neurodegenerative diseases

A Montreal-led international team identified the mutated gene POLR3A as responsible for three forms of leukodystrophies, a group of childhood-onset neurodegenerative disorders. The findings provide crucial insights into diagnostic tests and genetic counseling, as well as potential therapeutic strategies to replace defective genes.

SourceMcGill University·JournalAmerican Journal of Human Genetics·DateSep 12, 2011

Your brain on androids

A team of researchers led by Ayse Pinar Saygin found that the human brain responds with a mismatch in perception when an android's appearance and motion are at odds. This phenomenon, known as the 'uncanny valley,' occurs when an artificial agent becomes too human-like, causing discomfort and unease.

SourceUniversity of California - San Diego·JournalSocial Cognitive and Affective Neuroscience·DateJul 14, 2011

BPA-exposed male deer mice are demasculinized and undesirable to females, new MU study finds

Researchers found that BPA-exposed male deer mice are less desirable to females, perform poorly on spatial navigation tasks, and exhibit random trial-and-error strategies. The study suggests that exposure to BPA during human development could be damaging to behavioral and cognitive traits unique to each sex.

SourceUniversity of Missouri-Columbia·JournalProceedings of the National Academy of Sciences·DateJun 27, 2011

Picower: 1 skull + 2 brains = 4 objects in mind

A study by MIT neuroscientists found that humans have two independent capacities for working memory, rather than one general capacity of four objects. This discovery resolves a long-standing debate in the field and has significant implications for designing more effective cognitive therapy, brain games, and visual displays.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJun 20, 2011

Clever tool use in parrots and crows

Researchers investigated problem-solving abilities and innovative capacities of kea and New Caledonian crow. The studies revealed that both species employ various tools to achieve food rewards, with the kea mastering compact object tools and the crow using elongated objects like sticks to probe for grubs.

SourceUniversity of Vienna·JournalPLOS ONE·DateJun 10, 2011

Controlling brain circuits with light

The invention of optogenetics enables scientists to control and observe brain circuits using genetically encoded molecules targeted by light. This technique reveals how entire neural circuits operate, allowing researchers to determine the roles of specific neurons in various behaviors and brain functions.

SourceFaculty of 1000·JournalF1000 Biology Reports·DateMay 3, 2011

Musical activity may improve cognitive aging

A study found that older individuals who played a musical instrument throughout life performed better on cognitive tests than non-musicians. The study suggests that musical activity may serve as a challenging cognitive exercise, making the brain fitter and more capable of accommodating aging challenges.

SourceEmory Health Sciences·JournalNeuropsychology·DateApr 20, 2011

Juggling languages can build better brains

Research suggests that bilingual speakers outperform monolinguals in certain mental abilities, such as editing out irrelevant information and prioritizing tasks. This 'mental juggling' skill allows bilinguals to better navigate between languages and enhances their cognitive flexibility.

New study finds no cognitive impairment among ecstasy users

A large-scale study has found that ecstasy users show no signs of cognitive impairment attributable to drug use. The research, funded by $1.8 million from the National Institute on Drug Abuse, aimed to minimize methodological limitations of earlier studies and compared 52 ecstasy users with 59 non-users.

SourceWiley·JournalAddiction·DateFeb 15, 2011