A study published in Cornea reveals that aniridia not only alters corneal structure but also affects sensory nerve function, leading to a progressive decline in corneal sensitivity. In adulthood, patients experience difficulty distinguishing stimulus intensity and reduced tear production, compromising eye defense mechanisms.
Danielle Mor, a neuroscientist at the Medical College of Georgia, has been awarded $2.3 million to study the progression of Parkinson's disease through the use of C. elegans and innovative research approaches. Her goal is to understand how misfolded proteins spread from the gastrointestinal tract to the central nervous system.
Researchers have discovered a gene called NANOG that can improve nerve regrowth and re-establish innervation in damaged muscles after traumatic nerve injuries. This discovery has significant potential to help mitigate long-term disability for people with debilitating nerve injuries.
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A new study presents a novel surgical technique for treating Moebius syndrome, a rare condition that prevents smiling and affects social engagement. The technique involves utilizing the ipsilateral facial nerve to power gracilis free functional muscle transfer in select patients with residual facial nerve activity.
Researchers investigate centro-cingulate network changes and cholinergic innervation deficits in Parkinson disease and normal aging. Studies reveal significant correlations between centro-cingulate changes and cognitive impairments, motor symptoms, and age.
A UC Riverside study identifies how a Fragile X gene mutation contributes to premature ovarian failure, leading to early infertility. Researchers found that the mutation affects neurons regulating reproduction in the brain and ovaries, causing an increase in hormone production and faster secretion rates.
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A study published in Disease Models & Mechanisms reveals that premature differentiation of pain-sensing neurons and increased mechanosensory neuron production contribute to the development of pediatric dysphagia. The researchers found that disruptions in neural crest cell interactions lead to cranial nerve dysfunction.
A new study reveals that sensitive skin surfaces are overrepresented in the brain due to stronger connections between sensory neurons and brain stem neurons. This mechanism may explain why certain body parts, like hands and lips, are more sensitive than others.
Researchers at Tufts University successfully treated blind tadpoles with a serotonin receptor drug to induce nerve growth and promote visual learning, enabling the animals to process visual information from their grafted eyes. The study provides a potential road map for promoting innervation in regenerative medicine.
A new minimally invasive method provides obstetricians with detailed information on the anal sphincter innervation before child delivery, enabling them to perform episiotomies safely and minimize damage. The technique has been tested on 250 women in 10 EU countries.
Researchers at the University of Iowa have identified the mutated protein responsible for a common eye mobility disorder. In a study published in Neuron, they found that a unique swelling in one of the nerves to the eye muscle causes the defect, and that breeding mice with this mutation can enhance the effect.
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Researchers have discovered that nerves from the sympathetic branch of the nervous system (PSNS) are connected to fatty tissue, influencing its growth and function. This finding may lead to a better understanding of obesity-related conditions such as type II diabetes and high blood pressure.