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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Reactivating memories during sleep improves motor skills

Researchers found that reactivating memories during sleep improves motor skills by enhancing learning of new motor tasks. The study showed participants performed better without sound cues after a nap, indicating improved memory recall and muscle activation.

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Big brains and dexterous hands

A recent study by Sandra Heldstab and colleagues found that primate species follow fixed neural development patterns when learning fine motor skills. Humans develop their abilities later than other primate species due to the less developed state of our larger brains at birth.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Exercise boosts motor skill learning via changes in brain's transmitters

Researchers at the University of California San Diego have identified key neurological modifications following sustained exercise, leading to improved learning for motor-skill acquisition. Exercise has been shown to promote neurotransmitter switching, which enhances motor coordination and skill learning.

Some learning is a whole-brain affair, study shows

Research shows increased AMPAR activity in both motor and visual cortex during learning tasks, indicating a whole-brain approach to motor control. This challenges the long-held assumption that motor-based learning occurs solely in specific brain regions.

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Learning motor skills requires the 'feeling' part of the brain

Researchers found that inhibiting somatosensory cortex disrupts retention of motor memories, while motor cortex inhibition has no effect. This discovery sheds light on the consolidation process of motor skills and may have implications for rehabilitation and re-learning after injury.

Illumination of abnormal neuronal activities caused by myelin impairment

A study published in GLIA found that myelin impairment causes uncoordinated electrical impulse transmission between neurons, affecting motor learning in mice. The research also showed that compensating for impaired motor learning by pairing actions with brain photo-simulation can promote synchronization of neuronal activities.

Take a break! Brain stimulation improves motor learning

Researchers found that brain stimulation during short breaks improves recall of learned motor sequences, even after several hours of practice has stopped. The study suggests that pauses between practice sessions solidify learning in the brain, and stimulation can enhance this process.

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Motor learning for precise motor execution

Researchers found that both internal models are necessary for precise movement: learning to move and where to move. This discovery may lead to the development of new clinical tests and training methods for athletes, particularly those with cerebellar ataxia.

MPFI scientist receives more than $2 million in funding

The Max Planck Florida Institute for Neuroscience (MPFI) awards Dr. Jason Christie $2,082,074 to investigate neural circuits in the cerebellum and their role in motor learning. The goal is to understand how neurons interact with each other to facilitate learning outcomes.

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Newly identified role for inhibition in cerebellar plasticity and behavior

Researchers have identified a new role for inhibition in regulating motor learning in the cerebellum, finding that inhibitory cell class molecular layer interneurons play a key role in modulating plasticity and learning behavior. This discovery provides fundamental insights into neural computation and mechanisms underlying motor learning.

Brain waves reflect different types of learning

Scientists have identified distinct neural signatures for explicit and implicit learning, which could guide the development of training techniques to mitigate learning and memory deficits. The findings may also help diagnose Alzheimer's disease at an earlier stage.

Certain immune reactions to viruses cause learning problems

A study published in Nature Medicine found that immune reactions to viruses can disrupt brain connections, leading to learning problems. The research team identified CX3CR1highLY6Clow monocytes as the key players in this process, releasing inflammatory signaling protein TNFα which blocks nerve cell connection formation.

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How the brain improves motor control

Researchers at Osaka University have discovered that error signals in motor cortices drive adaptation in reaching, a key finding in motor neuroscience. The study used artificial electrical stimulation to induce trial-by-trial improvements in motor control, shedding light on the neural mechanisms underlying motor learning and adaptation.

Ability to turn off genes in brain crucial for learning, memory

Researchers found that a specific enzyme is necessary to turn off genes after physical activity ceases, leading to faulty brain wiring and impaired learning. The inability to shut off these genes can affect motor skills and learning abilities, even in adults.

Researchers optimize methods to study neurons during motor activity

Max Planck Florida scientists have optimized techniques for studying motor learning in neurons of the cerebellum, enabling prolonged assessment of neural activity. This breakthrough allows for further characterization of continuously engaged neurons during motor activity and normal behavior.

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Practice makes perfect, York U brain study confirms

A new brain study confirms that practice makes perfect in professional ballet dancers, showing the long-term effects of learning complex dance motor sequences. The study found an inverted 'U' learning pattern, where brain activation increases during initial learning and performance, but then decreases as mastery is achieved.

Want to learn a new skill? Faster? Change up your practice sessions

In a study, researchers found that making small modifications to a task during repeated practice sessions can lead to faster skill acquisition. This is due to the process of reconsolidation, which strengthens motor skills by recalling and modifying existing memories. By adjusting their performance despite unawareness of subtle changes,...

Our elegant brain: Motor learning in the fast lane

Researchers at McGill University discovered that a small cluster of brain cells in the cerebellum engage in elegant computations to quickly compare expected and actual sensory feedback. This allows neurons to rapidly readjust and form new patterns in the brain to accomplish tasks.

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Learning with all the senses

Researchers found that associating foreign-language terms with gestures and images enhances learning outcomes, outperforming methods relying on listening or reading alone. The brain's motor system plays a crucial role in this process.

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Practice really does make perfect

Researchers found that distinct motor memories can be learned with unique follow-throughs, allowing for faster learning of multiple skills. Practising consistent follow-through enables tasks to be learned quickly, while variable follow-through activates multiple motor memories.

Distraction, if consistent, does not hinder learning

A new study published in Psychological Science found that consistent distraction during learning does not hinder learning, but rather helps recall motor skills. The researchers discovered that dividing attention between tasks during learning can create an internal representation that boosts recall when a similar cue is present.

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Motor cortex shown to play active role in learning movement patterns

Researchers discovered that motor cortex actively participates in learning new motor movements, revealing a more complex process than previously thought. The study found that different patterns of activity in the motor cortex accompany similar movements after learning, suggesting a crucial role in adapting to new actions.

Balancing old and new skills

The MIT model suggests that neurons constantly change connections to explore many possible solutions, but with a balance between hyperplasticity and low signal-to-noise ratio. This allows the brain to learn new skills while retaining previously learned ones, especially if they are not similar.

How sleep helps brain learn motor task

A new study by Brown University researchers found that sleep improves motor learning by changing fast-sigma and delta brainwave oscillations in the supplementary motor area. This reorganization is associated with improved speed and accuracy on sequential finger-tapping tasks after a few hours of sleep.

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Seeing our errors keeps us on our toes

Johns Hopkins researchers found that our brains don't forget skills by passive decay but instead deliberately select what to retain. This new understanding contradicts previous assumptions about the formation and loss of motor memories.

Roots of language in human and bird biology

Researchers at Duke University have found that the genes responsible for human speech share similarities with those used by songbirds. This discovery sheds light on the evolutionary roots of language and suggests a convergent complex trait like speech and song may be associated with similar genetic changes.

Alternating training improves motor learning

A study suggests that alternating between learning and unlearning an unusual walking pattern on a split-belt treadmill can improve motor learning in healthy adults. This approach may help patients relearn how to walk after stroke or injury, improving therapeutic outcomes.

Motor memory: The long and short of it

Researchers found that short-term and long-term motor memory compete against each other, with switching between tasks improving retention. USC scientists' discovery could lead to optimized computer programs for stroke patient rehabilitation.

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In motor learning, it's actions, not intentions, that count

Researchers at Harvard University's Neuromotor Control Lab found that motion-referenced learning, where the brain learns from actual movements rather than intended actions, can improve learning efficiency. This approach may lead to more effective neurological rehabilitation for individuals with stroke or other motor disorders.

Tweeting teenage songbirds reveal impact of social cues on learning

In a groundbreaking study, teenage male songbirds were found to significantly improve their singing in the presence of females, demonstrating the impact of social cues on learning. This finding has important implications for understanding human language acquisition and motor skill development.

Learning causes structural changes in affected neurons

Researchers found that learning causes significant structural changes in affected neurons, including a 22% increase in dendritic spines connecting them to other motor neurons. This discovery suggests that the adult brain is highly changeable and adaptable as it learns new information.

Unconscious learning uses old parts of the brain

A new study from Karolinska Institutet finds that the limbic striatum, an evolutionarily old part of the brain, is involved in implicit learning of motor sequences. This discovery sheds light on fundamental learning systems shared with primitive vertebrates and has implications for developing treatments for diseases like Parkinson's.

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Study shows new brain connections form rapidly during motor learning

Researchers at the University of California, Santa Cruz, found that new brain connections form quickly within one hour of training, leading to long-lasting memories. The study used mice with genetically altered fluorescent proteins to visualize changes in individual brain cells.

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Watching with intent to repeat ignites key learning area of brain

Researchers found that motor areas of the brain are activated in a fashion similar to actual movement when watching someone else perform a task with the intention of later replicating it. This discovery may prove important in improving rehabilitation for individuals suffering from brain or bodily injury.

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Brain study considers motor function, cognition with alcohol consumption

A study published in NeuroImage found that alcohol selectively suppresses cognitive activity in the frontal and posterior parietal brain regions, leading to poor coordination. This suppression is due to impaired feedback processing in brain areas critical for updating mental models for motor action.

Picking apart how neurons learn

Researchers identified two critical molecular events: PICK1's role in removing AMPA receptors and phosphorylation's effect on the receptor. These findings provide new understanding of long-term depression and its connection to motor learning, such as the vestibulo-ocular reflex.