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Our elegant brain: Motor learning in the fast lane

Researchers at McGill University discovered that a small cluster of brain cells in the cerebellum engage in elegant computations to quickly compare expected and actual sensory feedback. This allows neurons to rapidly readjust and form new patterns in the brain to accomplish tasks.

SourceMcGill University·JournalNature Neuroscience·DateAug 3, 2015

Neuroscientists decipher brain's noisy code

Researchers at Rice University deciphered how individual neurons predict behavior in perceptual tests, finding that neurons often share the same information. The study explains a long-standing paradox in neural activity and has implications for understanding neurological disorders such as Alzheimer's disease.

SourceRice University·JournalNeuron·DateJul 16, 2015

Modeling a nervous pathway involved in touch-induced behavior

Researchers Ache and Dürr develop a computational model of a descending mechanosensory pathway involved in active tactile sensing, capturing key properties of diverse neurons. The model is validated against real neuron coding properties and provides a common framework for modeling diverse neuron types.

SourcePLOS·JournalPLOS Computational Biology·DateJul 9, 2015

Seeing is believing

Researcher Richard Born's team at Harvard Medical School has discovered key principles about how the brain makes sense of visual information. They found that individual neurons are tuned to detect specific motions and relative depth, with a direct bottom-up contribution to these signals.

SourceHarvard Medical School·JournalNeuron·DateJul 1, 2015

Long-term memory formation

A team of NYU researchers discovered that two growth factor families, TrkB and TGFβr-II, play distinct roles in creating long-term memories by exerting their actions in different parts of the brain. At different times, these molecules swap roles to facilitate memory formation.

SourceNew York University·JournalNeuron·DateJun 3, 2015

Brain cells capable of 'early-career' switch

Researchers found that inactivating Lhx2 in mature neurons can reprogram them to process different senses, expanding one region at the expense of another. This discovery provides proof of brain plasticity and may lead to new therapeutic approaches for treating human disorders such as autism.

SourceSalk Institute·JournalProceedings of the National Academy of Sciences·DateMay 11, 2015

Breath taking

Scientists have identified two sensory neuron subtypes controlling different respiratory functions in mice, revealing a complex vagus nerve system that may lead to targeted therapies. The study sheds light on the molecular mechanisms underlying breathing control and has implications for treating various conditions.

SourceHarvard Medical School·JournalCell·DateApr 16, 2015

Feeling ducky

Researchers have identified ducks as an ideal model organism to study the cellular mechanisms of mechanosensation, a complex process involving sensory neurons. The study reveals that ducks have highly specialized trigeminal ganglion neurons that are capable of converting force into excitation more efficiently than other birds and mammals.

Walking on ice takes more than brains

A cluster of neurons in the spinal cord, known as RORα neurons, integrates sensory information from light touch sensors to control muscle movements. This 'mini-brain' helps regulate balance and prevents falls by making subtle adjustments to foot position.

SourceSalk Institute·JournalCell·DateJan 29, 2015

Neurons listen to glia cells

A team of scientists at Johannes Gutenberg University Mainz uncovered a new signal pathway in the brain that plays a crucial role in learning and sensory input processing. Glial cells release a specific protein fragment that influences neuronal cross-talk, leading to changes in neural networks.

SourceJohannes Gutenberg Universitaet Mainz·JournalPLOS Biology·DateDec 12, 2014

Pain and itch in a dish

Researchers at Scripps Research Institute have developed a method to convert human skin cells into sensory neurons, allowing for the study of pain and itch in a laboratory setting. This breakthrough enables the examination of neurodegenerative diseases such as Friedreich's ataxia and the testing of potential therapies.

SourceScripps Research Institute·JournalNature Neuroscience·DateNov 24, 2014

That pregnant feeling makes a fly start nesting

A study published in Cell Reports found that female fruit flies exhibit a preference for acetic acid, or vinegar, when carrying eggs due to sensory neurons detecting stretch in the reproductive tract. This behavior is linked to pregnancy and egg production, challenging previous assumptions about hormonal influences.

SourceDuke University·JournalCell Reports·DateOct 16, 2014

How female flies know when to say 'yes'

A study reveals that female fruit flies use a small number of excitatory neurons and neurotransmitters like acetylcholine to decide whether to accept or reject male courtship. The decision-making process is found to be generated in three brain regions, suggesting a complex circuit involving sensory inputs and neural signaling.

SourcePLOS·JournalPLOS Biology·DateOct 7, 2014

Memory in silent neurons

Neuroscientists found that sensory stimuli, even when neurons are silent, can generate long-term synaptic strengthening. This discovery challenges traditional models of synaptic plasticity and has implications for understanding learning and memory, as well as therapeutic possibilities.

SourceUniversité de Genève·JournalNature·DateAug 31, 2014

Driving brain rhythm makes mice more sensitive to touch

Brown University neuroscientists report that they have directly controlled the cells producing gamma brainwaves in mice, resulting in increased touch sensitivity. The study confirms the first direct evidence of gamma brainwaves affecting perception and attention, suggesting a more complex role for these brainwaves than previously thought.

SourceBrown University·JournalNature Neuroscience·DateAug 24, 2014

Controlling movement with light

MIT researchers successfully control muscle movement in awake and alert mice by applying blue light to their spinal cords via optogenetics. This technique reveals the function of inhibitory interneurons that form complex circuits with other neurons, allowing for precise control over specific subsets of neurons.

Neuroscience's grand question

Researchers have developed a new theoretical model to understand how cells monitor and self-regulate their properties in the face of continual cellular turnover. The model suggests that neurons use an internal gauge to adjust ion channel expression, but this system can lead to neuronal hyperexcitability and disrupt overall homeostasis.

SourceBrandeis University·JournalNeuron·DateMay 21, 2014

Illuminating neuron activity in 3-D

Scientists have developed a new imaging system that reveals neural activity throughout the brains of living animals in 3-D. The technique allows for simultaneous imaging of every neuron in the worm Caenorhabditis elegans and the entire brain of a zebrafish larva, providing a more complete picture of nervous system activity.

SourceMassachusetts Institute of Technology·JournalNature Methods·DateMay 18, 2014

A short stay in darkness may heal hearing woes

Researchers at the University of Maryland found that adult mice experienced improved hearing after simulated blindness, which could lead to new treatments for hearing loss and tinnitus. The study showed that temporary vision loss can rewire the brain's auditory system in adults, allowing for sharper sound discrimination and sensitivity.

SourceUniversity of Maryland·JournalNeuron·DateFeb 5, 2014