Roswell Biotechnologies has developed a molecular electronics sensor on a semiconductor chip, enabling real-time detection of single molecules for diverse applications including drug discovery, diagnostics, and DNA sequencing. The platform offers unlimited scalability in sensor pixel density and high resolution measurements.
Researchers have discovered two proteins, IGF-1 and IGFBP5, in urine samples that are significantly lower after a concussion. These biomarkers could help diagnose concussion and monitor recovery. The study suggests that urine testing could be an early and inexpensive way to detect concussions.
The Human Proteoform Project aims to characterize known proteoforms and discover new ones, ultimately establishing a comprehensive Human Proteome Atlas. This atlas will enable researchers to accelerate biomedical research and discovery, leading to improved diagnosis and treatment of diseases.
Researchers at the University of Helsinki and the University of Eastern Finland found six candidate drugs with antiviral effects against SARS-CoV-2. The study used a combination of modern technologies to identify protein targets for repurposed drugs, suggesting that existing compounds could be faster and safer alternatives.
Researchers develop DNA Nanoswitch Calipers to measure distances within single molecules using force, enabling the identification of single proteins in samples. This technique creates a unique 'fingerprint' that can be used to identify known molecules or infer structural information about unknown ones.
Researchers create maps of senescence in heart and lung cells, comparing different types of senescent cells across the lifespan. The goal is to understand how senescent cells contribute to age-related diseases and develop therapies called senolytics.
A new study developed a successful approach for identifying proteins in different types of neurons in the brain of a living animal. The technique uses a virus to tag neighboring proteins, allowing researchers to analyze the entire proteome inside living neurons.