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Aberrant mTOR signaling impairs whole body physiology

Research at the University of Basel reveals that aberrant mTOR signaling in the liver affects not only hepatic metabolism but also entire body physiology. The study found that activation of mTORC1 in the liver reduces locomotor activity, body temperature, and lipid metabolism.

SourceUniversity of Basel·JournalProceedings of the National Academy of Sciences·DateAug 11, 2014

Huntington's disease protein helps wire the young brain

A recent Duke University study has found that the mutated Huntington's disease protein is crucial for normal brain development and synaptic circuitry in early life. The research suggests that faulty connections may be the root cause of neurodegenerative disorders like Alzheimer's, with potential implications for treatment strategies.

Vitamin B12 accelerates worm development

Researchers at UMass Medical School develop a novel model to study the effects of vitamin B12 on gene expression and physiology in C. elegans worms. The study reveals that vitamin B12 regulates development through the methionine/SAM cycle and alleviates toxic buildups of propionic acid, leading to improved fertility.

SourceUMass Chan Medical School·JournalCell·DateFeb 13, 2014

Here comes the sun

Researchers at the University of Veterinary Medicine, Vienna, found that vitamin D deficiency stifferens blood vessels, leading to increased blood pressure and cardiovascular disease. The study used genetically modified mice to explore the effects of vitamin D deficiency on blood vessel flexibility.

SourceUniversity of Veterinary Medicine -- Vienna·JournalMolecular Endocrinology·DateJan 17, 2014

Misinterpretation of study

A study published in the journal Physiology & Behavior found that cats from multi-cat households do not exhibit higher stress levels than those from single-cat households. The researchers discovered that a cat's personality, as classified by its owner, plays a significant role in determining its stress response to stroking.

SourceUniversity of Veterinary Medicine -- Vienna·JournalPhysiology & Behavior·DateOct 16, 2013

For celebrated frog hops, scientists look to Calaveras pros

Researchers from Brown University traveled to Calaveras County to study the Guinness Book of World Records' top frog jumper, Rosie the Ribeter. They found that bullfrogs at the Jubilee surpassed the old research-grade mark of 1.3 meters a striking 58 percent of the time, with jumps reaching up to 2.2 meters.

SourceBrown University·JournalJournal of Experimental Biology·DateOct 16, 2013

Personality differences

A study found that socially dominant red deer individuals have faster heart rates and higher body temperatures during winter, leading to greater body mass loss when food is scarce. In contrast, subordinate individuals are better adapted to survive harsh conditions by reducing their metabolism and conserving energy.

SourceUniversity of Veterinary Medicine -- Vienna·JournalPhysiological and Biochemical Zoology·DateSep 18, 2013

Antioxidants -- too much of a good thing?

A recent study published in The Journal of Physiology found that high doses of the antioxidant compound resveratrol, commonly found in red wine and supplements, can block cardiovascular benefits of exercise in older men. This counterintuitive result highlights the complex relationship between antioxidants and exercise.

SourceWiley·JournalThe Journal of Physiology·DateJul 21, 2013

Nuke test radiation can fight poachers

Researchers developed a new method using radioactive carbon-14 from nuclear bomb tests to determine the age of ivory, helping to combat illegal poaching. The method has immediate applications in enforcing international trade bans and reducing demand for ivory.

SourceUniversity of Utah·JournalProceedings of the National Academy of Sciences·DateJul 1, 2013

Size of lunch dictates force of crunch

A new study reveals that bite force is influenced by the size of both the eater and the eatee, peaking at an optimal level of muscle stretch. The research found that too much or too little stretch leads to reduced bite force, with some fish able to crush stronger tubes when their muscles are optimally stretched.

SourceBrown University·JournalBiology Letters·DateFeb 12, 2013

Red hair is a sign of oxidative stress in wild boars, but gray is a-ok

Research found that wild boars with more reddish hair have higher levels of oxidative stress due to the consumption of glutathione by pheomelanin production. However, surprisingly, gray-haired boars showed signs of good condition and lower oxidative damage. This study suggests that different levels of melanin may have physiological con...

SourceUniversity of Chicago Press Journals·JournalPhysiological and Biochemical Zoology·DateJul 19, 2012