Blood Vessels
Articles tagged with Blood Vessels
Concordia-designed CPR simulator for space use tracks the differences of blood flow in reduced gravity
A Concordia-designed simulator models hemodynamics in reduced gravity environments, revealing key differences in blood flow and pressure patterns. The system successfully reproduced effective CPR on Earth and generated consistent blood flow under both normal and hypogravity conditions.
High-intensity interval training shows strongest vascular benefits in cardiovascular patients
High-intensity interval training shows strongest vascular benefits in cardiovascular patients. HIIE consistently improves flow-mediated dilation and vasodilation, with combined high-intensity programs showing the largest estimated effects on endothelial function.
Blocking stress signals could limit harmful inflammation after heart attack
Researchers discovered that stress hormones trigger neutrophils to detach from blood vessel walls and travel to the heart, causing inflammation. Blocking these stress signals with beta blockers may prevent excessive inflammation and improve heart healing.
One protein, two roles
Researchers found that Adgrl2 plays a crucial role in building both brain synapses and blood vessels, with different cell types producing distinct versions of the protein. Removing Adgrl2 from endothelial cells caused blood vessels to become leaky and lose their integrity.
Freeze-dried platelet product slows swelling and bleeding in TBI
A new freeze-dried blood product called Thrombosomes has shown promise in treating traumatic brain injuries by reducing swelling and bleeding. The product, derived from platelets with trehalose preservation, has been tested on mice and found to be effective in stabilizing damaged blood vessels.
New map reveals that blood vessels play an active role in disease
Researchers have mapped blood vessels in human adipose tissue with unprecedented detail, revealing that they are not only affected by disease but also play an active role in its processes. The study identifies unique cell types with mixed characteristics, suggesting a new approach to treating metabolic diseases.
In or out? Researchers uncover new controls on the brain’s ‘bouncer’
A team led by Jiefu Li developed a new method to examine proteins lining the inside surface of blood vessels, revealing two proteins and pathways that play a role in opening and closing the blood-brain barrier. This discovery could help scientists understand how the barrier functions and develop better ways to deliver medicines for neu...
Extended low-dose apixaban and superficial vein thrombosis
Extended low-dose apixaban effectively reduced symptomatic superficial vein thrombosis (SuVT) risk. Patients with enduring risk factors for SuVT benefited from this anticoagulation strategy.
Researchers identify new drug target to prevent development of dangerous blood vessel defects in brain
Researchers have identified TIE2 as a crucial link between two signaling pathways that drive the growth of blood vessel abnormalities in the brain. Inhibiting TIE2 with a small drug called rebastinib may provide an endothelial cell-centered approach to prevent CCMs, which can cause brain hemorrhages and seizures.
Research alert: How one receptor can help — or hurt — your blood vessels
A protein receptor, PAR1, plays a critical role in maintaining blood vessel structure. The receptor can trigger protective responses to counteract inflammation, potentially leading to new treatments for conditions like sepsis, heart attack, and stroke
In Rett syndrome, leaky brain blood vessels traced to microRNA
MIT neuroscientists have found that two genetic mutations causing Rett syndrome compromise the structural integrity of developing blood vessels, leading to leaky vessels. Overexpression of miRNA-126-3p is responsible for the vascular defect, which can be rescued by reducing the miRNA's levels.
Scientists find a mechanism for how exercise protects the brain
Scientists have discovered a mechanism that explains how exercise improves cognition by shoring up the brain's protective barrier. The study found that an exercise-induced liver protein strengthens the blood-brain barrier, reducing inflammation and cognitive decline associated with Alzheimer's disease.
Critical crosstalk between blood vessels and immune system, showing shared pathways in major diseases
The review outlines how vascular-immune crosstalk affects various diseases, revealing novel therapeutic opportunities. It highlights the shared embryonic origin of blood vessel cells and immune cells, as well as coordinated immune cell trafficking mechanisms.
New 3D imaging system could address limitations of MRI, CT and ultrasound
Researchers developed an innovative noninvasive technique that combines ultrasound and photoacoustic imaging to capture images of both tissue and blood vessels. The technology has the potential to address current gaps in medical imaging, providing faster and more comprehensive imaging at meaningful depths.
Cartilaginous cells regulate growth and blood vessel formation in bones
Researchers discovered subtypes of chondrocytes that transform into bone-building cells, regulating bone growth and vascularization. The study found that these cells secrete Thbs4 to induce blood vessel formation, shedding insights for treating defective angiogenesis.
Ultrasound pinpoints vascular complications from cosmetic fillers
A new study uses ultrasound to detect vascular complications from cosmetic fillers, such as absent blood flow to perforator vessels. Clinicians can now target exact areas for treatment, reducing the need for blind injections and minimizing complications like blindness and stroke.
Protein found to be key in blood vessel healing after surgical injury
Researchers have identified connexin 43 as a vital protein for endothelial repair in mice, which could lead to new therapies to improve recovery and reduce complications after vascular surgery. The study found that the protein helps blood vessels recover after damage, suggesting it could be a target for treatments.
Study shows why living in a disadvantaged neighborhood may increase dementia risk
Research found a strong link between living in deprived areas and poorer cognitive performance, with damage to brain small blood vessels and modifiable lifestyle factors contributing to the effect. Lifestyle habits such as exercise and sleep management also play a crucial role in dementia prevention.
Rapid blood pressure fluctuations linked to early signs of brain degeneration in older adults
A new study by USC researchers reveals that short-term 'dynamic instability' in blood pressure is linked to loss of brain tissue and nerve cell injury in older adults. This phenomenon, where blood pressure fluctuates wildly from one heartbeat to the next, may be a key risk factor for brain shrinkage and neurodegeneration.
Flavanols in cocoa can protect blood vessel function following uninterrupted sitting - study
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
How neurons go with the blood flow when migrating through the brain
Researchers discovered how newly created neurons rely on blood flow to migrate through the brain. The study found that blood vessels act as physical 'scaffolds' and that blood flow influences migration speed, with higher speeds seen in regions with abundant blood flow.
Microcatheter delivers therapies to the tiniest blood vessels
Researchers have developed a miniaturized magnetic microcatheter called MagFlow that can safely navigate the smallest and most intricately branched arteries in a matter of seconds. This innovation eliminates concerns about device removal and opens up new treatment avenues for cardiovascular conditions.
New drug-eluting balloon may be as safe and effective as conventional metal stents for repeat percutaneous coronary interventions
A new drug-eluting balloon has been shown to match the outcomes of standard care for in-stent restenosis, offering a safer alternative for patients with multiple stent layers. The study's results suggest that patients with complex or multilayer ISR may benefit from sirolimus-eluting balloons as a viable treatment option.
Hanyang University researchers develop novel sensor for continuous endoleak monitoring
A team of researchers has proposed a novel ultrathin flexible sensor inserted endovascularly to detect Type-I endoleaks with maximum rupture risk. The sensor is robust enough to withstand dynamic processes and exhibits long-term stability and functionality.
Galvanizing blood vessel cells to expand for organ transplantation
Researchers at Weill Cornell Medicine develop a new method to generate functional endothelial cells from adult tissue, potentially enabling vascular grafts and organ transplants. The approach involves using small molecules to trigger cell division without aging or losing function.
Why does female fertility decline so fast? The key is the ovary
Research reveals that ovarian aging is not just about egg quality, but also the surrounding cells and tissues. The study found that eggs cluster in pockets surrounded by egg-free zones, which decline in density with age, influencing egg lifespan and maturation.
Katerina Akassoglou receives Zenith Fellows Award to advance Alzheimer’s Research
Akassoglou's research discovered that blood protein fibrin causes toxic immune reactions in the brain, leading to neurodegeneration and disease progression. Her new immunotherapy aims to neutralize these effects, protecting against Alzheimer's and other neurological conditions.
Increased aerobic fitness in paediatric athletes is linked to yet poorly understood abnormal cardiovascular changes
A new study found that pediatric athletes' cardiovascular systems adapt to increased fitness with abnormal changes, including increased cardiac mass, central blood pressure, arterial stiffness, and carotid intima-media thickness. These changes are not yet fully understood and may have long-term effects on cardiovascular health.
USC researchers develop new brain imaging method to reveal hidden vascular changes with aging
Researchers at USC have developed a groundbreaking brain imaging technique that reveals how tiny blood vessels in the brain pulse with each heartbeat, which may hold clues to aging and diseases like Alzheimer's. The method shows that microvascular pulsatility increases with age, especially in deep white matter, a region critical for co...
Family Heart Foundation announces recommendations to improve universal screening for underdiagnosed genetic condition in children, which causes early onset cardiovascular disease
A multidisciplinary panel published in the Journal of Pediatrics advocates for accelerated diagnosis of familial hypercholesterolemia, a life-threatening genetic condition. Universal lipid screening is recommended to identify affected children at high risk of heart disease decades earlier than those without the condition.
Less invasive brainwave recording breakthrough
Researchers at The University of Osaka have developed a minimally invasive method for recording brain activity through blood vessels, offering high-fidelity recordings without the risks associated with traditional invasive approaches. This breakthrough could transform the diagnosis and treatment of neurological conditions like epilepsy.
Study illuminates contributing factors to blood vessel leakage
A new study from the University of Oklahoma has identified CD82 as a contributing factor to blood vessel leakage, which can initiate inflammation. The researchers found that lowering cholesterol levels with statins can strengthen vessel walls and reduce leakage.
Stem cells repair mouse brains post-stroke
Stem cell transplantation has been shown to reverse stroke damage in mice by regenerating neurons and restoring motor functions. The treatment also improved blood-brain barrier integrity, reduced inflammation, and promoted new blood vessel formation.
Artificial protein mimicking elastin aids tissue regeneration
Researchers developed a novel biomaterial called elastin domain-derived protein (EDDP) that overcomes natural elastin limitations. EDDP promotes cell adhesion and growth, aiding tissue regeneration in damaged tissues like heart valves, blood vessels, or torn ligaments.
New imaging approach simplifies retina exams by enabling digital refocusing
A new imaging approach has simplified retina exams by eliminating the need for mechanical focusing, making fundus cameras more accessible. The system uses a diffuser to capture 3D light information and digitally refocus images after they are taken, producing consistent resolution of about 7-10 line pairs per millimeter.
Scientists suggest new reason melanoma cells become more deadly
Scientists discovered that human melanoma cancer cells behave like stem cells when forced through channels narrower than 10 micrometres, gaining traits to survive, spread, and form new tumours. Researchers created a biomedical device to simulate blood flow through narrow blood vessels, showing the mechanical pressure makes cancer cells...
Two-photon microscopy uncovers hidden risks of brain capillary stalls
A new study using two-photon microscopy shows that brief interruptions in brain capillary flow can cause rapid drops in oxygen levels, potentially leading to tissue damage. The research found that even minor stalls can lead to significant hypoxia, highlighting the importance of uninterrupted blood flow to the brain.
New study finds hidden body fat is linked to faster heart ageing
A new study found that excessive visceral fat is linked to faster ageing of the heart, with a genetic predisposition to female-type fat in women potentially slowing heart ageing. Researchers also discovered that artificial intelligence analysis of images revealed signs of organ ageing, including tissue stiffness and inflammation.
Pusan National University unveils 3D-printed brain vessels to transform atherosclerosis research
A team of researchers created a 3D-bioprinted model of stenotic brain blood vessels to study the effects of abnormal flow patterns on endothelial cells. The model successfully replicated physiological conditions, including upregulation of inflammatory markers.
Neural navigation: FAU engineers, sensing institute map brain’s blood flow
Researchers from FAU and the Sensing Institute created a detailed computer model of the mouse brain's vasculature, simulating how brain blood vessels respond to hemodynamics and vasodynamics. The model shows that transitional vessels play a critical role in regulating flow and protecting the brain during increased activity.
How vessels in the lungs switch gears to promote healing
Researchers discovered that PAR1 triggers a structural transformation in lymphatic vessels, making them more permeable to absorb excess fluid and immune cells. This finding has implications for the treatment of lung diseases and could lead to targeted therapies.
Engineering functional liver organoids with organ-specific vasculature
A novel 3D culture method enables self-organization of precursor cell types into functional liver organoids capable of producing essential clotting factors. The breakthrough advances organoid-based therapies, drug testing, and disease modeling for liver diseases, including hemophilia A.
Genetics helps untangle the causes behind a rare and complex vascular disorder
A study from The University of Osaka reveals nearly half of patients with extracranial arteriovenous malformations carry mutations in the RAS/RAF/MAPK signaling pathway. These mutations were linked to abnormal vascular morphology and were frequently detected in younger female patients.
Gene networks decode human brain architecture from health to glioma
Gene coexpression analysis reveals optimal markers of cell types and states, providing opportunities for developing novel biomarkers and targeted treatment strategies for glioma patients. Dr. Oldham's work tackles the reproducibility crisis in science, emphasizing data metadata standardization.
A perfect fit: A Chinese Neurosurgical Journal study shows that Neuroform Atlas stent-assisted coiling is effective even in smaller arteries
A study published in Chinese Neurosurgical Journal found that the Neuroform Atlas stent-assisted coiling procedure is safe and effective for treating intracranial aneurysms in arteries less than 2.5 mm in diameter, with favorable outcomes and low postoperative complication rates.
Gamma-linolenic acid found to help relax constricted coronary arteries: A new insight into heart health
A new study found that gamma-linolenic acid (GLA) can directly relax constricted coronary arteries by blocking a key receptor. This discovery offers promising implications for preventing coronary spasms and angina. GLA's effects are comparable to omega-3 fatty acids, challenging previous beliefs.
New non-invasive method discovered to enhance brain waste clearance
Researchers have discovered a new method to enhance brain waste clearance by precisely stimulating the lymphatics under skin on the neck and face. This non-invasive approach may offer a safer alternative to current treatments for age-related neurological disorders, such as Alzheimer's disease.
Whether it's smoking or edibles, marijuana is bad for your heart
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
In vitro cancer model reveals how tumor cells access the bloodstream
Researchers developed a 3D in vitro culture system to study tumor cell behavior, finding that clusters can infiltrate blood vessels by disrupting the endothelial barrier. This discovery suggests new targets for cancer treatment strategies.
New study finds that tea and chocolate may help lower blood pressure
A new study published in the European Journal of Preventive Cardiology found that flavan-3-ols in tea and dark chocolate can reduce blood pressure readings. Regular consumption of these compounds was shown to improve blood vessel function, benefiting cardiovascular health.
MRI breakthrough could revolutionize diagnosis of common heart problem aortic stenosis
Researchers at University of East Anglia developed 4D flow MRI scan to diagnose aortic stenosis more accurately and reliably than current ultrasound techniques. The technology offers more accurate measurements of blood flow through heart valves, leading to better prediction of when patients need surgery.
Family Heart Foundation announces results of real-world study in 273,770 individuals with cardiovascular disease demonstrating that risk of subsequent cardiovascular event increases with rising lipoprotein(a) levels
A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.
Deepfakes now come with a realistic heartbeat, making them harder to unmask
Recent high-quality deepfake videos can feature realistic heartbeats and minute changes in face color, making them challenging to detect. Researchers found that even small variations in skin tone and facial motion can replicate the original pulse in deepfakes.
Scientists at the Lewis Katz School of Medicine at Temple University uncover how tau protein weakens the brain’s vascular defenses in Alzheimer’s disease
A harmful form of tau protein directly damages blood vessels in the brain, leading to inflammation and weakening the brain's protective shield. The discovery highlights the importance of focusing on early neurovascular changes mediated by tau to prevent or slow down damage to the blood-brain barrier.
Building ‘cellular bridges’ for spinal cord repair after injury
Researchers introduced a recombinant protein to pericytes, which change shape and create cellular bridges that support axon regeneration. In mouse experiments, the treatment promoted robust axon regenerative growth and restored leg function.
New research paves the way for better treatment of strokes
Researchers at Aarhus University have developed a new understanding of how brain blood vessels react after a stroke. By mapping the molecular changes, they hope to find targeted therapies to improve patient outcomes.
Montelukast improves retinal health in aging mice
A new study found that treating aged mice with montelukast improved retinal health by reducing inflammation and boosting proteasome activity. This approach may offer a promising new way to slow age-related vision loss and protect eye health in older adults.
Revealing brain energy dynamics: decoding the response to epileptic seizures
A study published by Tohoku University reveals that epileptic seizures can significantly reduce ATP levels in neurons, while increasing pyruvate levels in astrocytes. This finding challenges the traditional view of brain energy dynamics and suggests a more complex interplay between neuronal activity and metabolic processes.
Weight loss protects – even when weight is regained
A Swedish study of over 1,300 participants found that losing a significant amount of weight still offers protection against health issues like cancer and cardiovascular disease, even if some weight is regained. However, regaining weight can increase the risk of microvascular disease and other health problems.