Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A team of researchers from the University of Pittsburgh School of Medicine has identified a unique combination of blood proteins that distinguish IPF patients from normal controls with extraordinary sensitivity and precision. The five protein signature may help monitor lung fibrosis, detect disease progression, and evaluate treatment e...
Researchers in the Netherlands used Luminol to detect traces of blood on surfaces in their haemodialysis unit, highlighting infection risks. The results suggest that Luminol can be used as part of a hospital infection control regimen to monitor cleaning and disinfection procedures.
The US Department of Homeland Security has developed a wearable hood for emergency escape with 15-minute chemical protection. The EH-15 mask provides protection against chemicals and biologics, has a three-year shelf life, and highly efficient particulate filters.
Scientists are developing a new proteomics project to identify biomarkers for chronic liver disease, which could help predict the progression of the disease and lead to early interventions. The technology aims to detect liver disease via blood test, with potential applications in other diseases and commercialization.
Researchers found that multislice CT scans (MSCT) combined with D-dimer measurement were as effective as using MSCT alone and venous ultrasonography of the leg in detecting pulmonary embolism. This approach eliminates the need for venous ultrasonography, making it a cost-effective diagnostic strategy.
A recent meta-analysis of 15 studies involving over 70,000 participants identified six new genes linked to type 2 diabetes. The study, published in Nature Genetics, confirms that insulin-producing cells play a crucial role in the disease's development.
Researchers have discovered a protein profile in the blood that can help diagnose and treat chronic sinusitis with a totally objective test. This breakthrough may aid in more effective management of the disease, which is characterized by recurring nasal congestion, difficulty breathing, and sinus pressure.
A study of 804 individuals with early Parkinson's disease found that those with higher blood urate levels were less likely to progress and required dopaminergic therapy. The association suggests that urate may protect dopamine-producing neurons, potentially leading to the development of new therapies.
Research found that medial breast tumors primarily receive blood from internal mammary vessels, while lateral tumors have a more complex blood supply. This study supports the use of MRI for analyzing breast cancer's impact on surrounding anatomy, particularly vascular supply and lymphatic drainage.
During WWII, physiologists developed altitude chambers to study high-altitude effects on humans. They trained animals to parachute and discovered techniques to prevent decompression sickness and hypoxia. These innovations paved the way for pressurized aircraft and safer air travel.
Cornell researchers have identified 63 proteins in male mosquitoes' seminal fluid that can suppress female appetite for mammalian blood and stimulate egg production. The study's findings could lead to novel strategies to prevent dengue virus spread, a disease affecting 50 million people annually.
A tiny variation in the CHI3L1 gene increases blood levels of YKL-40, a biomarker for asthma. The genetic variation also lowers YKL-40 levels and protects against asthma. Researchers found similar connections between the CHI3L1 variations, YKL-40 levels and asthma susceptibility in three genetically diverse populations.
A recent Université Laval study reveals that omega-3 intake during the last months of pregnancy has a positive impact on an infant's sensory, cognitive, and motor development. The study found a strong correlation between DHA concentration in umbilical cord blood and infant visual acuity and cognitive development.
Researchers discovered that atypical antipsychotic drugs like olanzapine can disrupt energy metabolism in male rats, leading to increased blood sugar levels and abdominal fat storage. The study suggests that these changes may occur earlier than previously thought and could have implications for human health.
Researchers found that a common asthma medication can improve smell function in individuals with biochemistry-based hyposmia. The study used 369 participants and showed significant improvements in over 70% of patients, with no correlation between blood levels and treatment efficacy.
A new blood test, NuroPro, measures 59 protein biomarkers to distinguish between Parkinson's, Alzheimer's and other neurodegenerative diseases. The test has been welcomed by researchers but larger studies are needed to confirm its effectiveness.
Scientists report proteins in alligator blood may provide powerful new antibiotics to combat diabetic ulcers, severe burns, and antibiotic-resistant infections. Additionally, experts foresee 10 years of R&D to make solar energy competitive with petroleum.
A UCI-led study found that coronary calcium detection is a significant predictor of heart attack and disease for diverse groups. The non-invasive procedure uses CT scanning to detect calcium deposits in coronary arteries, which can be valuable for promoting overall cardiac health.
Researchers developed a technique to extract small amounts of hemolymph from fruit flies, which could expedite understanding of neural physiology and disease mechanisms. The new method is more efficient and precise than traditional methods, allowing for individual organism analysis.
A study published in Neurology found that Hispanics with even small amounts of plaque build-up in the carotid artery are up to four times more likely to suffer or die from a stroke or heart attack. The study also highlights the importance of measuring plaque thickness by ultrasound as a simple tool for guiding stroke prevention therapies.
In a phase II trial, patients with varicose veins treated with Varisolve foam experienced no neurological, visual or cardiac changes. The study used carbon dioxide-based foam and monitored patients with heart defects for potential risks.
A reliable blood test for Parkinson's disease could revolutionize care and research, according to a new study. The test uses a 'metabolomic profile' to identify unique changes in dozens of small molecules in serum that are linked to the disease.
A large-scale study published in the American Heart Association rapid access journal report found that cigarette smoking is a significant predictor of stroke in Chinese men. Researchers analyzed data from over 170,000 participants and found that smokers were 2-3 times more likely to suffer an ischemic stroke compared to never-smokers.
The NHLBI has published its first US clinical practice guidelines for von Willebrand Disease, a condition that affects 1 in 100 to 1,000 people. The guidelines provide recommendations for screening, diagnosis, and treatment of the three major types of VWD, emphasizing proper diagnosis and treatment to prevent complications.
A new study by researchers at the University of Illinois Chicago has identified a crucial enzyme for bacterial growth in blood, offering a potential target for antibiotics. The study found that most E. coli bacteria strains cannot grow in human blood if they lack a specific gene involved in nucleotide biosynthesis.
A new approach identifies five genes involved in myelination and six genes involved in growth factor signaling as potential biomarkers for high and low mood states. The study suggests that blood biomarkers may offer an informative window into brain functioning and disease state.
A study examining long-term outcomes following blood clots found that patients with pulmonary embolism are at higher risk of experiencing recurrent clotting, major bleeding episodes, or death. The research also highlights the need for better anticoagulation strategies to reduce complications in the community setting.
Researchers at Indiana University School of Medicine have isolated biomarkers in the blood that identify mood disorders, providing an objective tool for diagnosing and assessing the severity of illness. The discovery may alter the way bipolar illness is diagnosed and treated, offering a new approach to psychiatric treatment.
Scientists at the University of Leicester have developed new Doppler ultrasound techniques to detect emboli, reducing intra-operative and post-operative stroke rates by 96% and 99.3%, respectively. The 30-day death/stroke rate has also fallen from 6% to 2.6%.
A new portable detection system developed by PNNL can accurately detect toxic lead and other heavy metals in blood, urine, and saliva samples. The device is field-deployable, battery-operated, and provides quicker results than current state-of-the-art mass spectrometry systems.
A new study found that vehicle interlocks significantly reduce DWIs among first-time offenders, with a 60% lower risk of repeat offenses. This economic benefit is substantial, saving $3 for every dollar spent on interlocks.
Crocodilians divert blood through a special vessel called the left aorta to bypass their lungs during digestion. This unique system enables them to secrete gastric acid at an unprecedented rate, facilitating digestion and survival. By shunting CO2-rich blood straight to the stomach, crocodilians maintain optimal digestive conditions.
Researchers identify genetic mutations in MTHFR and Factor V as significant contributors to blood clots and tissue injury in the placenta. These mutations may lead to increased risks of preterm birth, intrauterine growth restriction, and preeclampsia.
A collaborative analysis of 18 prospective studies found no link between circulating sex hormones and prostate cancer risk. High levels of male sex hormones were previously thought to be a risk factor, but the results indicate that testosterone and estrogen do not play a significant role in prostate cancer development.
A novel treatment for DVT uses a fiber-binding agent to clear clots rapidly and safely, with 90% of patients experiencing complete resolution of symptoms after six months. The therapy reduces the risk of bleeding and post-thrombotic syndrome, enabling patients to resume normal activity within a week.
Researchers found that carbon nanotubes leave the body primarily through the feces, with some by way of the urine. The study also allays worries that the nanotubes would prove toxic to mice, as none died or showed any anomalies in blood chemistry.
Scientists at the University of Cambridge highlight a strong correlation between persistent organic pollutants (POPs) and insulin resistance, leading to adult-onset diabetes. Research suggests that individuals with high POPs levels in their blood are more at risk of developing type 2 diabetes, even if they are thin.
Researchers at the University of Arizona have discovered a complex metabolic pathway in mosquito species, which they aim to disrupt with a harmless molecule. This could lead to an insecticide that kills both mosquitoes and their eggs, slowing the spread of diseases like malaria and yellow fever.
A study of 2,471 patients with venous thrombosis found a three-fold greater relative risk associated with minor leg injuries that don't require surgery or extended bed rest. These injuries may increase blood clotting risk due to reduced activity and damage to blood vessel walls.
A year-long clinical trial found that vitamin D2 supplements reduced the risk of falls by 19% among women with low blood vitamin D levels and a history of falling. The therapy was most effective in reducing the risk of single falls during winter and spring, but not multiple falls.
Researchers at the University of Alberta have discovered a way to reduce LDL, the so-called 'bad' cholesterol, in the blood by manipulating an enzyme. This finding could lead to new treatments for Type 2 diabetes and heart disease related to obesity.
Researchers developed ceramic hybrid needles using two-photon polymerization, creating microneedles resistant to breakage. The new technology enables efficient drug delivery and minimizes trauma during injections.
A new gene variant has been found to be more common in people with cerebral venous thrombosis than in healthy individuals. The study, published in Neurology, suggests that testing for this gene and using blood thinning medication may help prevent future blood clots.
Researchers found that high blood folate levels can increase homocysteine and methylmalonic acid in individuals with vitamin B12 deficiency, worsening symptoms. This study suggests that excessive folate may compromise the body's ability to use vitamin B12 effectively.
Researchers at Duke University Medical Center have identified four blood proteins that can distinguish patients with lung cancer from those without. The blood test, which uses a classification tree to sort out likelihoods, shows promise as a less-invasive follow-up for patients with suspicious lesions.
A new heart test has been developed to detect mild degrees of heart injury, enabling doctors to identify patients most likely to benefit from life-saving treatments. The test, which searches for a specific protein in the blood, could lead to fewer unnecessary hospital admissions and improved diagnosis.
A study by Yale researchers suggests that YKL-40 may play a role in severe asthma, with elevated levels correlating to increased inflammation and lung function. The discovery brings hope for developing a blood test to identify patients with severe asthma, which affects 2.5 million Americans.
A new study found that experienced ultrasound examiners can accurately classify ovarian tumors using pattern recognition, outperforming blood test CA-125 levels. The method could improve diagnosis and treatment for women with ovarian cancer.
A study of 454 patients with chronic-phase CML taking imatinib for over six years found a high estimated six-year survival rate of 76 percent and strong correlation between overall survival rates and cytogenetic response. The incidence of serious side effects was low, with no long-term new toxicities observed.
Researchers found that ABO-incompatible infant heart transplantation is as safe as transplantation with compatible blood group types. The study suggests that this procedure could significantly reduce the number of infants who die while waiting for a donor heart, with mortality rates potentially decreasing by up to 20%.
Research in Zanzibar, Tanzania found a remarkable fall in children dying from malaria, with deaths among the islands' children dropping to a quarter of the previous level. The achievement follows the introduction of improved treatment and the implementation of widespread use of insecticide-treated mosquito nets.
Researchers found that each year as people age, the time it takes for their heart muscles to squeeze and relax grows longer. The actual amount of blood pumped out by the heart fell by 8 milliliters per year. This decline occurred despite an increase in another standard measure of heart function.
An international panel of researchers developed guidelines to prevent and treat venous thromboembolism, a deadly complication of cancer. The new guidelines recommend the use of anticoagulants in hospitalized cancer patients and suggest treating blood clots for at least six months afterwards.
Researchers from Imperial College London found that people with medium levels of HIV in their blood are the most likely to spread the virus. They can remain asymptomatic for six to eight years before progressing to AIDS, infecting multiple sexual partners during this time.
MIT scientists propose that blood modulates how neurons process information and regulate brain activity. Blood flow affects the activity of nearby neurons, changing how they transmit signals and hence regulating information flow throughout the brain.
A new study found that folic acid supplements can dramatically lower blood arsenic levels in individuals chronically exposed to arsenic-contaminated drinking water. The study, funded by the National Institute of Environmental Health Sciences, showed a 14% reduction in total blood arsenic levels in Bangladesh.
A study published in the American Journal of Clinical Nutrition found that folic acid supplements can dramatically lower blood arsenic levels by up to 14 percent. Folate deficiency is common in Bangladesh, where the study was conducted, and supplementation enhanced detoxification of arsenic.
A new technique developed by UC radiologists uses multi-detector computed tomography (CT) scanners to capture images of chest veins. This approach allows for better diagnosis of venous diseases by compensating for the extra time it takes contrast solution to reach the veins.
A new version of the colon cancer screening test effectively detects colorectal cancer and may replace the current unrehydrated guaiac test. The fecal immunochemical test had a sensitivity of 81.8% for detecting colorectal cancers, outperforming the guaiac test's 64.3% sensitivity rate.
A University of California, Irvine study found children with type-1 diabetes exhale higher concentrations of methyl nitrates when hyperglycemic. The researchers developed a breath device that can warn diabetics of high blood sugar levels and the need for insulin.