Articles tagged with Blood
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that high blood folate levels can increase homocysteine and methylmalonic acid in individuals with vitamin B12 deficiency, worsening symptoms. This study suggests that excessive folate may compromise the body's ability to use vitamin B12 effectively.
Researchers at Duke University Medical Center have identified four blood proteins that can distinguish patients with lung cancer from those without. The blood test, which uses a classification tree to sort out likelihoods, shows promise as a less-invasive follow-up for patients with suspicious lesions.
A new heart test has been developed to detect mild degrees of heart injury, enabling doctors to identify patients most likely to benefit from life-saving treatments. The test, which searches for a specific protein in the blood, could lead to fewer unnecessary hospital admissions and improved diagnosis.
A study by Yale researchers suggests that YKL-40 may play a role in severe asthma, with elevated levels correlating to increased inflammation and lung function. The discovery brings hope for developing a blood test to identify patients with severe asthma, which affects 2.5 million Americans.
A new study found that experienced ultrasound examiners can accurately classify ovarian tumors using pattern recognition, outperforming blood test CA-125 levels. The method could improve diagnosis and treatment for women with ovarian cancer.
A study of 454 patients with chronic-phase CML taking imatinib for over six years found a high estimated six-year survival rate of 76 percent and strong correlation between overall survival rates and cytogenetic response. The incidence of serious side effects was low, with no long-term new toxicities observed.
Research in Zanzibar, Tanzania found a remarkable fall in children dying from malaria, with deaths among the islands' children dropping to a quarter of the previous level. The achievement follows the introduction of improved treatment and the implementation of widespread use of insecticide-treated mosquito nets.
Researchers found that ABO-incompatible infant heart transplantation is as safe as transplantation with compatible blood group types. The study suggests that this procedure could significantly reduce the number of infants who die while waiting for a donor heart, with mortality rates potentially decreasing by up to 20%.
Researchers found that each year as people age, the time it takes for their heart muscles to squeeze and relax grows longer. The actual amount of blood pumped out by the heart fell by 8 milliliters per year. This decline occurred despite an increase in another standard measure of heart function.
An international panel of researchers developed guidelines to prevent and treat venous thromboembolism, a deadly complication of cancer. The new guidelines recommend the use of anticoagulants in hospitalized cancer patients and suggest treating blood clots for at least six months afterwards.
Researchers from Imperial College London found that people with medium levels of HIV in their blood are the most likely to spread the virus. They can remain asymptomatic for six to eight years before progressing to AIDS, infecting multiple sexual partners during this time.
MIT scientists propose that blood modulates how neurons process information and regulate brain activity. Blood flow affects the activity of nearby neurons, changing how they transmit signals and hence regulating information flow throughout the brain.
A new study found that folic acid supplements can dramatically lower blood arsenic levels in individuals chronically exposed to arsenic-contaminated drinking water. The study, funded by the National Institute of Environmental Health Sciences, showed a 14% reduction in total blood arsenic levels in Bangladesh.
A study published in the American Journal of Clinical Nutrition found that folic acid supplements can dramatically lower blood arsenic levels by up to 14 percent. Folate deficiency is common in Bangladesh, where the study was conducted, and supplementation enhanced detoxification of arsenic.
A new technique developed by UC radiologists uses multi-detector computed tomography (CT) scanners to capture images of chest veins. This approach allows for better diagnosis of venous diseases by compensating for the extra time it takes contrast solution to reach the veins.
A new version of the colon cancer screening test effectively detects colorectal cancer and may replace the current unrehydrated guaiac test. The fecal immunochemical test had a sensitivity of 81.8% for detecting colorectal cancers, outperforming the guaiac test's 64.3% sensitivity rate.
A University of California, Irvine study found children with type-1 diabetes exhale higher concentrations of methyl nitrates when hyperglycemic. The researchers developed a breath device that can warn diabetics of high blood sugar levels and the need for insulin.
Scientists have developed a method to detect circulating tumour cells (CTCs) in blood before and after chemotherapy treatment, potentially identifying patients at risk of cancer recurrence. The study found that CTCs persisted in the blood of patients who were more likely to experience recurrence.
Exposure to particulate matter in mice triggers lung macrophages to produce IL-6, leading to accelerated blood clotting and thrombus formation. Targeting IL-6 may decrease the risk of heart problems caused by air pollution.
Researchers discovered that female Evarcha culicivora spiders prefer larger mates before mating, despite the risk of cannibalism. Once mated, females opt for smaller males, a finding that challenges traditional assumptions about spider mating behaviors.
Researchers have identified a pattern of fetal mRNAs detectable in pregnant women's blood, which could serve as a baseline for diagnosing genetic diseases. This detection method has the potential to replace invasive prenatal procedures, offering a new approach to monitoring fetal health.
Researchers at UT Health Science Center have developed a smart particle insulin release system that detects blood sugar spikes and releases insulin to counteract them. The system, which consists of a blood sugar sensing protein and liposomes loaded with insulin, stabilized blood sugar levels in animal models for up to six hours.
Researchers discovered that first-degree relatives of PBC patients have a higher prevalence of anti-mitochondrial antibodies, a biomarker indicative of the disease. This finding enables early screening and assessment of high-risk family members through simple blood tests, potentially leading to better outcomes for PBC patients.
Researchers at the Salk Institute have identified TORC2 as a crucial biochemical control point linking feeding, insulin, and elevated blood sugar production in the liver. The study found that insulin turns off the CREB/TORC2 switch during feeding, highlighting potential drug targets for type II diabetes treatment.
Researchers developed an improved dosing formula for warfarin that takes into account genetic variations in VKORC1 and CYP2C9 genes. This approach enables faster and more accurate estimation of the optimal warfarin dose, cutting dosage changes and potentially increasing patient safety.
A new study published in the Journal of Experimental Medicine suggests that COX-2 inhibitors like Vioxx trigger life-threatening side effects by stimulating blood clotting. The researchers propose a solution by administering TF-reducing drugs alongside Cox-2 inhibitors to treat people safely
Researchers developed a genetic dosing model to predict optimal warfarin dose for patients undergoing orthopedic surgery. The model combines genotype information with clinical factors to estimate therapeutic dosage.
Researchers at OHSU demonstrate a new technique using contrast-enhanced ultrasound and targeted microbubbles to detect inflammatory processes leading to atherosclerosis. This could enable early detection and prevention of coronary heart disease and stroke, two of the nation's most lethal diseases.
Researchers at Boston Medical Center are developing a computerized workstation called Louise to electronically prepare discharge plans for patients. Preliminary research shows that interventions using this technology can reduce inappropriate readmissions and increase patient satisfaction.
Researchers found that restricting blood flow in the arm before coronary artery bypass graft surgery reduced troponin T levels by 43%. This technique, known as remote ischaemic preconditioning, may help protect the heart from injury during surgery. The study's implications for clinical practice are considered immense.
Researchers found a blood protein, IGFBP-1, linked to obesity and exercise aversion may indicate increased pancreatic cancer risk. The study suggests lifestyle factors modifiable for improved prognosis.
Researchers found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients with primary systemic light chain (AL) Amyloidosis. The median survival for all 80 patients was 57 months, with 18 still alive 10+ years after treatment.
A study published in the Journal of the National Cancer Institute found that chemotherapy with bevacizumab increases the risk of blood clots in arteries, with a higher incidence among patients over 65 years old. The risk of arterial thromboembolic events was significantly higher in patients treated with the combination therapy compared...
A University of Minnesota study found that only 37% of the US population is eligible to donate blood, a significant decrease from the previously estimated 177 million. The conventional method overestimated the national pool by 59%, mainly due to factors like chronic diseases and high-risk behaviors.
A new study reveals that only 37% of the US population is eligible to donate blood, with approximately 60 million fewer individuals being eligible than previously thought. The lower donor pool estimate is based on a more stringent model that excludes high-risk individuals and those with chronic diseases.
A study by Johns Hopkins Medicine found that metformin, a widely used diabetes medication, offers distinct advantages over nine other medications in controlling blood sugar levels, weight gain, and bad cholesterol levels. The medication was also found to be less expensive than newer options, with annual treatment costs averaging $100.
A quarter of NYC adult New Yorkers have elevated blood mercury levels, with higher rates among Asian women and those consuming more fish. Pregnant and breastfeeding women, as well as young children, are advised to limit or avoid high-mercury fish to minimize health risks.
A study estimates nearly one-third of hospitalized US patients are vulnerable to VTE, which can lead to dire complications. Researchers stress the need for reinforcing national guidelines and monitoring compliance with hospital protocols for VTE prevention, as well as educating outpatients on preventive measures.
A study of 382 healthy children revealed that over half had low blood levels of vitamin D, with 55% having inadequate levels. Vitamin D deficiency may contribute to bone diseases like rickets and other health issues.
Researchers at the University of California, San Diego discovered that fibrinogen inhibits neural cell growth in spinal cord injuries, leading to paralysis. The study found that fibrinogen's binding to beta 3 integrin receptor and epidermal growth factor receptor prevents axonal growth, which is necessary for regeneration.
Research reveals elevated manganese levels in scrapie-infected sheep's blood before clinical symptoms appear, hinting at a new diagnostic approach. Scrapie-resistant sheep also show increased manganese levels when challenged with the disease.
A large-scale study found that high levels of urate in the blood are strongly associated with a reduced risk of Parkinson's disease. Urate, a normal component of blood, may have beneficial effects due to its antioxidant properties.
Researchers found evidence of two separate networks in the brain that control voluntary behavior, such as reading a word or searching for a star. These networks work independently but toward a common purpose, and understanding their dynamics may aid in treating brain injuries.
Patients hospitalized with bacterial pneumonia face a higher risk of new or worsening heart problems, with nearly 20% experiencing a heart attack or major heart condition. The presence of heart disease significantly increased mortality from pneumonia.
In Denmark, non-invasive screening of pregnant women using ultrasound and blood analysis has reduced the number of children born with Down Syndrome by 50%. The new guidelines have also led to a significant decrease in invasive pre-natal diagnostic procedures, from 11% to around 6% of pregnancies.
Research found that aerobic exercise, such as walking or bicycling, significantly improved ejection fraction and reduced heart size in patients with stable heart failure. In contrast, combining aerobic exercise with strength training showed no similar benefits.
A daily dose of pistachios may improve risk factors for heart disease without weight gain, according to a study published in the Journal of the American College of Nutrition. The pistachio diet led to statistically significant reductions in certain blood lipids and an increase in HDL-C.
A study found that metabolic syndrome is associated with compromised heart structure and function, including symptomatic heart failure. The association was independent of coronary heart disease risk as predicted by the Framingham risk score for diastolic dysfunction, but not systolic dysfunction.
A newly excavated headless skeleton from Nasca, Peru provides important new data on ancient decapitation practices. The analysis suggests that decapitation was part of powerful rituals aimed at ensuring fertility and the continuation of life and rebirth of the community.
Research suggests that people with high levels of inflammation in their blood are more likely to develop Alzheimer's disease. The study of over 600 participants found that those with elevated cytokines were nearly twice as likely to develop the disease.
Researchers have found that monoclonal antibodies from avian flu survivors in Vietnam are effective in preventing infection and neutralizing the virus in mice. The treatment could potentially provide a clinical benefit to humans with H5N1 infections, especially if administered early after symptoms onset.
A large-scale study found that coffee consumption is associated with lower uric acid levels, which appears to be due to components other than caffeine. The researchers suggest that decreased insulin levels and improved insulin sensitivity may contribute to the observed effect.
A meta-analysis suggests that half of blood-thinning drug-related complications can be prevented through improved anticoagulation control. This study highlights the importance of closely monitoring patients taking these medications to avoid serious side effects.
UPMC has started a study using the VentrAssist LVAD, a mechanical blood pump to assist the heart in pumping blood around the body. The study aims to enroll 30 patients for a multi-center feasibility trial to explore its safety and effectiveness as a bridge to transplantation.
Researchers analyzed data on blood donations and recipients in Sweden and Denmark over 34 years, finding no link between cancer risk and blood from precancerous donors. The study provides valuable insights into the safety of blood transfusions and highlights the need for further research on chronic diseases.
A 47-year-old man with congestive heart failure underwent the historic surgery at UPMC, where a beating heart supported by the OCS was successfully transplanted. The patient is doing well after discharge on April 30.
A new animal study investigates three methods of treatment for severe internal injuries, with HBOC-201 resuscitation showing improved survival rates. The study's findings suggest targeting a Mean Arterial Pressure of 80 mmHg is more favorable than a target MAP of 100 mmHg.
A new study validates the Pulmonary Embolism Rule-out Criteria, showing that two-thirds of patients with a low probability of pulmonary embolism receive unnecessary tests. The protocol uses clinical criteria to rule out clots in the lung, reducing costs and side effects associated with CT scans.
Researchers found that pistachio amounts of 1.5 ounces reduced LDL cholesterol levels by 11.6% and total cholesterol by 8.4%, while the higher dose showed significant reductions in lipoprotein ratios. Pistachios also increased antioxidants in the blood, which may help reduce inflammation.
Researchers found that succimer chelation therapy improved postural balance by 6 percent and moving tasks by 19 percent in lead-exposed children. The therapy was effective in reducing lead levels in the blood but also showed benefits on neuromotor abilities.