Research on blood and what it reveals about health. Covers blood biomarkers, occupational exposure, cell-preservation for CAR-T therapy, and blood supply.
A large study found that early surgery does not reduce deaths and disability in patients with brain hemorrhage. Only patients with small blood clots near the surface of the brain may benefit from surgical intervention.
Researchers found that indirect CT venography increases the detection rate of thromboembolic disease by 20% compared to traditional CTPA. The addition of CTV improves diagnosis for patients with pulmonary embolism and deep vein thrombosis, saving lives.
A new study shows that exercise improves three measures of heart protection in postmenopausal women, including better blood clotting profiles and reduced blood clot activation. Regular physical activity may help prevent the formation of blood clots, leading to a lower risk of heart attacks.
Researchers used Mendelian randomization to investigate the link between homocysteine levels and stroke risk. They found that individuals with a specific genetic variation had higher homocysteine levels and increased stroke risk, suggesting a potential role for folic acid and B vitamins in preventing strokes.
A new study suggests that rotary blood pumps may be effective in children with heart failure, potentially saving thousands of lives by sustaining heart function until recovery or transplantation. Researchers believe the technology has the potential to improve treatment outcomes for pediatric patients.
A new analysis found that heavy alcohol drinking was associated with an increased risk of ischemic stroke in men. Moderate drinking of red wine, on the other hand, was linked to a lower risk of stroke compared to other forms of alcohol consumption.
A new study links higher MBL protein levels to reduced risk of heart attack, particularly in individuals with diabetes. The protein's role in clearing oxidized cholesterol from arteries may be a key factor.
Researchers found that a combination of thalidomide and dexamethasone is as effective as standard intravenous chemotherapy in treating newly diagnosed multiple myeloma. A newer analog, CC-5013 (lenalidomide), showed promise with fewer side effects.
A recent study published in Journal of Agricultural and Food Chemistry found that drinking pomelit juice daily can lower LDL blood cholesterol and increase antioxidant activity. Hypercholesterolic patients may benefit from adding fresh Sweetie juice to their diet as a preventative measure against future heart disease.
Adults with diabetes have experienced a 50% reduction in the rate of incident CVD, while those without diabetes saw a 35% reduction. Patients with diabetes have benefited from similar declines as those without, with substantial room for further progress to reduce high CVD event risks.
Researchers found that alcohol impairs brain areas controlling motor functions, leading to increased speeding and crashing. Brain regions involved in decision-making and working memory were not affected until drivers reached a blood alcohol level of 0.08.
Researchers found that ultrasound therapy increased clot clearance by 26% compared to tPA alone, with 70% of patients experiencing complete or partial clearance. The study used a hand-held extracranial ultrasound device to deliver heavy doses of the clot-busting drug tPA directly to blood clots.
Researchers found that statins decrease abnormalities associated with antiphospholipid antibodies, which can cause recurring blood clots. Statins may provide an alternative therapy to warfarin for patients with aPL.
A study published in JAMA found that metabolic syndrome is associated with poor cognitive outcomes in elderly individuals. Participants with the metabolic syndrome and high inflammation showed a significant increase in cognitive impairment and four-year decline in cognitive testing scores compared to those without the metabolic syndrome.
Researchers found that patients' neuromotor functions, including problem-solving and motor skills, significantly declined after cancer treatment but recovered within a year. Factors such as chemotherapy type and immune suppressant use lowered the risk of impaired function.
Loyola is conducting a clinical trial using a blood substitute in trauma patients to increase oxygen delivery and improve survival rates. The study aims to compare the survival rate of patients receiving the blood substitute to those receiving saline solution.
A new clinical trial has found that high skin sterol levels are associated with an increased risk of heart disease in patients with coronary artery disease. The study, published by IMI International Medical Innovations, used a prospective registry to examine the relationship between skin sterol and cardiovascular risk factors.
A study by Emory University researchers found that brief reductions in blood oxygen levels during critical brain development can lead to long-lasting deficiencies in dopamine release and hyperactivity in juvenile rats. This discovery may help explain the development of ADHD and provide insights into potential treatments.
Researchers at Duke University Medical Center have created a novel drug-antidote strategy that provides greater control of drug action. The breakthrough enables the development of matched drug-antidote pairs at the beginning of the drug development process, allowing for more precise treatment.
The Stanford cooling tool uses a local subatmospheric pressure environment to cool the body from the inside out, reducing recovery time after anesthesia. By extending endurance in hot environments, the device has significant implications for athletes, military personnel, and factory workers.
A study finds that 50% of patients with Crohn's disease have viable MAP in their blood, suggesting a systemic infection. The findings raise questions about the role of MAP in IBD and highlight the need for further research to clarify its significance.
A study of healthy individuals aged 60-64 found a significant relationship between high homocysteine levels and changes in deep white matter hyperintensities in the brain, which may be related to mild cognitive impairment. However, HCY levels were not associated with brain atrophy.
The majority of kidney transplant candidates waiting for kidneys have blood type O and are forced to wait even longer for a deceased donor kidney when list-paired exchanges are permitted. Researchers propose limiting these exchanges to pairs with compatible blood types to make them a moral option.
The research project aims to identify tick genes that spread serious illnesses, such as Lyme disease. By analyzing the genome data, scientists hope to develop vaccines to block transmission of microbes that cause tick-borne illnesses.
A new study has found that patients with high levels of circulating tumor cells in their blood have shorter progression-free survival and overall survival rates compared to those with low levels. The presence of these cells can predict prognosis more accurately than other factors, allowing for more tailored treatment decisions.
A nationwide study shows that nucleic acid-amplification testing (NAT) significantly reduces the risk of HIV-1 and HCV infections in blood recipients. NAT detects viral genes earlier than antibody tests, allowing for faster identification and disposal of infected donations.
A new study found that wearing below-the-knee elastic compression stockings every day reduces the incidence of DVT complications from 49% to 26% and severe complications from 12% to 3.5% after a blood clot in two years. The study suggests that stocking therapy should be routine after a deep-vein blood clot.
A study by University of Toronto researchers found high levels of mercury in sport-fish eaters' blood, particularly among Asian-Canadians. The findings emphasize the need for ongoing surveillance and education to minimize health risks from contaminated fish consumption.
The Emory University Health Sciences Center, AABB, and Red Cross will work together to reduce HIV transmission in developing countries by improving blood supply systems, testing for HIV, and creating safe transfusion centers.
A new study suggests that a stroke-prevention strategy for kids pioneered at MCG is working. The program, which involves regular blood transfusions and screening using transcranial Doppler, has led to an 80% decline in strokes among California children with sickle cell disease.
Research found that infants with higher maternal DHA levels at birth showed more mature attentional development and were less distractible during play. This suggests a potential link between DHA supplementation during pregnancy and improved infant cognitive functions.
Researchers found that using growth-hormone-releasing hormone (GHRH) therapy can increase normal growth hormone production and regulation in men with HIV lipodystrophy. This approach resulted in improved body composition, reduced fat deposits, and better cardiovascular health outcomes.
A study found that American ginseng reduced the anticoagulant effect of warfarin in healthy volunteers. Additionally, researchers observed that only 57% of doctors followed standard hand hygiene practices, with factors such as high workload and risk for cross-transmission affecting compliance.
Researchers found that daily doses of ginseng significantly reduced the anti-clotting effect of warfarin, a common blood-thinner medication. The study suggests that substances within ginseng may enhance the function of enzymes that break down warfarin.
Researchers have identified a potential biomarker for ovarian cancer using a blood test that accurately predicts the presence of the disease in 93% of cases. The study suggests that lysophospholipids, found in high levels in most ovarian cancer patients, may be used to develop an early detection strategy for this devastating disease.
Researchers found that an extract from Opuntia ficus indica (prickly pear fruit) reduced nausea, dry mouth, and loss of appetite in young adult volunteers. The study also showed a moderate reduction in hangover symptom severity, with higher levels of C-reactive protein associated with placebo treatment.
Regular cardiac monitoring and prompt treatment can prevent and reverse severe heart dysfunction in thalassemia major patients. The study found that intensive deferoxamine mesylate treatment significantly improved survival rates among those who complied with therapy.
Researchers genetically modified mice to lack the CT or PEMT pathways, resulting in significant reductions of lipoproteins and homocysteine levels. This suggests pharmacological inhibition of PC manufacture in the liver as a potential approach to lower LDL cholesterol and homocysteine levels.
Researchers found that high levels of lead and cadmium in adults were associated with a 2.8 times greater risk of developing peripheral arterial disease (PAD). Smoking was also found to increase the risk of PAD, possibly due to cadmium's damage to blood vessel linings.
Research found that adults with high blood concentrations of lead or cadmium were almost three times more likely to develop peripheral artery disease, a condition similar to coronary artery disease. The study suggests that low-level exposure to these metals may be problematic in terms of cardiovascular disease risk.
A study of 2,125 adults found that those with the highest blood concentrations of lead or cadmium were almost three times more likely to develop PAD. The highest levels of the two metals were well within what is currently considered safe levels.
Perfusion CT scans can reveal how much blood is present in the brain and how quickly it's moving, helping doctors decide on treatments such as surgery or clotbuster drugs. The technique has shown promise in assessing patients with stroke or carotid artery issues, potentially improving treatment outcomes.
A new study found that D-dimer tests can eliminate the need for CT angiograms of the lungs in 60% of cases, where the result is negative. The test measures the amount of D-dimer in blood, a breakdown product of fibrin, which forms blood clots.
Loyola Medicine is conducting a clinical trial testing a new oxygen-carrying blood substitute for trauma patients. The study aims to compare the survival rate of patients receiving the blood substitute with those receiving saline solution. Community outreach efforts have been made to inform the public about the trial.
New global trials build on earlier phase III studies demonstrating FOSRENOL's efficacy in treating hyperphosphataemia. The new trials aim to confirm safety and efficacy of the phosphate binder, which has shown lower incidence of hypercalcaemia compared to calcium-based binders.
A study reveals that anti-clotting treatment is underused at many hospitals in the US, with significant differences between academic and community hospitals. The American Heart Association's Get With The Guidelines program aims to bridge this gap and simplify patient care.
Researchers found a significant association between high blood testosterone levels and an increased risk of prostate cancer in older men. The study, which followed over 3,000 men for 40 years, also showed that the protein sex hormone-binding globulin (SHBG) was associated with a slightly decreased risk for prostate cancer.
A clinical trial of 370 patients found that Pfizer's VFEND was as effective as the two-drug standard of amphotericin B and fluconazole in treating Candidemia. The treatment successfully cleared Candida from the blood, with a response rate of 41% at 12 weeks.
A study found MRI to be highly useful in the evaluation of patients with uterine fibroids. The imaging technique offers advantages over sonography, including a larger field of view and better contrast resolution. MRI can help identify subsets of patients who may not benefit from UAE treatment, allowing for more personalized care.
MDCT angiography has been shown to accurately demonstrate filling defects in the superior mesenteric artery and its branches. The study found that MDCT angiography enabled correct diagnosis of acute mesenteric ischemia in 10 out of 41 patients, providing alternative diagnoses for 19 remaining cases.
A study of 160 pregnant women with genetic risk factors for thrombophilia found that enoxaparin significantly reduced pregnancy loss compared to low-dose aspirin. Women taking enoxaparin had a normal live birth rate of 86% and healthy newborns, while those on aspirin suffered more pregnancy losses.
Research found a direct correlation between viral levels in blood and semen, with acutely infected individuals being hyper-infectious before symptoms occur. Transmission rates during heterosexual sex are likely to be much higher than previously thought during this period.
A new bio-bar-code amplification test could provide a comprehensive disease profile from a single drop of blood, making it ideal for resource-poor settings. The test has already shown promise in detecting anthrax and prostate cancer, with the potential to be ready for marketing within one year.
Research found a 50% increased risk of total stroke and 70% increased risk of ischemic stroke in women with migraine with aura, compared to those without. High cholesterol levels were also associated with an increased risk of ischemic stroke.
Duke researchers found that slower rewarming reduces brain temperature and hyperthermia risks after coronary artery bypass surgery. This leads to improved cognitive outcomes for patients six weeks post-surgery. A seven-year analysis of 6,334 patients showed significant reductions in hyperthermic episodes.
Researchers found that black women with high blood pressure during pregnancy had the highest homocysteine levels, while white women had lower levels. The study suggests increasing folic acid intake among blacks to mitigate this risk. Homocysteine levels are influenced by diet and genetic factors.
Scientists create microscision technique that uses gas to bombard skin with tiny crystals, creating invisible conduits for drug delivery. The new method is shown to be effective in administering local anaesthesia without causing pain, making it a promising alternative to traditional needles.
Researchers are cloning mosquito genes to understand the hormone-controlled mechanism of diuresis, a fast process by which mosquitoes excrete waste. This study aims to develop new, selective insecticides targeting the hormone receptor, potentially controlling vector-borne diseases like dengue fever.
According to a study, only 15% of stroke patients arrive at the hospital within three hours of symptom onset. This leads to a low rate of IV tPA use, which is critical for dissolving blood clots and restoring blood flow. The researchers found that shortening ED arrival times could significantly increase IV tPA use in the US.
A new study found that taking DHEA, a hormone supplement popular among athletes, does not increase testosterone levels but boosts other harmful hormones associated with prostate growth. Researchers tested 12 healthy men and found increased levels of byproduct hormones that may be bad for the prostate.