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Sleep and stress give clues to understanding epileptic seizures - study

A recent study discovered two subgroups of people with idiopathic generalized epilepsy, one experiencing highest incidence during sleep and the other during daytime. The researchers found that either dynamics of cortisol or sleep stage transition explained most of the observed distributions of epileptiform discharges.

SourceUniversity of Birmingham·JournalPLOS Computational Biology·TypeData/statistical analysis·DateOct 17, 2023

Study examines role of working memory, cognitive functions in English learners learning to write

Researchers found that working memory was the most significant predictor of writing ability among English learner students. Cognitive functions such as phonological awareness and oral language development were also important, but only working memory consistently predicted higher scores in writing.

SourceUniversity of Kansas·JournalJournal of Experimental Child Psychology·TypeExperimental study·DateOct 17, 2023

Smarter CT scans may approach the level of MRI

A new method using deep learning can provide as much information from brain images taken with CT as images captured with MRI, enhancing diagnostic support for conditions like dementia and other brain disorders. The software has been trained on 1,117 people and shows promise in diagnosing normal pressure hydrocephalus.

SourceUniversity of Gothenburg·JournalAlzheimer s & Dementia·TypeImaging analysis·DateOct 17, 2023

Penn Medicine researchers identify the link between memory and appetite in the human brain to explain obesity

Researchers found that individuals with higher body mass indexes have impaired connections between the hippocampus and hypothalamus, leading to an inability to control eating habits. The study suggests that targeting this brain circuit may lead to new treatments for obesity and related disordered eating conditions.

SourceUniversity of Pennsylvania School of Medicine·JournalNature·TypeRandomized controlled/clinical trial·DateAug 30, 2023

How psychedelic drugs affect a rat’s brain

Researchers at Lund University discovered that psychedelic substances LSD and ketamine cause simultaneous synchronisation of neurons in several brain regions. This phenomenon is linked to the psychedelic experience and may hold clues for understanding psychoses and consciousness.

SourceLund University·JournalCommunications Biology·DateAug 8, 2023

Nerve cells in the brain can halt all movement in the body – even breathing

Researchers have discovered a group of nerve cells in the midbrain that can completely stop all forms of movement and slow down breathing and heart rate when stimulated. The study provides valuable insight into how the nervous system controls movement and may help understand Parkinson's disease.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalNature Neuroscience·TypeExperimental study·DateJul 27, 2023

Cell-to-cell diversity is key to protecting brain from neurological diseases: University of Ottawa research

A University of Ottawa study reveals that a diverse brain's ecosystem is key to maintaining normal function while responding to changes. This concept is inspired by Charles Darwin's idea that biodiversity is crucial for survival, suggesting cell-to-cell diversity helps prevent failures in brain circuits.

SourceUniversity of Ottawa·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateJul 18, 2023

Fear is in the eye of the beholder

A cluster of neurons in the brains of fruit flies has been found to control visual aversion to scary objects. The researchers discovered that these neurons release a chemical called tachykinin, which regulates vision when feeling afraid.

SourceUniversity of Tokyo·JournalNature Communications·TypeExperimental study·DateJul 13, 2023

New brain circuit for epilepsy uncovered

A new study by investigators from the Brigham and Women’s Hospital found that lesions associated with epilepsy are connected to a common brain network, suggesting the brain connections disrupted by the lesions are key. This discovery may have clinical implications for predicting epilepsy risk and targeting treatments.

SourceBrigham and Women's Hospital·JournalJAMA Neurology·TypeObservational study·DateJul 3, 2023

Brain imaging-based biomarker of depression identified

Researchers used brain imaging to identify multiple subtypes of depression, finding distinct deviation patterns in functional connectivity among brain regions. This study provides leads for developing better treatments and personalized therapeutic interventions.

SourceElsevier·JournalBiological Psychiatry·TypeObservational study·DateJun 27, 2023

How seeing corpses reduces the lifespan of flies

A new study in PLOS Biology found that specific brain cells, R2 and R4 neurons, are activated when flies encounter dead flies, leading to faster aging. This increased activity is linked to the serotonin receptor 5-HT2A, which can potentially be targeted for slowing down human aging.

SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateJun 13, 2023

Discovery of neurons that recognize others

Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.

SourceInstitute for Basic Science·JournalNature Communications·TypeExperimental study·DateJun 1, 2023

New tool may help spot “invisible” brain damage in college athletes

A new study published in The Neuroradiology Journal introduces an artificial intelligence computer program that can accurately identify changes in brain structure resulting from repeated head injury. This AI tool uses machine learning to process magnetic resonance imaging (MRI) scans and distinguish between the brains of male athletes ...

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalThe Neuroradiology Journal·TypeExperimental study·DateMay 30, 2023

Understanding the speed of brain communication

A study by Mayo Clinic researchers found that brain transmission speeds continue to increase into early adulthood, reaching a plateau around age 30-40. This may help clinicians offer therapies to treat disorders such as anxiety and depression that emerge during late adolescence and early adulthood.

SourceMayo Clinic·JournalNature Neuroscience·DateMay 11, 2023

Brain diseases are better classified using analysis of gene activity

Researchers at McGill University found that analyzing gene activity can classify brain diseases into five primary groups, improving diagnosis accuracy. The study identified previously unknown relationships among diseases, such as language development disorders and obsessive-compulsive disorder, which share common genes and cell types.

SourcePLOS·JournalPLOS Biology·TypeObservational study·DateApr 20, 2023

Mind-body connection is built into brain, study suggests

A recent study published in Nature has identified specific brain areas that integrate planning, purpose, physiology, behavior, and movement. Researchers found that stimulating certain areas of the brain can calm both the body and mind, providing new insights into the mind-body connection.

SourceWashU Medicine·JournalNature·TypeExperimental study·DateApr 19, 2023

Early menopause, later start to hormone therapy may increase risk of Alzheimer’s disease

A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...

SourceMass General Brigham·JournalJAMA·TypeObservational study·DateApr 3, 2023

Human Brain Project researchers develop new full-scale 3D structural model of the human hippocampus

Researchers have created a high-resolution, single-cell model of the human hippocampus CA1 area using data from the BigBrain Atlas. The model replicates the structure and architecture of the neurons, as well as their connectivity. This advancement in neuroscience has potential applications for modeling other brain regions.

SourceHuman Brain Project·JournalNature Computational Science·DateMar 24, 2023

Post-bariatric surgery exercise modulates brain regions associated with regulation of food intake

Exercise training after bariatric surgery alters brain networks associated with food intake and energy regulation. The study found that exercise increased connectivity between the hypothalamus and sensory areas, while decreasing links to the default mode network and salience network.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Obesity·DateMar 23, 2023

Progress in unlocking the brain's "code" for depression

Researchers collected electrophysiological recordings from prefrontal cortical regions in three human subjects with severe treatment-resistant depression. They found lower depression severity correlated with decreased low-frequency neural activity and increased high-frequency activity.

SourceElsevier·JournalBiological Psychiatry·TypeExperimental study·DateMar 16, 2023

Repetitive negative thinking during low mood linked to suicidal thoughts – new study

A new study has found that increased rumination is a predictor of greater severity of suicidal ideation in young people with major depressive disorder. The study, published in the Journal of Affective Disorders, suggests that elevated cognitive rumination is associated with lower cortical surface area and suicidal ideation.

SourceUniversity of Birmingham·JournalJournal of Affective Disorders·TypeData/statistical analysis·DateMar 16, 2023

How neuroimaging can be better utilized to yield diagnostic information about individuals

Researchers from Dartmouth and University Medicine Essen found that strong links between brain measures and traits can be obtained when machine learning algorithms are utilized. This approach allows for high-powered results from moderate sample sizes, opening up studies of many traits and clinical conditions previously inaccessible.

SourceDartmouth College·JournalNature·TypeCommentary/editorial·DateMar 14, 2023

Mapping unknown territory

Scientists at Max-Planck-Gesellschaft created an interactive atlas of gene expression in the zebrafish brain, revealing hundreds of genes with single-cell resolution. The new map integrates seamlessly with existing data, providing new insights into neural structure and function.

SourceMax-Planck-Gesellschaft·JournalScience Advances·TypeObservational study·DateMar 1, 2023

Charting a course in the brainy frontier

Kyoto University researchers have created a map comparing circuit structure with neural activity in mammals, revealing a new mechanism behind visual cortex activities. This discovery sheds light on the hidden connections between neurons and could provide directions for constructing power-efficient deep neural networks.

SourceKyoto University·TypeExperimental study·DateFeb 16, 2023

Researchers evidence new characteristics of the extinct American cheetah ‘Miracinonyx’

The study, conducted by the University of Malaga and others, analyzed the skeleton and brain architecture of Miracinonyx trumani, finding that it had retractable claws and was able to grapple with its prey like cougars. Its brain surface also showed differences from cheetahs, suggesting an intermediate form between the two species.

SourceUniversity of Malaga·JournalBiology Letters·TypeExperimental study·DateFeb 15, 2023

Accepting anxiety for peace of mind

A mindfulness-based intervention program significantly decreased subjective anxiety and improved emotional regulation in AN patients. The study found changes in brain regions involved in anxiety, emotion arousal, and self-referential processing.

SourceKyoto University·JournalBJPsych Open·TypeExperimental study·DateFeb 3, 2023