Research on how the brain is built and how it governs body and behavior. Covers neural circuits, sleep, sensory systems, brain structure, and the brain-body connection.
Researchers at Johns Hopkins Medicine found that certain stem cells have built-in tracers made of sugars that can track their movement in living tissues. The discovery could streamline and advance restorative research for diseases of the brain.
A study examining the health records of 37,379 Medicare beneficiaries found that older adults are at the highest risk of stroke within the first three days after COVID-19 diagnosis. Vaccination and other preventive measures can help reduce this risk.
Researchers analyzed data from hospitals in the US, Australia, and New Zealand to compare alteplase and tenecteplase for treating ischemic strokes. The study found that patients treated with tenecteplase had significantly lower rates of serious bleeding into the brain compared to those treated with alteplase.
New research reveals that one in three US stroke survivors experience food insecurity, which can exacerbate cardiovascular disease and stroke risk. Healthcare professionals can play a crucial role in addressing food insecurity by engaging with patients and providing support or resources.
Researchers analyzed data from over 35,000 adults who had no history of stroke or dementia. Those with optimal cardiovascular health showed a 2.4% higher brain volume, equivalent to a 7-year younger brain. Good blood pressure control and healthy blood sugar levels also contributed to healthier brain imaging measures.
Researchers at the University of Pittsburgh have discovered how 'polyglot' neurons encode and decode sensorimotor chatter, enabling the differentiation between motor and sensory signals. This breakthrough has vital applications in brain-computer interfaces and neuroprosthetics, where accurate decoding is crucial.
In young adults, women are at a higher risk of ischemic strokes, with a 44% greater incidence compared to men. Researchers highlight the need for further research into the causes and non-traditional risk factors that contribute to this disparity.
A study published in PLOS Medicine found that reducing air pollution exposure can slow cognitive decline in older women, with benefits seen across various demographics. The research followed 2,232 women for up to 20 years, revealing a significant association between improved air quality and reduced cognitive decline.
Researchers found no notable differences in early hospital arrival time or use of EMS for first-time and recurrent strokes, despite varying patient characteristics. The study highlights the need for more information about stroke signs and symptoms to improve hospital arrival times and reduce disability.
A comprehensive quality-improvement initiative in a NICU reduced death and severe brain bleeding in extremely preterm infants from 27.4% to 15%. The program introduced evidence-based practices, including electronic order sets, improved monitoring of blood carbon dioxide and pH levels, and standardized delivery room practices.
Researchers have developed a system that can capture the information in speech signals similar to how humans perceive speech. The method uses a matching pursuit algorithm and psychoacoustic principles to produce high-quality resynthesized speech signals with natural accents.
Studies using magnetic resonance imaging found a correlation between decreased blood flow in specific brain areas and tinnitus severity. Researchers at the University of Illinois Urbana-Champaign explored these links to better understand the causes of tinnitus.
Nagoya University researchers have discovered how bird brains compute time differences between sounds reaching each ear to determine their location. This process relies on the clustering of nerve junctions in specialized dendrites dedicated to low-frequency sounds.
Researchers developed a single-use sensor strip that can detect cerebrospinal fluid (CSF) leaks, providing a rapid diagnostic tool for patients with brain and spinal cord injuries. The test uses antibodies specific to proteins found in human CSF, detecting leaks even when other substances are present.
University of Maryland School of Medicine researchers have developed a technique to consistently and reproducibly open the blood-brain barrier in mice. This advancement provides a way to better test potential therapeutics for brain cancer, neurodegenerative disorders, and mental illness.
A study led by RCSI researchers found that almost half of tumours with metastatic breast cancer in the brain have changes in DNA repair pathways, making them vulnerable to PARP inhibitor drugs. This discovery opens up potential novel treatment strategies for patients with limited targeted therapy options.
Researchers at KTH Royal Institute of Technology and Stanford University have developed a material that enables the commercial viability of neuromorphic computers mimicking the human brain. The material, MXene, combines high speed, temperature stability, and integration compatibility in a single device.
Scientists have identified hundreds of proteins constantly transported throughout healthy brain cells, offering a new understanding of neurological diseases like Alzheimer's and autism. The discovery reveals how protein transport goes awry in these conditions, paving the way for future research into intercellular communication.
Researchers at University of California San Francisco have catalogued over 40 previously unknown cell types in the human brain's blood vessels. These findings connect hemorrhagic stroke with novel immune cells, offering new targets for therapies.
A new study by WVU researcher William Walker found that the blood-brain barrier is dynamic and more receptive to chemotherapy at night. This could lead to better treatment outcomes for patients with brain metastasis.
Researchers from Karolinska Institutet developed a novel method to diagnose constant tinnitus using auditory brainstem responses (ABR). The study found that people with occasional tinnitus are at increased risk of developing constant tinnitus, while those with existing constant tinnitus are more likely to experience persistent symptoms.
Researchers found that males keep track of the order of their songs and how often each one is sung for up to 30 minutes. This complex behavior allows them to curate both their current playlist and the next one, with variations in song order and repeats.
A recent study found that people with Parkinson's Disease who consume more flavonoids have a lower mortality risk than those who don't. The researchers discovered that higher flavonoid intake is associated with improved survival rates in both men and women, particularly when it comes to anthocyanin-rich foods like berries and red wine.
A new meta-analysis of available literature on ALS disease has identified a group of seven environmental chemicals as correlates with increased risk of developing ALS. Exposure to these chemicals, including BMAA and heavy metals, may be contributing to the disease burden in certain regions.
A UC researcher is leading three projects to study the genetic workings of deadly pediatric brain tumors, including DIPG. The goal is to understand how genes regulate blood vessels and develop more effective treatments. Researchers are also exploring a new drug that targets a specific genetic mutation.
A longitudinal survey of over 3,000 adolescents aged 11-14 found that supportive relationships with family and friends, physical activity, and better sleep helped shield against the pandemic's negative impact on mental health. Girls were more likely than boys to experience psychological distress during the pandemic.
A UCLA-led study found that aducanumab's ancillary care services, such as MRIs and neurologist visits, account for nearly 20% of total Medicare costs. The estimated annual spending on the drug could increase Medicare premiums.
New research reveals the brain's flexibility in multitasking while walking, improving stability and performance. The study uses a Mobile Brain/Body Imaging system to record brain activity while participants walk on a treadmill or perform cognitive tasks.
The Epstein Family Foundation has donated $50 million to USC and UC San Diego to accelerate Alzheimer's research and discover effective therapies for the disease. The collaboration aims to compress study design, patient recruitment, and clinical trials to expedite the discovery of better treatments and a cure.
A Bar-Ilan University study found that participants remembered large images 1.5 times more than small ones, regardless of detail or resolution. This phenomenon may affect screen quality and learning on smartphones, suggesting larger screens could be better for studying.
Young children and babies use saliva sharing as a cue to determine strong relationships and mutual obligations. Research found that babies expect people who share saliva to offer help when distressed, suggesting a vital skill for learning social relationships.
Researchers developed a gene therapy called Targeted Augmentation of Nuclear Gene Output (TANGO), which boosts SCN1A protein production in brain cells. The treatment restored normal cell function and reduced seizures in lab mice with Dravet syndrome, offering hope for the first direct treatment of the fundamental cause.
A Dartmouth study found that people who respond faster to each other in conversations feel more connected. The research, published in the Proceedings of the National Academy of Sciences, used response time data to measure social connection between strangers and close friends.
A new study published in Science reveals distinct filament structures in Alzheimer's disease, with Type I filaments found in sporadic cases and Type II in familial cases. The findings may lead to new prevention and treatment strategies.
A new study published in JNeurosci found that the brain selectively responds to unfamiliar voices during sleep, even when familiar voices are present. This ability allows the brain to strike a balance between resting and being responsive to its environment.
Researchers at RIKEN CBS demonstrate that neural networks minimize energy cost and solve mazes efficiently, pointing to a set of universal mathematical rules. The findings will aid in analyzing impaired brain function and generating optimized neural networks for artificial intelligences.
A recent study published in Psychological Research found that movement can boost creative thinking by providing freedom to make self-determined movements. Small movements while sitting can have the same positive effects as walking, and forced or suppressed movement can hinder cognitive processes like creativity.
Researchers at West Virginia University are investigating the link between chronic stress and Alzheimer's disease using animal models. They aim to understand how xanthine oxidase may sabotage brain blood vessels in Alzheimer's patients, and explore whether a medication can block this pathway to keep the brain healthy.
Researchers have discovered that heart disease causes early brain dysfunction, leading to reduced blood flow and increased risk of dementia. A combination of heart disease and a genetic predisposition for Alzheimer's Disease also trebles the amount of beta-amyloid protein in the brain.
Researchers suggest forgetting memories due to environmental feedback and predictability, rather than decay. This 'natural forgetting' can be beneficial for decision-making and behavior, and may even be reversible in certain circumstances.
A green Mediterranean diet rich in polyphenols and low in red and processed meat may slow age-related brain atrophy. The DIRECT PLUS 18-month trial found significant attenuation of brain atrophy among participants who adhered to both diets.
Research led by Diego Bohórquez at Duke University has identified the cells responsible for sensing sugar in the gut. These neuropod cells produce neurotransmitters that transmit signals to the brain, allowing animals to distinguish between real sugar and artificial sweetener.
A new study found that certain brain wave patterns during sleep can be used to diagnose dementia and other cognitive impairments. The study identified parameters for automated detection methods, which were linked to fluid intelligence and declined during early stages of dementia.
Scientists at the University of Missouri discovered that bisphenol A (BPA) exposure during pregnancy can negatively impact fetal brain development. MicroRNAs in the placenta play a key role in regulating cellular functions, including neural development. Researchers believe that microRNA packages could reach the brain through the placen...
Researchers at Waseda University discovered a new protein isoform called Senp5S, which helps regulate Drp1 and mitochondrial dynamics during brain development. The study suggests a novel and vital role for post-translational SUMOylation in neuronal differentiation.
Researchers at University of Wisconsin-Madison discovered that increasing Nrf2 gene expression in astrocytes protects neurons from Alzheimer's disease progression. Boosting Nrf2 slowed cognitive and physical decline, reduced beta-amyloid accumulation, and reversed genetic changes in mouse models.
A new study found that reducing air pollution can lower dementia risk among older women by decreasing their likelihood of developing dementia. The benefits were consistent despite differences among participants in age, geographic area, socioeconomic background, and other factors.
Researchers have discovered a new biomarker, microstate D, associated with increased sleep disturbance and inattention symptoms in adults with ADHD. The study, published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, provides evidence for a more precise diagnosis of the disorder.
A recent study published in Stroke found that the Woven Endobridge (WEB) device is safe and effective in treating brain aneurysms, with adequate occlusion occurring in 85.7% of cases. The device also showed low rates of blood clot-related complications and no re-ruptures after treatment.
A new UCSF study found that the neural connections of newborns with two different kinds of brain injuries were linked to significantly different developmental outcomes years later. CHD newborns had worse language function at 12-18 months and worse cognitive, language, and motor function at 30 months compared to HIE infants.
New experiments challenge conventional wisdom on neuronal refractory periods, discovering durations exceeding 20 milliseconds and sensitivity to input signal origin. These findings may hold the key to understanding degenerative diseases and advancing artificial intelligence-based applications.
A study published in Neurosurgery found that responsive neurostimulation system reduced disabling seizures in 84% of children and young adults with drug-resistant epilepsy. The youngest patient to undergo RNS implantation was a 3-year-old child.
Researchers found that astronauts with SANS have increased intracranial dural venous volumes, suggesting an association between intracranial venous congestion and SANS. This study provides insight into the effects of gravity on the brain and eyesight in space.
A sustainable diet rich in vegetables and fibre intake may lower the risk of brain bleeding or blood clots. Researchers from Aarhus University found that following Nordic dietary recommendations can lead to a reduced risk of such events, contrary to previous studies suggesting vegetarian diets may be associated with higher risks.
A Tel Aviv University study found a significant link between changes in G-protein-coupled receptors and brain adaptability. Disabling the voltage sensor of these proteins caused uncontrolled brain flexibility, leading to excessive habituation to odors.
A new study reveals that the superior colliculus, a lesser-studied region responsible for saccades and facial recognition, dynamically changes its clustering of neurons depending on the mouse's conscious state. This finding suggests that the brain optimizes visual information processing based on its awake or anesthetized state.
A study published in Science Advances found that high-sucrose diets contribute to brain angiopathy with impaired glucose uptake, leading to psychosis-related higher brain dysfunctions in mice. The researchers created a novel mouse model exhibiting mental disorder-like symptoms after excessive sugar intake at puberty.
A team of researchers found a connection between energy production and Alzheimer's disease in zebrafish with mutated genes. They discovered that Alzheimer's disease affects the use of oxygen within cells to produce energy, leading to severe deficiency in brain function.
Researchers found that CBD shrinks glioblastoma tumors by reducing inflammation and restoring immune balance. The compound also suppresses key proteins involved in tumor growth and spread, making it a potential novel adjunct therapy for glioblastoma patients.
A recent China-wide study investigated the effect of general versus regional anesthesia on post-operative delirium in older adults undergoing hip fracture surgery. The results showed no significant difference in delirium incidence between the two groups, contradicting previous assumptions.