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Study charts origins of fear

A study published in Neuron identifies the pre-frontal cortex as the origin of fear memory, contradicting previous research that linked it to the hippocampus. The researchers found that NMDA receptors play a critical role in developing fear memory, and blocking these receptors can reduce fear response.

SourceUniversity of Toronto·JournalNeuron·DateSep 15, 2005

Decoding the logic of olfaction

The study found that individual odors stimulate a small subset of neurons across a large area in the cortex. Different odorants exhibit similar patterns of activation, but with partial overlaps. This suggests a complex logic to the way information is mapped onto the cortex.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateMay 25, 2005

Choosing where to look – and changing your mind

A study using fMRI reveals separate brain regions for making choices and dealing with conflicts, shedding light on why people with damaged medial frontal cortex struggle with actions and difficult decisions. The findings have implications for understanding human decision-making processes.

SourceCell Press·JournalCurrent Biology·DateJan 25, 2005

Human see, human do

Researchers at UCL found that brain activity increases in areas known as the 'mirror system' when experts view movements they've been trained to perform, compared to non-experts. This fine-tuned system may enable professionals to simulate skills without moving and maintain movement ability despite injury.

SourceUniversity College London·JournalCerebral Cortex·DateDec 21, 2004

Brain imaging reveals new language circuits

A study employing magnetic resonance imaging (MRI) confirms long-held suspicions about the complexity of language processing in the brain. Researchers identified a new language area, dubbed Geschwind's territory, which connects to classical language areas via a separate route, shedding light on the evolutionary origins of language.

SourceWiley·JournalAnnals of Neurology·DateDec 13, 2004

Deciphering an autism mystery

Researchers have identified a specific gene, EN2, that contributes to autism spectrum disorder (ASD). Variations in this gene may affect brain development and behavior. The study also found changes in neurotransmitter systems, including acetylcholine and serotonin, which may disrupt communication between cells.

Newborns have ear preferences, too

Researchers found that newborn babies' right ears are more responsive to speech-type stimuli, while their left ears are more responsive to tonal sounds. This suggests that the auditory system develops differently on each side of the brain from birth.

SourceUniversity of Arizona·JournalScience·DateSep 9, 2004

Researchers identify novel method of distinguishing Alzheimer’s disease from other types of dementia

Researchers at UT Southwestern Medical Center have identified a characteristic sign of Alzheimer's disease that can distinguish it from frontotemporal diseases, which are the second-leading cause of dementia in the elderly. SPECT testing measures brain blood flow and shows significant reductions in the posterior cingulate cortex, indic...

SourceUT Southwestern Medical Center·JournalJournal of Nuclear Medicine·DateMay 5, 2004

The brain's flashy tale

Researchers discovered that the timing of short and long bright light flashes can create optical illusions by activating two parallel pathways in the brain. These pathways adapt to changes in light, suggesting a complex network for handling perception and consciousness.

SourceSalk Institute·JournalNature·DateApr 14, 2004

Storage limits on our visual hard drive

Researchers René Marois and J. Jay Todd found that the human brain's visual short-term memory has a limited storage capacity of about four objects. This is attributed to the posterior parietal cortex, which plays a key role in holding information from visual scenes.

SourceVanderbilt University·JournalNature·DateApr 14, 2004

The human brain and comparative judgments

A new study published in Neuron reveals that the brain processes continuous dimensions such as size and luminance in distributed regions of the cortex. The researchers observed that there is considerable overlap between local brain regions and no single region uniquely selective for one particular stimulus.

SourceCell Press·JournalNeuron·DateMar 24, 2004

Neurons so excited that they just can't hide it

A study found that mice with silenced small-conductance calcium-activated potassium (SK) channels in the DCN had increased firing rates and ataxia. Despite this, Purkinje cell input into the DCN remained intact, indicating a direct relationship between SK channel regulation and proper muscle coordination.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateFeb 16, 2004

What a difference a decade makes

Researchers found that children's brains show different activity patterns in left frontal and extrastriate cortex compared to adults. The study suggests that brain development continues into early school years, with some areas becoming more active in children.

SourceWashU Medicine·JournalScience·DateMay 23, 2002

'Bat-n-man'

Researchers mapped the primary auditory cortex of a pallid bat, revealing insights into the structure and function of its hearing system. The study found that neurons in the low-frequency noise-preferring region are systematically organized with respect to their sensitivity to interaural intensity differences.

SourceAmerican Physiological Society·JournalJournal of Neurophysiology·DateFeb 12, 2002

Imaging pain

Dr. Bushnell's laboratory uses human brain imaging techniques to study pain, finding four key brain regions involved in the experience. Activity in these regions is linked to emotional responses to pain, suggesting that psychological state can alter its perception.