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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Seeing the song

A new Northwestern University study tracked the auditory system's response to highly complex auditory-visual stimuli like music and moving images. The research shows that the left auditory cortex specializes in processing precise timing for sounds and applies this ability to encode auditory-visual synchrony, but only in certain situati...

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Ballet dancers' brains adapt to stop them getting in a spin

Researchers found differences in brain structure between ballet dancers and rowers that enable dancers to suppress signals from the balance organs, allowing them to perform pirouettes without feeling dizzy. This adaptation may help improve treatment for patients with chronic dizziness.

Getting an expected award music to the brain's ears

Researchers studied brain activity in volunteers while they expected and received rewards, finding that the auditory cortex was activated during both scenarios. The findings suggest a broader role for the auditory cortex in processing expectations beyond just sound.

Schizophrenia symptoms linked to faulty 'switch' in brain

Researchers at the University of Nottingham have discovered a faulty 'switch' between brain regions that may cause psychotic symptoms in people with schizophrenia. The study suggests that detecting this disconnection could help identify patients with the condition, and potentially lead to more effective treatments.

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How brain microcircuits integrate information from different senses

A new study published in Neuron sheds light on the complex processes of brain integration, revealing differences in excitatory and inhibitory cells and superficial and deep layers of the cortex. This breakthrough understanding is essential for designing future strategies to stimulate brain repair and re-create precise circuits.

How visual attention affects the brain

Researchers at the University of California, Davis have made a groundbreaking discovery on how visual attention affects brain activity. By measuring signaling through single nerve connections in monkeys, they found that attention increases efficiency and boosts signal strength.

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3-D map of blood vessels in cerebral cortex holds suprises

A team of researchers created a 3D map of blood vessels in the cerebral cortex, revealing unexpected connections that don't align with neural cell organization. The study's findings have implications for functional brain imaging and our understanding of dementia.

Developmental neurobiology: How the brain folds to fit

A novel nuclear protein called Trnp1 triggers the expansion and folding of the cerebral cortex in mice, supporting tangential expansion and ordered formation of neurons. The findings imply that Trnp1 controls both expansion and folding and serves as a starting point for dissecting cellular and molecular interactions.

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Fascinating rhythm: The brain's 'slow waves'

Researchers discovered that brain's 'slow waves' start in the cerebral cortex and are initiated by a local cluster of neurons. This finding provides new insights into processes like memory consolidation and learning, and could lead to a better understanding of diseases like Alzheimer's.

Stanford study shows different brains have similar responses to music

Researchers found a consistent pattern of activity across individuals in several brain structures, including those involved in movement planning, memory, and attention. The study suggests that higher-level centers direct subcortical auditory structures to respond preferentially to music.

Why we buy music

A recent study at McGill University found that the nucleus accumbens and auditory cortex interact to assign value to music through pattern recognition and prediction. This interaction involves ancient dopaminergic reward circuitry and is essential for our survival and emotional experiences.

Secrets of human speech uncovered

A team of UCSF researchers has uncovered the neurological basis of speech motor control, revealing a hierarchical and cyclical structure that exerts split-second control over articulators in fluent speech. The study has potential implications for developing computer-brain interfaces and treating speech disorders.

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'Simplified' brain lets the iCub robot learn language

Researchers developed an artificial brain system that enables robots to learn and understand new sentences containing a new grammatical structure. This technology has the potential to contribute to understanding linguistic malfunctions in Parkinson's disease and improve robots' ability to acquire language knowledge.

A neural basis for benefits of meditation

Researchers propose that mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms, enabling optimal filtering of sensory information and regulation of negative thoughts. This control is linked to the practice of mindful awareness of breath and body sensations.

Researchers map emotional intelligence in the brain

A new study of Vietnam veterans with combat-related brain injuries reveals significant overlap between general and emotional intelligence. The study found that specific brain regions, including the frontal cortex and parietal cortex, contribute to both general and emotional intelligence.

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Snap judgments during speed dating

A study published in the Journal of Neuroscience identified two brain regions involved in making rapid judgments about potential partners. The paracingulate cortex and rostromedial prefrontal cortex are active when people consider physical attractiveness and individual compatibility, respectively.

How the brain controls our habits

A new study from MIT neuroscientists has found that the brain's prefrontal cortex has a small region responsible for controlling which habits are switched on at a given time. The researchers used optogenetics to inhibit this region, allowing them to break and form new habits in rats.

The worst noises in the world: Why we recoil at unpleasant sounds

A recent study published in the Journal of Neuroscience found that the brain's amygdala and auditory cortex interact when processing negative emotions triggered by unpleasant sounds. The study used fMRI to examine how brains responded to a range of sounds, from knife-on-bottle to soothing water flowing.

Language learning makes the brain grow

A three-month intensive language study led to significant brain structure changes in language learners compared to non-language students. The hippocampus and cerebral cortex areas expanded in size, correlating with improved language skills, highlighting the cognitive benefits of language learning.

AmScope B120C-5M Compound Microscope

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Learning requires rhythmical activity of neurons

Scientists at the Max Planck Institute of Psychiatry found that effective signal transmission in the hippocampus requires theta-frequency impulses, generating waves that propagate through the brain. This discovery explains why we are more productive after drinking coffee or experiencing stress.

Math ability requires crosstalk in the brain

A new study reveals that strong communication between the left and right hemispheres of the brain predicts math performance. The research suggests a possible route to aiding individuals with dyscalculia by enhancing parietal connectivity.

Secrets of 'SuperAger' brains

Researchers identified a group of elderly people with exceptional memories and brains that resemble those of middle-aged individuals. Their cortex thickness and attention region were found to be thicker than normal aging peers, suggesting a greater number of neurons and potentially improved cognitive abilities.

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Study offers new clue on how brain processes visual information

Scientists have discovered an important clue on how the human brain filters out unimportant visual information and focuses on what's most useful. The study found that the prefrontal cortex is involved in both bottom-up and top-down attention, challenging traditional beliefs about separate areas of the brain controlling these processes.

NIH study shows the deaf brain processes touch differently

Research funded by NIH shows that deaf people use auditory cortex for touch processing and visual stimuli more than hearing people. The finding suggests that the brain adapts and takes on additional sensory tasks in response to early loss of a sense, such as hearing.

Adaptable decision making in the brain

A team of researchers has discovered that a part of the brain, known as the frontopolar cortex, plays a critical role in making short-term predictions about what will happen next. This region helps individuals make decisions in rapidly changing environments by learning from past experiences and anticipating future events.

Hands-on research

Neuroscientists at Caltech found that the primary somatosensory cortex processes both physical and emotional aspects of touch, with brain activity reflecting emotional significance even before actual contact. This finding has implications for understanding autism, sexual abuse, and physical trauma.

How human cells 'hold hands'

A team of University of Iowa researchers found that a lack of gamma-protocadherin cell adhesion molecules in the cerebral cortex disrupts neural circuitry formation. This discovery may help understand causes of human developmental disorders like autism, mental retardation, and schizophrenia.

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How selective hearing works in the brain

Scientists from UCSF used brain recordings to decode which speaker a subject was listening to, even when multiple voices were present. The study sheds light on the human brain's ability to focus on one voice in noisy environments, with implications for language learning disorders and neuroprosthetic devices.

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Neural balls and strikes: Where categories live in the brain

Neural recordings reveal brain activity that encodes visual categories in the posterior parietal cortex, outperforming the prefrontal cortex. The study suggests that the parietal cortex is more involved in the categorization process, particularly for spatial and visual tasks.

How the brain computes 3-dimensional structure

Researchers found that specific brain areas underlie perception of different 3D structures, including convex and concave surfaces. Electrical stimulation of these areas influenced monkeys' choices and decision-making times.

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Brain size may predict risk for early Alzheimer's disease

A study found that individuals with smaller brain cortex regions are more likely to develop early symptoms of Alzheimer's disease. The research identified 21% of those at high risk for cognitive decline, compared to 7% of those at average risk.

The cortex plays an essential part in emotional learning

A recent study has visualized the path of a sensory stimulus in the brain during fear learning and identified the underlying neuronal circuits. The researchers found that the cortex is essential for processing fear and anxiety, and that disinhibition of the cortical microcircuit facilitates formation of memory.

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New study to test unusual hypothesis on beta brainwaves

Jones and Moore's model suggests that neurons in the cortex experience beta oscillations when receiving a combination of two input signals at the right time and strength. The researchers aim to prove their hypothesis using optogenetics and expand their computational model to incorporate upstream brain regions.

Neurons grown from skin cells may hold clues to autism

A study using disease-in-a-dish technology has grown neurons from Timothy Syndrome patients' skin cells, revealing defects in brain wiring and cellular calcium regulation. The findings support the link between the genetic mutation and developmental abnormalities, including reduced corpus callosum size.

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A failing sense of smell can be reversed

A new animal study led by NYU Langone researchers shows that the sense of smell can be improved through training. The study found that rats trained to discriminate between similar odors could develop distinct brain activity patterns, while those not trained lost their ability to distinguish.

Sniffing out the brain's predictive power

A new study from Northwestern Medicine found that the brain uses predictive coding to generate templates of specific smells, setting up a mental expectation before sensing them. This ability provides humans with a behavioral advantage in reacting quickly and accurately to stimuli in their environment.

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Older people find it harder to see the wood for the trees

Researchers found that age-related changes in attention and Gestalt perception hinder older adults' ability to focus on global patterns. The study provides evidence of correlations between healthy aging and declines in visual perception, offering insights into cognitive domains interacting during aging.

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