Circulatory System
Articles tagged with Circulatory System
Large-scale Nordic study discovers link between polycystic ovary syndrome and heart disease
Concordia-designed CPR simulator for space use tracks the differences of blood flow in reduced gravity
A Concordia-designed simulator models hemodynamics in reduced gravity environments, revealing key differences in blood flow and pressure patterns. The system successfully reproduced effective CPR on Earth and generated consistent blood flow under both normal and hypogravity conditions.
Understanding how oxygen is delivered to tissues at the microscopic level
Researchers at Kyushu University developed a new mathematical model that simulates oxygen transport by red blood cells through tiny blood vessels and their delivery to surrounding tissues. The findings show that RBCs can naturally adjust the amount of oxygen released based on local requirements.
How brain blood vessels develop after birth
Researchers created an atlas detailing the development of brain blood vessels from birth to adulthood, revealing three distinct stages. The Lambada atlas provides a high-resolution map of vascular development, enabling researchers to explore the developing brain in 3D.
Can a new heart health metric identify fracture risk in postmenopausal women? New study finds link
A new study from Tulane University found that women with high predicted cardiovascular risk face nearly double the risk of hip fracture. The association was stronger in women under 65, and higher cardiovascular risk was linked to fractures in weakened bones in major areas.
New 4D model advances precision treatment for heart failure
A new 4D digital heart model has been shown to improve patient outcomes in cardiac resynchronization therapy (CRT) for heart failure. The model, developed at the University of Calgary, enables personalized pacemaker placement, leading to a 10.8% increase in heart function compared to standard care.
Bioengineered extracellular vesicles: A revolutionary new hope for treating cardiovascular diseases
Researchers have developed bioengineered extracellular vesicles with enhanced therapeutic functionality, which can precisely target injured cardiac tissue and deliver therapeutic cargos. These bioengineered EVs have shown promising results in preclinical models of myocardial infarction, heart failure, and pulmonary arterial hypertension.
Changes in organ donation after circulatory death in the US
Contemporary donation after circulatory death (DCD) donors are now at 44% of organ procurement organizations. DCD donations account for half of all deceased donors in the US, leading to increased reliance on these organs to maintain transplant access.
Critical crosstalk between blood vessels and immune system, showing shared pathways in major diseases
The review outlines how vascular-immune crosstalk affects various diseases, revealing novel therapeutic opportunities. It highlights the shared embryonic origin of blood vessel cells and immune cells, as well as coordinated immune cell trafficking mechanisms.
Novel framework for real-time bedside heart rate variability analysis
Scientists have developed a novel computational framework for real-time, personalized heart rate variability monitoring. The framework provides robust, adaptive alerts and improves the accuracy of HRV analysis by excluding artifact-prone periods.
AI stethoscope can help spot ‘silent epidemic’ of heart valve disease earlier than GPs, study suggests
A new study suggests that AI can help doctors detect serious heart valve disease years earlier, potentially saving thousands of lives. The AI algorithm correctly identified 98% of patients with severe aortic stenosis and 94% of those with severe mitral regurgitation.
Discovery of new lymph node architecture reshapes understanding of lymphatic physiology
A research team at Tohoku University has made a groundbreaking discovery about the anatomy of lymph nodes, revealing new structures that challenge traditional ideas about immune system function. The findings have significant implications for understanding and treating conditions like lymphedema and cancer.
Regular exercise reduces atrial fibrillation recurrence by nearly 50% after catheter ablation, study shows
A new study from CU Anschutz researchers found that regular physical activity can significantly lower post-ablation atrial fibrillation recurrence risk. Adults who engaged in moderate exercise for 30 minutes three times a week had markedly lower rates of AF recurrence compared to those who were less active.
New AI tool helps doctors treat cancer patients after heart attack
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
Chinese Neurosurgical Journal highlights eosinophils as a potential target in chordoma treatment
Researchers found that eosinophils suppress chordoma growth and induce cell death in tumor cells, suggesting them as a novel immunotherapeutic target. The study's findings provide new insight into the immune mechanisms underlying chordoma progression.
MRI scan breakthrough could spare thousands of heart patients from risky invasive tests
Researchers have developed a non-invasive method to estimate blood oxygen levels in heart failure patients using standard cardiac MRI. This breakthrough could spare thousands from undergoing risky tube procedures, allowing for safer and more frequent monitoring.
Pollution and cardiac arrest: a study by the Politecnico di Milano reveals a direct link between peak air pollution and cardiac risk
Researchers found a strong association between nitrogen dioxide levels and increased risk of cardiac arrest, with a 7% rise for every 10 micrograms per cubic metre increase. The study highlights the importance of considering environmental data in health forecasting systems.
Protein found to be key in blood vessel healing after surgical injury
Researchers have identified connexin 43 as a vital protein for endothelial repair in mice, which could lead to new therapies to improve recovery and reduce complications after vascular surgery. The study found that the protein helps blood vessels recover after damage, suggesting it could be a target for treatments.
Sons of mothers with type 1 diabetes show early signs of vascular dysfunction
A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
Chinese Medical Journal study highlights exercise-induced vascular growth as anti-aging strategy
Exercise promotes angiogenesis and lymphangiogenesis through molecular signaling pathways, enhancing vascular function and immune response. This process offers potential interventions to combat age-related decline and disease, including cardiovascular diseases, muscle atrophy, and metabolic disorders.
Predicting and lengthening pacemaker battery life
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
Flavanols in cocoa can protect blood vessel function following uninterrupted sitting - study
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
Researchers reveal pit-shaping module sustaining xylem hydraulics and rice grain yield
The study identified MYB61-PS1 as a critical regulatory module shaping the 3D structure of xylem vessel pits in rice, improving yield by sustaining vessel hydraulics and facilitating nitrogen transport. Rice plants harboring PS1 Hap2 displayed significantly improved nitrogen transport efficiency, leading to increased grain yield.
Increased aerobic fitness in paediatric athletes is linked to yet poorly understood abnormal cardiovascular changes
A new study found that pediatric athletes' cardiovascular systems adapt to increased fitness with abnormal changes, including increased cardiac mass, central blood pressure, arterial stiffness, and carotid intima-media thickness. These changes are not yet fully understood and may have long-term effects on cardiovascular health.
Some mental conditions raise heart disease risk, mortality rate by nearly 100%
A new report from Emory University reveals that certain mental health conditions can raise the risk of developing heart disease by 50-100% and adverse outcomes from existing heart conditions by 60-170%. The study emphasizes a bidirectional relationship between cardiovascular disease and mental health, highlighting the need for an integ...
Novel study reveals three new follicular lymphoma subtypes guides precision treatment
Researchers identified three distinct molecular subtypes of follicular lymphoma, offering insights into personalized treatment plans. The subtypes C1, C2, and C3 differ in their genetic profiles and tumor microenvironments, guiding the use of specific therapies.
How mutations in bodily tissues affect ageing
Two new studies from Karolinska Institutet investigate how somatic mutations in muscles and blood vessels affect ageing. The results show that such mutations can reduce muscle strength and accelerate blood vessel ageing.
How vessels in the lungs switch gears to promote healing
Researchers discovered that PAR1 triggers a structural transformation in lymphatic vessels, making them more permeable to absorb excess fluid and immune cells. This finding has implications for the treatment of lung diseases and could lead to targeted therapies.
A perfect fit: A Chinese Neurosurgical Journal study shows that Neuroform Atlas stent-assisted coiling is effective even in smaller arteries
A study published in Chinese Neurosurgical Journal found that the Neuroform Atlas stent-assisted coiling procedure is safe and effective for treating intracranial aneurysms in arteries less than 2.5 mm in diameter, with favorable outcomes and low postoperative complication rates.
Can the enzyme behind high cholesterol be turned off?
Scientists at The University of Texas at Arlington identified a new enzyme, IDO1, that plays a crucial role in inflammation and cholesterol regulation. By blocking this enzyme, macrophages regain their ability to absorb cholesterol, offering a potential new way to prevent heart disease.
Carotid plaque may pose danger over time
Researchers found that carotid artery plaques can undergo changes over time, becoming more complex and increasing the risk of internal bleeding. This study emphasizes the importance of ongoing plaque monitoring and proactive risk factor management to prevent stroke.
Intestinal bacteria influence aging of blood vessels
Researchers found that intestinal bacteria and their metabolites can accelerate blood vessel aging and trigger cardiovascular disease. The breakdown product of phenylalanine, phenylacetic acid, accumulates with age and leads to senescence of endothelial cells.
Whether it's smoking or edibles, marijuana is bad for your heart
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
Researchers identify drug candidate for difficult-to-treat heart disease
A team of researchers from the University of Arizona College of Medicine - Tucson has identified a potential drug candidate for heart failure with preserved ejection fraction (HFpEF). The study, published in Cell Metabolism, found that a key ingredient triggering HFpEF is an enzyme that converts glucose into harmful byproducts, ultimat...
NUTRITION 2025 showcases latest research on the food we eat and its impact on our health
The American Society for Nutrition's annual conference will showcase the latest research on nutrition science and its applications. NUTRITION 2025 will highlight key areas such as chronic pain, ultra-processed foods, obesity medicines, and adolescent health, featuring expert discussions and research updates.
Family Heart Foundation announces results of real-world study in 273,770 individuals with cardiovascular disease demonstrating that risk of subsequent cardiovascular event increases with rising lipoprotein(a) levels
A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.
Is your heart aging too fast?
A new MRI technique measures a person's 'functional age' of their heart, revealing how unhealthy lifestyles add years to their heart's aging process. This method has the potential to transform heart disease diagnosis and offer a lifeline to millions by catching problems early.
First-ever cardiogenic shock academy features simulation lab
The first-ever Cardiogenic Shock Academy features a simulation lab, providing hands-on training for treating patients in cardiogenic shock. More than 160 healthcare practitioners from around the world attended the academy, which aimed to address the lack of conclusive research for managing CS.
Mount Sinai Fuster Heart Hospital recognized by Press Ganey for patient experience excellence
The Mount Sinai Fuster Heart Hospital cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, a leading patient experience organization. The hospital ranks among the top 5% of healthcare providers in delivering patient experience over three years.
$6.8 million grant to expand stroke care in Hawaii
The American Heart Association will strengthen and expand Hawaii's stroke system of care, reducing death and disability rates from stroke in rural populations. The initiative aims to enhance coordination among emergency responders, hospitals, and healthcare providers.
Perioperative dynamic changes of systemic inflammatory response, gut injury, and hypoxemia in patients with acute type-A aortic dissection: an observational case-control study
Patients with acute type-A aortic dissection (ATAAD) show higher preoperative white blood cell count, IL6, IL8, TNFα, DAO, iFABP, and PGN levels, but lower PaO2/FiO2 ratio compared to controls. Postoperative levels of these markers increase, leading to worsened hypoxemia.
Dr. Christopher Kramer is new American College of Cardiology President
Dr. Christopher Kramer began a one-year term as head of the American College of Cardiology, addressing workforce issues, health equity and AI-driven solutions to improve cardiovascular care. With over 35 years of membership and leadership roles, Kramer brings experience in cardiovascular magnetic resonance imaging.
Even the mild form of COVID-19 tends to cause an imbalance in the cardiovascular system and requires attention
A study of 130 volunteers found a drastic decrease in heart rate variability after COVID-19, even in mild cases. The researchers observed an imbalance between the sympathetic and parasympathetic nervous systems, suggesting a higher risk of adverse cardiovascular outcomes.
HMRI partners with Novartis (Aust & NZ) to supercharge heart health impact
Hunter Medical Research Institute has formed a memorandum of understanding with Novartis (Aust & NZ) to explore future research projects focused on improving cardiovascular health. The partnership aims to accelerate innovation and enhance patient care through collaborative research initiatives.
A diabetes, heart failure, and kidney disease medication is the first of its kind to significantly reduce both heart attacks and strokes
A new medication approved to treat type 2 diabetes and kidney disease also significantly reduces the risk of heart attacks and strokes among these patients. Sotagliflozin, a sodium-glucose cotransporter inhibitor, blocks proteins that help control blood sugar levels and has been shown to reduce cardiovascular events by 23%.
Kennesaw State researcher receives American Heart Association grant to study heart valve disease
Sucosky's research aims to build a device replicating the bicuspid aortic valve to investigate how unusual stress leads to its hardening. The goal is to uncover molecular pathways that could be targeted with pharmaceutical treatments.
Study identifies benefits, risks linked to popular weight-loss drugs
A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.
Brachial arterial adaptations in college baseball players
Researchers found increased brachial artery diameter and blood flow in college baseball players' dominant arms, particularly pitchers. This asymmetrical adaptation may aid in injury prevention and optimize training strategies.
Electronic patient-reported outcome system implementation in outpatient cardiovascular care
The ePRO monitoring system significantly improved patient-physician communication and treatment explanations, supporting patient-centered cardiovascular care. The study found that the system's implementation enhanced patient outcomes and reduced healthcare disparities.
Chinese Medical Journal review provides insights into respiratory syncytial virus
Researchers provide comprehensive review of RSV's virology, clinical impact, and prevention strategies, emphasizing the need for effective vaccines to mitigate this critical health need. The review highlights RSV's severe impact on infants, children, and older adults, as well as its potential effects on multiple organs and systems.
Trajectory of cardiovascular health across childhood and adolescence
A cohort of 1,500 children found cardiovascular health scores began to decline at approximately age 10, associated with health behaviors. This study identifies modifiable health behaviors for prevention efforts to optimize CVH in early life and may contribute to disparities in adulthood.
The heart has its own ‘brain’
Researchers at Karolinska Institutet and Columbia University identified a mini-brain within the heart with its own nervous system that controls the heartbeat. This discovery challenges current views on how the heartbeat is controlled and may lead to new insights into heart diseases and treatments.
Mapping of atherosclerotic plaque cells may predict future risk of stroke or heart attack
A new study maps genetic traits to cellular composition of atherosclerotic plaques, predicting future stroke or heart attack risk. The research improves risk assessment and treatment for patients with atherosclerosis.
A simple risk score for weaning patients from mechanical circulatory support
Researchers at Shinshu University developed a simple risk score model to predict successful weaning from mechanical circulatory support. The scoring method uses easily measurable health indicators, such as blood pressure and cardiac output, to categorize patients into five groups with varying success rates.
Balloon angioplasty vs medical management for intracranial artery stenosis
A study published in JAMA finds that balloon angioplasty plus aggressive medical management reduces the risk of any stroke or death within 30 days. The treatment approach may be effective for symptomatic intracranial atherosclerotic stenosis, but with consideration for increased stroke risk after balloon angioplasty.
Rice bioengineers develop lotus leaf-inspired system to advance study of cancer cell clusters
Researchers create superhydrophobic array device (SHArD) mimicking the lotus leaf surface structure, enabling high-throughput generation of three-dimensional nanoscale tumor models. This platform helps study metastasis and primary tumors, shedding light on cancer progression.
Rice lab pioneers noninvasive measurement of gene expression at target locations in the brain
The Rice University lab has developed a new noninvasive technique, called REMIS, that can measure gene expression and gene therapy delivery in specific brain regions using ultrasound. This technology could revolutionize brain-based gene therapy for neurodegenerative diseases.
Method enables fast, accurate estimates of cardiovascular state to inform blood pressure management
A new mathematical method, validated with experimental animal data, provides fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes. The method accurately tracks cardiac output and systemic resistance, mirroring estimates from more invasive catheters in some cases.
Texas A&M researchers investigating the impacts of space travel on astronauts’ eye health
Researchers investigate the effects of space travel on astronauts' eye health, specifically fluid shift and its relation to Spaceflight Associated Neuro-ocular Syndrome (SANS). They examine potential countermeasures, such as lower body negative pressure, to combat microgravity-induced changes in ocular perfusion pressure.