Articles tagged with Circulatory System
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that eosinophils suppress chordoma growth and induce cell death in tumor cells, suggesting them as a novel immunotherapeutic target. The study's findings provide new insight into the immune mechanisms underlying chordoma progression.
Researchers developed an AI tool called ONCO-ACS to predict the risk of secondary heart attacks in cancer patients after a heart attack. The tool combines cancer-related factors with standard clinical data to provide reliable information for doctors to balance treatment benefits and harms.
Researchers have developed a non-invasive method to estimate blood oxygen levels in heart failure patients using standard cardiac MRI. This breakthrough could spare thousands from undergoing risky tube procedures, allowing for safer and more frequent monitoring.
Researchers found a strong association between nitrogen dioxide levels and increased risk of cardiac arrest, with a 7% rise for every 10 micrograms per cubic metre increase. The study highlights the importance of considering environmental data in health forecasting systems.
Researchers have identified connexin 43 as a vital protein for endothelial repair in mice, which could lead to new therapies to improve recovery and reduce complications after vascular surgery. The study found that the protein helps blood vessels recover after damage, suggesting it could be a target for treatments.
A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
Exercise promotes angiogenesis and lymphangiogenesis through molecular signaling pathways, enhancing vascular function and immune response. This process offers potential interventions to combat age-related decline and disease, including cardiovascular diseases, muscle atrophy, and metabolic disorders.
Researchers developed an algorithm to optimize pacemaker function usage, reducing battery power consumption and potentially extending battery life by years. By switching off unnecessary features, doctors can reduce the number of surgeries needed and lower associated costs for the NHS.
A new study from the University of Birmingham found that consuming flavanols can preserve blood vessel function in young healthy men during periods of uninterrupted sitting. The researchers tested whether high-flavanol cocoa could prevent FMD declines, and found significant protection against vascular dysfunction.
The study identified MYB61-PS1 as a critical regulatory module shaping the 3D structure of xylem vessel pits in rice, improving yield by sustaining vessel hydraulics and facilitating nitrogen transport. Rice plants harboring PS1 Hap2 displayed significantly improved nitrogen transport efficiency, leading to increased grain yield.
A new study found that pediatric athletes' cardiovascular systems adapt to increased fitness with abnormal changes, including increased cardiac mass, central blood pressure, arterial stiffness, and carotid intima-media thickness. These changes are not yet fully understood and may have long-term effects on cardiovascular health.
A new report from Emory University reveals that certain mental health conditions can raise the risk of developing heart disease by 50-100% and adverse outcomes from existing heart conditions by 60-170%. The study emphasizes a bidirectional relationship between cardiovascular disease and mental health, highlighting the need for an integ...
Researchers identified three distinct molecular subtypes of follicular lymphoma, offering insights into personalized treatment plans. The subtypes C1, C2, and C3 differ in their genetic profiles and tumor microenvironments, guiding the use of specific therapies.
Two new studies from Karolinska Institutet investigate how somatic mutations in muscles and blood vessels affect ageing. The results show that such mutations can reduce muscle strength and accelerate blood vessel ageing.
Researchers discovered that PAR1 triggers a structural transformation in lymphatic vessels, making them more permeable to absorb excess fluid and immune cells. This finding has implications for the treatment of lung diseases and could lead to targeted therapies.
A study published in Chinese Neurosurgical Journal found that the Neuroform Atlas stent-assisted coiling procedure is safe and effective for treating intracranial aneurysms in arteries less than 2.5 mm in diameter, with favorable outcomes and low postoperative complication rates.
Scientists at The University of Texas at Arlington identified a new enzyme, IDO1, that plays a crucial role in inflammation and cholesterol regulation. By blocking this enzyme, macrophages regain their ability to absorb cholesterol, offering a potential new way to prevent heart disease.
Researchers found that carotid artery plaques can undergo changes over time, becoming more complex and increasing the risk of internal bleeding. This study emphasizes the importance of ongoing plaque monitoring and proactive risk factor management to prevent stroke.
Researchers found that intestinal bacteria and their metabolites can accelerate blood vessel aging and trigger cardiovascular disease. The breakdown product of phenylalanine, phenylacetic acid, accumulates with age and leads to senescence of endothelial cells.
A new study found that chronic cannabis use, whether smoked or consumed as edibles, is associated with significant cardiovascular risks. People who regularly used marijuana had reduced blood vessel function comparable to tobacco smokers.
A team of researchers from the University of Arizona College of Medicine - Tucson has identified a potential drug candidate for heart failure with preserved ejection fraction (HFpEF). The study, published in Cell Metabolism, found that a key ingredient triggering HFpEF is an enzyme that converts glucose into harmful byproducts, ultimat...
The American Society for Nutrition's annual conference will showcase the latest research on nutrition science and its applications. NUTRITION 2025 will highlight key areas such as chronic pain, ultra-processed foods, obesity medicines, and adolescent health, featuring expert discussions and research updates.
A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.
A new MRI technique measures a person's 'functional age' of their heart, revealing how unhealthy lifestyles add years to their heart's aging process. This method has the potential to transform heart disease diagnosis and offer a lifeline to millions by catching problems early.
The first-ever Cardiogenic Shock Academy features a simulation lab, providing hands-on training for treating patients in cardiogenic shock. More than 160 healthcare practitioners from around the world attended the academy, which aimed to address the lack of conclusive research for managing CS.
The Mount Sinai Fuster Heart Hospital cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, a leading patient experience organization. The hospital ranks among the top 5% of healthcare providers in delivering patient experience over three years.
The American Heart Association will strengthen and expand Hawaii's stroke system of care, reducing death and disability rates from stroke in rural populations. The initiative aims to enhance coordination among emergency responders, hospitals, and healthcare providers.
Patients with acute type-A aortic dissection (ATAAD) show higher preoperative white blood cell count, IL6, IL8, TNFα, DAO, iFABP, and PGN levels, but lower PaO2/FiO2 ratio compared to controls. Postoperative levels of these markers increase, leading to worsened hypoxemia.
Dr. Christopher Kramer began a one-year term as head of the American College of Cardiology, addressing workforce issues, health equity and AI-driven solutions to improve cardiovascular care. With over 35 years of membership and leadership roles, Kramer brings experience in cardiovascular magnetic resonance imaging.
A study of 130 volunteers found a drastic decrease in heart rate variability after COVID-19, even in mild cases. The researchers observed an imbalance between the sympathetic and parasympathetic nervous systems, suggesting a higher risk of adverse cardiovascular outcomes.
Hunter Medical Research Institute has formed a memorandum of understanding with Novartis (Aust & NZ) to explore future research projects focused on improving cardiovascular health. The partnership aims to accelerate innovation and enhance patient care through collaborative research initiatives.
A new medication approved to treat type 2 diabetes and kidney disease also significantly reduces the risk of heart attacks and strokes among these patients. Sotagliflozin, a sodium-glucose cotransporter inhibitor, blocks proteins that help control blood sugar levels and has been shown to reduce cardiovascular events by 23%.
Sucosky's research aims to build a device replicating the bicuspid aortic valve to investigate how unusual stress leads to its hardening. The goal is to uncover molecular pathways that could be targeted with pharmaceutical treatments.
A recent study published in Nature Medicine analyzed over 2 million veterans taking GLP-1RA medications, finding benefits to cognitive and behavioral health while revealing increased risks for pancreatitis and kidney conditions. The study also showed decreased risks of seizures, addiction, suicidal ideation, and neurocognitive disorders.
Researchers found increased brachial artery diameter and blood flow in college baseball players' dominant arms, particularly pitchers. This asymmetrical adaptation may aid in injury prevention and optimize training strategies.
The ePRO monitoring system significantly improved patient-physician communication and treatment explanations, supporting patient-centered cardiovascular care. The study found that the system's implementation enhanced patient outcomes and reduced healthcare disparities.
Researchers provide comprehensive review of RSV's virology, clinical impact, and prevention strategies, emphasizing the need for effective vaccines to mitigate this critical health need. The review highlights RSV's severe impact on infants, children, and older adults, as well as its potential effects on multiple organs and systems.
A cohort of 1,500 children found cardiovascular health scores began to decline at approximately age 10, associated with health behaviors. This study identifies modifiable health behaviors for prevention efforts to optimize CVH in early life and may contribute to disparities in adulthood.
Researchers at Karolinska Institutet and Columbia University identified a mini-brain within the heart with its own nervous system that controls the heartbeat. This discovery challenges current views on how the heartbeat is controlled and may lead to new insights into heart diseases and treatments.
A new study maps genetic traits to cellular composition of atherosclerotic plaques, predicting future stroke or heart attack risk. The research improves risk assessment and treatment for patients with atherosclerosis.
Researchers at Shinshu University developed a simple risk score model to predict successful weaning from mechanical circulatory support. The scoring method uses easily measurable health indicators, such as blood pressure and cardiac output, to categorize patients into five groups with varying success rates.
A study published in JAMA finds that balloon angioplasty plus aggressive medical management reduces the risk of any stroke or death within 30 days. The treatment approach may be effective for symptomatic intracranial atherosclerotic stenosis, but with consideration for increased stroke risk after balloon angioplasty.
Researchers create superhydrophobic array device (SHArD) mimicking the lotus leaf surface structure, enabling high-throughput generation of three-dimensional nanoscale tumor models. This platform helps study metastasis and primary tumors, shedding light on cancer progression.
The Rice University lab has developed a new noninvasive technique, called REMIS, that can measure gene expression and gene therapy delivery in specific brain regions using ultrasound. This technology could revolutionize brain-based gene therapy for neurodegenerative diseases.
A new mathematical method, validated with experimental animal data, provides fast, reliable, and minimally invasive way of determining how to treat critical blood pressure changes. The method accurately tracks cardiac output and systemic resistance, mirroring estimates from more invasive catheters in some cases.
Researchers investigate the effects of space travel on astronauts' eye health, specifically fluid shift and its relation to Spaceflight Associated Neuro-ocular Syndrome (SANS). They examine potential countermeasures, such as lower body negative pressure, to combat microgravity-induced changes in ocular perfusion pressure.
A breath-holding test assesses cardiorespiratory health and predicts postoperative pain risk in laparoscopic gynecological surgery. The study analyzed 489 patients and found significant correlation between breath-holding time and pain scores.
A new study from the University of Copenhagen found that long-term exposure to air pollution accelerates cognitive decline and increases risk of dementia. The research, which followed a cohort of nurses for 27 years, also suggests that physical activity may mitigate the adverse effects of air pollution.
Researchers investigated the effects of hypoxia on hemodynamic and metabolic parameters in patients with Fontan circulation. The study found that oxygen saturation levels remain stable during sleep and that prolonged high-altitude exposure is well-tolerated, offering new perspectives for patients with Fontan circulation.
A new study suggests that stimulating specific areas of the brain can affect heart rate in individuals with depressive disorders. The researchers found high accuracy in identifying optimal treatment spots using heart rate measurements during brain stimulation.
A new study from Israel found that nearly 1 in 5 adults with congenital heart disease developed an abnormal heart rhythm during a five-year study. Those who developed arrhythmias had twice the risk of early death and increased hospitalization rates compared to those without irregular heart rhythms.
Researchers aim to address LVAD shortcomings, reducing blood damage and clotting risk through innovative designs and coatings. A novel flexible stented blood inlet and slippery hydrophilic coatings will be used to prevent flow stasis and clot formation.
Researchers are developing minimally invasive techniques to repair and regenerate tissue in aortic aneurysms using actively targeted, drug-releasing nanoparticles. The team found that rod-shaped particles with high aspect ratios were selectively taken up by diseased endothelial cells, leading to improved therapy outcomes.
A Phase 2B clinical trial, led by City of Hope, found that carvedilol may improve heart health markers and reduce the risk of heart failure in childhood cancer survivors. The study suggests that carvedilol could benefit long-term survivors and those who are highly adherent to the treatment.
Eating fatty foods during stressful periods can reduce brain oxygenation and cause poorer vascular function in adults. Consuming low-fat food and drinks may help mitigate this effect.
The American Heart Association and Neurocritical Care Society emphasize the need for improved critical care management of patients after cardiac arrest. The consensus statement highlights gaps in knowledge, particularly in areas like neurological, cardiac, and gastrointestinal care.
A literature review found that prioritizing circulation before the airway in trauma patients with major blood loss leads to improved outcomes, including lower mortality rates. This approach, known as CAB, has gained acceptance over the ABC model and is now being recommended by the American College of Surgeons.
Researchers are conducting a four-year study to investigate the effectiveness of acupuncture in reducing stable angina-related chest pain. The study will enroll 112 participants and compare acupuncture treatment to watching TED Talk videos for symptom relief.
A new study reveals that women with atrial fibrillation (AF) have comparable outcomes to men when undergoing pulsed field ablation (PFA), a safer and more precise procedure. The results show improved AF recurrence rates in women after PFA, making them an eligible candidate for this life-enhancing treatment.
A study in fruit flies reveals a potential connection between a respiratory system defect and the development of aortic aneurysms in humans. Researchers identified proteins that play a crucial role in maintaining tube structure and integrity, which may also be relevant to human tubular diseases.