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How the brain turns our intended words into the sounds of speech

A new study from UC San Francisco challenges the traditional view of how the brain strings sounds together to form words and orchestrates the movements to pronounce them. The brain relies on a wider network of neurons across many brain areas, centered in the middle precentral gyrus, to coordinate speech-motor sequencing.

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Are groovy brains more efficient?

A new study from UC Berkeley reveals that the depth of small grooves on the brain's surface is correlated with increased connectivity between regions involved in reasoning. The researchers found that these tertiary sulci, unique to humans, may help explain individual differences in cognitive performance and serve as diagnostic indicato...

Focused ultrasound halts growth of debilitating brain lesions

A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.

Brain areas necessary for reasoning identified

A team of researchers at UCL has identified key brain regions essential for logical thinking and problem-solving. They used lesion-deficit mapping to study patients with brain lesions caused by stroke or tumors and found that damage to the right frontal lobe impaired reasoning skills.

Study maps new brain regions behind intended speech

Researchers identified specific non-frontal brain areas involved in speech intent, which can be used to distinguish between language production and perception. This study is a crucial step towards developing a brain-computer interface to treat patients with Broca's aphasia.

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New gene therapy could significantly reduce seizures in severe childhood epilepsy

Researchers at UCL Queen Square Institute of Neurology have developed a new gene therapy that significantly reduces seizures in mice with focal cortical dysplasia. The treatment, which involves the overexpression of a potassium channel, has shown an average reduction of 87% in seizures without affecting the mouse's memory or behavior.

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Connections in the brain involved in epileptic seizures identified

A study published in Brain found that disconnecting nerve pathways in the brain can lead to improved seizure freedom in patients with frontal lobe epilepsy. The research, involving 47 patients, revealed that cutting these connections resulted in 88% of patients being seizure-free after three years.

Brain area necessary for fluid intelligence identified

A new study has mapped the parts of the brain that support fluid intelligence, a key feature of human cognition. The research found that patients with damage to the right frontal regions performed poorly in tasks requiring problem-solving and reasoning.

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Speech as a new diagnostic tool in ALS and FTD

A new study aims to diagnose severe neurodegenerative diseases like ALS and FTD with the help of speech tests. AI can analyze subtle nuances of speech patterns, including pauses, speed, and melodic aspects, to detect early changes.

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New study reveals how the brain says ‘oops!’

Researchers at Cedars-Sinai discovered how the brain uses a group of neurons in the frontal lobe to monitor performance, enabling humans to learn from mistakes and develop specific skills. This mechanism allows for flexibility in learning new tasks and adjusting focus based on conflict or difficulty encountered.

How the brain processes sign language

Researchers identified Broca's area as a key region for sign language processing, showing an overlap with areas used for spoken language. The study highlights the brain's linguistic specialization and its role in processing abstract information across different forms of language.

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What EEGs tell us about COVID-19 and the brain

Research identifies commonalities in COVID-19 patients' brain activity, highlighting potential long-term effects on older males. Abnormal EEG readings suggest permanent brain damage, prompting the need for comprehensive care including brain imaging.

How the brain helps us navigate social differences

Researchers found that brain activity increased in the left dorsolateral prefrontal cortex when participants conversed with someone of a different socioeconomic background. This increase in activity suggests that our brains have developed a system to help us deal with diversity, supporting previous research on frontal lobe systems and ...

CalDigit TS4 Thunderbolt 4 Dock

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Why the language-ready brain is so complex

Neuroscientist Hagoort challenges the classical view that language is confined to two major areas in the left half of the brain, instead proposing a multi-brain-network view that incorporates multiple regions and operations, including those shared with other cognitive domains like music and arithmetic.

Marmoset study gives insights into loss of pleasure in depression

A recent study using marmosets identified the brain region responsible for anhedonia, a key symptom of depression. The researchers found that over-activity in this region blunts excitement and motivation, but a commonly used antidepressant ketamine blocks these effects, suggesting new treatment possibilities.

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Where hominid brains are concerned, size doesn't matter

Researchers found that Homo naledi's brain had a human-like shape and structure, similar to humans, but smaller in size. The study suggests that the species' behavior may have reflected the shape of its brain more than its size, raising new questions about human evolution and the evolution of brain size.

Where language pionieer Paul Broca and alien music meet

Researchers found that the right hemisphere equivalent of Broca's area processes musical non-local dependencies, and that this processing is integrated with working memory to determine grammatical rules. The study uses a novel 'genre' of music to tease apart contributions of local and non-local dependencies.

Offbeat brainwaves during sleep make older adults forget

Research at UC Berkeley found that older adults' slow brainwaves during deep sleep fail to synchronize with speedy electrical bursts, preventing them from effectively consolidating new memories. The aging brain's failure to coordinate these two brain waves is likely due to degradation or atrophy of the medial frontal cortex.

Voices and emotions: The forehead is the key

Researchers at the University of Geneva discovered the brain regions used to categorize emotions communicated vocally, highlighting the crucial role of the frontal lobe. The study found that the inferior frontal cortex is activated when categorizing and discriminating emotions from voices.

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Wired for sound: Enraging noises caused by brain connection overdrive

Researchers at Newcastle University have discovered abnormal changes in the brain's frontal lobe and emotional control mechanism in individuals with misophonia. The study found that trigger sounds evoked increased heart rate and sweating, and that patients had strikingly similar clinical features despite being undiagnosed by current me...

Scientists track restoration of communication in minimally conscious patient

A severely brain-injured woman regained the ability to communicate through eye movements, with researchers capturing the restoration process by measuring brain structure and function. The study suggests that other patients in chronic care facilities may harbor organized brain function, raising questions about diagnosis and treatment.

During infancy, neurons are still finding their places

Researchers discovered a population of previously unrecognized young neurons that migrate in the human brain during the first few months of life. These neurons contribute to inhibitory circuits, balancing excitatory activity, and are associated with the plasticity of the brain observed during postnatal development.

People with alcohol dependency lack important enzyme

A study published in Molecular Psychiatry identified an enzyme whose production is turned off in nerve cells of the frontal lobe when alcohol dependence develops. This deficiency leads to continued use of alcohol despite adverse consequences. The research team hopes to develop effective medicines for treating alcoholism and contributin...

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When punishment doesn't fit the crime

Research reveals that people with traumatic brain injuries (TBI) have difficulty judging the severity of crimes and assigning appropriate punishments. This impairment can affect their social skills, such as empathy and rational judgments, leading to poorer prognoses for resuming normal work and family life.

Brain's iconic seat of speech goes silent when we actually talk

A new study reveals that Broca's area, traditionally considered the command center for human speech, actually switches off when we speak out loud. This finding has major implications for diagnosing and treating stroke, epilepsy, and brain injuries that result in language impairments.

Study links poor sleep quality to reduced brain gray matter in Gulf War vets

A new study found an association between poor sleep quality and reduced gray matter volume in the brain's frontal lobe of Gulf War veterans. The study controlled for comorbid psychiatric conditions and found that poorer subjective sleep quality was associated with reduced total cortical and regional frontal lobe gray matter volumes.

Brain frontal lobes not sole centre of human intelligence

Research from Durham University suggests that brain frontal lobes are not disproportionately enlarged relative to other areas in humans and other species. The study found that supposedly 'primitive' areas like the cerebellum played an equally important role in expanding the human brain.

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Brazilian mediums shed light on brain activity during a trance state

A study published in PLOS ONE reveals that experienced Brazilian mediums show lower brain activity in certain areas during psychography, a form of writing believed to be guided by spirits. The findings suggest an absence of focus, self-awareness, and consciousness during the trance-like state.

Thinking and choosing in the brain

A study published in PNAS found that different regions of the frontal lobes are responsible for behavioral control and decision making. The researchers mapped brain lesions in over 300 patients and showed that damage to specific areas can impair reasoning and decision-making abilities.

Adaptable decision making in the brain

A team of researchers has discovered that a part of the brain, known as the frontopolar cortex, plays a critical role in making short-term predictions about what will happen next. This region helps individuals make decisions in rapidly changing environments by learning from past experiences and anticipating future events.

Creativity and human reasoning during decision-making

Researchers found that humans can only monitor up to three strategies while making decisions, and creativity is favored over reliable options. The frontal lobe plays a crucial role in this process, with individual differences in performance linked to variations in creative ability.

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'Explorers,' who embrace the uncertainty of choices, use specific part of cortex

A study published in the journal Neuron reveals that individuals with strategic decision-making skills, known as 'explorers,' use a specific region of the prefrontal cortex to calculate relative uncertainty. This brain area is not active in non-explorers, suggesting a specialized cognitive process for making uncertain decisions.

What you want vs. how you get it

A neuroeconomics study from McGill University shows that the brain employs two separate regions and processes in valuing 'stimuli' (goods) versus 'actions'. The findings, published in the Journal of Neuroscience, provide new insights into frontal lobe damage and its effects on decision making.

Brain imaging reveals why we remain optimistic in the face of reality

Research shows that optimistic individuals tend to filter out negative information, updating their estimates only when the new data is better than expected. This faulty frontal lobe function can lead to unrealistic predictions and a lack of caution, with potential downsides for mental health and decision-making.

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An underlying cause for psychopathic behavior?

A new study suggests that an underlying cause of psychopathic behavior may be frontal lobe dysfunction, with participants showing striking similarities to those with brain damage. The research examined the emotional and cognitive aspects of Theory of Mind abilities in criminal offenders and patients with frontal lobe damage.