A study in mice suggests that a spectral imaging system could provide immediate results during Hirschsprung's disease surgeries, increasing patient safety and operating room efficiency. This technology identifies diseased tissue based on wavelength, allowing precise localization of interventions.
A research team at UCSC and Salk Institute has discovered a new retinal cell type called the upsilon cell, which shares similar properties with Y retinal ganglion cells. The discovery may help humans see motion and is a significant step towards understanding how primates process visual information.
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The human retina can transmit data at roughly 10 million bits per second, similar to Ethernet connections. Researchers used a miniature multi-electrode array to record electrical impulses from guinea pig retinas, revealing that sluggish cells convey most of the information.
Researchers discovered that light-sensing retinal ganglion cells are active and functioning at birth, surprising the developmental timeline of the mouse retina. The cells react to light in two ways, sending messages to parts of the brain controlling circadian rhythms and visual development.
Researchers have developed a biologically accurate computer simulation of synaptic function, indicating that the synapse may behave like a shotgun firing buckshot-like bursts of neurotransmitter to reach receptors arrayed beyond known receiving sites. The new data suggest an alternative mode of neurotransmission called ectopic release.
Researchers find adenosine controls timing of neural activity in developing visual system, shedding light on disorders like fetal anti-convulsant syndrome. The discovery could lead to new therapeutic approaches, such as recreating spontaneous waves of activity for adult retinas.
A researcher is studying how diabetes affects ganglion cells and developing a potential treatment using sigma receptor ligands. The goal is to prevent ganglion cell death and the growth of new blood vessels that obstruct vision.
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Researchers identify a crucial pathway in the retina that allows the pupil to respond to light, even when rods and cones are absent. This discovery suggests a complex non-visual photoreceptive system in the inner retina that helps regulate the body's internal clock and unconscious activities.
The study reveals a sophisticated neural computation in the retina that enables directional motion detection. The circuit, involving three redundant mechanisms, is crucial for tracking moving objects and providing dynamic visual information to the brain.
Researchers mapped the neural circuitry of a light-sensing system that governs the body's internal clock and regulates sleep-wake cycles, discoveries that could lead to new treatments for jet lag and depression. The study identified melanopsin as a key player in this system.
Researchers at Washington University School of Medicine have identified a potential new approach to treating glaucoma by inhibiting an enzyme that produces excessive nitric oxide, leading to cell damage. The study found that rats with elevated eye pressure lost less than 10% of their retinal ganglion cells when treated with the inhibitor.