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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Brainless memory makes the spinal cord smarter than previously thought

Researchers at RIKEN Center for Brain Science discovered neural circuitry in the spinal cord that enables brain-independent motor learning and recall. The study found two critical groups of neurons: one necessary for new adaptive learning and another for recalling adaptations once learned.

In the evolution of walking, the hip bone connected to the rib bones

A new reconstruction of the 375-million-year-old fossil fish Tiktaalik reveals that its ribs likely attached to its pelvis, enabling support of the body and potentially leading to the evolution of walking. This discovery provides insights into the major evolutionary transition from fish to four-limbed vertebrates.

Probably not for sex

Scientists at the Smithsonian Tropical Research Institute found that matador bugs wave their legs to signal aggression or to advertise their toxicity to predators, not for sexual attraction. The study revealed no differences in waving behavior between males and females.

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Baboons ‘crouch and sprint’ to take standing up in their stride

Researchers discovered that baboons employ an efficient strategy to transition from quadrupedal to bipedal walking by 'crouching' their hindlimbs and 'sprinting' them forward under their torso. This process enables the animals to maintain a natural gait while standing upright, requiring minimal energy expenditure.

A speedy trial: What it takes to be the fastest land predator

The study reveals that cheetahs use two types of flight during galloping, which enables them to accelerate to high speeds. The team's simple model and measurements with real-world data confirm the findings, suggesting a key factor in cheetahs' exceptional speed.

Drop your weapons!

A study by Ummat Somjee and colleagues found that male leaf-footed bugs invest more in their large hind legs than females do, which are used as weapons in male-male duels. The team measured energy use of live bugs with and without hind legs to calculate the hidden energetic cost of maintaining these structures.

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URI scientist: Long-legged lizards better adapted for hurricane survival

A University of Rhode Island professor has discovered that lizards with shorter hind legs are more likely to survive hurricanes due to their ability to cling to vegetation. This unexpected finding suggests that natural selection may be at play, favoring traits that enhance survival during extreme weather events.

Leggy lizards don't survive the storm

Researchers found that survivors had larger toe pads on forelimbs and hindlimbs compared to pre-storm populations. Survivors also had proportionately longer fore legs and shorter back legs with smaller bodies. These findings suggest natural selection favors certain characteristics in response to extreme weather events.

Humans risked limb ischemia in exchange for bipedal walking

Researchers compared mouse and human blood vessels using three-dimensional imaging, revealing that mice have a more robust vascular structure against lower limb ischemia. The inferior gluteal artery in mice extends further than in humans, allowing for better bypassing of obstructions.

Paleontologists solve pterosaur pelvis puzzle

Researchers have identified a rare pterosaur pelvis in Alberta's Dinosaur Provincial Park, showing that these ancient reptiles were well adapted for walking on land. The study provides evidence that azhdarchids likely used their powerful hindlimbs to transport themselves on the ground.

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Baleen whales' ancestors were toothy suction feeders

Researchers have discovered a 36.4-million-year-old whale fossil that suggests baleen whales' ancestors were toothy suction feeders, diverging from their hunting lifestyle to filter-feed tiny marine animals. The study also reveals that whales likely lost hind limbs more recently than previously estimated.

Pigeon foot feather genes identified

Researchers discovered two genes, Pitx1 and Tbx5, responsible for developing feathered feet in pigeons. The study suggests that these genes may have played a role in the evolution of feathers in dinosaurs and early birds. The findings provide insight into how skin regions can be controlled to produce scales or feathers.

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Spaceflight may increase susceptibility to inflammatory bowel disease

A new study suggests that spaceflight can disrupt intestinal homeostasis and increase colitis susceptibility in mice. The research found altered composition of intestinal bacteria, decreased regulatory T cells, and increased neutrophils in the colon tissues of hindlimb-suspended mice.

Ancient snakes -- a new hiss-tory

Researchers from Yale University have reconstructed the ancestral snake's body plan, revealing a nocturnal, stealth-hunting predator with complete ankles and toes. The study sheds light on the origin of snakes, which originated around 128.5 million years ago during the Early Cretaceous period.

Extinct giant kangaroos may have been hop-less

New research suggests that extinct giant kangaroos likely walked instead of hopped, with stiff backs and strong joints supporting their body posture. The study analyzed anatomical differences in limb bones compared to other kangaroo species.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

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Single gene separates queen from workers

Researchers have identified a single gene, Ultrabithorax (Ubx), that determines the distinct leg features of worker honey bees, enabling them to collect and transport pollen. The gene plays a critical role in the evolution of social behavior among honey bees, separating queens from workers.

Castaway lizards offer new look at evolutionary processes

A study by Jason Kolbe and colleagues reveals that the 'founder effect' persists even as lizard populations adapt to new environments. The research found that differences caused by the founder effect are retained in lizards with varying limb lengths, suggesting a complex interaction between natural selection and genetic variation.

A small step for lungfish, a big step for the evolution of walking

African lungfish demonstrates unique walking behavior using its thin pelvic limbs, propelling itself forward and lifting its body off the bottom surface. This discovery suggests that many developments necessary for the transition from water to land could have occurred in lobe-finned ancestors of the lungfish long before early tetrapods.

Marsupial embryo jumps ahead in development

Researchers found that marsupial embryos develop forelimbs earlier than expected, using a unique genetic program. This breakthrough suggests that developmental processes may be more flexible than previously thought, allowing for adaptability in marsupials.

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Final moments of bee landing tactics revealed

Researchers discovered bees use their antennae to estimate surface slope, allowing them to orient correctly and land on surfaces ranging from horizontal to ceilings. By slowing down in the final moments before touchdown, bees control their approach and optimize landing speed.

Embryology study offers clues to birth defects

A new embryology study clarifies the role of retinoic acid in limb development and finds that it controls forelimb budding but not hindlimb patterning. The research may lead to new therapeutic measures for congenital limb defects such as Holt-Oram syndrome.

Grouping muscles to make controlling limbs easier

A team of researchers at Northwestern University discovered a new approach to control movement in limbs by grouping muscles, which could simplify the restoration of muscle movements in people with paralysis. By reducing the number of variables, this method can achieve similar results as controlling individual muscles.

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Lizards pull a wheelie

A team of scientists found that lizards running on two legs is due to their acceleration, which creates a turning force acting on the lizard's torso, lifting it off the ground. The researchers suggest that 'pulling a wheelie' is the most likely explanation for the lizards' bipedalism.

Tracking feline memories on the move

A new study reveals that cats can remember having stepped over an obstacle for at least ten minutes, but only if their forelegs have done so. In contrast, visual memories of the obstacle proved fleeting. This finding suggests that cats' working memories may be longer than previously thought.

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How ancient whales lost their legs, got sleek and conquered the oceans

Scientists used fossil and developmental data to pinpoint the genetic changes that led to whales losing their hind limbs. The gradual shrinkage of hind limbs was caused by slowly accumulated genetic changes, while the actual loss occurred when a drastic change inactivated the Sonic hedgehog gene.

MicroRNA may have fail-safe role in limb development

Researchers have identified a specific microRNA - miR 196 - playing a protective role in hindlimb development, but not forelimb development, suggesting a fail-safe mechanism to regulate gene expression. This finding may be useful in understanding birth defects and has implications for the regulation of protein expression in limbs.

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