Research on the structure and workings of the human brain. Covers prenatal brain development, structural changes in disease, gray and white matter, and brain stimulation.
Researchers developed an AI model to analyze noncoding DNA mutations' impact on brain function and development, identifying potential causes of complex brain disorders like autism. The study sheds light on the origins of brain disorders and may lead to novel treatments.
Researchers use movie clips to study mouse brain activity, revealing novel ways to diagnose learning and memory disorders. The discovery points to new ways to tackle Alzheimer's and improve artificial intelligence.
Researchers have discovered that cocaine addiction is associated with faster brain aging, with changes in DNA methylation in the prefrontal cortex contributing to this effect. The study, which analyzed cryo-preserved brains of deceased male donors, found that cells in this region appeared biologically older in individuals with CUD.
A study by Ohio State University found that children as young as 4 years old utilize a brain network, known as the multiple demand network, to tackle difficult cognitive problems. This network enables focus, memory management, and problem-solving skills, similar to those seen in adults.
Researchers employed computer vision to extract social behaviors and linked them to brain synchronization patterns in a novel approach. During cooperative play, brain synchronization was strongest when participants shared gaze, while individual play showed increased within-brain synchronization.
Researchers have discovered a way to construct and control oxygen-deprived walls in nanoscopically thin materials, which can store data in multiple electronic dialects. These walls can retain their data states even when devices turn off, paving the way for next-gen electronics with enhanced memory capabilities.
Researchers found no significant evidence of harm in lowering blood pressure targets after endovascular treatment, but trends suggested marginal benefit and potential worsening of long-term disability. Clinicians should consider auto-regulation of blood pressure unless above 180 mm Hg.
A new neuroprotectant medication called ApTOLL has been shown to improve survival and reduce long-term disability among patients with stroke. The study found that ApTOLL, when used in conjunction with standard treatments, reduced death and brain damage, suggesting a promising new approach to treating stroke.
A recent study found that about 1 in 5 people who survived an ischemic stroke had irregular heart rhythms, atrial fibrillation, due to atherosclerosis. The study suggests that these patients are at increased risk of recurrent strokes and highlights the need for continuous cardiac monitoring to detect unsuspected atrial fibrillation.
Research found that cocaine use disorder causes significant gene expression changes in brain regions associated with reward and habit formation, contributing to persistent behavioral abnormalities. The study also identified overlapping molecular changes between cocaine and opioid use disorders, offering potential for targeted treatments.
A large international clinical study found that patients with large strokes had significantly better recovery after endovascular thrombectomy plus medical management. The SELECT2 study showed almost 20% of patients who received thrombectomy regained functional independence, compared to 7% on medical treatment only.
A new study found that children in a modern forager society developed specialized foraging skills from an early age, which may have enabled the human species to afford larger brains. The research also showed gender-specific differences in foraging skills, with girls collecting tubers and boys climbing trees to collect fruits.
Researchers propose using brain scans to measure similarity in trademark cases, reducing inconsistencies and bias. This approach provides a reliable method for determining similarity without relying on subjective surveys or expert opinions.
A new study found that children with conduct disorder who experienced childhood maltreatment have more extensive brain structural changes compared to those without maltreatment. The study highlights the unique contribution of childhood maltreatment to these changes and provides neurobiological insights into the heterogeneity of CD.
The work group reframed what is clinically meaningful to slow Alzheimer's disease progression, including the need for combination therapies and realistic expectations of benefits and risks. Slowing brain deterioration by four to six months in early stages may preserve function, leading to meaningful outcomes for patients and families.
The Human Brain Project Summit 2023 will highlight the scientific achievements of the project at the interface of neuroscience and technology. Researchers will present cutting-edge research on European advances in neuroscience and applications in medicine and brain-derived technologies.
Researchers found that children perceive time differently than adults, with a shift in bias around age 7. Children tend to overestimate the duration of an eventful video and underestimate that of an uneventful one, while adults exhibit the opposite bias. This switch is unexpected based on biological models of time perception.
A new smartphone application called FAST.AI uses machine learning algorithms to recognize facial asymmetry, arm weakness, and speech changes in people experiencing a stroke. The app's accuracy was validated through a study involving nearly 270 patients with acute stroke, showing promise as a tool for prompt individuals to seek care.
Researchers found that patients treated with butylphthalide experienced milder neurological symptoms and better functioning at three months after a stroke compared to those who received a placebo. The study suggests potential benefits of this celery seed-derived medication in treating ischemic strokes.
A new study found that Black and Hispanic stroke survivors in the US are less likely to receive treatment for common complications, despite improved overall stroke survival rates. Researchers analyzed electronic health records from 2002 to 2022 and matched patients based on 41 factors to minimize biases.
Research suggests that poor oral health may contribute to declines in brain function and cognitive abilities. A recent study analyzed the relationship between oral health and brain health among approximately 40,000 adults and found a potential link between gum disease and white matter hyperintensities.
Research highlights underuse of dual blood thinners in women after minor stroke or transient ischemic attack (TIA), with potential benefits for stroke prevention. A study analyzed electronic health records of 2,953 adults and found that women were less likely to receive the treatment regimen, despite evidence suggesting its effectiveness.
A new study finds that Mexican American stroke survivors are less likely to receive intensive rehabilitation services compared to non-Hispanic white peers. Nearly one-third of all stroke survivors in the study did not receive any rehabilitation within 90 days of their stroke.
A new study suggests that intensive blood pressure treatment may slow the accumulation of toxins in the brain's perivascular spaces, a dynamic area involved in brain clearance. This finding is significant for understanding the relationship between high blood pressure and cognitive decline.
Researchers discovered that bone marrow transplants can halt the development and progression of brain blood vessel disease in adults with sickle cell disease. The study found that receiving stem cell transplants led to positive changes in blood vessels, reducing the risk of stroke among patients with the condition.
Researchers found that Black children experienced more childhood adversity than White children, leading to differential changes in brain regions linked to psychiatric disease. The study suggests that structural racism may play a significant role in these differences.
A 20-year study reveals that recent advances in surgical and clinical care have significantly reduced brain injuries in babies with congenital heart disease. Infants who received higher postoperative blood pressure had a 20% lower risk of brain injury compared to those in earlier stages.
A new optogenetic tool, OPN4-mGluR1, allows researchers to modulate mGluR1 signalling in the cerebellum using light. This enables the study of synaptic plasticity and its role in motor learning, offering new possibilities for understanding cerebellar-associated diseases.
A Tufts-led team discovered a brain region marker that indicates vulnerability to developing post-traumatic stress disorder (PTSD). The study found heightened amygdala activation in response to neutral facial expressions, suggesting an acquired characteristic of PTSD. This finding may inform early intervention strategies for individual...
A recent study published in Science Advances found that individuals with similar ideologies have more similar neural fingerprints of political words and process new information in a polarized way. The researchers used a range of methods, including fMRI and representation similarity analysis, to explore how the brains of people who iden...
Researchers found that calibrating rates of information delivery to match individual brainwave cycles speeds up cognitive skill improvement. This technique, called entrainment, increases capacity to absorb and adapt new information.
Research suggests that a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant strains. The FDA-approved BPaL regimen is not effective in treating TB meningitis because bedaquiline and linezolid cannot penetrate the blood-brain barrier.
Researchers created monthly infant brain atlases to track normative trends in brain development. The atlases reveal changes in brain structure, cortical geometry, and tissue contrast, shedding light on conditions like ADHD and dyslexia. The study aims to facilitate discovery of new insights into child cognition and social behavior.
Researchers developed a blood-based test that predicts Alzheimer's disease risk by analyzing changes in brain cell growth and division. The study found that the body's circulatory system can modulate the formation of new brain cells, and that this process occurs 3.5 years before a clinical diagnosis.
A personalized brain modeling approach is being tested in a large-scale clinical trial for drug-resistant epilepsy, aiming to improve surgery preparation and patient specificity. The technique uses virtual models of patients' brains to simulate abnormal activity during seizures, helping clinicians identify target areas more effectively.
A high fat diet can disrupt the brain's ability to regulate calorie intake by affecting astrocytes, which control signaling pathways between the brain and gut. This can lead to overeating and weight gain. Understanding this mechanism could help develop therapies to treat obesity.
Early cardiovascular disease has been linked to poorer cognitive performance, accelerated cognitive decline, and poor brain health in middle age. Researchers found that participants with early cardiovascular disease performed worse on cognitive tests and had more white matter hyperintensities and decreased brain tissue integrity.
Researchers found abnormal 12-hour gene activity cycles in postmortem brains of patients with schizophrenia. The study identified altered timings of neural connections and mitochondrial function, suggesting potential underlying causes for behavioral abnormalities.
A new study by University of British Columbia researchers found that brief exposure to diesel exhaust causes decreased brain connectivity and may impair cognitive performance. The study's findings suggest a link between air pollution and altered brain network connectivity in humans.
Research published in the Journal of Epidemiology & Community Health found that daily moderate and vigorous physical activity is positively associated with mid-life brain power. However, replacing these activities with just 6-7 minutes of sedentary behavior negatively impacts cognitive performance. The study analyzed data from over 4,4...
A study found that people can recall the location of over 100 objects on a grid with high accuracy, even after removing all images. Additionally, participants localized 60-80% of old items to within +/-10% of their correct time.
Researchers identified structural changes in the thalamus and strengthened connections with the temporal cortex, enabling visual cortex activation through non-visual stimuli.
Researchers have developed a machine learning model that can predict the word about to be uttered by a subject based on their neural activity. The model achieved 55% accuracy using six channels of data and 70% accuracy using eight channels, comparable to other studies requiring electrodes over the entire cortical surface.
Columbia Engineering neuroscientists identified a specific neural mechanism in the human brain that enhances memory for emotional events. High-frequency brain waves in the amygdala and hippocampus are critical to this process, and disruptions can impair memory specifically for emotional stimuli.
Researchers developed HippoCamera, a new smartphone app that significantly improves memory recall by boosting attention to daily events. Users record videos and audio descriptions of everyday experiences, which are then replayed to reinforce memory consolidation.
A new study by Italian neuroscientists found that blind and deaf individuals' brains possess an innate functional architecture for integrating sensory information. This suggests that brain architecture can develop independently from sensory experience, adding weight to the 'nature versus nurture' debate.
Researchers found that abnormal methylation processes lead to disruption of gene expression essential for brain development in people with Williams syndrome. The study suggests targeting treatments to correct these disruptions.
A new study suggests that hormone replacement therapy (HRT) could help prevent Alzheimer's disease in women who are carriers of the APOE4 gene. The research found that HRT use is associated with improved memory and larger brain volumes among at-risk women. Early introduction of HRT during perimenopause may be particularly beneficial.
A new clinical trial report reveals that brain-computer interface implants are associated with a low rate of adverse events, similar to those experienced by patients with other chronic medical conditions. The study, which followed 14 participants for an average of 872 days, found no serious adverse events or device removals.
Researchers at the HSE Centre for Language and Brain found that a thicker corpus callosum is associated with less lateralization of language functions to the right hemisphere. The study used advanced neuroimaging methods, including fMRI, to measure brain activity while participants completed a sentence completion task.
A recent study suggests that the gut microbiome affects brain behavior, immune cells and neurodegeneration. Altering the gut microbiome could be an effective way to prevent or treat neurodegenerative diseases like Alzheimer’s.
A new study from Duke University found that a person's race affects their inclination to ask questions, with Black women asking half as many questions as White participants. This may impact diagnosis and treatment of communication impairments resulting from right hemisphere stroke.
A new study maps consciousness to brain geometry, revealing three cortical gradients that align with dimensions of consciousness. The findings have potential for developing brain-based diagnoses or assessments for neurologic patients.
Researchers have discovered a human-approved medication that can bring back 'lost' memories in mice, suggesting a potential new approach to treating age-induced memory problems or early-stage Alzheimer's disease. The study used optogenetic approaches and the asthma drug roflumilast to revive memories stored in the hippocampus.
A new AI model developed at USC accurately captures cognitive decline linked to neurodegenerative diseases like Alzheimer's much earlier than previous methods. The model analyzes MRI brain scans and detects subtle brain anatomy markers that correlate with cognitive decline, offering an unprecedented glimpse into human cognition.
A new USC study found that the buildup of amyloid beta protein in the brain is not directly linked to Alzheimer's disease, but rather a general change associated with aging. Researchers discovered higher levels of soluble Aβ protein in healthy brains, while insoluble fibrillary amyloid was more closely tied to poor brain health.
Researchers at UT Health San Antonio identified a new inflammatory trigger in Alzheimer's disease and progressive supranuclear palsy, involving 'jumping genes' that form double-stranded RNA mimicking viral infections. This discovery opens new doors for understanding astrocyte biology and their role in transposable element control.
Researchers have identified a previously unknown component of brain anatomy, dubbed SLYM, which acts as a protective barrier and immune monitoring platform. The discovery is expected to shed light on the glymphatic system's mechanisms and its potential role in brain diseases like Alzheimer's.
A survey of researchers and the public reveals a high percentage are in favor of proceeding with neuroscience research and brain-related information use. The general public expresses hopeful feelings about this research, while major differences exist between the two groups on ELSI topics.
A new study suggests that the brain's ability to identify a voice is linked to its ability to recognize faces, with a common brain center processing both visual and auditory information. This finding has important implications for understanding disorders where voice or face recognition is compromised.