Articles tagged with Human Brain
Researchers found structural and functional alterations in specific brain regions of individuals with opioid use disorder, including increased global connectivity. Women in the group had smaller medial prefrontal cortex volume compared to men.
Researchers developed nanocomposites that effectively reduce noise and improve signal transmission for brain pacemakers. The materials use a combination of graphene and clay to absorb and disperse energy, reducing the impact of external electrical fields on patients.
Researchers used machine learning to predict multiple types of intelligence from brain connections, with general intelligence performing best. The model's accuracy improved when trained on theory-driven connections, suggesting there are still unknown aspects of intelligence to discover.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
A USC study reveals that forming social ties relies on learning from positive outcomes, such as rewards, and tracking relational value. The findings help explain why we are drawn to certain people and how we navigate relationships, with implications for mental health and social behavior.
Marco Celotto and Simone Russo were awarded the Lagomarsino Prize for their groundbreaking research in neuroscience, which combined excellent scientific results with outstanding methods for data analysis, data management, and Open Science. Their work has led to pioneering discoveries on brain stimulation and its potential applications ...
Researchers at Boston University Alzheimer's Disease and CTE Center found that cumulative repetitive head impacts drive specific patterns of brain degeneration in chronic traumatic encephalopathy (CTE). The study also identified tau protein accumulation as a key mechanism in neuronal loss and synaptic changes.
The study reveals that electrical signals enhance calcium entry into cells, amplifying localized signals and extending their influence to neighboring cells through E-Ca coupling. This creates a synchronized system that adjusts blood flow both locally and across wider distances.
A new study by Reichman University reveals a digital treatment protocol improving spatial memory tasks and brain connectivity in aging adults. The innovative mobile app harnesses neuroplasticity to enhance navigational knowledge and potentially mitigate age-related cognitive decline.
A recent study by Duke-NUS Medical School has discovered that foetuses possess a functional immune system capable of combating infections before birth. This breakthrough finding suggests that fetuses are not defenceless against diseases and infections like Zika, which can cause serious health conditions such as microcephaly.
A new brain mapping technique has revealed fresh insights into how higher-order functions like language, thought, and attention are organised. Researchers used data from fMRI scans to create accurate models of brain activity and interactions between regions.
A new grant will support a five-year investigation into the role of the brain's reward network in two neurodevelopmental conditions. Researchers will use high-resolution fMRI scans to analyze how the reward network interacts with other parts of the brain in autism, ADHD, and co-occurring autism and ADHD.
Researchers have developed a network-based approach to understand how immune cells called microglia transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study identified three unique subtypes of harmful microglia that promote disease progression, with genetic signatures driving their behaviors.
Researchers linked genes to hallmark features like tau tangles and amyloid plaques, as well as other less understood brain changes. The study identified a genetic variant in the APH1B gene directly influencing tau tangle formation, and confirmed the APOE gene's role in granulovacuolar degeneration.
Researchers found that women who had both ovaries surgically removed before age 50 are at high risk of late-life Alzheimer's disease, with a fourfold increase in risk linked to the APOE4 allele. Hormone therapy reduces this risk by half in these women.
Researchers from Juntendo University discovered a four-step neural pathway involved in response inhibition, involving visual processing, sensory integration, action control, and execution of inhibition. The study aims to develop targeted therapeutic strategies for conditions like ADHD and obsessive-compulsive disorder.
A UT Health San Antonio study found that brain volume changes correlate with social behavior differences in psychiatric conditions such as autism spectrum disorder and schizophrenia. Tbx1 deficiency was associated with decreased brain volume in the amygdala and surrounding cortical regions, affecting desire for social interaction.
A USC-led study found that neurogenesis in adults supports verbal learning and memory, enabling people to have conversations. The discovery could lead to new approaches to restore cognitive function in patients with epilepsy and other conditions.
Scientists have created a living cell therapy that can navigate to specific organs using a
Scientists at St. Jude Children's Research Hospital found a link between the chromosomal disorder 22q11.2 deletion syndrome and schizophrenia, with malformations in the cerebellum causing Tbx1 gene loss leading to improper skull formation.
Researchers have identified structural grey matter differences in the brains of women with a history of peripartum depression compared to those without. The study found that hormone fluctuations during pregnancy and childbirth may be key to understanding this condition.
A new study reveals that glyphosate exposure in mice can cause lasting brain inflammation and accelerate Alzheimer's disease-like pathology, even after a significant pause from exposure. The herbicide's byproducts have been found to accumulate in brain tissue, raising serious concerns about its safety for human populations.
Researchers at UCSF found a brain signature of resilience in mice that suggests a new way to treat severe depression. Stress changes activity in the amygdala, distinguishing resilient from less resilient mice. By stimulating neurons, the team improved decision-making and reduced ruminating in less resilient mice.
A new optical fiber sensing system can track six biomarkers simultaneously and automatically provide crucial information on brain health. The technology has been successfully tested in lab experiments using animal brains and human cerebrospinal fluid samples, demonstrating its potential to monitor complications from traumatic injuries.
A recent study has identified Kif23 as a key regulator of embryonic brain development, highlighting its potential link to microcephaly. The research found that Kif23 is essential for neural progenitor cell proliferation and differentiation, with deficiency leading to decreased cell growth and increased apoptosis.
A new study published in the Journal of the American Heart Association found that Mexican American women are more likely to miss prescribed doses of stroke prevention medications. The study highlights sex-associated disparities in stroke care, particularly among racial and ethnic minorities.
A study published in the Journal of Neuroscience found that sleeping improves ability to remember new words and complex grammatical rules. Researchers tracked brain activity of participants learning a miniature language called Mini Pinyin while sleeping or awake, revealing significant improvements in those who slept.
A study found that skeletal muscle loss, particularly in the temporalis muscle, is associated with an increased risk of developing Alzheimer's disease dementia. Participants with smaller temporalis muscle size were more than twice as likely to develop dementia over a median follow-up period of 5.8 years.
A Baycrest study has found that high blood sugar may impair brain health even in people without diabetes. Researchers analyzed data from 146 healthy adults and found a correlation between high blood sugar levels and lower brain activity.
A new OHSU study reveals that the human ability to conceptualize numbers is rooted deep within the brain, specifically in the putamen region. This finding has significant implications for improving learning among math-challenged individuals and for neurosurgical interventions.
A new study will evaluate the benefits and risks of endovascular thrombectomy for patients presenting beyond 24 hours. The trial aims to provide deterministic evidence of clinical benefit due to addition of endovascular thrombectomy to standard medical care.
Research reveals transgender and gender-diverse preteens are 15% less physically active than cisgender peers, with 1,394 fewer steps taken daily. This disparity may be due to stigma and discrimination discouraging team sports participation.
Professor Lavretsky's pioneering work integrates conventional psychiatric treatments with mind-body interventions, developing novel therapeutic combinations for treatment-resistant depression and cognitive disorders. Her research has transformed approaches to mental health and aging, emphasizing whole person health and prevention.
Researchers uncovered how mutated PSEN2 accelerates disease progression in familial Alzheimer's disease by impairing synaptic function and disrupting cellular processes.
A Baycrest study reveals that degeneration of the thalamus, a brain area distinct from stroke lesions, contributes to post-stroke symptoms. Innovative non-invasive treatments targeting this area may improve or reverse these life-altering consequences.
A Northwestern University study found that gut microbes from large-brain primate species, such as humans and squirrel monkeys, can increase energy production in mice, while those from small-brain species like macaques store more energy as fat. This suggests a link between the microbiota and brain evolution.
Researchers found overlapping genetic underpinnings between rhythm-related skills and language-related traits, including dyslexia. The study identified 16 regions of the genome that overlapped between rhythm and language, suggesting a complex genetic architecture shared by these fundamental human traits.
A study published in Neurology found that children with multiple sclerosis from disadvantaged neighborhoods had greater brain inflammation and tissue loss. Social factors such as public health insurance, race, and parental education level were associated with worse MS outcomes.
A study by ULiège researchers reveals two distinct mechanisms behind neuronal degeneration, which act simultaneously to ensure reliable modulation of neuronal signals. This discovery sheds light on the principles of neuromodulation and has implications for improving artificial systems such as robots and AI devices.
A new study published in PNAS found that human brain size increased rapidly over millions of years, challenging long-standing ideas about brain evolution. The research analyzed ancient human fossils and found a steady, incremental 'software update' within each species.
Researchers found that people with CTE and a family history of mental illness had an average score of 19 on aggression, compared to 17 for those without. A higher risk was seen among participants who died between 40-59 years old, indicating a potential link between genetic and environmental factors.
A new study found that brain stimulation effectiveness is linked to individual learning abilities, not age. The study used atDCS on participants with optimal and suboptimal learning strategies, revealing accelerated accuracy improvement in suboptimal learners.
A new study in Nature identifies strategies for tying brain function and structure to behavior and health, improving the reliability of brain-wide association studies. By strategically selecting participants and collecting multiple scans, researchers can obtain more dependable results with fewer participants.
A study published in PLOS Biology found that great apes and adult humans alternate attention between two subjects when observing an event, similar to human language's agent-patient relationship. This suggests that the way brains order events evolved before language.
Researchers developed MoPEDE, a method combining genetic data and brain activity to pinpoint epileptic seizure origins. This approach offers deeper insights into epilepsy mechanisms, potentially leading to personalized treatments.
Researchers at ISTA used miniature 2D organs and rubbery silicone molds to study morphogen signaling dynamics during spinal cord development. The study found that BMP morphogen signaling gradients emerge quickly, then fade away, only to reappear again, shedding light on the complex process of tissue development.
Researchers developed a novel approach to deliver therapeutics into the brain, overcoming the blood-brain barrier. The BCC platform successfully reduced harmful gene activity in models of ALS and Alzheimer's disease, offering new possibilities for treating neurological and psychiatric diseases.
Researchers discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body. This finding paves the way for simpler and cheaper drugs to control obesity and weight gain.
Leila Nabulsi is expanding her research program to pinpoint brain pathways affected by bipolar disorder. She will leverage the ENIGMA consortium and advanced statistical methods to build a database of brain changes, potentially improving diagnosis and treatment.
Researchers used fitness tracker data and machine learning to detect bipolar disorder mood swings with 80.1% accuracy for depression and 89.1% accuracy for mania. The study's findings move the field toward personalized algorithms suitable for all patients, regardless of compliance or device access.
Researchers at DGIST have developed a fully embedded wireless brain neural signal recorder that enables real-time recording of brain neural signals in non-human primates. The system uses wireless power transmission and communication to record brain activity during natural behaviors, such as eating or moving freely.
A new study from Rice University and Houston Methodist reveals that NREM sleep enhances neuronal and behavioral performance by fostering brain synchronization and information encoding. Researchers replicated these effects through invasive stimulation, suggesting promising possibilities for future neuromodulation therapies.
A new Northwestern Medicine study found the 'lizard brain' is connected to newly evolved social cognitive network regions, which are involved in thinking about other people. This link helps shape the function of the social cognitive network by giving it access to the amygdala's role in processing emotionally important content.
The study found decreased NMDA receptors in synapses and increased extrasynaptic membranes in Alzheimer's patients, suggesting neuronal toxicity-related activity. The novel protocol allows for precise analysis of these receptors in human postmortem brains, paving the way for new therapeutic approaches.
A team of researchers at Georgia State University has made a groundbreaking discovery in understanding schizophrenia using fMRI scans. They identified unique spatial variation and enhanced sensitivity in the brains of patients with schizophrenia, offering an alternative way to identify early signs of the disorder.
Researchers from Michigan State University used brain-scanning tools to predict visitation patterns in urban environments. The study found that the brain's reward system can shape human behavior within cities, aiding in designing sustainable living spaces.
Researchers at Rutgers University have uncovered how various brain cell types work together to form large-scale functional networks in the human brain. The study found that certain cell-type distributions align with specific networks in the brain's cortex, highlighting a connection between cellular underpinnings and brain function.
A novel method has been developed to infer DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution. The study found over 1,850 sites of differential methylation specifically in prefrontal cortex neurons, linked to genes crucial for brain development.
Researchers found that recovery from anti-NMDAR encephalitis takes longer than previously thought, up to three years, with continued thinking and memory problems. The study also showed that participants who went back to school or work had better scores on well-being and processing speed.
Researchers examined 25 astronauts' cognitive performance over a 6-month ISS mission and found slower processing speed, working memory, and attention, but accuracy remained intact. No significant cognitive impairment or neurodegenerative decline was observed after the mission.