A clinical trial has shown that setmelanotide, a new drug, can achieve significant weight loss in people whose weight has become dysregulated following treatment for a brain tumor. The treatment resulted in a 20% reduction in BMI, with participants experiencing substantial health benefits.
SourcePrincess Máxima Center for Pediatric Oncology·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateJul 8, 2026
Researchers at Nagoya University identified the neural circuit responsible for timing torpor in mammals, which reduces body temperature and metabolism. The discovery provides new insights into how animals regulate energy use.
SourceNagoya University·JournalNature Communications·TypeExperimental study·DateJun 3, 2026
Researchers found significant loss of neurons in the locus coeruleus, a second critical region involved in arousal and muscle tone regulation. This finding suggests an immune-mediated process and challenges the prevailing explanation for narcolepsy with cataplexy.
SourceUniversity of California - Los Angeles Health Sciences·JournalNature Communications·DateApr 30, 2026
A collaboration between the University of Maryland and University of Concepción has discovered a previously unknown communication chain involving astrocytes and tanycytes that controls behavior. The study suggests that targeting the HCAR1 receptor in astrocytes could offer a novel approach to treating eating disorders.
SourceUniversity of Maryland·JournalProceedings of the National Academy of Sciences·DateApr 6, 2026
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers investigated brain mechanisms that maintain balance between intimidation and physical aggression in mice. Projections from the lateral hypothalamus to the dorsal raphe nucleus play a critical role in preserving this balance. Increasing pathway activity led to increased attacks, while inhibiting it decreased attack bites.
SourceUniversity of Tsukuba·JournaliScience·DateApr 1, 2026
A study published in Science reveals that microglia and the protein RANK are involved in regulating the hypothalamic-pituitary-gonadal axis, which controls fertility. The research found that suppressing RANK expression led to distorted reproductive function, including reduced sex hormones and hypogonadism.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalScience·TypeExperimental study·DateMar 12, 2026
A University of Houston researcher disputes a study claiming multilingualism promotes healthy brain aging, finding that wealth and healthcare systems may drive longevity instead. Hernandez argues that individual behavioral solutions, such as learning a language, are oversold and distract from structural factors that support healthy aging.
SourceUniversity of Houston·JournalBrain and Language·DateMar 9, 2026
Research found that breast cancer flattens corticosterone release in mice, reducing quality of life and increasing mortality. Disruptions to diurnal rhythms have been linked to stress responses like insomnia and anxiety in cancer patients.
SourceCold Spring Harbor Laboratory·JournalNeuron·DateDec 15, 2025
Researchers have identified the cells and connections underlying a fish's ability to dynamically change color to match its surroundings. The study found that specialized skin cells called melanophores control the color change, which helps the zebrafish evade predators by lightening its skin over tens of minutes.
SourceMax-Planck-Gesellschaft·JournalCurrent Biology·DateNov 16, 2025
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A research team, including Dr. Yong Xu, will use the grant to investigate genetic changes affecting hypothalamic pathways and their impact on metabolism and behavior in humans and animals. The study aims to unravel the precise way brain wiring controls instinctive behavior across species.
Research found that high-fat and high-carbohydrate diets are controlled by separate neural pathways in the brain. Neuropeptide Y neurons activate AMPK-regulated corticotropin-releasing hormone neurons to promote high-carb intake, while inhibiting melanocortin 4 receptor neurons to increase high-fat intake.
SourceNational Institutes of Natural Sciences·JournalMetabolism·TypeExperimental study·DateOct 22, 2025
A new study reveals the complex brain circuits involved in growth hormone release during sleep. The findings provide a map for understanding how sleep and hormone regulation interact, potentially leading to new treatments for sleep disorders and degenerative diseases.
SourceUniversity of California - Berkeley·JournalCell·TypeExperimental study·DateSep 8, 2025
Two ISTA Assistant Professors, Amelia Douglass and Ylva Götberg, have won 1.5 million euro ERC Starting Grants to explore how animals react to stress and the science behind binary-star stripping. Their research could lead to a better understanding of brain pathways disrupted in humans suffering from anxiety and stress.
SourceInstitute of Science and Technology Austria·DateSep 4, 2025
Bentz will investigate how maternal hormones shape behavior across generations in House sparrows, with implications for understanding animal adaptation. The research aims to identify gene networks that respond to early testosterone exposure and track changes from development through adulthood.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers discovered that stress activates neurons in the paraventricular nucleus of the hypothalamus, leading to impaired sleep and memory. Inhibiting these neurons reduced stress-related memory issues while slightly improving sleep.
SourceSociety for Neuroscience·JournalJNeurosci·DateJun 9, 2025
Researchers at University of Arizona Health Sciences identified a potential way to reduce female post-operative pain by inhibiting pituitary prolactin. Stress can increase circulating levels of prolactin, leading to worsened post-operative pain in women.
SourceUniversity of Arizona Health Sciences·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 20, 2025
A comprehensive review article synthesizes decades of research on stress hormone systems in primate brains, revealing key differences between rodents and primates. The findings highlight the importance of considering anatomical differences when developing treatments for stress-related psychiatric disorders.
SourceGenomic Press·JournalGenomic Psychiatry·TypeLiterature review·DateMay 13, 2025
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Dr. Seymour Reichlin's remarkable career spanned five decades, marked by scientific excellence, mentorship, and generosity. His influence on neuroendocrinology has been profound, with ongoing contributions at age 100 revealing new insights into Alzheimer's disease and ecstatic mysticism.
SourceGenomic Press·JournalBrain Medicine·TypeNews article·DateApr 29, 2025
A study published in Nature Metabolism reveals a novel mechanism connecting prolactin, estrogen, the brain, and metabolic adaptations during lactation. Hormonal changes during lactation lead to increased hunger and reduced fat-burning, which are sustained by a specific area of brain cells called ERα neurons.
SourceBaylor College of Medicine·JournalNature Metabolism·TypeExperimental study·DateApr 10, 2025
The study reveals conserved neural patterning mechanisms in mammalian hypothalamus development, tracing how brain cells emerge from neural progenitors during growth. The researchers identified four adaptive evolutionary divergences in human neurons, including a unique subtype and enhanced neuromodulation.
SourceChinese Academy of Sciences Headquarters·JournalDevelopmental Cell·DateApr 8, 2025
A study found that consuming sucralose alters brain activity related to hunger and increases appetite, especially in people with obesity. The sugar substitute changes how the hypothalamus communicates with other brain regions, including those involved in motivation, potentially leading to cravings and eating behavior changes.
SourceKeck School of Medicine of USC·JournalNature Metabolism·TypeExperimental study·DateMar 26, 2025
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Scientists at Brown University and Cincinnati Children's found that suppressing opsin 3 in the brain of mice makes them eat less. The study suggests that opsin 3 plays an important role in regulating food consumption via the melanocortin 4 receptor MC4R.
SourceBrown University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 14, 2025
Scientists at Indian Institute of Science have found how diverse neurons across different brain regions work together to control chronic pain in mice. The lateral parabrachial nucleus (LPBN) plays a key role in driving chemotherapy-induced peripheral neuropathy, allowing mice to cope with or suppress pain.
SourceIndian Institute of Science (IISc)·JournalPain·DateJan 8, 2025
Researchers at EPFL and Lausanne University Hospital have achieved a major milestone in treating spinal cord injuries by applying deep brain stimulation to the lateral hypothalamus. This therapy has improved mobility and independence in two individuals with partial SCI, demonstrating long-term neurological improvements.
SourceEcole Polytechnique Fédérale de Lausanne·JournalNature Medicine·DateDec 2, 2024
A team of scientists has pinpointed a critical neural circuit for female sexual rejection, revealing how the brain integrates signals to shape behavior. The ventromedial hypothalamus, specifically progesterone-sensitive neurons in the anterior VMH, play a crucial role in determining whether a female accepts or rejects mating attempts.
SourceChampalimaud Centre for the Unknown·JournalNeuron·TypeExperimental study·DateNov 25, 2024
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A high-fat diet can promote overweight and increase diabetes risk, but fat alone does not change the brain's hypothalamus. Other macronutrients like sugar may have more profound effects on AgRP neurons.
SourceDeutsches Zentrum fuer Diabetesforschung DZD·JournalScientific Reports·TypeExperimental study·DateOct 4, 2024
A recent study by FAU researchers reveals how the brain coordinates food intake to ensure we receive the right amount of energy. The hypothalamus, a control center in the brain, triggers behaviors like eating and satiety through a complex mechanism involving four teams of neurons that work together like relay runners.
SourceFriedrich-Alexander-Universität Erlangen-Nürnberg·JournalJNeurosci·DateSep 17, 2024
Research reveals a link between epigenetic factors and metabolic syndrome, highlighting the critical role of the hypothalamus in regulating energy balance. Studies show that maternal obesity can reprogram offspring's metabolism through epigenetic modifications.
SourceXia & He Publishing Inc.·JournalGene Expression·DateJul 30, 2024
Researchers found that patterns of neural activity in the hypothalamus predict performance in survival tasks, while associations with other brain regions were observed for hunting and escaping behaviors. The study provides new insights into how the human brain coordinates survival strategies.
SourcePLOS·JournalPLOS Biology·TypeComputational simulation/modeling·DateJun 27, 2024
Research found that higher light levels increase activity in the posterior hypothalamus, leading to improved cognitive performance during executive tasks. In contrast, lower light levels decreased activity in this region, negatively correlating with cognitive performance.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers found that middle-age obesity is caused by age-related changes in the shape of neurons in the hypothalamus, a region controlling metabolism and appetite. A protein called MC4R detects overnutrition and regulates metabolism to prevent obesity. Dietary restriction may help maintain brain anti-obesity systems as we age.
SourceNagoya University·JournalCell Metabolism·TypeExperimental study·DateMar 13, 2024
A new study published in Nature found that a distinct area on the underside of the hypothalamus influences longer-lasting avoidance behavior after being defeated. The research suggests that oxytocin plays a key role in this process, binding to receptors on brain cells and signaling danger.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature·DateJan 24, 2024
Researchers at Washington State University discovered that cannabis activates a set of cells in the hypothalamus, promoting appetite in mice. The study used calcium imaging technology to determine how brain cells responded to vaporized cannabis sativa.
SourceWashington State University·JournalScientific Reports·DateJan 16, 2024
Researchers discovered a critical communication pathway between the brain and fat tissue that contributes to aging. Activating specific brain cells improved energy production, physical activity, and lifespan in mice by 7%. The findings suggest potential interventions to maintain this feedback loop and slow aging effects.
SourceWashU Medicine·JournalCell Metabolism·DateJan 8, 2024
A recent study published in Nature Communications has identified a key brain molecule responsible for triggering overconsumption of comfort foods after stressful events. The lateral hypothalamic proenkephalin neuron plays a crucial role in driving threat-induced eating associated with negative emotional states.
SourceVirginia Tech·JournalNature Communications·TypeExperimental study·DateNov 30, 2023
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A Virginia Tech scientist has identified a molecule in the hypothalamus region of the brain linked to stress-induced emotional overeating. The discovery may lead to new therapy targets for alleviating emotionally triggered eating.
SourceVirginia Tech·JournalNature Communications·TypeExperimental study·DateNov 27, 2023
A team of researchers from Kyoto University found that the pituitary vasopressin system is crucial for building a robust circadian clock in the suprachiasmatic nucleus. This discovery has led to the development of potential treatments for jet lag, which currently target only the suprachiasmatic nucleus.
SourceKyoto University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateNov 23, 2023
Researchers at Imperial College London found that specific brain cells in the prefrontal cortex trigger mice to prepare for bed when tired, a behavior likely shared with humans. This hard-wired survival feature suggests that humans should prioritize sleep hygiene to maintain good health.
SourceImperial College London·JournalNature Neuroscience·DateSep 21, 2023
A new study in rodents reveals that infant cries prompt the release of oxytocin, a brain chemical controlling breast milk, in mothers. The study shows how sound information travels to the brain, triggering the hormone release, which continues for around five minutes.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature·TypeExperimental study·DateSep 20, 2023
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers have identified a cluster of neurons in the hypothalamus called GABRA5 that regulates energy expenditure. Astrocytes control this cluster, producing tonic GABA that inhibits it, leading to weight gain.
SourceInstitute for Basic Science·JournalNature Metabolism·TypeExperimental study·DateAug 31, 2023
Researchers found that individuals with higher body mass indexes have impaired connections between the hippocampus and hypothalamus, leading to an inability to control eating habits. The study suggests that targeting this brain circuit may lead to new treatments for obesity and related disordered eating conditions.
SourceUniversity of Pennsylvania School of Medicine·JournalNature·TypeRandomized controlled/clinical trial·DateAug 30, 2023
Researchers found that the hypothalamus, a key region controlling appetite, is larger in individuals who are overweight or obese compared to those with a healthy weight. The study suggests that increased volume may be linked to inflammation and altered hormone regulation.
SourceUniversity of Cambridge·JournalNeuroImage Clinical·TypeObservational study·DateAug 7, 2023
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
A recent study published in Nature Communications identified an important brain circuit for socially subjective reward valuation, finding that temporarily disconnecting the medial prefrontal cortex from the lateral hypothalamus reduces susceptibility to others' rewards but not individual expectations. This research has significant impl...
SourceNational Institutes of Natural Sciences·JournalNature Communications·TypeExperimental study·DateAug 4, 2023
Researchers at the University of Otago, Dunedin, New Zealand discovered a dahlia extract that improves blood sugar regulation without reported side effects in humans. The extract targets the brain's function required for blood sugar regulation by enhancing insulin function.
SourceHigher Education Press·JournalLife Metabolism·TypeExperimental study·DateJul 20, 2023
Researchers at ETH Zurich discovered that orexin neurons directly influence emotional state through pupil size. This finding opens new avenues for medical treatment and diagnosis of sleep disorders like narcolepsy and other neurological conditions.
SourceETH Zurich·JournalNature Neuroscience·TypeExperimental study·DateJul 11, 2023
Scientists at Karolinska Institutet have identified a group of nerve cells involved in creating negative emotional states and chronic stress. The neurons, which are sensitive to oestrogen levels, were mapped using advanced techniques such as Patch-seq, Neuropixels, and optogenetics.
SourceKarolinska Institutet·JournalNature Neuroscience·TypeExperimental study·DateJun 22, 2023
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
The ventral lateral preoptic area (VLPO) has a novel function in inducing arousal, contrary to its traditional role in promoting sleep. VLPO neurons form direct connections with orexin neurons in the LHA, leading to wakefulness induction.
SourceUniversity of Tsukuba·JournalJNeurosci·DateJun 5, 2023
Researchers found that eating small amounts of high-fat and sugar foods regularly rewires the brain to prefer these types of foods. The brain's dopaminergic system is activated, leading to a subconscious preference for rewarding food.
SourceMax Planck Institute for Biology of Ageing·JournalCell Metabolism·TypeExperimental study·DateMar 22, 2023
A new study found that loss of Menin in the hypothalamus drives physiological aging in mice, including cognitive decline and reduced lifespan. However, supplementation with the amino acid D-serine reversed these age-related changes, improving skin thickness and bone mass.
SourcePLOS·JournalPLOS Biology·TypeExperimental study·DateMar 16, 2023
Researchers found that leptin receptor neurons prioritize social interaction over eating and drinking in moderately hungry mice. This system can only regulate moderate hunger, but not strong hunger, which may contribute to why diets don't work.
SourceCell Press·JournalCell Metabolism·TypeExperimental study·DateFeb 23, 2023
Scientists found that chronic stress increases the activity of proopiomelanocortin (POMC) neurons, leading to behaviors such as anhedonia and depression. Inhibiting POMC neuron activity reduced these behavioral changes. The study suggests that POMC neurons play a key role in increasing susceptibility to stress-related behavioral problems.
SourceMedical College of Georgia at Augusta University·JournalMolecular Psychiatry·DateJan 24, 2023
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A study by Nagoya University researchers has identified EP3 neurons as crucial in maintaining a stable body temperature of 37°C in mammals. The discovery could lead to the development of technologies that artificially adjust body temperature to treat heat stroke, hypothermia, and obesity.
SourceNagoya University·JournalScience Advances·TypeExperimental study·DateDec 23, 2022
Research reveals TBX3 as a fate determinant controlling hypothalamic KNDy neuron development and puberty onset. Multiple TBX3 mutants fail to form phase-separated condensates, leading to delayed puberty in UMS patients.
SourceChinese Academy of Sciences Headquarters·JournalScience Advances·TypeExperimental study·DateNov 16, 2022
Researchers found that IGF1 gene therapy increases kisspeptin expression and GnRH release, and alters microglial cell numbers, suggesting a potential protective effect against reproductive decline. This could lead to new strategies for optimizing lifespan and combating age-related health problems in women.
SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateNov 16, 2022
A study published in Science Advances reveals that physical exercise triggers a neuromuscular circuit that links the production of interleukin-6 to muscle fat breakdown. This circuit is crucial for weight loss and has significant implications for obesity treatment.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalScience Advances·DateOct 26, 2022
DJI Air 3 (RC-N2)
DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
A research team has identified a specific cell group in the brain that regulates shifts in the sleep-wake rhythm caused by psychostimulants. The hypothalamic dopamine locus is responsible for modulating circadian rhythms and gates the effect of psychostimulants, leading to increased alertness and activity.
SourceMedical University of Vienna·JournalNature Communications·DateOct 11, 2022
Researchers at Eötvös Loránd University identified a novel neural pathway in the brain that processes touch information, which plays a crucial role in social behavior. The thalamo-hypothalamic neural pathway uses PTH2 as a neurotransmitter and facilitates friendly social interactions between rats.
SourceEötvös Loránd University·JournalCurrent Biology·DateSep 19, 2022
A new map of brain stem circuits controlling eating behavior could lead to better obesity treatments. The atlas, built from recent discoveries in mice and human studies, identifies two food intake-suppressing circuits in the brain stem, one causing nausea and another not.
SourceMichigan Medicine - University of Michigan·JournalNature Metabolism·DateAug 25, 2022
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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A new study published in Nature reveals that a small population of neurons near the base of the brain can induce symptoms of sickness, including fever, appetite loss, and warm seeking behavior. The researchers found these neurons have receptors capable of directly detecting molecular signals from the immune system.
SourceHarvard University·JournalNature·TypeExperimental study·DateJun 8, 2022
A joint research team reveals a distinct developmental transition for the neural microcircuit in the ventromedial hypothalamus (VMH), featuring dense electrical coupling and sparse chemical synapses. The study provides a solid microcircuit basis for understanding hypothalamic functions.
SourceChinese Academy of Sciences Headquarters·JournalCurrent Biology·DateJun 6, 2022