Articles tagged with Insular Cortex
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A KAIST research team has identified a key neural pathway involved in forming fear memories triggered by psychological threats. The pIC-PBN circuit processes psychological distress and drives fear memory formation, offering a significant advance in understanding how psychological distress is processed.
Researchers developed a new therapy that teaches patients to tolerate stomach and body discomfort, improving functional brain deficits linked to visceral disgust. The study showed improved outcomes for adolescents with low-weight eating disorders compared to traditional family-based treatment.
Research on mice exposes to cannabidiol during gestation shows altered behaviors and brain changes, affecting nerve cells involved in processing emotions. The study suggests a public health priority to understand CBD's impact on developing nervous systems.
A new AI-driven tool can accurately diagnose Lewy body dementia by analyzing changes in vocal emotional expressions. The study found that individuals with Lewy body dementia exhibited more negative and calmer emotional expressions compared to those with Alzheimer's disease and healthy controls.
This study analyzed resting state fMRI data to investigate salience network disruptions in schizophrenia. The analysis revealed weaker dorsal salience network connectivity and increased ventral salience network connectivity in patients.
A study by researchers at UNC School of Medicine found that chronic cocaine use alters the functional networks in the brain, including the default mode network and salience network. This disruption can make it harder for individuals to focus, control impulses, or feel motivated without the drug.
Researchers used low-intensity focused ultrasound to target the insula, a brain region associated with pain processing. The study found that participants experienced an average reduction in pain of three-fourths of a point, as well as decreased physical responses to pain-induced stress.
A new review highlights the current state of the art in autism research, using genetically modified mice to analyze the molecular and physiological mechanisms behind autism. The insular cortex is found to be crucial for emotions, empathy, and motivation in both mice and humans.
Researchers have developed a novel experimental platform that combines optical and fMRI techniques to study large-scale brain networks. The platform identified the anterior insular cortex as a key player in controlling the Default Mode Brain Network, which is active during daydreaming, memory retrieval, and envisioning the future.
Research found PIRI to be an independent predictor of infarct growth rate and 90-day outcomes in large-vessel occlusive stroke. The study suggests PIRI may help identify patients who could benefit from late-window endovascular thrombectomy.
Researchers identify 'thermal cortex' in posterior insular cortex of mice brains, finding specific cold-responding neurons for warmth and vice versa. The discovery sheds light on temperature perception and may help understand complex surface structures and brain diseases.
A multidisciplinary team at UVA Health will use deep brain stimulation to treat refractory neuropathic pain, aiming to modulate pain signals from the insula. The study may shed light on the fundamental nature of pain and identify biological indicators for effective treatment.
Research published in JNeurosci found that Gulf War veterans with chronic pain have changes in brain structure involved in pain processing, including larger frontal cortex areas and smaller insular cortices. These structural differences may contribute to the development of effective treatments for Gulf War Illness.
The insular cortex processes both positive and negative emotions and receives information from the body, including heart rate and breathing. In mice, the brain uses bodily signals to regulate fear, keeping it within a healthy range.
Researchers find that neurons in the insular cortex can induce inflammation in mice, suggesting a link between the brain and psychosomatic illnesses. The study suggests that 'remembering' an inflammatory response can reactivate it, opening new avenues for treating chronic inflammatory conditions.
Researchers at University of California San Diego School of Medicine identified the anterior insula's role in predicting and emotionally processing pain in HIV-DSP patients. The study suggests that reduced anterior insula activity or increased cingulate activity may improve pain outcomes for these patients.
A new Dartmouth study found that a neural code shared across brains is responsible for recognizing familiar faces, including social and personal information. The study used hyperalignment to align brain responses into a common space, revealing high decoding accuracy in areas outside of visual processing.
A new study from Michigan Medicine researchers identifies the anterior insular cortex as a key area in the brain that acts as a filter, allowing only the most important sensory information to enter conscious awareness. This gate-like structure regulates brain network transitions and plays a crucial role in conscious access.
Researchers used fMRI to measure brain activity in risk circuits, accurately forecasting stock prices based on average group activity. Prior trends and individual choices failed to predict dynamics.
Research using neuroimaging found that white conservatives exhibit higher sensitivity to racial ambiguity in the anterior insula, leading them to overcategorize mixed-race faces as Black. This effect is linked to an affective reaction to racial mixing rather than a sensitivity to Blackness.
A new study by University of Nebraska-Lincoln psychologist Ingrid Haas found that humans process politically incongruent statements differently, with stronger neurological responses for inconsistent positions. Participants showed increased activity in brain regions involved in cognitive function when reading statements deviating from p...
A research team at Kobe University has identified 'social cells' in the brain related to social behavior, including Social-ON cells that activate during social interactions. The study found that these cells were active when a stranger mouse was present, regardless of location.
Neuroscientists at Ruhr-University Bochum have found that the thalamus plays a key role in decision-making during learning, while the insular cortex is active when participants make correct or incorrect decisions. This suggests that expectations influence brain activity and sensory perception.
Researchers at Arizona State University found that activating the anterior insula restored prosocial behaviors in animals with opioid addiction, a potential breakthrough in treating social behavioral deficits. The study used chemogenetic methods to selectively activate the brain region involved in both prosocial and addictive behaviors.
Researchers at Max Planck Institute describe different emotional facial expressions in mice, linking them to specific brain regions and emotions. The discovery enables the investigation of emotional mechanisms and their relationship with neuronal activity.
Researchers mapped CB1R mRNA expression in male and female mice, revealing distinct patterns in brain regions associated with Parkinson's disease, maternal behaviors, and the estrus cycle. The study provides a foundation for understanding sex differences in physiological and pathological brain functions related to cannabinoids.
Researchers at Beth Israel Deaconess Medical Center discovered that the insular cortex plays a crucial role in assessing and predicting physiological states. The study's findings provide potential new avenues for addressing diseases such as eating disorders, obesity, and drug addiction by targeting the brain's reward system.
A study by Northwestern University found that sleep-deprived individuals are more likely to choose high-energy dense foods due to an imbalance in brain regions receiving food signals. The researchers suggest that paying attention to our nose's influence on food choices may help alleviate unhealthy snacking habits.
A study found that microgravity impacts brain connectivity in cosmonauts, changing sensorimotor functions like movement and body position perception. The brain develops an auxiliary system relying on visual and tactile feedback to compensate for limited vestibular input.
A new study found that stimulating the brain's dorsal anterior insula triggers an ecstatic aura in epileptic patients. This region is proposed to be a key area for elicit symptoms of altered consciousness and ecstasy-like experiences. The findings provide additional support for its role in human consciousness.
The insular cortex sends warnings to brain areas involved in threat learning, enabling animals and humans to avoid future harm. This process is crucial for survival and involves the encoding of pain in the brain.
Researchers have discovered a specific area in the insular cortex of the brain that responds to sweetness stimulation on the tongue, revealing a complex taste map in humans. This 'sweet spot' is distinct from other tastes like sour, salty, and bitter.
Researchers discovered significant differences in neural processing between self-touch and touch from others at the cortical and spinal cord levels. This finding has implications for understanding perception and social behavior, highlighting the brain's unique response to self-produced versus external tactile input.
Researchers identified the insula as a brain area linked to opioid-related social isolation in rats. Activating this region may help revive social behavior in opioid addicts, potentially improving recovery outcomes.
A recent study published in JNeurosci found that activation of the anterior insular cortex is a key predictor of relapse after abstinence in male rats. This finding has implications for understanding the neurobiology of relapse and may inform preventative strategies for alcohol use disorder in humans.
Researchers have mapped the feeling of cool touch to the brain's insula in a mouse model, providing an experimental model for studying conditions like pain and hypersensitivity. The study found that the region was activated in mice with functional TrpM8 receptors, suggesting a highly specific response to cold exposure.
A study using MRI scans found variations in the volume of the insula brain region in transgender women, which may be linked to body dysphoria and discrimination. The research suggests that these differences may begin during gestation and cannot be explained by hormone treatment.
Research suggests that the brain's insular cortex mediates approach and avoidance responses to others in distress. The hormone oxytocin plays a crucial role in regulating this process, influencing social affective behaviors.
Researchers found greater grey matter volume in brain regions associated with auditory perception and emotional processing in individuals with high noise sensitivity. This suggests that noise sensitivity may require more neural resources to process sound, potentially related to self-awareness of noise-induced sensations.
A new study found that the insula plays a major role in generating spontaneous neuronal bursts in preterm babies, essential for strengthening brain connections. The bursts are also linked to healthier cognitive skills and reduced risk of cerebral palsy.
A study by neuroscientists at Duke and Stanford University found that multiple brain regions collaborate to produce empathetic decision-making in rats. The results clarify conflicting findings on the role of specific brain regions in guiding antisocial behavior, suggesting a more complex neural context.
Researchers at Beth Israel Deaconess Medical Center identify a pathway by which neurons driving hunger influence distant areas of the brain involved in decision-making. They found that visual cues associated with food trigger activation of specific neurons in the insular cortex, particularly in hungry mice.
Researchers used virtual reality to test participants' willingness to help others, finding that 65% chose to rescue an injured person despite the risk to themselves. Altruistic individuals showed a larger anterior insula, linked to social emotions processing, and higher empathic concern.
Researchers found increased brain activity in the insula and frontal cortex of problem gamblers when exposed to gambling cues. The study suggests that targeting the insula could be a promising approach for treating problem gambling.
A recent study found structural differences between the sexes in one part of the insula, a brain region involved in emotion processing. This difference may help explain why girls are more likely to develop PTSD than boys after experiencing trauma. The findings suggest sex-specific treatments for traumatic stress and emotion dysregulation.
Researchers at UCLA found opposite responses in the right front of the insular cortex between men and women, a critical area for emotions and blood pressure control. The study suggests differences in brain structure and function might contribute to varying clinical symptoms in medical disorders.
Research at Georgia State University found that increasing difficulty in making decisions based on sensory evidence boosts activity in the insular cortex. The study sheds light on how this brain area processes sensory information and drives behaviors.
Researchers at the University of Miami studied dynamic functional network connectivity in the insular cortex, revealing unique and overlapping profiles of its subdivisions. The findings suggest that changes in connection patterns between brain areas may contribute to the region's flexibility in multiple cognitive processes.
A new study uses real-time fMRI-based neurofeedback to help kids control their emotions, improving regulation and preventing future mental health issues.
Studies suggest that the insular cortex, damaged during a stroke, can lead to increased likelihood of quitting smoking and reduced withdrawal symptoms. Smokers who experienced strokes in this area were almost twice as likely to quit smoking compared to those with strokes in other parts of the brain.
Researchers at Wake Forest Baptist Medical Center identified brain regions activated during mismatches between expected and experienced pain. The parietal lobe and insular cortex were found to be involved in processing real-time mismatches.
A study found that smokers who quit successfully had greater connectivity between the insula and somatosensory cortex compared to those who failed. This suggests that targeting this neural pathway could be a strategy for improving smoking cessation outcomes. The researchers hope their findings will guide the development of new treatments.
A new brain imaging study has identified a specific brain area, the dorsal posterior insula, directly related to pain intensity. This discovery could help detect pain in people with limited communication abilities.
A review of neuroimaging studies suggests that areas of agreement exist in psychiatric diagnoses, particularly regarding the integrity of the anterior insula/dorsal anterior cingulate network. This network is associated with executive function deficits seen across various diagnoses. The study analyzed 193 peer-reviewed articles and fou...
The insula is essential for selecting salient stimuli, and dysfunction can lead to deficits in attention, social, and cognitive processes. Mapping the structure and function of the insular cortex may provide targeted treatments for developmental and degenerative disorders.
A study found that preschoolers with depression had a smaller right anterior insula, which predicts future bouts of depression. Excessive guilt in preschool years is also linked to brain changes and increased risk of recurrent depression.
Researchers at EPFL successfully recreated the ghost illusion in the laboratory by altering sensorimotor brain signals. This phenomenon is common to many cultures and can be observed in people with neurological or psychiatric disorders, such as epilepsy.
Scientists discovered consistent alterations in integrative processing of the insular cortex across autism mouse models, with a disturbed balance between excitation and inhibition. Pharmacological interventions, such as Diazepam, restored sensory integration capacity and reduced stereotypic behaviors.
Researchers at Caltech and Virginia Tech found that wise traders receive an early warning signal from their brains before price bubbles form in experimental markets. These 'irrational exuberance' individuals buy aggressively during the bubble, while smart traders sell early, causing the bubble to burst and earning them more money.
Research published in PNAS identifies the insula as a key brain region disrupted in individuals with gambling addiction. The study reveals that problems gamblers are more susceptible to cognitive distortions, such as the gambler's fallacy, due to insula hyperactivity.