Scientists discovered consistent alterations in integrative processing of the insular cortex across autism mouse models, with a disturbed balance between excitation and inhibition. Pharmacological interventions, such as Diazepam, restored sensory integration capacity and reduced stereotypic behaviors.
SourceMax-Planck-Gesellschaft·JournalNeuron·DateJul 31, 2014
Researchers at Caltech and Virginia Tech found that wise traders receive an early warning signal from their brains before price bubbles form in experimental markets. These 'irrational exuberance' individuals buy aggressively during the bubble, while smart traders sell early, causing the bubble to burst and earning them more money.
SourceCalifornia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateJul 7, 2014
Research published in PNAS identifies the insula as a key brain region disrupted in individuals with gambling addiction. The study reveals that problems gamblers are more susceptible to cognitive distortions, such as the gambler's fallacy, due to insula hyperactivity.
SourceUniversity of Cambridge·JournalProceedings of the National Academy of Sciences·DateApr 7, 2014
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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A study published in Neural Regeneration Research found that experimental low back pain altered the functional connections between the insula and default mode network, affecting regions involved in cognition and emotion. The findings suggest a crucial role of these brain regions in pain processing.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateApr 3, 2014
A UCLA study suggests that young adult smokers may experience physical changes in their brains due to cigarette smoking, which could explain why adults who began smoking at a young age stay hooked on cigarettes. The researchers found that brain structure changes were linked to the amount of smoking exposure and nicotine dependence.
SourceUniversity of California - Los Angeles·JournalNeuropsychopharmacology·DateMar 3, 2014
A new study found that gamblers' brains exhibit similar increases in theta activity to wins and near-misses, particularly in the insula and orbitofrontal cortex. This response is associated with gambling severity and susceptibility to problem gambling. The research suggests that brain responses to near-misses resemble those to actual w...
SourceUniversity of Exeter·JournalNeuroImage·DateFeb 25, 2014
A recent meta-analysis of 20 years of neuroscience research reveals significant sex differences in brain structure, with males on average having larger total brain volumes and higher tissue densities in certain regions. Females, on the other hand, have higher density in the left frontal pole and larger volumes in other areas.
SourceUniversity of Cambridge·JournalNeuroscience & Biobehavioral Reviews·DateFeb 11, 2014
Researchers at the University of Nottingham have discovered a faulty 'switch' between brain regions that may cause psychotic symptoms in people with schizophrenia. The study suggests that detecting this disconnection could help identify patients with the condition, and potentially lead to more effective treatments.
SourceUniversity of Nottingham·JournalNeuron·DateAug 21, 2013
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Research found that teens with anorexia nervosa had larger insula and orbitofrontal cortex brain areas, which may contribute to their ability to starve themselves. These brain regions process taste and body perception, potentially leading to a distorted sense of hunger and fullness.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJournal of the American Academy of Child & Adolescent Psychiatry·DateAug 21, 2013
A study led by Royal Holloway University researcher Carolyn McGettigan discovered brain regions involved in impersonations and accents. The team found that voice changes engage the left anterior insula and inferior frontal gyrus, while accent comparisons activate areas in the posterior superior temporal/inferior parietal cortex.
SourceRoyal Holloway, University of London·JournalJournal of Cognitive Neuroscience·DateJun 18, 2013
A new biomarker has been identified to predict which type of depression treatment is most likely to be successful, either therapy or medication. The study used pre-treatment brain scans to identify a pivotal predictor of outcomes from two standard forms of depression treatment: cognitive behavior therapy (CBT) or escitalopram.
SourceNIH/National Institute of Mental Health·JournalJAMA Psychiatry·DateJun 12, 2013
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A new UCLA study suggests that older adults' brains are less active in the anterior insula region, which is linked to disgust and detecting dishonest faces. This reduced activity makes it harder for older adults to recognize untrustworthy faces, leading to increased vulnerability to financial exploitation.
SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateDec 3, 2012
Researchers found that serotonin release in the visceral insular cortex is responsible for nausea. This discovery may lead to better understanding and treatment of nausea and vomiting caused by cancer chemotherapy.
Researchers study a person with extensive brain damage to regions believed critical for self-awareness, finding he remains self-aware despite damaged areas. The study suggests that self-awareness emerges from distributed interactions among networks of brain regions, not confined to specific areas.
Researchers at Max Planck Institute discover von Economo neurons in macaque monkeys, suggesting a primitive form of self-awareness. The finding opens new avenues for studying brain regions involved in human self-awareness and mental disorders like autism.
SourceMax-Planck-Gesellschaft·JournalNeuron·DateMay 21, 2012
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers aim to break nicotine addiction by blocking hypocretin-1 receptors, which play a key role in driving desire for more nicotine. The study has the potential to provide a significant breakthrough in treating tobacco abuse and preventing relapse.
Researchers found that the insular cortex, linked to social preferences and altruism, plays a key role in egalitarian behavior. The study provides neural support for Adam Smith's 'theory of moral sentiments' and suggests a broader view of morality as connected to environmental relationships.
SourceNew York University·JournalProceedings of the National Academy of Sciences·DateApr 9, 2012
Researchers found abnormal development of the insula circuit hub is rooted in genes and causes overly friendly yet anxious behavior in individuals with Williams syndrome. The study uses neuroimaging to pinpoint the suspect brain area in people with the disorder, revealing structural and functional abnormalities.
SourceNIH/National Institute of Mental Health·JournalProceedings of the National Academy of Sciences·DateMar 20, 2012
Long-term meditators have larger amounts of cortical gyrification, indicating improved neural processing and information processing. The study also found a positive correlation between meditation years and insular gyrification, supporting the idea that meditation enhances regional brain structure.
SourceUniversity of California - Los Angeles·JournalFrontiers in Human Neuroscience·DateMar 14, 2012
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers discovered that nerve impulses from muscles inhibit motor areas in the brain, leading to muscle fatigue. The insular cortex plays a key role in regulating muscle performance, with increased activity preceding fatigue.
SourceUniversity of Zurich·JournalEuropean Journal of Neuroscience·DateDec 5, 2011
A recent MRI study published in Molecular Psychiatry found that depression frequently uncouples the brain's 'hate circuit', which includes regions involved in risk and action responses, reward and emotion processing. This disruption may lead to impaired ability to control social interactions and increased self-loathing.
SourceUniversity of Warwick·JournalMolecular Psychiatry·DateOct 4, 2011
Researchers investigate how the insula integrates affective and cognitive processes, and how neural systems develop with age. They also examine the role of vision in auditory and tactile integration, and find that vision plays a crucial role in developing this integration.
SourceAssociation for Psychological Science·JournalPsychological Science·DateJan 21, 2011
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers found that individuals can learn to control the activity of specific brain regions when receiving fMRI feedback signals. The study, published in Biological Psychiatry, used functional magnetic resonance imaging (fMRI) to assess visual emotional stimuli and demonstrated the ability to modulate the response to aversive stimuli.
SourceElsevier·JournalBiological Psychiatry·DateSep 9, 2010
Barrow scientist A.D. Bud Craig is leading the global conversation about the insula, a hidden lobe of the brain involved in virtually every human emotion and behavior. The latest research indicates that the insula plays a crucial role in conditions such as addiction, anxiety, depression, and schizophrenia.
SourceSt. Joseph's Hospital and Medical Center·JournalBrain Structure and Function·DateJul 7, 2010
Researchers found two independent pathways contributing to feeling one's own heartbeat, contrary to prior assertions. The study used a rare neurological patient and healthy comparison participants to confirm the existence of these pathways, which could have implications for emotion and self-awareness.
SourceUniversity of Iowa·JournalNature Neuroscience·DateNov 2, 2009
Duke University researchers found that nicotine sends signals directly to sensory systems by several pathways, similar to how taste is perceived. They also discovered a previously unknown link between nicotinic acetylcholine receptors and activity in the insula region.
SourceDuke University Medical Center·JournalProceedings of the National Academy of Sciences·DateJan 22, 2009
Researchers at Scripps Florida found that blocking hypocretin-1 receptors significantly decreased nicotine self-administration and motivation in rats, suggesting a potential target for developing new smoking cessation treatments. The study highlights the importance of hypocretin-1 receptors in regulating nicotine reward and motivation.
SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateNov 24, 2008
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Researchers at UCL found a 'hate circuit' in the brain that is distinct from those related to love, fear, and aggression. The study reveals that the 'hate circuit' involves structures in the cortex and sub-cortex that are also activated by romantic love, but with a different pattern of activity.
SourceUniversity College London·JournalPLOS ONE·DateOct 28, 2008
Researchers found that the same brain regions are activated when observing facial expressions of disgust in others and experiencing it oneself. This study suggests that reading a book can elicit emotional responses comparable to those experienced while watching a movie, thanks to the shared brain activity patterns.
Studies revealed that people's brains respond differently to unfairness, with the orbital frontal cortex reacting to giving and the insula processing inequity. The findings suggest that a basic impulse to be fair is hardwired in humans, driven by emotional responses.
SourceCalifornia Institute of Technology·JournalScience·DateMay 28, 2008
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A study using fMRI scans found that people prioritize equity over efficiency in allocating donations, with the brain responding differently to both. The insula region was activated by changes in equity, while the putamen responded to efficiency, with the caudate integrating both factors after a decision was made.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalScience·DateMay 8, 2008
Researchers found that higher levels of brain activation in the anterior insula region can help individuals learn to avoid losses and financial risks, but excessive activity may be problematic. A healthy amount of anxiety grants survival value, but too much can lead to excessive worry and clinical conditions.
SourceAssociation for Psychological Science·JournalPsychological Science·DateApr 3, 2008
Chilean researchers have identified a brain region that plays a role in drug craving in amphetamine-addicted rats. The insular cortex processes information about the body's physiological states and guides behavior, indicating its potential as a target for treating drug addiction.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateOct 25, 2007
Researchers found that damage to the insula, a brain region linked to emotion and feelings, enables smokers to quit instantly. The discovery opens new directions for therapies targeting this specific region.
SourceUniversity of Southern California·JournalScience·DateJan 25, 2007
Research has found that brain damage to a specific area called the insula may help smokers quit by eliminating their addiction to nicotine. Twelve out of thirteen participants who experienced this type of damage were able to quit smoking without any reported struggles.
SourceNIH/National Institute on Drug Abuse·JournalScience·DateJan 25, 2007
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Researchers found that brain damage to insula region in smokers can completely eliminate the body's urge to smoke. Damage to this structure may offer leads for new therapies to help smokers quit or monitor their progress with existing treatments.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateJan 25, 2007
Research suggests that a specific gene variant linked to aggression impairs the brain's ability to regulate impulses and emotions, particularly in males. This impairment can lead to increased reactivity in the fear hub and reduced activity in higher brain areas that regulate emotional responses.
SourceNIH/National Institute of Mental Health·JournalProceedings of the National Academy of Sciences·DateMar 20, 2006
A new study found significant gray matter loss in the insular cortex and basal ganglia of advanced heart failure patients. The insular cortex was affected on both sides, with greater loss on the right side, while basal ganglia damage was also observed.
SourceAmerican Physiological Society·JournalJournal of Applied Physiology·DateSep 23, 2003
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A UC Davis researcher has discovered that damage to the insula region is a crucial impediment to motor control necessary for words and sentences. The insula, located deep within each hemisphere, is about two inches wide and contains a small area critical for coordinating speech sounds.