Articles tagged with Palate
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new technique for reconstructing the palate after tonsil cancer surgery has been shown to maintain patients' ability to speak clearly and eat most foods. The technique, developed at Michigan Medicine, separates the mouth from the nasal cavity and closes during swallowing, allowing patients to recover their complex throat functions.
Researchers have successfully developed echolocation in humans, allowing blind individuals to identify objects and navigate their surroundings. The technique involves producing specific tongue clicks to detect echoes, with results showing potential for practical applications beyond aiding the visually impaired.
A genetic variant on chromosome 8 is found to occur significantly more frequently in people with cleft lip and palate than in the control group. The study suggests that genes may play a far more important role in the formation of clefts than previously thought.
Researchers uncover how opposing genetic forces determine the correct pattern of tooth formation in mammals, revealing a potential pathway for tooth regeneration and combating birth defects. The study's findings suggest that careful regulation of competing pro- and anti-tooth initiation signals controls the sequence of tooth development.
A new study uses video imaging to reveal dynamic changes in airway structure during sleep and wakefulness, providing valuable insights into obstructive sleep apnea. The technique shows that the soft palate is more elongated and angled in patients with sleep apnea, even when they are awake.
The American Society of Plastic Surgeons is hosting medical mission trips in Central and South America to provide reconstructive surgery to children born with cleft lip and palate. The trips aim to not only repair the physical condition but also restore their lives by educating local physicians.
Researchers have identified a genetic variant associated with isolated cleft lip, which affects approximately one in five cases. The study found that the variant disrupts proper expression of the IRF6 gene, leading to disruptions in AP2 binding and contributing to the development of cleft lip.
Researchers from the University of Pittsburgh School of Dental Medicine have identified a series of genetic mutations associated with significant risk for cleft palate and other dental abnormalities. The study, published in Genetics in Medicine, analyzed DNA sequences from over 500 individuals and found more than a dozen gene mutations...
Researchers at USC School of Dentistry have discovered a new pathway that contributes to palate formation, bypassing the TGF-ß signaling molecule. This finding has implications for understanding cleft palate, tooth development, and diseases like cancer.
Researchers have found that delaying gum tissue closure improves outcomes for cleft palate patients. The study, led by Dr. Damir Matic, involved 136 children and found that closing the cleft at 8-9 years old prior to canine tooth eruption leads to better facial growth and reduces damage.
Researchers at the University of Oregon have discovered a previously unknown mechanism for cleft palate, a common birth defect. By studying a genetic mutation in zebrafish, they found that microRNA Mirn140 regulates the expression of Pdgf, a growth factor involved in cell signaling.
A recent global surgical mission successfully treated 39 Zimbabwean children with cleft lip and palate without complications. The key to effective care lies in training and continuing education of local physicians, a crucial step towards improving the socioeconomic conditions in Zimbabwe.
University of Iowa researchers have discovered new genetic mutations associated with non-syndromic cleft lip and palate, a common form of the condition. The findings may eventually help clinicians predict a family's risk of having more children with the condition.
Researchers at Stanford University School of Medicine have developed a technique to prevent cleft palates in fetal mice by injecting pregnant mothers with a small molecule. This breakthrough raises hopes that similar vaccination-type techniques may one day be used to prevent many types of human birth defects.
A new study found that folic acid supplements can substantially reduce the risk of isolated cleft lip with or without cleft palate in babies. Researchers discovered that taking 0.4 milligrams of folic acid per day during pregnancy can lower this risk by one-third.
Researchers identified IRF6 as a key gene causing cleft lip and palate disorders. The team also discovered that targeting this gene during pregnancy could lead to normal skin cell development.
Researchers at the University of Iowa identified a crucial role for IRF6 gene in skin development, which may lead to new treatments for cleft lip and palate. The study found that IRF6 regulates keratinocyte proliferation and differentiation, shedding light on this critical cell type.
Researchers identified a new gene, SUMO1, as a potential cause of cleft lip and palate when underexpressed. The discovery links individual genes to shared protein networks, providing a promising new lead in understanding the complex genetic mechanisms behind this birth defect.
Researchers have identified a genetic factor leading to forehead and frontal bone malformations, which can cause severe craniofacial defects. A potential therapy using FGF supplements may help prevent these defects in embryos with missing TGF-beta genes.
Researchers at the Mayo Clinic have developed a new method to repair cleft palates using distraction osteogenesis, which gradually lengthens bone and soft tissue. The technique has shown promising results in animal studies, with some degree of bony closure observed in most treated animals.
Researchers at the University of Manchester are exploring the role of p63 in cleft palate development. By investigating how this protein works during normal development and how it is disrupted in cleft palate, the study aims to improve understanding of the condition and potential therapies.
A new gene test can predict a child's risk of having an isolated cleft lip and palate, allowing parents to make informed decisions about future pregnancies. The test, based on distinct mutations in the IRF6 gene, has been shown to be effective in predicting the birth defect with approximately 12% accuracy.
A new study has identified a gene variant linked to cleft lip and palate, with implications for genetic counseling and treatment options. The discovery brings us closer to understanding the multiple genetic factors underlying these serious birth defects.
Researchers have developed a new gene test that can identify the risk of isolated cleft lip and palate in 12% of cases, opening up new possibilities for families affected. The test detects specific sequence variations associated with an increased chance of a child being born with a cleft.
Fetal MRI is less dependent on variables like amniotic fluid volume and fetus position compared to sonography, making it a more reliable method for detecting cleft lip and palate. Soft palate defects can also be visualized on fetal MRI, which is essential for predicting potential complications after birth.
A team of researchers discovered a specific genetic mutation, Tbx10, responsible for causing cleft lip and palate in mice. This finding suggests that similar mutations may exist in humans, shedding light on the complex development of facial features.
Research reveals that children with narrow retropalatal air spaces have more severe SDB due to significantly larger tonsil and soft palate CSAs. The study found a significant correlation between OAHI and oropharyngeal volume, indicating the importance of pharyngeal geometry and soft tissue anatomy in determining SDB severity.
A study published in Nature Genetics identified the T-box 22 gene as the cause of a rare form of cleft palate. The gene's mutation leads to catastrophic effects on protein production, resulting in the birth defect. The discovery may lead to prenatal therapeutic interventions for cleft palate.
Researchers developed a new outpatient treatment for snoring that uses radiofrequency energy to create multiple lesions in the soft palate, reducing vibrations and improving effectiveness. The study showed significant reduction in snoring and increased success rates compared to single lesion methods.
A new therapy, using a CPAP device, reduces hypernasal speech in people with repaired cleft palates by strengthening the muscles of the soft palate. The study, conducted on 43 subjects aged under 19, shows significant improvement after eight weeks of treatment.
A new study by Michigan Medicine researchers found that women who smoke during pregnancy are 50-70% more likely to give birth to a baby with cleft lip or palate. The risk increases with the number of cigarettes smoked daily, even after controlling for factors like mother's race, age, and education level.
A team of UCSF scientists has identified a key role for the Epidermal Growth Factor Receptor (EGFR) in regulating palate closure during fetal development. Disruption of EGFR function is linked to the formation of cleft palates, which occur when the palate fails to properly fuse.