A clinical study in Birmingham has found that nipocalimab can improve the survival rate of unborn babies with rare fetal anaemia. The majority of pregnant patients who received nipocalimab gave birth at or after 32 weeks without needing an intrauterine transfusion, resulting in a perinatal survival rate of 92%.
An experimental mRNA vaccine against CMV elicited promising immune responses, outperforming a previous vaccine candidate in preventing the virus from infecting epithelial cells. The new vaccine may protect adults against CMV, potentially preventing women from passing the infection to their babies during pregnancy.
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Researchers found that pregnant women with very low titers of anti-Ro antibodies are not at risk for fetal atrioventricular (AV) block, a serious disorder affecting the heart's electrical system. In contrast, high-titer antibody pregnancies can benefit from ambulatory fetal heart rhythm monitoring to detect AV block.
Researchers found novel autoantibodies implicated in hypertensive disorders of pregnancy, fetal growth restriction, and recurrent pregnancy loss. These autoantibodies are also associated with infertility and endometriosis-associated infertility.
Researchers found that hydroxychloroquine significantly reduces the recurrence rate of congenital heart block in subsequent pregnancies, regardless of health status. The study evaluated 74 mothers who had a previous child with congenital heart block and were exposed to HCQ during pregnancy.
BufferGel, a vaginal microbicide, maintains normal vaginal acidity to kill sperm and germs, preventing pregnancy. The compound is currently in advanced clinical trials for its ability to block HIV transmission.
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A Johns Hopkins study found that over 1 in 5 neurologists and obstetricians had patients with epilepsy who developed unwanted pregnancies due to anti-epilepsy drugs interfering with birth control pills. Increasing birth control medication levels or switching to non-interfering medications can reduce the risk of unplanned pregnancy.