Articles tagged with Skeleton
Researchers at EPFL developed a 3D printable scaffold to support fast bone growth using a room-temperature process with enzymes. The resulting bone-like porous scaffolds can become load bearing within just 7 days, showing promise for bone repair applications.
A team at The University of Osaka has identified a signaling molecule called FGFR3 and a pathway called CREB as key in regulating bone growth. Cells carrying the genetic mutation associated with achondroplasia accumulate in the resting zone and show abnormal behaviors, which included abnormal patterns of division and migration.
Researchers found that hormone treatment reduces abnormal nerve invasion and improves chronic back pain by limiting nerve growth inside damaged spinal tissue. The study suggests that parathyroid hormone can reverse the process by activating natural signals.
Researchers at Lund University developed a universal method for creating cell-free cartilage structures that guide bone repair without triggering strong immune responses. The successful test in animal models paves the way for human trials and the potential to transform the future of bone transplantation.
A new study identifies shared genetic factors influencing both coronary artery calcification and bone mineral density, suggesting common underlying biology rather than a direct causal link. The findings highlight potential targets for interventions supporting both cardiovascular and skeletal health as people age.
A new international study identifies several protein families potentially involved in bone remodeling and highlights their role in shaping bone structures through mechanoadaptation. The study sheds light on the evolutionary mechanisms behind bone mechanoadaptation and its relation to locomotion patterns such as bipedalism.
Research led by the University of Washington found that climate transitions over 56 million years ago fueled the emergence of diverse carnivoran body shapes. The Eocene-Oligocene Transition led to changes between families, while the Mid-Miocene Climate Transition drove diversification within families.
A study by University of Washington researchers found that climate changes over 56 million years ago led to diversification of modern carnivores. The Eocene-Oligocene Transition and Mid-Miocene Climate Transition drove the emergence of new body shapes among species such as dogs, cats, bears, and seals.
Researchers investigated the role of PLAGL1 in postnatal condyle development and found that it regulates osteogenesis through the IGF2 pathway. The study reveals a critical driver of jaw bone formation, offering opportunities for therapeutic exploration and a deeper understanding of craniofacial biology.
Salterella, a tiny Cambrian creature, has been reclassified with cnidarians due to its unique shell structure and mineral composition. The research team suggests that Salterella's shell served a distinct purpose, possibly related to feeding or stability.
Dr. Shivani Sahni, a nutritional epidemiologist, has been awarded Fellow Status by the American Society for Bone and Mineral Research for her outstanding contributions to bone and mineral science. She directs the Nutrition Program at Hebrew SeniorLife's Hinda and Arthur Marcus Institute for Aging Research.
Researchers uncovered two myeloid cell populations driving immune dysregulation in polytrauma, highlighting a critical role of TIM cells in immune suppression. The study also identified key genes and communication patterns involved in polytrauma-induced immune responses, providing potential targets for therapeutic intervention.
Researchers uncover how RUNX2 regulates cranial base growth by controlling chondrocyte differentiation, proliferation, and organization. The study provides fundamental insights into the complex interplay between RUNX2 and FGFR3, shedding light on novel therapeutic targets for craniofacial defects.
Researchers found corticosteroid injections accelerated structural knee degeneration, while hyaluronic acid injections slowed down damage. The study challenges common clinical practice and suggests alternative pain management strategies for patients with osteoarthritis.
A new species of ancient tree frog, Litoria tylerantiqua, has been discovered in Australia, challenging previous estimates of when Australian and South American tree frogs separated. The fossil record indicates that the separation occurred approximately 22 million years ago, rather than 33 million years ago as previously thought.
Researchers mapped all cells and pathways involved in early skeletal development, shedding light on arthritis and skull growth conditions. The study identifies genetic mutations disrupting soft spots in the skull, potentially leading to congenital conditions.
New research reveals that hormone therapy can alter skeletal size and shape in transgender individuals who previously suppressed puberty. Transgender men treated with puberty blockers and hormone therapy have broader shoulders and a smaller pelvic inlet, while women have a larger pelvis after treatment from early puberty.
Long-term treatment with methylene blue (MB) and mitoquinone (MitoQ) did not alter age-related bone loss in mice. Antioxidant interventions are insufficient to inhibit skeletal aging, suggesting alternative approaches may be needed.
Researchers found that one in five adults reported difficulty walking a kilometre, and those with more limitations had significantly higher fracture risks. The study suggests asking about walking ability could help identify individuals needing further screening and prescribe interventions to prevent fractures.
African spiny mice have been found to produce bone plates similar to those of armadillos, a discovery that challenges previous understanding of mammalian armor. The plates, known as osteoderms, provide protection and are distinct from scales found in other animals.
Researchers at the Florida Museum of Natural History found that frog forelimbs are not just for jumping, but also for fighting and grasping mates during reproduction. The fused radius and ulna bones provide strength and weight reduction, while also increasing stress on the tendon connecting to the bone.
A new study found evidence that multituberculates, an extinct group of mammals, likely reproduced in a placental-like manner. This discovery questions the long-held idea that marsupials were less advanced than placentals in terms of reproductive strategy.
The article highlights the importance of addressing systemic racism in forensic sciences by engaging with descendant communities and institutions. Forensic researchers advocate for repatriation and interment of remains collected without consent, emphasizing the need for uncomfortable conversations and criticism on issues related to race.