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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

'True grit' erodes assumptions about evolution

A new study led by the University of Washington found that certain South American mammals evolved long, strong teeth in response to the gritty dust and volcanic ash they encountered while feeding in an ancient tropical forest. The discovery contradicts the 140-year-old assumption about the evolution of specialized teeth.

Sony Alpha a7 IV (Body Only)

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Gains made towards treatment of rare bone disease

Scientists at McGill University and the Federal University of Sao Paulo have identified osteopontin as a key player in X-linked hypophosphatemia (XLH), a rare bone disease characterized by soft bones and tooth abnormalities. This discovery may lead to the development of an enzyme-replacement therapy to treat XLH patients.

Using mouthrinse reduces plaque and gingivitis more than toothbrushing alone

A six-month study published in General Dentistry found that using a germ-killing mouthrinse twice daily significantly reduced plaque and gingivitis compared to brushing alone. The study involved 139 adults with mild to moderate plaque and gingivitis, showing a 26.3% reduction in plaque and a 20.4% reduction in gingivitis.

Is there a Neanderthal in the house?

Researchers examine how our evolutionary history contributes to current health problems, such as obesity and childbirth complications. They suggest that understanding our past can help us better address these issues with alternative solutions like doula support during birth.

SAMSUNG T9 Portable SSD 2TB

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Beta-catenin molecule is required for tooth root formation

Research published in the Journal of Dental Research shows that beta-catenin is crucial for odontoblast cell differentiation and root development. Tissue-specific inactivation of beta-catenin in developing odontoblasts resulted in molars lacking roots and thin incisors.

Particles of crystalline quartz wear away teeth

The study found that quartz particles can remove pieces of tooth enamel at extremely low forces, making them a significant contributor to dental microwear. In contrast, fossilized plant remains had a minor effect on tooth surfaces, leaving only cosmetic rubbing marks.

Nature-inspired advance for treating sensitive teeth

Researchers have developed a new substance inspired by mussels' adhesive, which can rebuild both enamel and dentin on teeth. Laboratory tests show that the gooey material promotes simultaneous remineralization of enamel and dentin, offering a potential solution for millions suffering from tooth sensitivity.

Evidence contradicts idea that starvation caused saber-tooth cat extinction

A recent study using dental microwear texture analysis found no evidence of increased starvation in saber-tooth cats before their extinction. Instead, the research suggests that these great cats and American lions were well-fed and actively hunted prey, challenging popular theories on megafaunal extinction.

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The evolutionary origins of our pretty smile

Researchers used non-invasive X-ray technology to study the jaws and teeth of a primitive jawed fish called Compagopiscis. The discovery provides solid evidence that teeth evolved along with or soon after the development of jaws in early vertebrates, shedding light on our evolutionary ancestry.

Chewing ability linked to reduced dementia risk

Research from Karolinska Institutet found a significant association between difficulty chewing hard food and cognitive impairment, including dementia. The study of 557 people aged 77 or older suggests that maintaining good chewing ability may be crucial for brain health.

Ancient tooth may provide evidence of early human dentistry

A 6,500-year-old human jaw bone with a tooth showing traces of beeswax filling has been discovered, offering evidence of ancient dentistry in Europe. The beeswax was likely applied to reduce pain and sensitivity from a vertical crack in the tooth.

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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Coconut oil could combat tooth decay

Researchers found that enzyme-modified coconut oil strongly inhibited the growth of Streptococcus bacteria, a major cause of tooth decay. The study suggests that incorporating this natural compound into dental hygiene products could be a promising approach to combating microbial infection.

Gum disease 4 times as common in rheumatoid arthritis patients

A study found that rheumatoid arthritis patients are four times more likely to develop gum disease, with severe cases associated with increased inflammatory markers and antibodies. Gum disease in these patients may contribute to the development and maintenance of systemic inflammation.

Dental plaque may increase risk of premature cancer death

A Swedish study found that dental plaque is associated with a significantly increased risk of premature death from cancer. The research tracked the health of almost 1,400 adults for 24 years and found that those with high levels of plaque had a 79% higher risk of dying early from cancer.

Doing the tooth implant 2-step

A study published in the Journal of Clinical Periodontology concludes that a two-step tooth implantation method is more effective than a one-step process. The research found that implants placed using the two-step procedure show less wear and tear over time, with greater bone stability.

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The cutting edge

Using guillotine-based experiments and computer modeling, researchers at the University of Bristol studied the efficiency of bladed tooth shapes. They found that different shaped teeth are optimized for different types of food, with V-shaped edges being similar to those found in sharks and carnivorous mammals.

T. Rex's killer smile revealed

A University of Alberta paleontologist has discovered that Tyrannosaurus rex had the greatest variation in tooth morphology or structure among all tyrannosaurids. The varying edges enabled strong teeth to cut through flesh and bone, while the placement and angle directed food into its mouth.

Davis Instruments Vantage Pro2 Weather Station

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Professional dental cleanings may reduce risk of heart attack, stroke

A study by the American Heart Association found that frequent professional tooth scaling can lower the risk of heart attacks and strokes. Participants who received regular cleanings had a 24% lower risk of heart attack and 13% lower risk of stroke compared to those who never received dental care.

Homo sapiens arrived earlier in Europe than previously known

Researchers have re-analyzed ancient deciduous teeth from Grotta del Cavallo, Italy, and found they belong to anatomically modern humans. The new study suggests that Homo sapiens arrived in Europe earlier than previously known, with dates ranging from ~43,000-45,000 cal BP.

Filling without drilling

Researchers at the University of Leeds have developed a peptide-based fluid that reverses tooth decay by stimulating regeneration of damaged tooth tissue. The treatment is applied directly to the affected area, providing a natural and non-invasive solution to filling teeth without drilling.

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Early hominin landscape use

Researchers found that females preferred to disperse from their natal groups, similar to chimpanzees and human groups. The study suggests early hominins' social structure was not like that of gorillas.

AmScope B120C-5M Compound Microscope

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Periodontal stem cell transplantation shows promise

Researchers found periodontal ligament stem cells to be the most efficacious in treating advanced gum disease, outperforming other dental stem cell types. The study suggests PDLSCs may offer a new treatment option for periodontitis, a common cause of tooth loss worldwide.

Bone-creating protein could improve dental implant success

Researchers have found a bone-creating protein that can improve dental implant success when used to augment the maxillary sinus. The protein, BMP, induces superior bone quality and improves chances for successful implants compared to conventional bone grafting.

Aranet4 Home CO2 Monitor

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Ancient teeth raise new questions about the origins of modern man

Researchers uncover eight ancient teeth in Israel that are similar to those of modern humans, sparking new questions about the origins of Homo sapiens. The discovery, part of a larger excavation at the Qesem cave site, provides valuable insights into early human evolution and migration patterns.

Fighting the fight for healthy teeth

New research reveals that odontoblast cells in teeth orchestrate an immune response to protect against bacteria-induced decay. The cells produce proteins that down-regulate inflammation, protecting the underlying pulp from damage.

Preventing tooth decay in the youngest American Indians

Researchers found a significant decrease in tooth decay among young American Indians who switched from sweetened soda to water, with up to 63% reduction in early stage cavities. The study suggests that promoting water as a primary drink can have a substantial impact on preventing tooth decay.

Cracking a tooth

Scientists use atom-probe tomography to map millions of individual atoms in a sea creature's tooth, revealing organic/inorganic interfaces. This breakthrough opens up possibilities for tracking fluoride in teeth and cancer, osteoporosis drugs in bone, and designing new materials with improved properties.

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Was Israel the birthplace of modern man?

Archaeologists have found evidence of Homo sapiens in the Qesem Cave in Israel dating back to 400,000 years ago. The discovery challenges the long-held theory that modern man emerged from Africa 200,000 years ago and may indicate significant evolutionary changes in human behavior during this period.

Ever-sharp urchin teeth may yield tools that never need honing

Researchers have discovered the secret behind sea urchin teeth's ever-sharp quality, which could be mimicked to create self-sharpening tools. The unique biomineral mosaic structure of the teeth allows them to maintain sharpness despite constant grinding and scraping.

When their tools get dull, leaf-cutters switch jobs

Researchers found that leaf-cutter ants change tasks when mandibles wear out, allowing more efficient sisters to take over. This division of labor allows the colony to remain productive while minimizing energy loss.

For your teeth, Thanksgiving dinner is a real food fight

Researchers found that compounds in cranberry disrupt enzymes used by bacteria to form plaque, reducing acid production and cavities. Additionally, polyphenols from red wine waste inhibit S. mutans' activity and reduce acid production.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Cone of poison: The secret behind the cone snail's venom pump

Researchers have discovered how cone snails inject their venom after shooting a harpoon-like tooth into their prey. The venom is produced in the venom duct and pumped through by rapid contractions of the venom bulb, which also contains specialized muscles.

Technique to reattach teeth using stem cells developed at UIC

Researchers at UIC's Brodie Laboratory have successfully developed a technique to reattach teeth using stem cells, which could lead to a major advance in the battle against gum disease. The new strategy involves using periodontal ligament stem cells to form new fibrous attachments between the tooth and bone.

Taste genes predict tooth decay

A recent study published in the Journal of Dental Research has identified genetic variations in taste pathway genes as predictors of tooth decay. The researchers found associations between TAS2R38 and TAS1R2 genes and caries risk or protection.

Asthma and cavities both common in kids but not linked

According to a study published in JADA, asthma and cavities are both prevalent childhood diseases in the US. However, researchers found little evidence suggesting that asthma causes tooth decay, with some studies showing children with asthma having fewer cavities.

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A chip off the early hominin tooth

A new method, developed by Prof. Herzl Chai at Tel Aviv University, measures the size of chips in tooth fossils to determine the types of foods early humans consumed. The study found that larger chips indicate harder foods like nuts and seeds.

A smart use for wisdom teeth: Making stem cells

A new study reveals that mesenchymal stromal cells from wisdom teeth can be reprogrammed into stem cells, offering a potential source of treatment for patients. The cells displayed varying degrees of robustness and proliferated up to 100 times more efficiently than typical skin-cell-derived iPS cells.

What can a New Zealand reptile tell us about false teeth?

Researchers have used a tuatara's 3D computer model to understand how its jaw joints and muscles work together to prevent tooth damage. The study suggests that humans could benefit from a similar feedback system to reduce the risk of dental implant failures.

Chew on this: 6 dental myths debunked

A review article debunks common dental myths, highlighting the importance of a balanced diet in preventing tooth decay, osteoporosis, and gum disease. Carole Palmer, a professor at Tufts University School of Dental Medicine, outlines how nutrition affects oral health in children, teenagers, expectant mothers, adults, and elders.

Rigol DP832 Triple-Output Bench Power Supply

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Nano-sized advance toward next big treatment era in dentistry

Scientists have developed a multilayered, nano-sized film containing alpha melanocyte stimulating hormone to regenerate dental pulp, potentially revitalizing damaged teeth and reducing the need for root canal procedures. The film has anti-inflammatory properties and increased the number of fibroblasts in dental pulp.

The teeth of cadavers reveal their identity

A study published in Forensic Science International reveals that a person's dental patterns can be used as proof of their identity with the same degree of reliability as DNA testing. The researchers analyzed over 3,000 people and found variability values comparable to mitochondrial DNA.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Leaded gasoline predominant source of lead exposure in latter 20th century

A new study by Case Western Reserve University researchers found that leaded gasoline was the predominant source of lead exposure for African-American children in Cleveland during the latter half of the 20th century. The study used dental records and other data to show that lead levels in teeth increased dramatically during this period...