Articles tagged with Tendons
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Assistant Professor Karin Gravare Silbernagel will investigate differences in recovery between males and females with Achilles tendinopathy, exploring individualized treatment approaches to improve outcomes. Her research aims to better understand the variabilities in tendon injuries and develop more efficient treatments.
Researchers Nelly Andarawis-Puri and Johnny Huard received Kappa Delta Awards for their work on tendon healing and remodeling, and the use of adult stem cells in musculoskeletal tissue repair. Their research has led to a better understanding of how tendons heal and how to develop more effective treatments for musculoskeletal injuries.
Researchers analyzed gene expression changes in tendon tissue of male and female subjects aged 20-24 and 54-70. The study found opposite effects on genes expressed in males and females with age, highlighting the importance of considering gender differences in treating tendon disease.
Studies found that female athletes in track and field experienced more bone stress injuries and tendon abnormalities than other Olympic events. Researchers recommend early MRI imaging for early detection of bone stress reactions and pre-competition screening data for chronic lesion detection.
A new study from Linköping University finds that corticosteroids can improve tendon healing if administered at the correct timing. The research reveals that inflammation must subside before new tissue formation begins. When given after the early inflammatory phase, corticosteroids significantly enhance tendon strength in rats.
A study published in The FASEB Journal suggests that resistance training can prevent age-related tendon problems, such as ruptures and tendinopathies. The study found that trained rats showed fewer signs of age-related damage than sedentary rats.
Researchers are developing artificial muscle and tendon structures for more comfortable and efficient prosthetics, mimicking human muscles. The project aims to create dexterous, compliant, and affordable prostheses using smart materials with built-in actuation and sensing capabilities.
A new study has investigated the use of one-needle versus two-needle procedures for ultrasound-guided irrigation in treating rotator cuff calcific tendinopathy. The results showed that using two needles was more efficient for hard calcifications, while one needle was sufficient for fluid calcifications.
Researchers found that stem cells can produce anti-inflammatory cytokines, leading to improved tendon healing and matrix remodeling. The study suggests a new approach to treating tendon injuries and diseases by regulating inflammation.
Researchers from UConn Health have developed a way to regenerate rotator cuff tendons after they're torn, creating stronger repairs. The nano-textured fabric seeded with stem cells helps the tendons attach better to the bone and heal more evenly.
Scientists discover a tissue layer with extremely thin protein fibers at the interface between tendons and bones, explaining why athletes can withstand tremendous loads without damaging the bond. This breakthrough could lead to innovative connections in material research and tumour surgery.
UC Riverside-led research quantifies rattlesnake strikes for the first time using portable high-speed cameras, capturing three-dimensional video of a snake preying on a kangaroo rat. The study reveals that snakes can greatly exceed lab observations and that kangaroo rats may use elastic energy storage to evade strikes.
A new review found functional rehabilitation and minimally invasive surgery to be effective treatment options for Achilles tendon tears, especially in recreational athletes. Surgical repair may be optimal for high-performance athletes, offering improved strength and power.
Researchers found rotator cuff tendon overuse leads to degeneration of the shoulder tendon and osteoarthritis-like changes to neighboring cartilage. The study may help clinicians determine optimal treatment for tendon overuse injuries, reducing further damage.
A pooled analysis of available data reveals that shock-absorbing insoles do not prevent injuries or stress fractures. In contrast, foot orthotics have been shown to reduce the risk of overall injury and certain types of leg and foot pain by up to 41%. However, the quality of the evidence varies, and further rigorous research is needed.
The researchers developed a new metric to measure vertical agility, which allowed them to rank animals by their jumping agility and identify the galago as an inspiration for design. Salto achieved 78% of the galago's vertical jumping agility, with a maximum jump height of roughly 1.008 meters.
Tendon transfer surgery can significantly improve hand and elbow function in quadriplegics, enabling patients to perform daily activities like dressing and bathing. However, the procedure remains underused due to lack of coordinated collaboration among specialists.
A new study from TSRI researchers reveals the role of a gene called Mkx in maintaining and strengthening tendons in animal models. The findings may bring doctors closer to using gene therapies to grow and repair tendons.
Researchers at the University of Missouri have developed a new minimally invasive tendon repair technique that supports knee movement sooner after surgery. The suture anchor technique, which requires a smaller incision and disrupts less tissue, showed better strength results in human cadaveric tendon specimens.
A new intelligent technology called iTraining provides real-time feedback on muscle/tendon stresses and strains, enabling personalized rehabilitation programs. The system has the potential to transform the practice of exercise prescription across various performance levels.
Researchers at Queen Mary University of London identified specific proteins that help tendons slide, which slows down as horses age, increasing the risk of injury. The study provides a new insight into tendon aging and could lead to the development of prevention measures for racing horses.
Researchers found a significant increase in blood vessel and pain receptor growth among patients with calcific tendinitis, leading to chronic inflammation and severe pain. The study suggests new ways to manage the associated pain and may provide insights into other tendon disorders and diseases.
Biomedical engineer Prof Helen Lu has received a $1.125M grant to develop a nanofiber-based device for tendon-to-bone integration in rotator cuff repair, aiming to improve healing outcomes and reduce re-tear rates.
Most Achilles tendon ruptures can be effectively treated with conservative methods, including rest and physical therapy, before considering surgery. For acute tears in young or active patients, surgical intervention may be necessary to prevent re-rupture and promote quicker recovery.
A pooled analysis of available evidence suggests that high levels of total cholesterol are associated with an increased risk of tendon abnormalities and pain. Chronic low-level inflammation, prompted by cholesterol build-up in immune cells, may be a key factor contributing to this link.
A study by Swiss researchers evaluated the therapeutic potential of human fetal progenitor tenocytes (hFPTs) for tendon regeneration. The research found that hFPTs can stimulate adult tenocytes and potentially accelerate healing, with the possibility of reducing scarring.
A study presented at EULAR 2015 found that ultrasound diagnosis of tenosynovitis was superior to clinical symptoms in predicting early RA. This procedure has the potential to improve clinical outcomes by identifying the need for treatment before symptom onset.
A study found that injecting stem cells during rotator cuff surgery improved healing and durability of tendons. After 10 years, 87% of patients who received stem cell injections had intact rotator cuffs, compared to 44% without treatment.
Researchers found no significant differences in Achilles tendon thickness changes between running grades, indicating no increased risk of injury when transitioning to downhill running. Gradual adaptation is key to minimizing risks.
Researchers at UC Davis have developed a method to toughen up engineered cartilage and keep natural tissues strong outside the body. By depriving native or engineered cartilage of oxygen and using an enzyme called lysyl oxidase, they found that cross-linking occurs, making the material stronger.
Differences in proteins present in young and old tendons have been identified by researchers at Queen Mary University of London. Accumulated damage over time is thought to contribute to reduced ability of tendon cells to repair damage effectively, leading to increased risk of tendon injury with aging.
Scientists analyzed horse tendons to understand aging mechanisms, revealing protein differences between young and old horses. They found that certain proteins alter with age, slowing healing processes. This research could lead to better treatment strategies for human tendon injuries.
A Case Western Reserve University engineer has devised a technique to reconstitute collagen into tough fibers and induce adult stem cells to grow into tendons, which could lead to regenerating bulk volume of the tendon. The technology may also be used to repair hernias or urinary incontinence.
Researchers found that mechanical tension is established shortly after muscle-tendon contact, providing positional information for sarcomere formation. Without tension, muscles fail to build regular myofibrils, resulting in chaotic protein distribution.
A team of researchers is working to improve the outcome of surgical repairs for large rotator cuff tears in older patients by studying the natural attachment of tendon to bone. They plan to use advanced imaging methods and mechanical testing to understand how the natural tendon-to-bone insertion works and what goes wrong in healing.
Researchers at Queen Mary University of London uncovered a critical mechanism in tendon function, revealing why older individuals are more prone to tendon injuries. The study found that fascicle helices are essential for tendon elasticity and that ageing alters this structure, increasing the risk of injury.
A study presented at the Radiological Society of North America annual meeting found that ultrasound-guided PRP therapy improves functionality by 80% and pain by 75% in athletes with Achilles and patellar tendinosis. The therapy also normalizes MRI signal intensity in 90% of patients.
Researchers are working on an injectable compound that can block enzymes that further break down the tendon, reducing injury severity or promoting healing. The therapy aims to treat tendon injuries at an early stage, potentially benefiting athletes and industrial workers.
Researchers at Michigan Medicine are conducting a clinical trial to determine the effectiveness of platelet-rich plasma (PRP) therapy on tennis elbow. The study compares PRP injections to other treatments, including physical therapy and dry needling, in a blind study to minimize bias.
A new suture technique is designed to support tissue-engineered collagen grafts in tendon repair, distributing tension away from the injured tendon. The technique allows for weight-bearing as healing progresses, improving outcomes for tendon injuries.
A team of paleontologists discovered a new evolutionary mechanism for body elongation in early ray-finned fishes, characterized by the doubling of vertebral arches. The exceptionally preserved form, Saurichthys curionii, had a unique two-vertebral arch per myomeric segment, resulting in an overall elongate appearance and flexibility.
New UEA research reveals that moderate exercise may slow the progression of tendon disease by decreasing enzymes that degrade tendon tissue. The study showed a positive effect on tendons, suggesting a potential therapeutic approach to managing this debilitating condition.
Researchers discovered that fruitbats can store energy in their triceps tendons, enabling a power boost during take-off and flight. This unique ability allows bats to control joint movement with precision.
Researchers discovered that Achilles tendons retain high levels of carbon-14 from the Cold War era, indicating limited renewal and a slow healing process. This finding explains why tendon injuries often persist for years, but also opens up opportunities for developing new treatments to provoke dormant cells into repairing the tendon.
Researchers found that the Achilles tendon remains unchanged despite repeated high-impact loading. Human tissue samples from individuals exposed to nuclear bomb tests showed persistent radiocarbon levels decades after the event.
Researchers investigated the use of stem cells in treating equine tendon injuries. Bone marrow-derived mesenchymal stem cells and adipose-derived stem cells showed promise in strengthening tendons after injury, while umbilical cord blood-derived stem cells may offer even greater potential for tendon regeneration.
Researchers at Hospital for Special Surgery are studying the use of platelet-rich plasma (PRP) and stem cells to treat tendon injury and degeneration. The goal is to develop an effective therapeutic strategy to improve healing and reduce complications in NFL players.
A new study finds that immobilizing patients for longer periods after rotator cuff surgery may improve healing rates. The research used a rat model and found that immobilization improved tendon healing, reducing scar tissue and inflammation.
Researchers have identified the interfascicular matrix (IFM) as essential for tendon function, suggesting it may be critical in preventing tendon overuse injuries. The finding has significant implications for understanding and treating tendon disorders that cost the UK economy billions of pounds annually.
A team at University of East Anglia has identified changes in tendon structure and proteolytic enzyme activity as the cause of adult-acquired flat foot. The findings could lead to new drug therapies for this condition and others like Achilles tendonitis.
A sports medicine expert warns NBA players about the potential for serious injuries, particularly Achilles tendon injuries, due to prolonged lockouts. The expert cites a study from the NFL, which found a significant increase in career-threatening injuries after training camps began with minimal preparation.
Researchers at Brown University discovered that frogs' stretchy tendons are the key to their impressive jumping abilities. The study shows how the leg muscle shortens and loads energy into the tendon before releasing it to propel the frog forward, enabling them to jump much farther than expected.
Tufts University researcher Catherine Kuo is developing living tissue in the lab to study factors contributing to birth defects. She plans to engineer normal and abnormal tissues to investigate the impact of muscle movement on embryonic development.
Researchers at Brown University discovered that tendons absorb shocks and store energy, while muscles take on the role of absorbing remaining energy after impact. This finding highlights the critical role of tendons in shock absorption and has implications for the development of synthetic tendons and rehabilitative practices.
Researchers found that curcumin can suppress inflammation in tendon diseases, potentially reducing reliance on NSAIDs. This natural compound could be used to treat tendinitis and other inflammatory conditions.
Researchers identified patients with high femoral anteversion who experience poor surgical outcomes for snapping psoas tendon treatment. This study suggests that releasing the psoas tendon in these patients may result in delayed return to activities and inferior outcomes.
Researchers found a thin layer of epithelial cells on healthy tendons that prevent adhesion formation. Mice with defective cells developed tendon adhesions, highlighting the importance of tissue surface integrity.
Researchers at Washington University in St. Louis have developed a biomimetic patch to improve the success rate of rotator cuff repairs. The patch, which mimics the natural tissue, is designed to guide the healing process along the path it follows during development.
A recent study by the American Orthopaedic Society for Sports Medicine found that platelet-rich plasma (PRP) therapy does not significantly improve healing after a rotator cuff tendon repair. Researchers observed no notable differences in tendon-to-bone healing rates between patients who received PRP and those who did not.
A recent study by Hospital for Special Surgery investigators found no improvement in tendon healing after rotator cuff repair using platelet-rich fibrin matrix. The study's findings question the premature use of PRP in some cases, highlighting the need for further research on dosing and timing.