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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Learning impacts how the brain processes what we see

Researchers found that learning enhances top-down control in the brain's visual cortex, allowing it to better predict and fill in missing information. This cognitive process has implications for understanding psychiatric diseases such as schizophrenia.

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Fine tuning in the brain

Researchers developed a computer model to simulate the biological processes of neural network development in the visual cortex. The results show that newborns possess specialized nerve cells but lack systematic connections, which are refined through experience, leading to improved perception.

Functioning brain follows famous sand pile model

The brain's electrical activity displays statistical hallmarks of criticality, a state where information processing is optimized. Spontaneous avalanches in the brain hold it at this balance point, with sensory input momentarily pushing the cortex away but adapting back to optimal critical regime.

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How does the brain adapt to the restoration of eyesight?

Scientists studied a woman with low vision since birth whose vision was restored through surgery. While the brain's visual cortex showed some plasticity, full normal functioning was not regained after several months. The study has implications for predicting outcomes in individuals considering eye surgery.

In one aspect of vision, computers catch up to primate brain

Researchers found that newer generation of deep neural networks can identify visual objects as accurately as the primate brain. The success suggests neuroscientists have a fairly accurate grasp of how object recognition works, which could lead to better artificial intelligence and new ways to repair visual dysfunction.

Scientists use lasers to control mouse brain switchboard

A study found that just a few nerve cells in the thalamic reticular nucleus (TRN) may control the switch between internal thoughts and external distractions. The TRN's firing patterns were altered using laser light, revealing its role in regulating consciousness and mental states.

Oregon study details brain pathways linking visual function, running

Researchers at the University of Oregon have identified a brainstem circuit in mice that links visual processing with physical movement. The discovery suggests that active movement can enhance sensory perception, potentially leading to new treatments for motor dysfunction and neuroplasticity enhancement.

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How the brain pays attention

A new study reveals that the brain achieves focused attention on faces or other objects by synchronizing activity in the inferior frontal junction (IFJ) with specific brain regions. The IFJ coordinates with the fusiform face area (FFA) and parahippocampal place area (PPA), suggesting a parallel process involving different areas.

'Seeing' bodies with sound (no sight required)

Congenitally blind individuals can learn to recognize human body shapes through soundscapes, with an average of 70 hours of training required. The brain's visual cortex responds to sound patterns, allowing participants to detect posture and imitate movements.

Expanding our view of vision

Researchers have noninvasively mapped human brain activity with unique accuracy, identifying both location and timing of brain processes. The study used a novel brain-scanning technique combining fMRI and MEG data to pinpoint when the brain recognizes objects and categorizes them.

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Neurons subtract images and use the differences

Researchers discovered that the brain reduces data volumes in the primary visual cortex, using image differences to efficiently process sensory information. The study used novel optical imaging methods and found that neurons represent only new or missing elements when the time elapsing between images is longer than 100 milliseconds.

When neurons have less to say, they speak up

In a breakthrough study, researchers found that brain neurons can regulate their own activity to maintain a constant level of activity even after significant changes, such as sensory organ loss. This allows for regeneration and adaptation, essential for healthy brain function and recovery from injury.

New theory of synapse formation in the brain

Researchers have discovered a simple homeostatic rule that governs the formation of new neural networks in the visual cortex, enabling the brain to adapt to changes. The theory also sheds light on how synapses are formed and abandoned, with implications for understanding learning processes and treating neurological diseases.

Finding the place where the brain creates illusory shapes and surfaces

A team of neuroscientists has identified a specific area in the visual cortex called V4 that is involved in creating illusory contours. The brain's neural activity in this region correlates with the perception of these illusions, which are thought to be an evolutionary adaptation for detecting predators or prey.

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Imaging biomarker predicts response to rapid antidepressant

A study found that a biomarker based on brain activity in the visual cortex can predict response to scopolamine, an experimental rapid-acting antidepressant. Patients with depression showed lower visual cortex activity, which correlated with treatment response.

The eyes have it: Men do see things differently to women

Researchers found that men have a greater sensitivity to fine detail and rapidly moving stimuli, while women excel at distinguishing colors. This difference is attributed to the presence of more neurons in the visual cortex of males.

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Princeton study reveals the brain's mysterious switchboard operator

A mysterious region in the human brain, called the pulvinar, acts as a switchboard operator that sorts through external stimuli and focuses on relevant information. This discovery could lead to new ways of understanding and treating attention-related disorders like ADHD and schizophrenia.

Neural balls and strikes: Where categories live in the brain

Neural recordings reveal brain activity that encodes visual categories in the posterior parietal cortex, outperforming the prefrontal cortex. The study suggests that the parietal cortex is more involved in the categorization process, particularly for spatial and visual tasks.

Do you see what I see?

A team of researchers developed a computer model based on human neural structure and function to recognize shapes. The model, inspired by the hierarchical organization of the human visual cortex, successfully reproduced human performance in identifying shapes, opening up new ways to approach object detection problems.

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Brain study explores what makes colors and numbers collide

A recent study reveals that individuals with grapheme-color synesthesia exhibit increased activity in the brain's visual cortex, a finding that provides insight into the neural mechanisms underlying conscious awareness. The research also suggests that the brains of synesthetes may be more excitable than those without the condition.

Attention and awareness uncoupled

A recent study using functional magnetic resonance imaging has found that attention, rather than awareness, modulates the activity in the primary visual cortex. This suggests that these two mental processes may be dissociated and affect nerve cells differently. The findings have implications for philosophy and psychology.

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NeuroImage: Multiplexing in the visual brain

Researchers at Ruhr-University Bochum successfully visualized distinct activity patterns overlaid in primary visual cortex, indicating simultaneous encoding of object orientation and motion direction speed. This breakthrough demonstrates the brain's ability to process multiple visual cues simultaneously.

MIT-- parts of brain can switch functions

In people born blind, parts of the visual cortex are recruited for language processing, overturning the idea that language processing occurs in highly specialized brain regions. The study suggests that brain function is more dynamic and adaptable than previously thought.

Seeing the world differently

Researchers found that individual volunteers' perceptions of optical illusions varied greatly due to differences in brain size. The primary visual cortex area affects the extent to which we see visual illusions.

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Growing brain is particularly flexible

The brain is highly flexible during growth, with neuronal connections restructured through self-organisational processes. The number of nerve cells remains unchanged, but non-neuronal cells increase, enabling the visual cortex to adapt to new experiences.

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Seeing the brain hear reveals surprises about how sound is processed

Neurobiologists at the University of Maryland discovered that the brain's auditory cortex is more complex and chaotic than previously thought, with neighboring neurons creating different outputs. This disorder could indicate that the brain is far more adaptable than previously thought.

Yale team finds neural thermostat keeps brain running efficiently

A Yale team found that inhibitory neurons in the visual cortex control how excitatory cells interact, allowing the brain to process complex scenes efficiently. The 'iceberg phenomenon' shows that only essential information is processed, while non-essential stimuli are suppressed.

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Babies see it coming

A new study shows that infants as young as five months old have established neural pathways to sense looming danger. As they become more mobile, their ability to process this information improves, with more mature infants able to respond faster.

JHU researcher discovers brain cells have 'memory'

Researchers at Johns Hopkins University found that brain cells in a specific region store visual information for up to two seconds, enabling the creation of a stable visual world despite rapid changes. This discovery may have practical implications for understanding and treating disorders such as attention deficit disorder and dyslexia.

Rigorous visual training teaches the brain to see again after stroke

Researchers successfully trained patients with severe visual impairments after a stroke to regain some vision through intensive computer exercises. By building on existing 'blindsight,' the brain's healthy regions were stimulated to take on tasks normally handled by damaged areas.

What drives brain changes in macular degeneration?

A new MIT study sheds light on the underlying neural mechanism of macular degeneration, revealing that deprived neurons respond equally to stimuli at both preferred and non-preferred locations. The findings suggest a relatively passive response to visual deprivation.

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Study indicates how we maintain visual details in short-term memory

A study by John T. Serences and colleagues found that the visual cortex actively 'thinks' about specific features of an object during short-term memory, allowing for the maintenance of relevant details. This suggests that observers have top-down control over which features are stored in their online mental workspace.

Brain reorganizes to adjust for loss of vision

A new study shows that brain activity increases in the visual cortex when patients with macular degeneration focus on using other parts of their retina to compensate for their loss of central vision. The brain reorganizes its neural connections to process information from other parts of the eye.

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Scientists unmask brain's hidden potential

A long-term study found that sudden vision loss leads to rapid changes in the visual cortex, enabling it to process touch. The brain's adaptability was revealed to be greater than previously thought, with potential implications for other sensory losses and brain injuries.

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Sound adds speed to visual perception

A recent study in monkeys found that auditory stimulation directly improves visual perception without involving higher brain areas. The researchers recorded neuronal responses and measured latency, showing a 5-10% decrease in response time when visual signals were weaker, suggesting the auditory cue speeds up the response.

Antidepressants enhance neuronal plasticity in the visual system

The study found that antidepressants like fluoxetine enhance neuronal plasticity in the visual system by increasing brain-derived neurotrophic factor (BDNF), allowing for improved vision in individuals with amblyopia. Environmental stimuli, such as rehabilitation or therapy, are required to guide the rearrangement of cortical connections.