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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Plant physiology: Safeguarding chloroplasts from sunburn

Researchers have discovered a previously unknown signaling pathway that protects chloroplasts from damage caused by intense sunlight. This pathway, involving the protein SAFE1, suppresses light-induced programmed cell death and promotes stress tolerance in plants.

How to build a chloroplast

A team of researchers from Japan and the UK has identified a crucial communication route in developing chloroplasts, the energy factories of plant cells. The newly characterized protein GUN1 regulates tetrapyrrole biosynthesis, controlling the cell's production of heme.

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Protein that triggers plant defenses to light stress identified

Researchers have discovered a protein that triggers a defense mechanism in plant cells when exposed to excessive light, protecting them from damage. This finding has implications for agriculture, as it could help crops withstand harsh climate conditions and increase the production of proteins used in vaccines.

Mystery behind striped barley solved

Researchers have identified the HvAST gene as the cause of variegation in albostrians barley, a breakthrough that sheds new light on chloroplast biogenesis. The discovery provides novel insights into the molecular mechanisms underlying chloroplast development and has significant implications for plant biology.

It's not easy being green

UC Riverside researchers identified two genes responsible for regulating plant greening through mutant plant experiments. The discovery sheds light on the complex process of photosynthesis and its control by the cell's nucleus and chloroplasts.

Plants are also stressed out

Researchers discover GUN1 plays a crucial role in regulating chloroplast-to-nucleus communication, enabling plants to respond to stress. This finding may help breed plants that can better withstand environmental stressors and maintain food production.

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An easier way to engineer plants

A new genetic tool has been developed by MIT researchers, allowing for easier engineering of plants that can survive drought or resist fungal infections. The technique uses nanoparticles to deliver genes into the chloroplasts of plant cells, which have the potential to revolutionize plant biology and agriculture.

Growing the tallest is not always the best option

Researchers at CRAG have discovered that chloroplasts play a key role in regulating the shade avoidance syndrome in plants, allowing them to optimize photosynthesis. This discovery has important implications for improving crop productivity without increasing land use.

Scientists debunk potential link to crop cold tolerance

A new study by the University of Illinois and Massachusetts Institute of Technology refutes the idea that C4 crops like corn and sugarcane are limited in their ability to produce Rubisco, an enzyme essential for photosynthesis. The researchers found that these crops' chloroplasts have sufficient space to house more than enough Rubisco ...

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How chloroplasts maintain energy efficiency

Researchers found that mature plant chloroplasts isolate ATP production, while young leaves allow for temporary import of ATP to support development. This strategy optimizes energy efficiency in plants.

When the seed becomes a plant, it has 48 hours to survive

Researchers at Université de Genève reveal the mechanism of seed germination, where proplastids differentiate into chloroplasts within 48 hours. The process is controlled by growth hormone gibberellic acid and protein TOC159, ensuring rapid transition to autonomous growth.

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Summer fun: How plants beat the heat

A team of researchers at RIKEN Center for Sustainable Resource Science has discovered a gene in plants called Heat Inducible Lipase 1 (HIL1) that helps protect them from excessive heat. This gene enables plants to modify their fats, which stabilize chloroplast membranes and prevent damage from high temperatures.

Plants feel the heat

A team of researchers has discovered that plants' daily cycle of heat resistance is triggered by light exposure and involves chloroplast signalling. This finding could lead to the development of crops that can withstand increasingly hot temperatures and more frequent heatwaves under climate change.

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Tracing a plant's steps: Following seed dispersal using chloroplast DNA

Researchers developed a new tool to sequence chloroplast DNA from hundreds of plants at once, allowing for accurate tracking of seed dispersal across landscapes. This method has significantly reduced the costs of genetic studies, enabling biologists to investigate plant populations and their movements.

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The origin of the chloroplast

A new study reveals that the chloroplast lineage split from its closest cyanobacterial ancestor over 2.1 billion years ago in low salinity environments, marking a crucial step in photosynthesis evolution. The association of the chloroplast with its eukaryotic host took place around 800-750 million years ago in marine environments.

Hydrogen peroxide protects plants against sun damage

Researchers discovered that hydrogen peroxide plays a crucial role in plant adaptation to sunlight. Plants use H2O2 to signal genes in their cell nuclei, allowing them to adjust and protect photosynthesis. This process ensures plants continue to thrive under varying light conditions.

Disentangling chloroplast genetics

Japanese researchers isolated a protein essential for chloroplast nucleoid segregation, improving understanding of chloroplast DNA dynamics. The moc1 gene functions as a 'Holliday junction resolvase', untangling DNA structures crucial for cell health.

A mutation giving leaves with white spots has been identified

A new mutation in the Lotus japonicus plant has been identified, resulting in leaves with white spots. The mutation is linked to a shortage of chloroplast proteins, which are crucial for plant growth, and may hold clues for improving ornamental plants.

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Collapsed chloroplasts are targeted in self-eating process

Scientists at Tohoku University have discovered a previously unknown type of autophagy that removes damaged chloroplasts in plants, shedding light on the aging process. This finding could lead to new methods for controlling plant aging and enhancing crop yields.

Helpers for energy acquisition from plants

Scientists at Universität Bonn have discovered a lipid transfer process crucial for plant cell survival. This process enables the exchange of galactolipids between chloroplast membrane envelopes, facilitating photosynthesis and plant growth.

Novel 'repair system' discovered in algae may yield new tools for biotechnology

Researchers have discovered a novel repair system in algae that can cut out interrupting sequences from proteins, potentially leading to new biotechnological applications such as producing pharmaceuticals or protein products. The study found that chloroplast extracts and light can restore RNA-cutting activity to inactive proteins.

Hidden moss chloroplast 'wall' discovered

Researchers visualize peptidoglycan 'wall' in moss chloroplasts for the first time, overturning traditional understanding of chloroplast structure. The discovery has significant implications for our knowledge of plant cell biology and the origins of photosynthesis.

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A plant cell recycles its resources in times of scarcity

Researchers at Université de Genève identified a protein Mac1 that plays a key role in recycling photosystem I components to recover iron. In response to nutrient deficiencies, the alga dismantles its photosystems and recycles some of their components.

Seeing the big picture in photosynthetic light harvesting

The new model simulates light-harvesting across a thylakoid membrane, enabling the explanation of PSII's high quantum efficiency. The research paves the way for improving food crop yields and developing artificial photosynthesis technologies for solar energy systems.

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Cellular damage control system helps plants tough it out

Plants have developed a unique mechanism to selectively degrade damaged chloroplasts, allowing them to conserve energy and thrive in challenging environments. This discovery could lead to the development of stronger crops with improved yield and resistance to stressors.

Chloroplast tubes play a key role in plants' immune defense

Researchers at UC Davis and the University of Delaware discovered that chloroplast tubes play a key role in plants' immune defense. The discovery reveals how chloroplasts deliver signals to the nucleus, inducing programmed cell death and preparing other cells to resist infection.

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Fusion protein controls design of photosynthesis platform

Researchers at Johannes Gutenberg University Mainz identified IM30 as a protein that triggers membrane fusion, crucial for thylakoid membrane system formation and maintenance. This discovery provides a starting point for future research on membrane fusion mechanisms in chloroplasts and blue-green algae.

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A novel shuttle for fatty acids

Researchers at Ludwig Maximilians University have identified a novel chloroplast membrane protein that plays a central role in transporting fatty acids from chloroplasts into the cell cytoplasm. This discovery may lead to new strategies for producing biofuels, which are rich in TAG-rich plant oils.

How vitamin C helps plants beat the sun

Researchers from RIKEN and Okayama University identified PHT4;4 as the transport protein allowing vitamin C to enter chloroplasts. This discovery could lead to crop plants with higher tolerances to environmental stress, reducing damage to farmland in regions with strong light.

Bionic plants

Researchers embedded carbon nanotubes into chloroplasts to capture light energy by 30 percent. Plants were also modified to detect nitric oxide, a common environmental pollutant. This represents the first steps in launching plant nanobionics, a field that could turn plants into self-powered devices.

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New cell component important to tea and wine-making

Researchers at Oxford University Press UK identified the tannosome organelle, responsible for producing complex chemicals used in plant defense and protection. This discovery sheds light on the synthesis of tannins, a key component in making tea and red wine taste their distinctive way.

Clues in coral bleaching mystery

New research from Carnegie Institution for Science reveals that coral bleaching occurs even when algae are heat-stressed in the dark, suggesting novel mechanisms beyond toxic oxygen molecules. The study provides key details on the breakdown of photosynthetic apparatus and potential strategies to mitigate bleaching.

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Optimizing microbe factories

Researchers aim to improve biosynthetic yield of valuable natural products using metabolically modified bacteria with optimized MEP pathways. The goal is to produce high-quality substances efficiently, reducing labor and costs in the process.

Photosynthesis: Membranes in tight corners

A team of scientists identified a protein that induces membrane curvature in thylakoids, enabling the formation of stacks. The CURT1 protein enhances photosynthesis efficiency by increasing the degree of stacking and potentially boosting crop yields.

Fishing in the sea of proteins

For the first time, a large complex of proteins and RNA has been identified in chloroplasts, which cuts non-coding regions out of messenger RNA to create a protein blueprint. The study reveals that this splicing complex contains 23 different proteins encoded in the cell nucleus.

Scientists date prehistoric bacterial invasion still present in today's cells

Researchers date cyanobacterial invasion into one-celled plants to 900 million years ago, revealing new insights into the origins of photosynthesis. By analyzing fossil and genetic evidence, they estimated the age of this ancient event, providing a more precise timeline for the evolution of plant and animal cells.

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Sequencing hundreds of chloroplast genomes now possible

Plant biologists can now sequence hundreds of complete chloroplast genomes simultaneously, facilitating studies on molecular biology and evolution. This breakthrough allows researchers to reconstruct evolutionary relationships and diversifications with unprecedented precision.