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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

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Jumping gene enabled key step in corn domestication

Scientists have pinpointed a key genetic change that enabled the domestication of corn from its wild relative teosinte. A jumping gene insertion about 23,000 years ago increased the expression of a gene affecting plant architecture, leading to larger ears with more kernels.

Miscanthus adapts

A study on Miscanthus species reveals their potential as high-yield energy crops capable of growing on marginal land. The authors found that wild populations have genetic variation and adaptation that could provide valuable resources for the development of bioenergy crops.

Cactus genes connect modern Mexico to its prehistoric past

A team led by Fabiola Parra has successfully traced the domesticated Gray Ghost Organ Pipe (Stenocereus pruinosus) to its living ancestral species in Mexico's Tehuacán Valley. Genetic analysis reveals evidence of artificial selection, increasing genetic diversity among cacti grown using traditional methods.

What plant genes tell us about crop domestication

A QTL mapping study reveals that only modest genetic modifications are needed to convert a wild plant to a crop, with some major transitions achievable by a single change. The genetic evidence supports the archeological view of gradual and dispersed domestication.

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The amazing maze of maize evolution

Dr. Marina Dermastia and colleagues discovered similarities between maize and teosinte kernel development, overturning previous assumptions about domestication. The team found traits like programmed cell death, sugar flow control, and endoreduplication that are common to both crops, suggesting they evolved independently.

New research reveals the earliest evidence for corn in the New World

A team of scientists led by Dolores Piperno has discovered the earliest evidence of maize domestication in the New World, dating back to 8,700 years ago. The research confirms that maize originated from a wild plant called teosinte and was first domesticated in tropical southwest Mexico.

Wild grass became maize crop more than 8,700 years ago

Researchers found evidence of maize and squash domestication in the Xihuatoxtla Shelter in southwestern Mexico, dating back 9,000 years. The findings contradict previous assumptions that maize domestication occurred in highland areas.

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Researchers find the earliest evidence of domesticated maize

Researchers discovered the earliest dated evidence of domesticated maize, dating back over 8,700 years to Mexico's Central Balsas River Valley. The team found maize starch and phytoliths in grinding tools and lake sediments, confirming that maize was derived from teosinte.

Research pushes back history of crop development 10,000 years

A new mathematical model developed by researchers at the University of Warwick suggests that plant agriculture began much earlier than previously thought, around 23,000 years ago. The study found that useful gene types took thousands of years to become stable and that crop development was a slow process.

Early origins of maize in Mexico

A team of scientists has used paleobotanical evidence, genetic analysis, and microbotanical techniques to reconstruct the early history of maize agriculture. They suggest that maize may have been domesticated in Mexico around 10,000 years ago, based on findings from sediments at San Andrés, Tabasco.

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Ancient sunflower fuels debate about agriculture in the Americas

Researchers confirm ancient sunflower domestication in Mexico dating back 4,000 years, contrary to previously believed eastern North American origin. This discovery highlights the importance of sunflower as a major oil seed crop and its potential for modern crop-breeding purposes.

Sunflower debate ends in Mexico, researchers say

Researchers confirm that farmers domesticated sunflowers in Mexico by 2600 B.C., contradicting the theory that they were introduced from eastern North America. The study's findings are based on physical evidence of early domesticated remains and linguistic traditions.

Practice of farming reaches back farther than thought

Ancient people in Panama processed domesticated plants like maize, manioc, and arrowroot at least 7,800 years ago, revealing an earlier practice of farming than previously thought. This discovery confirms the importance of starch grain analysis as a method for studying human subsistence practices in tropical forests.

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Biologists find regions of rice domestication

Researchers found genetic markers revealing the origins of two major rice types grown today: Oryza sativa indica from India and Myanmar, and Oryza sativa japonica from southern China. The study's findings provide insights into improving the crop's nutritional value and disease resistance in Asia.

MSU researchers shake out basis for rice domestication

Researchers pinpointed a single base pair mutation in DNA that causes non-shattering rice varieties, allowing for effective field harvests. This discovery will benefit the world by improving yields and sustainability of food crops, particularly rice, which is staple food for over half of the global population.

Central Americans save plant diversity through local cultivations

Researchers at Washington University in St. Louis report that Central American farmers have preserved genetic variation in the jocote by growing it locally for family consumption. This practice, despite large-scale deforestation, has helped maintain diversity in the species through multiple domestications.

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The genetic origins of corn on the cob

Researchers at Cold Spring Harbor Laboratory have isolated the ramosa1 gene, which controls flower-bearing branch arrangement in corn. This gene played a key role in suppressing branching in early domesticated corn, leading to straight rows of kernels and compact ears. The study also reveals that plants with different levels of ramosa1...

Domesticated tree crops may be the 'future of forestry'

Researchers at Purdue University have developed a method to identify genes in tree species, paving the way for domesticated trees. This breakthrough aims to reduce the need for logging wilderness areas by producing ideal characteristics such as insect resistance or improved wood properties.

An origin of new world agriculture in coastal Ecuador

Researchers at the Smithsonian Tropical Research Institute have discovered evidence of early domestication of wild squash varieties in coastal Ecuador dating back to around 12,000 years ago. The phytoliths found in these ancient fruits suggest a significant shift towards more productive agricultural practices among hunter-gatherers.

Wild plant or food plant?

Researchers have identified a single genetic locus in the squash genus Cucurbita that controls phytolith production and plant defense. This discovery will help archaeologists determine whether ancient plants were domesticated or wild varieties by analyzing their phytolith content and cell configurations.

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Genetic marker tells squash domestication story

Scientists have identified a genetic marker that points to Mexico as the origin of domesticated squash, contradicting previous theories. The study used mitochondrial DNA genetic markers to analyze the relationships between wild and domesticated Cucurbita pepo populations.

Taming wild wheat

Researchers at Cold Spring Harbor Laboratory have created a 'map' of the wild emmer wheat genome, revealing hundreds of unique DNA sequences on 14 chromosomes. This new understanding will aid in breeding better wheat crops and shed light on the evolution of wheat.

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Where the wild ones are: origins of staple crop found

Biologists at Washington University pinpointed cassava's origins to southern border of the Amazon River basin in Brazil using DNA sequencing techniques. The study reveals genetic diversity in wild and domesticated cassava strains, providing insights into crop improvement.