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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

How size matters

Researchers at Norwich BioScience Institutes discover that cells at the margins of leaves and petals secrete a mobile growth signal controlling size. This signal is distinct from classical plant hormones, influencing leaf division until a certain threshold is reached.

Endosome-mediated signaling in plants

Researchers found endosomes facilitate plant growth through brassinosteroid receptor trafficking, affecting shoot and root growth. This discovery expands understanding of endosome function in plants, shedding light on their evolutionary origins.

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Research identifies protein that signals flowering in squash plants

Researchers have identified the FT protein as a key player in signaling flowering in squash plants, using an obligate short-day plant system. The study provides strong evidence that FT protein acts as a florigenic signal, and its presence in the phloem sap of flowering plants supports this conclusion.

Plants tag insect herbivores with an alarm

Researchers have identified a specific class of small peptide elicitors that help plants react to insect attack, triggering defensive chemistry and improving protection against pests. The discovery opens the door for genetic manipulation of plants with improved defense mechanisms.

Scientists unlock secret of what makes plants flower

Researchers at Imperial College London discovered that a protein called Flowering Locus T Protein (FT) plays a crucial role in plant flowering. The FT protein travels from leaves to the shoot apex, triggering the production of genes that cause flowers to bloom.

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'NO' allergic reaction linked to hayfever

Research suggests that nitric oxide and nitrite released by pollen grains trigger allergic responses in the nose. The study, funded by the Wellcome Trust, aims to investigate the role of these compounds in human cell inflammation during hayfever.

All roads lead to GUN1

Researchers at the Salk Institute discovered that GUN1, a nuclear-encoded protein, plays a crucial role in transmitting distress signals from damaged chloroplasts to the nucleus, triggering a shutdown of photosynthetic genes. This finding sheds light on the complex communication between organelles and the nucleus.

Satellite radar gauges water levels in Louisiana wetlands

Researchers at Ohio State University developed a satellite radar technique to measure water levels in vegetated wetlands. The study found rising and dropping water levels in selected sites over a decade, including changes caused by seasonal rainfall.

Salk scientists untangle steroid hormone signaling in plants

Researchers at the Salk Institute have clarified the response pathway to steroid hormone brassinolide, a key element in plant growth. The study reveals that BES1 is activated in the nucleus after BIN2 inhibition, leading to gene activation and promoting plant growth.

Plants respond similarly to signals from friends, enemies

Researchers at North Carolina State University discovered that plants respond similarly to signals from both beneficial rhizobia and parasitic root-knot nematodes. This response involves rapid changes in the distribution of the plant's cytoskeleton, leading to growth changes such as nodules or galls.

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Below the surface: New clues to plant signaling from the roots

Researchers at the University of Utah have identified a novel gene, BYPASS1, that regulates root-to-shoot communication and controls plant architecture. The study reveals that roots produce a growth-inhibiting substance that affects shoot development, providing new insights into plant signaling.

Coping: Plant adaptability to stress discovered

Researchers have identified a system in a mutant arabidopsis that signals cells to pause during stressful situations, allowing plants to regulate themselves and adjust before growth resumes. This discovery may lead to breeding plants with improved stress handling techniques and enhanced drought tolerance.

Researchers identify key molecular signal in plant pollination

Researchers have identified gamma-amino butyric acid (GABA) as a key signaling molecule that triggers plant reproduction and guides the growth of pollen tubes. In contrast, mutants with deficient GABA degradation produce a massive increase in the chemical signal, overwhelming the pollen tubes and disrupting their guidance.

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