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Rice scientists synthesize anti-cancer agent

Researchers at Rice University have developed a new method for synthesizing the potent anti-cancer agent trioxacarcin, which damages DNA and disrupts cancer cell replication. This breakthrough allows for more efficient production of these valuable molecules, enabling their study as potential new medications.

'Big data' drills down into metabolic details

A new computational method, CORDA, models tissue-specific metabolic pathways by assigning a cost to reactions without experimental data. Researchers found key differences in metabolic similarities between healthy and cancerous tissues, including up-regulation of folate metabolism.

SourceRice University·JournalPLOS Computational Biology·DateMar 9, 2016

Study: Cancer cells eat their neighbors' 'words'

Researchers at Rice University discovered that cancer cells can consume amino acids directly from exosomes, tiny packets of proteins and nucleic acids, to fuel tumor growth. This finding contradicts the long-held Warburg effect theory, suggesting each type of cancer has a unique metabolic profile.

Cancer cells' evasive action revealed

Researchers have discovered a trick used by lung cancer cells to hide from the immune system, specifically suppressing immunoproteasomes that signal T-cells to attack diseased cells. The study suggests it may be possible to enhance production of these proteins to override the cells' escape mechanism.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateMar 2, 2016

New theorem helps reveal tuberculosis' secret

A new methodology developed at Rice and Rutgers universities helps scientists understand how biochemical networks control biological responses. The approach predicted novel interactions in bacteria that cause tuberculosis, revealing a potential mechanism for the disease's survival.

SourceRice University·JournalPLOS Computational Biology·DateFeb 22, 2016

Marine virus outbreaks linked to coral bleaching

A study by Rice University and Oregon State University found that significant marine virus outbreaks may be associated with coral bleaching events, especially due to multiple environmental stresses. Viral groups, including a herpes-like virus, were detected in corals undergoing bleaching on the Great Barrier Reef.

SourceRice University·JournalFrontiers in Microbiology·DateFeb 17, 2016

Proto-planet has 2 masters

New Atacama Large Millimeter/submillimeter Array (ALMA) images provide detail on the binary star system HD 142527, revealing a broad ring of dust and ice. The system's formation is expected to yield insights into planetary systems around binary stars.

Too-few proteins prompt nanoparticles to clump

Rice scientists observed that blood serum proteins irreversibly attach, unfold, and bring gold nanoparticles together in low concentrations. This counterintuitive behavior has significant implications for diseases caused by aggregation, such as Alzheimer's, and nanoparticle toxicity issues.

SourceRice University·JournalACS Nano·DateJan 28, 2016

Heavy fermions get nuclear boost on way to superconductivity

Physicists have discovered that nuclear effects help bring about superconductivity in YRS, a composite material of ytterbium and rare earth elements. This finding provides further evidence that unconventional superconductivity arises from quantum criticality and exposes the role of nuclear spins in exposing electronic quantum criticality.

SourceRice University·JournalScience·DateJan 28, 2016

Nano-coating makes coaxial cables lighter

Researchers create flexible, high-performance coating that replaces metal braid with carbon nanotubes, benefiting airplanes and spacecraft. The new cable reduces weight by 97%, meeting military-grade standards for shielding and strength.

SourceRice University·JournalACS Applied Materials & Interfaces·DateJan 27, 2016

Feds back new heart patch for infants

Researchers at Rice University have won a National Institutes of Health grant to develop new patches that encourage the growth of the child's own heart tissue. The new patches are designed to blend in with the surrounding tissue, reducing the risk of rejection and improving survival rates for infants born with congenital heart defects.

Graphene composite may keep wings ice-free

A thin coating of graphene nanoribbons in epoxy has been proven effective at melting ice on a helicopter blade. The coating, developed by Rice University, may be an effective real-time de-icer for aircraft and other surfaces exposed to winter weather, reducing the need for glycol-based chemicals.

SourceRice University·JournalACS Applied Materials & Interfaces·DateJan 25, 2016

Microwaved nanotubes come up clean

Researchers at Rice University and Swansea University have developed a two-step process using microwaves and chlorine to remove iron catalyst residues from carbon nanotubes. This method makes the nanotubes more pristine and suitable for applications such as drug delivery and solar panels.

SourceRice University·JournalRSC Advances·DateJan 22, 2016

Graphene oxide 'paper' changes with strain

Rice researchers found that graphene oxide layers change their mechanical properties depending on the strain rate, making it brittle when pulled fast but more pliable under slow stress. This discovery can help build three-dimensional structures from two-dimensional materials for various applications.

SourceRice University·JournalNano Letters·DateJan 19, 2016

New tool puts accurate DNA analysis in fast lane

Researchers at Rice University have created a new tool to analyze DNA in its native conditions, reducing analysis time from months to hours. The method generates more accurate results and can be used to build a comprehensive database of thermal behaviors of genetic molecules.

SourceRice University·JournalNature Communications·DateJan 19, 2016

Nano-hybrid materials create magnetic effect

Scientists at Rice University and Montreal Polytechnic designed computer simulations to investigate the electromagnetic properties of graphene-boron nitride hybrids. The researchers found that these hybrid materials exhibit both electronic and magnetic properties, which could be useful in spintronic and nano-transistor applications.

SourceRice University·JournalCarbon·DateJan 13, 2016

Use small plates to lose weight

A recent study found that smaller plates can lead to a 30% reduction in food consumption on average, particularly when diners are self-serving their portions. The research also discovered that consumers who are unaware they are being monitored are more likely to benefit from the use of smaller plates.

SourceCornell Food & Brand Lab·JournalJournal of the Association for Consumer Research·DateJan 12, 2016

A new twist in genetic switches

Rice University researchers found that a master regulator's activity is determined by kinetics, not thermodynamics. The study revealed the 'molecular stripping' process, which quickly stops protein production.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateDec 21, 2015

Aryeh Warmflash wins NSF CAREER Award

Aryeh Warmflash, a Rice University professor, has received a prestigious NSF CAREER Award to investigate the mechanisms of embryonic cell differentiation. He aims to develop theoretical models to predict patterns of cell development and engineer embryonic-like systems.

Inflammation can fan the flames of depression

Researchers at Rice University and Ohio State University found that chronic inflammation is linked to depression, with concentrations of inflammatory markers CRP and IL-6 elevated by up to 50% in patients. Activities like yoga, meditation, NSAIDS, and exercise can help treat depression caused by chronic inflammation.

SourceRice University·JournalAmerican Journal of Psychiatry·DateDec 18, 2015

Superhydrophobic coating protects without the price

Researchers at Rice University and Swansea University have developed a new class of superhydrophobic nanomaterials that are inexpensive, nontoxic, and can be applied to various surfaces via spray- or spin-coating. The coating is equivalent in performance to commercial coatings that employ hazardous fluorocarbons.

SourceRice University·JournalACS Applied Materials & Interfaces·DateDec 9, 2015

Nanotube letters spell progress

The Rice researchers used experiments and simulations to study the stiffness of joined nanotubes and found that some types are tougher than others, with all having potential uses in macroscale structures. The team discovered that the X's were the stiffest and most able to bounce back to nearly their original shapes.

SourceRice University·JournalNano Letters·DateDec 7, 2015

Nanoscale drawbridges open path to color displays

Researchers at Rice University develop a new method for building 'drawbridges' between metal nanoparticles, allowing for the creation of full-color displays. The technique involves anchoring pairs of gold nanoparticles to a glass surface and applying a small voltage to create a conductive silver bridge that can be switched on and off.

SourceRice University·JournalScience Advances·DateDec 4, 2015

Red means 'go' to therapeutic viruses

Rice University researchers use engineered viruses that respond to red light to overcome the challenge of delivering genes into host cells' nuclei. By incorporating light-responsive proteins, they successfully control viral activity and gene expression in target cells.

SourceRice University·JournalACS Nano·DateDec 1, 2015

Tiny octopods catalyze bright ideas

Researchers at Rice University have created nanoparticles that can function as both catalysts and plasmonic sensors. These tiny octopods, composed of gold and palladium, enhance chemical reactions while retaining their optical properties. This breakthrough may lead to more efficient industrial processes and sun-driven chemical reactions.

SourceRice University·JournalScientific Reports·DateNov 30, 2015

Chemical design made easier

Rice University scientists have developed a metal-free process to synthesize dozens of organocatalysts, which promise to speed up the making of novel chemicals, including drugs. The new tools eliminate the need for transition metals and simplify chemical processes.

SourceRice University·JournalAngewandte Chemie International Edition·DateNov 24, 2015

Rice wins $2.4 million to study many-antenna wireless

The research aims to investigate the feasibility of using many-antenna base stations to serve multiple users simultaneously, addressing scalability and interference issues. By leveraging ArgosNet, a custom-built experimental test bed, the team will advance MIMO technology to meet the 1,000x data challenge in 5G networks.

No lens? No problem for FlatCam

Researchers developed patented prototypes of FlatCam, a thin sensor chip that processes sensor measurements into images and videos. The technology decouples the parameters of light collection and device thickness, enabling large sensors with thin devices.

Cereal science

Researchers at San Diego State University have discovered a new phenomenon in materials science using puffed rice cereal. They found that highly porous, brittle materials can deform differently depending on compaction velocity, with three distinct deformation patterns emerging at low, medium, and high velocities.

SourceSan Diego State University·JournalNature Physics·DateNov 18, 2015

Rice makes light-driven nanosubmarine

The researchers built single-molecule submersibles powered by ultraviolet light, achieving speeds of less than 1 inch per second but exceeding expectations for molecular motion. The study shows an enhancement in diffusion of 26 percent, outperforming Brownian motion.

SourceRice University·JournalNano Letters·DateNov 16, 2015

Clay makes better high-temp batteries

Researchers at Rice University have developed clay-based electrolytes that can supply stable electrochemical power in temperatures up to 120 degrees Celsius, addressing a challenge for rechargeable lithium-ion batteries. The materials offer thermal stability and wetting properties, enabling good contact with electrodes.

SourceRice University·JournalACS Applied Materials & Interfaces·DateNov 10, 2015

Rice U. paper: End 'stem cell tourism'

A new paper by Rice University experts warns that unproven stem cell-based interventions are causing harm to patients and hindering scientific progress. The authors argue that public policy is needed to reduce 'stem cell tourism' and promote responsible research.

SourceRice University·JournalBMC Medical Ethics·DateNov 9, 2015