Articles tagged with Metabotropic Glutamate Receptor Signaling
Researchers have discovered a surprising diversity of metabotropic glutamate receptor-beta arrestin interactions, which could help explain why previous drugs targeting these receptors have failed. The studies, led by Weill Cornell Medicine investigators, provide a foundational model for future mechanistic and drug-development work.
A new class of photoswitchable small molecule drugs has been developed to restore key visual functions in animal models of blindness. These compounds mimic the function of photoreceptor cells and show remarkable effectiveness at restoring sight using a simple and potentially patient-friendly approach.
A study has identified a gene, RANBP1, that appears to play a significant role in raising the risk of severe subtypes of autism and other genetic diseases. The findings suggest that disruptions in brain signaling networks may be good targets for future research and potentially lead to new treatment opportunities.