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Synaptic strength regulates sleep quantity and quality

Researchers developed a novel molecular tool, SYNCit-K, that enhances synaptic strength, leading to induced sleep and improved sleep quality in mice. The study reveals the role of synaptic connections in controlling sleep homeostasis.

SourceInternational Institute for Integrative Sleep Medicine, University of Tsukuba·JournalScience·DateSep 30, 2024

Star cells in the brain render memory flexible

Researchers found that astrocytes regulate cognitive flexibility by releasing D-serine and glutamate, which integrates synaptic plasticity. Heterosynaptic long-term depression is mediated by astrocytes, critical for memory modification.

SourceInstitute for Basic Science·JournalBiological Psychiatry·TypeExperimental study·DateDec 21, 2021