Articles tagged with Molecular Structure
Scientists have mapped the structure of a protein complex believed to influence cancer cell transformation, enabling potential development of unique cancer-fighting drugs. The Cdc42/GDI complex is a key regulator in both normal and cancerous cells.
Researchers at UNC-CH successfully created six-molecule water rings, mimicking natural ice structure. This achievement aims to boost knowledge of water's unique properties and hydrogen bonding forces.
Scientists at Brookhaven National Laboratory create a range of metallic tags to label proteins and molecules, enabling the study of molecular structures and behavior. These tags also facilitate the tracking of antibodies and drugs within cells, potentially leading to breakthroughs in disease diagnosis and treatment.
Researchers at Max-Planck-Gesellschaft have solved the three-dimensional structure of fumarate reductase dimer using X-ray crystallography. The enzyme plays a crucial role in anaerobic bacterial metabolism, and its structure reveals an electron transfer pathway from haem groups to FAD and then to fumarate reduction site.
The American Heart Association awarded Gold Heart Awards to Edmond M. Hoffman and Harold C. Strauss for their significant contributions to the organization over several decades. Their work includes promoting increased federal funding of biomedical research and relocating the National Center from New York City to Dallas.
Researchers at University of North Carolina at Chapel Hill and Rockefeller University have discovered that mammalian chromosomes end in loops, also known as telomeres. This finding has significant implications for our understanding of cell aging and cancer, providing a new way to think about molecular mechanisms.
Scientists discovered a common viral harpoon protein structure among measles, mumps and respiratory syncytial viruses. This finding suggests that these viruses may be related to HIV, influenza and Ebola viruses, potentially leading to the development of new drugs.
Scientists Nori Yamaguchi and Harry Gibson have developed a reversible process to form supramolecular polymers, which can be used to create fibers or transport target molecules. The polymers are formed through hydrogen bonding and can be undone at the molecular level using heat or pH.
Scientists have discovered the molecular structure of ZAG, a protein linked to severe weight loss in cancer patients. The discovery provides crucial insights into how ZAG promotes fat breakdown, paving the way for potential treatments for clinical obesity and related conditions.
Researchers at New York University have successfully constructed a machine from synthetic DNA molecules, featuring two rigid arms that can be rotated between fixed positions. This achievement marks a significant step towards developing nano-robots and molecular manufacturing capabilities.
Researchers have determined the first structure of a functional protein unit involved in neurofibromatosis, which regulates Ras and contributes to tumor growth. The study confirms mechanistic ideas about neurofibromin's function and links NF1 to cancerogenesis.
The study reveals human beta-tryptase is a ring-like tetramer with active sites facing a central pore. Its unique architecture explains many of its distinct biochemical properties and will facilitate understanding of its role in health and disease.
Researcher Robert Connelly uses tensegrities to model molecular structures like buckminsterfullerenes, which have unique geometric stability. His work provides insights into the behavior of certain-shaped molecules and could lead to a catalogue of stable tensegrity structures.
Scientists at UC Berkeley designed a protein that toggles between two structures upon binding a small molecule, enabling detection of carcinogens like benzene. The newly designed protein could also be used as a molecular switch or zipper to join proteins together.
Researchers use extreme X-ray power to 'movie' myoglobin protein, resolving decades-old structure-function riddle. This breakthrough enables drug developers to design better drugs by understanding dynamic molecular interactions.