Articles tagged with Protein Engineering
A research team led by Professor Kam-bo Wong engineered thermophilic enzymes to increase their activity at high temperatures without compromising stability. The findings provide insights into the design of biotechnologically important enzymes.
Engineered proteins mimic titin, a key muscle protein, to create a tough yet extensible scaffold for muscle regeneration. The biodegradable biomaterial could aid in the healing process by allowing new tissue to grow across injuries.
James A. Wells, a UCSF professor and director of the small molecule discovery center, has made groundbreaking contributions to protein engineering and discovery. He integrates multiple disciplines to design molecules that selectively activate or inhibit cellular processes.
The method allows researchers to explore protein function and find new drug targets, with potential applications in gene therapy and agricultural genetic engineering. The 'control switch' provides precise control over protein activity levels.
A research team developed an engineered protein that effectively neutralizes Staphylococcus aureus toxin, preventing symptoms in rabbits and reversing illness after exposure. The protein has potential advantages over antibodies, including smaller size and faster clearance from the body.
Scientists create artificial mechanism of allosteric control based on mechanical tension, allowing for controlled switching of proteins in living cells. The breakthrough could lead to targeted pharmaceutical drugs with reduced side effects and improved understanding of protein molecular architecture.
Researchers have developed a technology to engineer proteins as widely adaptable bioelectronic sensors for detecting specific chemicals. The engineered proteins, when attached to electrodes, can produce an electric signal reflecting the chemical's identity and concentration.