Jin Kim Montclare, an associate professor at NYU Tandon School of Engineering, has been recognized as a rising star in chemical engineering. Her lab's research on engineered proteins has made breakthroughs in detoxifying organophosphates and developing environmentally responsive hydrogels.
Researchers at Berkeley Lab have successfully reengineered a building block of a geometric nanocompartment, allowing for the transfer of electrons and enabling new functionalities. The introduction of iron-sulfur clusters expands the potential of nanocompartments as custom-made chemical factories.
Researchers created novel, self-assembling nanoscale proteins capable of binding small molecules, resulting in fibers that crossed the diameter barrier to the microscale. This breakthrough advances tissue engineering and drug delivery, enabling potential applications for dual-purpose scaffolds and efficient drug delivery.
A new engineered protein from a reaper spider's venom may offer a promising candidate for therapeutic serums or vaccination against other venoms. The protein provides effective protection against the effects of pure spider venom in animal models.
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David A. Estell, a Genencor researcher, received the Enzyme Engineering Award for his work on protein engineering and developing efficient proprietary technology for producing advanced biofuels. He has also initiated new technology development and holds over 70 issued U.S. patents.
A research team led by Professor Kam-bo Wong engineered thermophilic enzymes to increase their activity at high temperatures without compromising stability. The findings provide insights into the design of biotechnologically important enzymes.
Engineered proteins mimic titin, a key muscle protein, to create a tough yet extensible scaffold for muscle regeneration. The biodegradable biomaterial could aid in the healing process by allowing new tissue to grow across injuries.
James A. Wells, a UCSF professor and director of the small molecule discovery center, has made groundbreaking contributions to protein engineering and discovery. He integrates multiple disciplines to design molecules that selectively activate or inhibit cellular processes.
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The method allows researchers to explore protein function and find new drug targets, with potential applications in gene therapy and agricultural genetic engineering. The 'control switch' provides precise control over protein activity levels.
A research team developed an engineered protein that effectively neutralizes Staphylococcus aureus toxin, preventing symptoms in rabbits and reversing illness after exposure. The protein has potential advantages over antibodies, including smaller size and faster clearance from the body.
Scientists create artificial mechanism of allosteric control based on mechanical tension, allowing for controlled switching of proteins in living cells. The breakthrough could lead to targeted pharmaceutical drugs with reduced side effects and improved understanding of protein molecular architecture.
Researchers have developed a technology to engineer proteins as widely adaptable bioelectronic sensors for detecting specific chemicals. The engineered proteins, when attached to electrodes, can produce an electric signal reflecting the chemical's identity and concentration.