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Selective boron-heteroatom group exchange reactions

Researchers at ShanghaiTech University have developed a highly selective method for exchanging functional groups on boron atoms in organic compounds. This strategy has been successfully applied to sugar-derived diboron compounds, enabling the efficient synthesis of complex molecules and exhibiting potential applications in drug discovery.

SourceChinese Chemical Society·JournalCCS Chemistry·TypeExperimental study·DateOct 8, 2025

Notre Dame research may have important implications for combating diabetes

University of Notre Dame biochemist Anthony S. Serianni's research provides new perspectives on sugar breakdown in the human body, particularly for diabetic patients. The study discovered an unexpected reaction pathway involving a novel rearrangement of the carbon backbone, undermining prevailing assumptions about sugar degradation.

SourceUniversity of Notre Dame·JournalJournal of the American Chemical Society·DateDec 12, 2012