Researchers have discovered a method to deliver a natural suppressor of the immune response, HLA-G, directly to dendritic cells using microscopic beads. This approach shows promise in creating 'designer' immune cells that can tolerate transplanted organs. The therapy could potentially replace current anti-rejection drugs and improve pa...
A new prototype cell phone uses holographic lens-free imaging to accurately identify smaller particles such as E. coli in saliva or blood samples, enabling rapid diagnosis of diseases like HIV and malaria. The technology also has potential for monitoring water quality and detecting hazardous microparticles in disaster situations.
Researchers have developed biodegradable polymers called polyketals that can deliver drugs, proteins, and snippets of ribonucleic acid to specific areas in the body. The microparticles degrade quickly into biocompatible compounds, reducing inflammation.
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Preeclampsia researchers found specific proteins in placentas that damage maternal blood vessels, including plasminogen activator inhibitor-1 and soluble Flt-1. Microparticles from the placenta contain high levels of a mysterious protein with unknown function.
Researchers at Medical College of Wisconsin discovered that high levels of endothelial-derived microparticles inhibit growth and migration of endothelial cells in the mitral valve tissue. This finding may help prevent endothelial injury in valvular disease and other forms of heart disease.
Research at Michigan Medicine has discovered that inflammatory molecules and immune system cells play a major role in the formation of blood clots in veins, known as deep vein thrombosis (DVT). The study found that mice with high levels of P-selectin developed larger blood clots and more inflammatory cells in their vein walls.
Research by Dr. Marja J. van Wijk reveals that microparticles can damage blood vessels and disrupt their function, contributing to pre-eclampsia. Oestrogen administration may improve vessel functioning in affected women.
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