Researchers from Tohoku University developed a unique chemical reaction to attach two distinct functional molecules to the N-terminus of peptides with a glycine amino acid, achieving site-selective modification and stable carbon-carbon bonds. The method shows potential for labeling diverse peptides and larger proteins for purification,...
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A team of researchers has determined the detailed mechanism of cyclization catalyzed by the cyclization domain of cyclic β-1,2-glucan synthase from Thermoanaerobacter italicus. The study reveals that the enzyme produces β-glucosidase-resistant compounds and features a transglycosylation reaction.
Researchers at Kyoto University have determined the magnitude of spin-orbit interaction in acceptor-bound excitons in a semiconductor. The study revealed two triplets separated by a spin-orbit splitting of 14.3 meV, supporting the hypothesis that two positively charged holes are more strongly bound than an electron-and-hole pair.
Scientists at University of Utah and University of Massachusetts Amherst uncover the physics behind dopant-polymer interactions that explain inconsistent conductivity issues in organic materials. The discovery reveals that a critical mass of electrons triggers collective screening, allowing rest of electrons to flow unimpeded.
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Researchers discover how S1P molecules are released from SPNS2 protein via small cavities, enabling potential treatment for inflammatory diseases. The study provides a foundation for designing future drugs targeting the protein.
Researchers at Tokyo Metropolitan University have developed a novel approach to create nanoscrolls with improved control over nanostructure. The team achieved tight rolls with scrolls up to five nanometers in diameter and multiple microns in length, opening doors for new applications in catalysis and photovoltaic devices.
Scientists have successfully discovered the mechanism of trion generation using a tip-enhanced cavity-spectroscopy system. This approach enables nanoscale control and investigation of trion emission properties.
A team of researchers has identified the intrinsic interactions responsible for light-induced ferroelectricity in SrTiO3. By measuring fluctuations in atomic positions, they found that mid-infrared excitation suppresses certain lattice vibrations, leading to a more ordered dipolar structure.
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A new study at BESSY II has provided deeper insights into the ordering processes and diffusion phenomena in High-Entropy Alloys. The team analysed samples of a Cantor alloy, revealing local atomic structures using element-specific EXAFS and Reverse Monte Carlo analysis.
Researchers have developed a model-free approach to identify topological systems, enabling the discovery of new materials. The method uses experimental approaches to measure topologically protected soft or fragile spots in unknown mechanical metamaterials.
Researchers at Worcester Polytechnic Institute have developed a material to selectively oxidize urea in water, producing hydrogen gas. The material, made of nickel and cobalt atoms with tailored electronic structures, enables the efficient conversion of urea into hydrogen through an electrochemical reaction.
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Researchers developed a general A-site alloying strategy to prepare noble metal-occupied MAX phases, enabling the creation of over 100 materials with diverse compositions and crystal structures. These materials exhibit superior catalytic performance, particularly in alkaline hydrogen evolution reactions.
Researchers at Nagoya University used AI to analyze image data of polycrystalline silicon and discovered staircase-like structures that cause dislocations during crystal growth. The study sheds light on the formation of dislocations in polycrystalline materials, which can affect electrical conduction and overall performance.
A team of researchers at Tohoku University has developed a novel visualization method to study the behavior of hydrogen atoms in alloys. They successfully filmed the flow of hydrogen atoms in pure nickel, revealing that they preferentially diffuse through grain boundaries with large geometric spaces.
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Researchers have successfully fabricated a self-assembling photonic cavity with atomic-scale confinement, bridging the gap between nanoscopic and macroscopic scales. The cavities were created using a novel approach that combines top-down and bottom-up fabrication techniques, enabling unprecedented miniaturization.
Researchers have discovered a root cause of Barth syndrome, a deadly metabolic illness, by analyzing faulty cardiolipin molecules and their interaction with cytochrome c. The study used solid-state NMR technology to demonstrate the structural changes that lead to toxic oxidation in mitochondrial membranes.
Researchers discovered a mixture of ring shapes unique to glass and those resembling crystals, with specific areas showing degree of order or regularity despite apparent disorder. The findings contribute to understanding phase-transitions and provide mathematical descriptions for controlling material structures and properties.
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Researchers at TU Delft have discovered amorphous silicon carbide, a material with exceptional strength and scalability, making it suitable for ultra-sensitive microchip sensors. Its tensile strength of 10 GPa is unprecedented in materials science.
Researchers have engineered a range of new single-walled transition metal dichalcogenide (TMD) nanotubes with different compositions, chirality, and diameters. The ability to synthesize diverse structures offers insights into their growth mechanism and novel optical properties.
Scientists have discovered the open and closed states of the coronavirus E ion channel, which could help develop antiviral drugs to reduce inflammation. The study's findings provide insights into the channel's structure and function, allowing researchers to design molecules that can bind to it and prevent inflammation.
The UCLA-led team has developed a solution to improve cryo-electron microscopy's imaging capabilities for smaller protein molecules, enabling higher-resolution images. This advance is expected to help researchers identify specific locations on proteins that can be targeted for therapeutic purposes.
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The new resonators exhibit a record low UV light loss, enabling the development of miniaturized devices for applications such as spectroscopic sensing, underwater communication, and quantum information processing. The researchers achieved this by combining optimized design and fabrication techniques with amorphous alumina materials.
Scientists fabricate QADs with engineered quantum hole states, exhibiting novel transport properties and unique quantum phenomena. The structures' robustness against environmental influences enables exploration of novel quantum phenomena and material technologies.
Scientists have developed a new approach to study molecular behavior in confined spaces, allowing for real-time tracking of individual molecules within nanofluidic structures. This breakthrough enables the use of single-photon emitters as nanoscale probes, providing unprecedented insights into molecular properties and behaviors.
A study led by Weill Cornell Medicine researchers found that some ion channels can rearrange into a larger structure, enabling drug delivery. The discovery solves a long-standing mystery about ion channel dynamics and has implications for pharmaceuticals.
Researchers at NUS have developed a technique to precisely control the alignment of supermoiêre lattices using golden rules, expanding tunable material properties for diverse applications. They fabricated 20 moiêre samples with accuracy better than 0.2 degrees.
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Researchers from The University of Warwick and The University of Manchester have solved the long-standing puzzle of why graphene is permeable to protons. Protons are strongly accelerated around nanoscale wrinkles in perfect graphene crystals, which could lead to more sustainable hydrogen production.
Researchers at Tokyo Institute of Technology have developed a novel ferroelectric semiconductor memory device with a 100 nm channel length, enabling high-density storage and seamless integration with existing semiconductor technologies. The device exhibits typical resistive switching, high on/off ratio, large memory window, and good re...
Dr. McKay will investigate the chemical composition of chromophores in DOM using advanced analytical tools and conduct measurements at the National High Magnetic Field Laboratory. His research aims to enhance predictions regarding DOM behavior and reactivity in the environment.
Researchers have found an unusual ultrafast motion in layered magnetic materials, which could lead to breakthroughs in high-speed nanomotors for biomedical applications. The discovery was made using cutting-edge ultrafast probes and facilities, revealing a mechanical response across the entire sample.
A new study from the University of Chicago has laid out the internal structure of polyelectrolyte complexes, a special kind of molecular assembly that helps cells keep themselves organized. The researchers used a combination of simulations and neutron scattering to determine the precise structure of these molecules, which could lead to...
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A collaborative research team created an experimental platform to control the atomic-level structure of high-entropy alloy surfaces and test their catalytic properties. Their study found that the surfaces performed better in oxygen reduction reactions compared to other materials, indicating a 'pseudo-core-shell-like structure' contribu...
A team of scientists from Chemnitz University of Technology has successfully synthesized two-dimensional lead layers using a novel method. The researchers were able to comprehensively describe the structures of these layers, which could become relevant in the development of novel electronic systems and quantum materials.
Researchers at WVU have developed a way to view synthetic DNA at the atomic level, enabling them to understand how to change its structure for enhanced scissor-like function. This breakthrough could lead to new technology for medical diagnoses and treatments, including potential therapies for diseases like retinal degeneration and cancer.
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Researchers at Rice University have discovered a metal oxide that can enable terahertz technology for quantum sensing. The material, strontium titanate, exhibits unique properties that allow it to interact strongly with terahertz light, forming new particles called phonon-polaritons.
Researchers at Tokyo University of Science successfully synthesized tanzawaic acid B in large amounts, paving the way for new antibiotic development. The breakthrough method could lead to creation of various compounds for pharmaceuticals, including new antibiotic candidates.
Lancaster University researchers have developed a novel scanning thermal microscopy approach to directly measure the heat conductivity of two-dimensional materials. This breakthrough enables the creation of efficient waste heat scavengers generating cheap electricity, new compact fridges, and advanced optical and microwave sensors and ...
Researchers have developed a novel approach to generate highly directional single photons using a quantum emitter in a one-dimensional waveguide. This design improves extraction efficiency and reduces emission time uncertainty by exploiting the Purcell effect, offering a promising solution for quantum technologies.
A recent study by the Eustermann group at EMBL Heidelberg reveals that DNA packaging into hexasomes impacts the function of enzymes involved in gene regulation. The researchers used cryo-electron microscopy to visualize the molecular processes of how this packaging regulates genome expression and maintenance.
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Researchers at the University of Liverpool have developed a mathematical algorithm that can predict the structure of any material just by knowing its atoms. This breakthrough accelerates identification of new materials and their properties, paving the way for sustainable technologies.
A new study reveals that the protein complex BCDX2 plays a critical role in DNA repair, suggesting mutations in this complex could lead to cancer. The research also highlights the importance of screening for mutations in people with a family history of breast and ovarian cancers.
Researchers at the University of Queensland have uncovered the atomic structure of the Langya virus, a highly infectious virus with pandemic potential. The study aims to develop broad-spectrum human vaccines and treatments for Henipaviruses, which cause severe disease and have the potential to get out of control.
Researchers at USTC developed a novel catalyst synthesis strategy to optimize hydrogen evolution reaction (HER) activity and stability. The strategy involves adjusting the electronic structure of CoSe2 nanobelts, resulting in high-efficiency HER performance similar to commercial Pt/C catalysts.
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A new study has determined the atomic-level structure of a zinc-transporter protein, showing how it regulates zinc levels inside cells through a built-in sensor. The protein acts as a dimer, using feedback to control its activity based on zinc levels.
Researchers have revealed key atomic structures of actin filament ends using cryo-electron microscopy. The study provides fundamental insights into the mechanism behind actin filament polarity, shedding light on disorders such as muscle weakness and heart problems.
A new study by Duke University researchers reveals that the amount of toxic elements leaching out of coal ash depends largely on its nanoscale structure. The discovery highlights the complexity of coal ash as a material and emphasizes the need for closer examination of fine details within the ash to understand environmental risks.
A new study reveals the molecular structure of UCP1, allowing scientists to develop therapeutics that activate it to burn excess calories. This breakthrough could combat obesity and related diseases like diabetes by activating brown fat tissue.
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A team at Penn State has produced high-resolution images of SARS-CoV-2's protease protein and polyprotein complex. The research reveals a consistent order in which the proteins are cleaved, potentially supporting more efficient antiviral drugs.
A team of researchers used 3D-electron diffraction/micro-crystal diffraction to determine the structure of Levocetirizine dihydrochloride, an over-the-counter oral antihistamine. This breakthrough allows for a better understanding of its properties and potential applications.
Researchers use spectroscopic imaging scanning tunneling microscope to map atomic positions and measure electric charge, revealing link between electron density and atomic arrangements. The discovery sheds light on the emergence of a 'charge density wave' that distorts lattice vibrations and locks atoms in place.
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Researchers have developed software to remove signal interference from neutron experiments under megabar pressures. This enables the accurate extraction of data on extraordinary atomic structures of materials.
Researchers propose a new bonding theory that illustrates how each boron atom satisfies the octet rule and how alternating σ bonds further stabilize the 2D sheet. The theory introduces a new form of resonance, allowing delocalization of σ electrons within the plane.
Researchers at Argonne National Laboratory and University of Chicago developed a hybrid simulation process using IBM quantum computers to solve electronic structure problems. The new method uses classical processing to mitigate noise generated by the quantum computer, paving the way for future improvements.
Researchers from Japan have synthesized two di-superatomic molecules composed of Ag and evaluated the factors involved in their formation. The study found that a twist between the two icosahedral structures stabilizes the nanocluster by shortening the distance between them. Additionally, the presence of Pd and Pt central atoms was foun...
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Researchers at Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively breaks carbon-hydrogen bonds, suggesting ways to engineer it for producing desired products. The detailed structure reveals how the enzyme operates under ordinary conditions and produces few unwanted byproducts.
High-entropy metal telluride superconductors exhibit unique properties due to structural disorder and atomic vibrations. The discovery sheds light on the coupling between electrons and lattice vibrations, potentially leading to exotic superconductivity mechanisms.
Researchers at the University of Missouri are acquiring a new transmission electron microscope (TEM) with a $800,000 grant from the National Science Foundation. The TEM will allow them to conduct experiments in real-time and gain a greater understanding of material structure at an atomic level.
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Researchers have made the first accurate image of the proton using neutrinos instead of light as the probe in the MINERvA experiment. The study provides measurements of the proton's structure with unbound protons, helping to build more complete theories of neutrino interactions.
Researchers developed a chemical scissors-mediated structural editing strategy to regulate the structure and elemental composition of MAX phases/MXenes. This approach enables the creation of novel MAX phase and MXene materials with improved functional applications.
Researchers from Tokyo Metropolitan University have successfully threaded indium atoms into bundles of transition metal chalcogenide nanofibers, creating a unique nanostructure. The resulting metallic nanowires exhibit properties suitable for flexible wiring in nanocircuitry.