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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Nanoscale worms provide new route to nano-necklace structures

Researchers developed a novel technique to craft nanometer-scale necklaces using tiny star-like structures threaded onto a polymeric backbone. The technique creates hybrid organic-inorganic shish kebab structures from semiconducting materials with unique properties.

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New transitory form of silica observed

A team of scientists has discovered five new forms of silica under extreme pressures at room temperature, revealing a four-to-six configuration shift in the deep Earth. The findings provide valuable insights into the transition between different chemical phases under high-pressure conditions.

Second natural quasicrystal found in ancient meteorite

A team from Princeton University has discovered a second natural quasicrystal in an ancient meteorite, bringing to two the number of natural quasicrystals ever discovered. The newly found quasicrystal has a decagonal symmetry and is made up of aluminum, nickel, and iron.

Cells target giant protein crystals for degradation

Researchers at RIKEN Brain Science Institute engineered fluorescent protein that rapidly assembles into large crystals in living cells. Cells actively targeted the crystals for degradation, a process known as autophagy, suggesting potential evolutionary pressure to discourage crystal formation.

X-ray imaging of a single virus in 3-D

Researchers have successfully imaged the 3D structure of a giant mimivirus using an X-ray free-electron laser, without relying on crystal formation. This achievement paves the way for imaging important pathogenic viruses like HIV and influenza.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Beyond silicon: New semiconductor moves spintronics toward reality

A new semiconductor compound is bringing fresh momentum to the field of spintronics, an emerging breed of computing device that may lead to smaller, faster, less power-hungry electronics. The compound's unique low-symmetry crystal structure offers much greater flexibility, enabling precise control over conductivity and magnetism.

Announcing the winners of the 2015 Protein Society Awards

This year's winners are Dr. C. Robert Matthews, Dr. Eva Nogales, Dr. Marina Rodnina, Dr. Sachdev Sidhu, and Dr. Anna Mapp. They were honored for their groundbreaking research in protein folding mechanisms, structural biology, protein synthesis, engineering, and chemical biology.

The rarely understood ammonium carbonate monohydrate

Researchers have clarified the compound's phases, thermal expansion and hydrogen bonds, shedding new light on its properties. The study uses advanced methods to determine the crystal structure and electronic structure of ammonium carbonate monohydrate.

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Pictured together for the first time: A chemokine and its receptor

The study reveals that one chemokine binds to just one receptor in the CXCR4-chemokine complex and that the contacts between the receptor and its binding partner are more extensive than previously thought. This new information could aid the development of better small molecular inhibitors of CXCR4-chemokine interactions.

Researchers from MIPT predict properties of surface

Researchers from MIPT use the USPEX method to predict the structure and properties of rutile's surface. This resolves existing discrepancies between empirical and theoretical data, paving the way for understanding chemical reactions on the catalyst.

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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Integrated space-group and crystal-structure determination

The new SHELXT program solves the phase problem for single-crystal reflection data using a novel dual-space algorithm, extending resolution and accommodating missing data. With high success rates, it has already solved thousands of structures.

Stacking 2-dimensional materials may lower cost of semiconductor devices

Researchers at North Carolina State University discovered that stacking 2D materials can create semiconductor junctions with efficient charge transfer, even when the crystalline structures don't match. This discovery could make the manufacture of semiconductor devices an order of magnitude less expensive.

Penn researchers show commonalities in how different glassy materials fail

Penn researchers demonstrate that stiffness and strength scaling remain unchanged across various glassy materials, indicating a constant critical strain before catastrophic failure. This finding provides insight into the fundamental mechanism driving failure in glasses, suggesting cooperative motion of particles or atoms.

Unraveling the complexity of proteins

Researchers successfully analyzed all known complete proteomes using X-ray crystallography and homology modeling, covering 25% of protein clusters. The study highlights the potential for knowledge-based target selection to increase structural model production, particularly in eukaryotes and archaea.

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Asteroid impacts on Earth make structurally bizarre diamonds

New research from Arizona State University reveals that lonsdaleite is not a separate type of diamond but rather a structurally disordered form of ordinary diamond. The study found defects in the crystal structure caused by shock metamorphism, plastic deformation, or unequilibrated crystal growth.

New form of crystalline order holds promise for thermoelectric applications

Researchers at Vanderbilt University have discovered a new form of crystalline order that exhibits both crystal and polycrystalline properties. The 'interlaced crystals' arrangement has ideal properties for thermoelectric applications, which could increase power generation efficiency and reduce energy costs.

A greasy way to take better protein snapshots

Researchers at RIKEN developed a new technique to analyze protein structures by suspending crystals in a greasy substance, enabling the use of smaller samples and faster data collection. This breakthrough could lead to improved understanding of dangerous proteins, such as those containing mercury.

X-ray vision of photosynthesis

Researchers have used X-ray diffraction to investigate photosystem II, revealing structures yet unknown. The results show that photosystem II proteins are arranged within crystals as extended rows, similar to their natural environment.

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Figuring out how we get the nitrogen we need

Researchers have successfully crystallized carbon monoxide bound to the FeMo-cofactor of nitrogenase, a long-sought structure that could reveal the enzyme's mechanism. The breakthrough, achieved by Thomas Spatzal and colleagues, uses optimized crystallization methods and tiny crystal seeds to accelerate growth.

Synapses always on the starting blocks

Researchers at Max Planck Institute discover that neurotransmitter vesicles are already in close contact with the cell membrane before fusion occurs. This discovery provides insight into how synapses rapidly transmit information and could lead to new medical research benefits.

Towards controlled dislocations

A group of scientists from the US used atomic-resolution Z-contrast imaging and X-ray spectroscopy to analyze two types of dislocations in CdTe, a binary II-VI semiconductor. The study could lead to improved conversion efficiency in CdTe solar cells and advance understanding of crystal structure defects.

Crystallizing the DNA nanotechnology dream

Scientists at Harvard's Wyss Institute have designed the first large DNA crystals with precise depth and complex 3D features, enabling the creation of revolutionary nanodevices. The breakthrough uses a modular 'DNA-brick self-assembly' method to build complex structures with nanometer precision.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Breakthrough allows researchers to watch molecules 'wiggle'

A new crystallographic technique enables time-resolved crystallography, allowing researchers to study how molecular structures work. This breakthrough is expected to provide a major boost in areas of research that rely on understanding molecule function.

Longstanding bottleneck in crystal structure prediction solved

Researchers at Princeton University have overcome a major challenge in predicting material properties by accurately calculating the lattice energy of benzene to sub-kilojoule/mol accuracy. This breakthrough enables polymorphism to be resolved, a crucial step towards understanding material behavior and development of new materials.

2-D materials' crystalline defects key to new properties

Scientists have found that defects in a 2D material called tungsten disulphide can create unusual characteristics, making it useful for electronic devices and hydrogen gas liberation. The researchers used an advanced microscope to visualize the defects, revealing a low-energy barrier that allows them to be easily displaced.

Case Western Reserve University on track to become No. 1 synchrotron lab in world

The Case Center for Synchrotron Biosciences will assemble cutting-edge Nnew beamlines at Brookhaven National Laboratory, delivering ultra powerful x-rays to visualize nano-scale structures of molecules and proteins. The new facility will enable scientists to pinpoint disease-causing vulnerabilities and target therapeutic interventions.

Penn research helps uncover mechanism behind solid-solid phase transitions

Researchers from Penn and HKUST discovered a surprising mechanism facilitating one of the two main routes for solid-solid transitions. The process involves the parent phase producing liquid droplets, which then evolve into the daughter phase, revealing new insight into material development and natural processes.

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Protein secrets of Ebola virus

A team of scientists at UVA has obtained the crystal structure of a key Ebola virus protein, revealing a novel tertiary fold that could lead to insights into viral assembly and antiviral drug design. The study's results may provide a potential target for the development of new treatments for Ebola hemorrhagic fever.

Angling chromium to let oxygen through

Researchers have discovered a new semiconducting material that allows solid oxide fuel cells to operate at two-thirds lower temperatures than current technology. This breakthrough enables more efficient fuel cells with wider applications, including quieter, pollution-free power generation in vehicles and neighborhoods.

Continuing Bragg legacy of structure determination

Researchers at the University of Adelaide have made significant advances in crystallography, allowing them to study chemical reactions in their native state. The new technique uses a metal-organic framework to bind reactants and enables the examination of reaction products without isolating or growing crystals.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Computer simulations visualize ion flux

A team of researchers used computer simulations to study how ion flux works in voltage gated sodium ion channels. The results revealed that a specific amino acid, glutamic acid, plays a crucial role in regulating channel flux and enabling selective sodium influx.

Plug n' play protein crystals

Scientists from Aalto University create ordered structures by mixing oppositely charged proteins and virus particles, enabling modular functionalization with various ligands. The method opens possibilities for biomedical and materials science research.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Worm virus details come to light

The research reveals the viral capsid structure, showing similarities to other viruses, and identifies potential binding sites for modification. The findings may lead to new information on host-virus interactions and the development of custom-made viruses to target parasitic or pathogenic worms.

New material allows for ultra-thin solar cells

Researchers at Vienna University of Technology have created a semiconductor structure consisting of two ultra-thin layers, tungsten diselenide and molybdenum disulphide, which exhibits excellent optoelectronic properties. This material has the potential to be used in future low-cost solar cells with improved efficiency and flexibility.

Uncovering the 3-D structure of a key neuroreceptor

Scientists have determined the 3D structure of 5HT3-R, a receptor involved in conditions like chemotherapy-induced nausea and anxiety. The high-resolution structure reveals the receptor's molecular anatomy, providing insights into its function and potential targets for novel medicines.

Technique simplifies the creation of high-tech crystals

Researchers propose a new method to create defect-free crystals using inexpensive ingredients, dispelling current methods' reliance on difficult-to-synthesize particles. By adding polymers to colloidal suspensions, scientists can impose order on crystal formation and tailor crystal structures.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Neutron crystallography solves long-standing biological mystery

Scientists solved the long-standing question of whether ferryl heme in Compound I involves just an oxygen atom or a hydroxyl group, with implications for drug development. The study used neutron crystallography to determine the structure of Compound I at cryogenic temperatures.

Study helps unlock mystery of high-temp superconductors

Scientists have discovered a density wave structure in copper-oxide high-temperature superconductors, shedding light on their exotic properties. The breakthrough could lead to significant improvements in electricity delivery and technology.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Crowdsourcing the phase problem

Researchers develop a crowdsourcing game to tackle the phase problem, achieving successful results in low-resolution phasing puzzles. The approach leverages human pattern recognition capabilities to guide the search process.

Scientists capture most detailed images yet of tiny cellular machines

A team of researchers from the University of Wisconsin-Madison has captured the most detailed images yet of spliceosomes, which help make proteins in our bodies. The images reveal new details about how these cellular machines work and provide insight into the relationship between RNA and protein.

Nano world: Where towers construct themselves

Researchers develop method to control ordering of self-assembling structures, inducing reversible switching and transformation between arrangements. Nano-scale materials with specific properties are crucial for various applications in electronics, photovoltaics and biomimetic material synthesis.

Observing the random diffusion of missing atoms in graphene

Scientists at the University of Vienna observe random diffusion of a butterfly-shaped atomic defect in graphene, revealing a random walk through the crystal. The study uses high-resolution electron microscopy to track the defect's migration over time.

Eumelanin's secrets

Eumelanin, the primary pigment in human skin, hair, and eyes, has been found to absorb a broad spectrum of sunlight due to its unique physical arrangement. Researchers have identified that disorder in the material's structure plays a crucial role in its broadband blocking ability.

DJI Air 3 (RC-N2)

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NCNR neutrons highlight possible battery candidate

Analysis reveals unusual sodium absorption pattern in the crystal, caused by different charges and magnetic moments of manganese atoms. The discovery provides a basis for tailoring the properties of these materials, potentially leading to improved battery performance.

Edgy look at 2-D molybdenum disulfide

Scientists at Lawrence Berkeley National Laboratory have recorded the first observations of strong nonlinear optical resonances along the edges of a single layer of molybdenum disulfide. These one-dimensional edge states are key to enabling novel nanoelectronics and photonic devices.

Playing pool with carbon atoms

Scientists at the University of Arizona have developed a way to control graphene's crystal structure using an electric field. This breakthrough could lead to the creation of faster and more versatile transistors, which would enable faster computing and new applications for graphene in microelectronics.

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