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Diamonds are for temperature

Scientists have created tiny diamond-based probes that can measure temperature with high accuracy, from near-cryogenic cold to slightly above the melting point of aluminum. The probes use luminescent signals from green glowing diamond defects and can detect fast thermal variations.

SourceAmerican Institute of Physics·JournalApplied Physics Letters·DateJun 16, 2015

Insight into the Ebola virus nucleocapsid assembly mechanism

Researchers solved the structure of Ebola virus nucleoprotein core domain to 1.8 Å resolution, revealing RNA binding groove similarities with other viral NPs. The findings provide valuable insights into EBOV genome assembly and transcription mechanism, as well as potential antiviral therapies targeting RNP formation.

SourceSpringer·JournalProtein & Cell·DateMay 6, 2015

Making carboxyl(ate) friends

Researchers Luigi D'Ascenzo and Pascal Auffinger classify 17 carboxyl(ate) motifs in crystal structures using stereochemical considerations. They provide a systematic naming system and implications for crystal engineering, pharmaceutical research, and biomolecular sciences.

SourceInternational Union of Crystallography·JournalActa Crystallographica Section B·DateApr 14, 2015

Rodeo in liquid crystal

Researchers successfully created and controlled defect pairs in liquid crystals using optical tweezers. This achievement opens the door to controlling light flow using specific frequencies in liquid crystal photonic microdevices, with potential applications in photonics.

SourceSpringer·JournalThe European Physical Journal E·DateMar 31, 2015

New transitory form of silica observed

A team of scientists has discovered five new forms of silica under extreme pressures at room temperature, revealing a four-to-six configuration shift in the deep Earth. The findings provide valuable insights into the transition between different chemical phases under high-pressure conditions.

SourceCarnegie Institution for Science·JournalNature Communications·DateMar 20, 2015

Cells target giant protein crystals for degradation

Researchers at RIKEN Brain Science Institute engineered fluorescent protein that rapidly assembles into large crystals in living cells. Cells actively targeted the crystals for degradation, a process known as autophagy, suggesting potential evolutionary pressure to discourage crystal formation.

SourceRIKEN·JournalMolecular Cell·DateMar 12, 2015

Penn researchers show commonalities in how different glassy materials fail

Penn researchers demonstrate that stiffness and strength scaling remain unchanged across various glassy materials, indicating a constant critical strain before catastrophic failure. This finding provides insight into the fundamental mechanism driving failure in glasses, suggesting cooperative motion of particles or atoms.

SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateDec 9, 2014

A greasy way to take better protein snapshots

Researchers at RIKEN developed a new technique to analyze protein structures by suspending crystals in a greasy substance, enabling the use of smaller samples and faster data collection. This breakthrough could lead to improved understanding of dangerous proteins, such as those containing mercury.

SourceRIKEN·JournalNature Methods·DateNov 10, 2014

Synapses always on the starting blocks

Researchers at Max Planck Institute discover that neurotransmitter vesicles are already in close contact with the cell membrane before fusion occurs. This discovery provides insight into how synapses rapidly transmit information and could lead to new medical research benefits.

SourceMax-Planck-Gesellschaft·JournalNeuron·DateOct 27, 2014

Towards controlled dislocations

A group of scientists from the US used atomic-resolution Z-contrast imaging and X-ray spectroscopy to analyze two types of dislocations in CdTe, a binary II-VI semiconductor. The study could lead to improved conversion efficiency in CdTe solar cells and advance understanding of crystal structure defects.

SourceInternational Union of Crystallography·JournalActa Crystallographica Section A·DateOct 20, 2014

2-D materials' crystalline defects key to new properties

Scientists have found that defects in a 2D material called tungsten disulphide can create unusual characteristics, making it useful for electronic devices and hydrogen gas liberation. The researchers used an advanced microscope to visualize the defects, revealing a low-energy barrier that allows them to be easily displaced.

SourcePenn State·JournalNature Communications·DateSep 24, 2014

Protein secrets of Ebola virus

A team of scientists at UVA has obtained the crystal structure of a key Ebola virus protein, revealing a novel tertiary fold that could lead to insights into viral assembly and antiviral drug design. The study's results may provide a potential target for the development of new treatments for Ebola hemorrhagic fever.

Continuing Bragg legacy of structure determination

Researchers at the University of Adelaide have made significant advances in crystallography, allowing them to study chemical reactions in their native state. The new technique uses a metal-organic framework to bind reactants and enables the examination of reaction products without isolating or growing crystals.

SourceUniversity of Adelaide·JournalNature Chemistry·DateSep 7, 2014

Computer simulations visualize ion flux

A team of researchers used computer simulations to study how ion flux works in voltage gated sodium ion channels. The results revealed that a specific amino acid, glutamic acid, plays a crucial role in regulating channel flux and enabling selective sodium influx.

SourceUniversity of Vienna·JournalPLOS Computational Biology·DateSep 1, 2014

Plug n' play protein crystals

Scientists from Aalto University create ordered structures by mixing oppositely charged proteins and virus particles, enabling modular functionalization with various ligands. The method opens possibilities for biomedical and materials science research.

SourceAalto University·JournalNature Communications·DateAug 29, 2014

Worm virus details come to light

The research reveals the viral capsid structure, showing similarities to other viruses, and identifies potential binding sites for modification. The findings may lead to new information on host-virus interactions and the development of custom-made viruses to target parasitic or pathogenic worms.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateAug 18, 2014

New material allows for ultra-thin solar cells

Researchers at Vienna University of Technology have created a semiconductor structure consisting of two ultra-thin layers, tungsten diselenide and molybdenum disulphide, which exhibits excellent optoelectronic properties. This material has the potential to be used in future low-cost solar cells with improved efficiency and flexibility.

SourceVienna University of Technology·JournalNano Letters·DateAug 4, 2014

SLU scientists hit 'delete': Removing regions of shape-shifting protein explains how blood clots

Researchers at Saint Louis University discovered that deleting disordered sections of a protein's structure reveals the molecular mechanism of blood clotting. By crystallizing prothrombin, they found that the deleted version is activated to thrombin faster and provides key information on the mechanism of prothrombin activation.

SourceSaint Louis University·JournalProceedings of the National Academy of Sciences·DateJul 15, 2014