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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

New discovery improves use of optical tweezers

Researchers from the University of Gothenburg have developed a new method to improve the use of optical tweezers, allowing for more accurate measurements with less data and faster processing. This breakthrough enables the technique to be used in pharmaceutical research and study systems that are not in equilibrium.

Shedding a new light on optical trapping and tweezing

Wits physicists have developed a new device for manipulating and moving tiny objects, such as single cells in a human body or tiny particles in small volume chemistry, using the full beam of laser light. The device uses vector holographic trapping and tweezing to control and manipulate minute objects with high precision.

RIT collaborates on multi-university research exploring the quantum world

A Rochester Institute of Technology researcher is collaborating on a multi-university project exploring quantum science in levitated mechanical systems. The project aims to create and sustain a quantum state with levitated optomechanics using advanced sensing designs based on the 'optical tweezers' technique.

GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Optical tweezers steer a chemical reaction from just 2 atoms

Scientists have successfully trapped and manipulated two individual sodium and cesium atoms using optical tweezers, resulting in the creation of a new sodium-cesium molecule. This technique enables precise control over chemical reactions, paving the way for studying complex molecules and designer molecules for quantum applications.

UQ study shines a light to understand the body's balance system

A University of Queensland team has made a breakthrough in understanding the vestibular system, which controls balance and movement. Using optical tweezers, they were able to activate the vestibular system without the animal moving, allowing for the study of neural circuits in the brain that mediate vestibular perception.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

2+1 is not always 3

Researchers measured critical Casimir forces with two and three particles to demonstrate nonadditivity and show that these forces are crucial for designing micro-machines. The study used colloids immersed in fluid and optical tweezers to measure the effects of many-body interaction.

To touch the microcosmos

Researchers have developed a new technique called haptic optical tweezers, enabling scientists to 'feel' the microscopic structures under the lens. This technology allows users to explore the microworld by sensing and exerting piconewton-scale forces with trapped microspheres.

Elucidating energy shifts in optical tweezers

Physicists develop a guide to calculate energy level changes in atoms under optical tweezers' influence. Fictitious magnetic fields are shown to produce equivalent effects as real external fields.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

New optical tweezers trap specimens just a few nanometers across

Researchers at Stanford University School of Engineering have designed a novel light aperture that can stably trap objects as small as 2 nanometers using plasmonic technology. The device uses a silver and silicon dioxide structure to focus light and create a powerful, concentrated beam that can trap tiny particles.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Optical nanoantennas enable efficient multipurpose particle manipulation

Researchers at University of Illinois have demonstrated the use of arrays of gold Bowtie Nanoantenna Arrays for multipurpose optical trapping and manipulation of submicrometer- to micrometer-sized objects. This enables highly efficient, optical tweezers with low-input power densities, useful for optofluidic applications and manipulatin...

Are electron tweezers possible? Apparently so

Researchers from NIST and UVA successfully demonstrated the use of electron tweezers to move, position and assemble tiny particles at the nanoscale. Electron tweezers have the potential to offer a thousand-fold improvement in sensitivity and resolution compared to traditional laser optical tweezers.

Optical tweezers software now available for the iPad

Researchers have developed an iPad application for optical tweezers, overcoming limitations of computer mouse control. The multi-touch-based app allows for clear representation of particle systems and offers various techniques for movement.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Acoustic tweezers can position tiny objects

Researchers have developed acoustic tweezers that can position single cells or nanosized beads using sound waves, allowing for efficient manipulation without damaging live cells. The technology has significant advantages over existing methods in terms of versatility, miniaturization, and power consumption.

Liquid lens creates tiny flexible laser on a chip

Researchers create Liquid-Gradient Refractive Index (L-GRIN) lenses using water and calcium chloride, enabling precise control over light direction. These fluidic lenses can be fabricated on chips and have potential applications in optical tweezers and medical imaging.

DNA sewing machine

Researchers develop unique method to sew long DNA threads into shape using micron-sized hooks controlled by lasers, allowing for high-spatial resolution gene location detection. The technology has potential applications in DNA sequencing and molecular electronics.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Engineers demonstrate a new type of optical tweezer

Engineers at Harvard University have developed a novel optical tweezer that can perform calibrated force measurements with high precision. The device, consisting of a Fresnel Zone Plate fabricated on a glass slide, has the potential to revolutionize biological and microfluidic applications.

Media highlights in the Dec. 15 issue of Biophysical Journal

Researchers explore how heart muscle adjusts contractions based on protein spacing and DNA elasticity, revealing new insights into cellular control and potential applications for measuring picoscale forces. The studies also provide a more accurate model for single-molecule research.

MIT develops 'tractor beam' for cells, more

Researchers at MIT have successfully applied the concept of optical tweezers to manipulate and measure tiny objects on a microchip. Using infrared light, they were able to hold and move individual cells and other objects with unprecedented precision, opening up new possibilities for biological research and materials development.

Optical tweezers prove Einstein right

Researchers have successfully measured the back-flow effect in Brownian motion, a phenomenon Einstein predicted but overlooked 100 years ago. The discovery uses optical tweezers technology to detect this effect, confirming a key aspect of Brownian motion theory.

Teasing apart the molecules of life

Researchers devise new method combining optical trapping and single-molecule fluorescence to study DNA structural and mechanical changes. This technique allows scientists to study rare molecules essential for life and disease development.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.