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Using a single atom as a “camera” - visualization of light intensity and polarization beyond the resolution limit of optical microscopes -

Researchers use a single rubidium atom trapped in an optical tweezer as a scanning probe to image fine structures of light patterns with spatial resolution surpassing the diffraction limit. The technique successfully visualizes both light intensity and polarization distributions at the nanoscale.

SourceNational Institutes of Natural Sciences·JournalNature Communications·TypeExperimental study·DateMay 29, 2026
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Inverse synthetic aperture macroscopic Fourier ptychography enables super-resolution imaging of non-cooperative moving targets

Researchers develop ISAMFP, a computational framework that leverages natural target motion to enable super-resolution imaging of dynamic non-cooperative targets. By exploiting angular diversity and phase modulation, the method achieves high-frequency information recovery from sub-aperture intensity measurements.

SourceSmart Computational Imaging Laboratory (SCILab), Nanjing University of Science and Technology·JournalLaser & Photonics Review·DateMar 30, 2026

Toward high-speed, label-free live-cell imaging: Spatiotemporal-multiplexed fourier ptychographic diffraction tomography

Researchers developed STM-FPDT to overcome speed bottlenecks in conventional tomographic imaging. The technique enables parallel acquisition of multi-angle information, reducing acquisition time by 4.5-fold and enabling high spatiotemporal resolution observation.

SourceSmart Computational Imaging Laboratory (SCILab), Nanjing University of Science and Technology·JournalAdvanced Photonics·TypeImaging analysis·DateMar 30, 2026

From high complexity to accessible: PCA empowers lightweight, compact super-resolution microscopy

Researchers developed PCA-iSIM, a novel super-resolution microscopy system that enables high-resolution imaging of subcellular dynamics in living cells. The approach integrates PCA to extract dominant signal components and enhance robustness and precision in parameter estimation.

SourceSmart Computational Imaging Laboratory (SCILab), Nanjing University of Science and Technology·JournalLaser & Photonics Review·TypeImaging analysis·DateMar 29, 2026
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Tiny flows, big insights: microfluidics system boosts super-resolution microscopy

Researchers developed a dedicated microfluidics system to overcome limitations of existing methods in multiplexed super-resolution microscopy. The new platform precisely injects and removes solutions, allowing for high-quality imaging of proteins, specialized structures, and complex interactions within cells.

SourceUniversity of Göttingen·JournalACS Nano·TypeNews article·DateMar 3, 2026

Australian scientists uncover secrets of yellow fever

Researchers at the University of Queensland have captured high-resolution images of the yellow fever virus, shedding light on its structural differences between the vaccine strain and disease-causing variants. The study reveals that these differences impact how the immune system recognizes the virus.

SourceUniversity of Queensland·JournalNature Communications·TypeImaging analysis·DateNov 4, 2025
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Holographic precision, super-resolution vision: scientists reveal the hidden world of vital cellular structures

Researchers measured protein content and growth dynamics of individual biomolecular condensates without disturbing them, gaining insights for future drug development and disease modeling. The study revealed intricate nanoscale organization and complex internal architecture of these microscopic structures.

SourceNew York University·JournalJournal of the American Chemical Society·DateJul 16, 2025
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Microscopy method breaks barriers in nanoscale chemical imaging

A new microscopy technique, SIMIP, combines structured illumination with mid-infrared photothermal detection to achieve high-speed chemical imaging with superior resolution. The method outperforms conventional methods in terms of spatial resolution and chemical contrast.

SourceSPIE--International Society for Optics and Photonics·JournalAdvanced Photonics·DateApr 14, 2025

New imaging technology reveals inner workings of living cells

A new imaging technology has been developed that combines super-resolution imaging with artificial intelligence to reveal subcellular structures and dynamics in living cells. This breakthrough enables scientists to better understand the root causes of diseases, leading to improved treatments.

SourceUniversity of Technology Sydney·JournalNature Communications·TypeImaging analysis·DateApr 2, 2025

A closer look at biomolecular ‘silly putty’

Researchers used novel fluorogen imaging techniques to visualize biomolecular condensates, revealing distinct environmental and structural features. The study provides insights into the dynamic behavior of these condensates, which play a crucial role in various diseases.

SourceWashington University in St. Louis·DateMar 14, 2025
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

USTC develops compact device for super-resolution imaging beyond the diffraction limit

Researchers from USTC unveil planar optical device that enhances dark-field microscopy capabilities, achieving super-resolution imaging. The compact device uses a scattering layer and metallic film to generate dark-field speckle patterns, enabling high-contrast imaging with improved spatial resolution.

SourceUniversity of Science and Technology of China·JournalProceedings of the National Academy of Sciences·DateMar 9, 2025

Genoa Instruments, a deep-tech startup born from the Italian Institute of Technology, secures €1 million funding round led by Deep Blue Ventures to transform super-resolution optical microscopy

Genoa Instruments has secured €1 million funding to expand its market presence, develop new products, and democratize access to super-resolution microscopy. The company aims to enable researchers and professionals worldwide to access cutting-edge imaging technology.

SourceIstituto Italiano di Tecnologia - IIT·DateFeb 5, 2025
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Uncurling a single DNA molecule and gluing it down helps sharpen images

Researchers have developed a method to stretch and immobilize single DNA molecules, enabling detailed analysis. By controlling the shear force applied through liquid pressure flow and bonding the molecule to a substrate, scientists can distinguish between tiny biomolecular features with higher precision.

SourceAmerican Institute of Physics·JournalAIP Advances·DateJan 14, 2025

10,000 times faster than traditional methods: new computational framework automatically discovers experimental designs in microscopy

Researchers have developed an AI framework called XLuminA that autonomously discovers new experimental designs in microscopy. The framework performs optimizations 10,000 times faster than well-established methods, opening the path for exploring completely new territories in microscopy.

SourceMax Planck Institute for the Science of Light·JournalNature Communications·TypeComputational simulation/modeling·DateDec 10, 2024
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Fast super-resolved microscopy with a structured illumination and extended depth detection

Extended Depth-of-Field Random Illumination Microscopy (EDF-RIM) offers a breakthrough in fluorescence microscopy, combining super-resolution with extended depth-of-field detection. This innovation allows for efficient imaging of large and complex 3D structures, minimizing light exposure and acquisition time.

SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·DateNov 28, 2024

New imaging platform developed by Rice researchers revolutionizes 3D visualization of cellular structures

Researchers at Rice University developed soTILT3D, an innovative imaging platform that enables fast and precise 3D imaging of multiple cellular structures while controlling the extracellular environment. The platform improves upon conventional fluorescence microscopy by reducing background fluorescence and increasing imaging speed.

SourceRice University·JournalNature Communications·DateNov 26, 2024

A new method makes high-resolution imaging more accessible

Researchers at MIT have developed a new expansion technique to image nanoscale structures inside cells using conventional light microscopes. The method, which expands tissue 20-fold in a single step, allows for high-resolution imaging of organelles and protein clusters.

SourceMassachusetts Institute of Technology·JournalNature Methods·DateOct 11, 2024

Super-precise spectrometer enabled by latent information carried by photons

Researchers at the University of Warsaw developed a quantum-inspired super-resolving spectrometer that uses latent information carried by photons to improve spectral resolution. The device offers over a two-fold improvement in resolution compared to standard approaches and has potential applications in optical and quantum networks.

SourceUniversity of Warsaw, Faculty of Physics·JournalOptica·DateSep 12, 2024
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

New microscopes available as public resource draw a crowd to Woods Hole

The Marine Biological Laboratory has introduced two new microscopes for biological and biomedical research, providing a valuable resource for scientists and students. The instruments enable correlative imaging, allowing researchers to confirm results in different ways, and are expected to influence further development of advanced imagi...

SourceMarine Biological Laboratory·DateJul 8, 2024

Design and development of a novel light sheet fluorescence microscope

A novel light sheet fluorescence microscope, descSPIM, has been developed to facilitate 3D visualization of cleared tissues at a lower cost and with simplified design. The system successfully imaged various organs and tissues, including whole-brain samples and cancer models.

SourceJuntendo University Research Promotion Center·JournalNature Communications·TypeExperimental study·DateJul 2, 2024

Airborne single-photon lidar system achieves high-resolution 3D imaging

Researchers have developed a compact and lightweight single-photon airborne lidar system that can acquire high-resolution 3D images with a low-power laser. The system uses single-photon detection techniques to measure time-of-flight, enabling highly accurate 3D mapping of terrain and objects even in challenging environments.

SourceOptica·JournalOptica·DateApr 25, 2024
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Switching off the light to see better

Researchers from Osaka University have developed a new approach for super-resolution microscopy that can observe dense microstructures inside cells with excellent sharpness. By selecting only a desired plane to image using thin 'light sheet' illumination, they were able to achieve background-free super-resolution imaging.

SourceOsaka University·JournalNature Methods·TypeImaging analysis·DateApr 22, 2024

Advancing high-resolution ultrasound imaging with deep learning

Researchers developed a new method to accelerate high-resolution ultrasound localization microscopy using deep learning, enabling faster and more accurate imaging of microvascular structures. The technique, called LOCA-ULM, improves spatial resolution and processing speed while maintaining sensitivity for functional imaging.

SourceBeckman Institute for Advanced Science and Technology·JournalNature Communications·DateApr 22, 2024

A better view with new mid-infrared nanoscopy

A team at the University of Tokyo has constructed an improved mid-infrared microscope that enables them to see the structures inside living bacteria at the nanometer scale with a resolution of 120 nanometers. This breakthrough can aid multiple fields of research, including into infectious diseases.

SourceUniversity of Tokyo·JournalNature Photonics·TypeExperimental study·DateApr 17, 2024

Starving cells hijack protein transport stations

Researchers found that nutrient-starved cells divert ER exit sites to lysosomes for degradation, using a novel pathway to free up amino acids. This process involves the recruitment of molecules to direct ER exit sites to lysosomes, where they are destroyed and their components recycled.

SourceHoward Hughes Medical Institute·JournalDevelopmental Cell·DateApr 12, 2024
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Secrets of cell division revealed by cutting-edge imaging technique

A recent study using cutting-edge super-resolution microscopy has shed light on the role of cohesin in cell division. The research revealed multiple populations of cohesin complexes, each playing a specific role in faithful genetic material segregation during cell division.

SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalScience·TypeExperimental study·DateMar 8, 2024

Photon upconversion: Steering light with supercritical coupling

Researchers at National University of Singapore have developed supercritical coupling, a new approach that significantly enhances photon upconversion efficiency. This discovery challenges existing paradigms and opens a new direction in light emission control.

SourceNational University of Singapore·JournalNature·TypeExperimental study·DateFeb 22, 2024

Super-resolution microscopy harnesses digital display technology

Researchers developed a high-speed modulation system combining digital display with super-resolution imaging, significantly improving lateral and axial resolution. This enables detailed study of subcellular structures in animal cells and plant ultrastructures, paving the way for future biological discoveries.

SourceSPIE--International Society for Optics and Photonics·JournalAdvanced Photonics Nexus·DateFeb 14, 2024

A new way to visualize brain cancer

Researchers from Brigham and Women's Hospital and MIT unveiled a new microscopy technology called decrowding expansion pathology (dExPath) that provides novel insights into brain cancer development. The technology enables scientists to study neurological diseases at a never-before-achieved nanoscale level on conventional clinical samples.

SourceBrigham and Women's Hospital·JournalScience Translational Medicine·TypeObservational study·DateJan 31, 2024
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Mapping local quality at super-resolution scale

A team of scientists introduced a novel method to map local quality at super-resolution scale, enabling unparalleled resolution mapping and accurate error estimation. The technique, PANEL, was applied to various imaging approaches and showed improved SR image quality.

SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·JournalLight Science & Applications·DateJan 22, 2024

AI takes the reins in deep-tissue imaging

Researchers at Purdue University developed a novel AI engine to control and optimize optical microscopes, enabling 3D ultrastructure visualization of the brain circuitry with nanometer resolution. This technology has the potential to shed light on human development and disease, particularly autism and Alzheimer's disease.

SourcePurdue University·JournalNature Methods·DateDec 6, 2023

PicoRuler: molecular rulers for high-resolution microscopy

Researchers have developed PicoRulers, biocompatible molecular rulers for high-resolution microscopy. Using genetic code expansion and click chemistry, the team constructed customized molecular rulers based on the protein PCNA, enabling precise testing of super-resolution microscopy methods on cellular biomolecules.

SourceUniversity of Würzburg·JournalAdvanced Materials·TypeExperimental study·DateDec 1, 2023
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Universal adaptive optics for microscopy through embedded neural network control

A new machine learning-based adaptive optics method, MLAO, enhances microscopy imaging by requiring fewer sample exposures and coping with high noise levels, random sample motions, and blinking events. The approach provides physical insights into the imaging process, enabling better understanding of aberrations and internal workings.

SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·DateNov 16, 2023

Deep self-learning enables volumetric microscopy with 3D isotropic resolution

A new deep learning approach called Self-Net improves volumetric fluorescence microscopy's 3D resolution isotropy, enhancing image quality and enabling accurate analysis of complex biological structures. This method enables fast training and inference speed, promoting discoveries in life sciences.

SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·JournalLight Science & Applications·DateOct 11, 2023

Complex-domain neural network advances large-scale coherent imaging

A new complex-domain neural network enhances large-scale coherent imaging by exploiting latent coupling information between amplitude and phase components. The technique reduces exposure time and data volume significantly while maintaining high-quality reconstructions.

SourceSPIE--International Society for Optics and Photonics·JournalAdvanced Photonics Nexus·DateJul 27, 2023
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

LIONESS redefines brain tissue imaging

Scientists have developed a new technology called LIONESS, which allows for comprehensive and spatially resolved reconstruction of living brain tissue. This breakthrough enables observation and measurement of dynamic cellular biology in real-time.

SourceInstitute of Science and Technology Austria·JournalNature Methods·TypeImaging analysis·DateJul 10, 2023

New imaging technique is no last resort

Researchers created a new method, RESORT, to image and analyze living systems in unprecedented detail. The technique combines benefits of super-resolution fluorescence and vibrational imaging, allowing for high spatial resolution and analysis of complex interactions.

SourceUniversity of Tokyo·JournalScience Advances·TypeExperimental study·DateJun 16, 2023

New framework for super-resolution ultrasound

Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.

SourceBeckman Institute for Advanced Science and Technology·JournalIEEE Transactions on Medical Imaging·TypeImaging analysis·DateMay 25, 2023

Speckle structured illumination endoscopy

A new technique called speckle structured illumination endoscopy (SSIE) achieves super resolution in images acquired during endoscopy with a wide field of view and large depth of field. SSIE outperforms existing high-resolution endoscopic systems, which typically have limited field of view and depth of field.

SourceCompuscript Ltd·JournalOpto-Electronic Advances·DateMay 11, 2023
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Researchers publish findings from ‘super-resolution’ imaging technology

A team of researchers from the University of Oklahoma and Yale University has developed a super-resolution imaging platform technology to visualize nanoparticles within cells. The technique, called expansion microscopy, enables 3-D imaging with resolutions as low as 10 nanometers, allowing for safer and more efficient nanomedicines.

SourceUniversity of Oklahoma·JournalACS Nano·DateMay 9, 2023

Generation of color-tunable high-performance LG laser beams via Janus OPO

A team from Nanjing University and Sun Yat-Sen University developed a two-facing Janus OPO scheme for generating high-efficiency, high-purity broadband LG modes with tunable topological charge. The output LG mode has a tunable wavelength between 1.5 μm and 1.6 μm, with a conversion efficiency above 15 percent.

SourceSPIE--International Society for Optics and Photonics·JournalAdvanced Photonics Nexus·DateApr 24, 2023
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

High-speed super-resolution microscopy via temporal compression

Researchers developed temporal compressive super-resolution microscopy (TCSRM) to overcome optical diffraction's spatial resolution restriction. TCSRM achieves high-speed imaging at 1200 frames per second with a spatial resolution of 100 nanometers, enabling observation of fast dynamics in fine structures.

SourceSPIE--International Society for Optics and Photonics·JournalAdvanced Photonics·DateMar 10, 2023

Better microscopy technique for bioscience and live cell real-time imaging

A new SIM algorithm using principal component analysis (PCA-SIM) has been developed to enhance the accuracy and efficiency of real-time live-cell imaging. The algorithm achieves more accurate parameter estimation and superior noise immunity compared to conventional iterative correlation-based approaches.

SourceLight Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS·JournaleLight·DateFeb 6, 2023

Charting the human brain with new tools

Researchers are developing a comprehensive cell atlas for the human brain, which would cover billions of cells and provide a holistic description of its properties. Advanced visualization techniques have been developed to catalog brain regions and cell types, enabling better resolution and accuracy in studying neural circuits.

SourceSociety for Neuroscience·DateNov 9, 2022
Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Researchers capture how genes fold and work at unprecedented resolution

A new genome imaging technique captures the structure of the human genome at unprecedented resolution, revealing how individual genes fold and work. This technique, called Modeling immuno-OligoSTORM (MiOS), combines high-resolution microscopy and advanced computational modeling to provide a detailed picture of gene shape and function.

SourceCenter for Genomic Regulation·JournalNature Structural & Molecular Biology·TypeExperimental study·DateOct 13, 2022